Aortic DissectionNCT04450433
Functional Study of Metabolites in Patients With Aortic Dissection
An observational study of Aortic Dissection, run by Shenzhen People's Hospital at 1 site in China.
Trial summary
Research on metabolites in patients with aortic dissection, with a view to finding products with high or low metabolism in patients with aortic dissection, looking for metabolic factors related to the onset of aortic dissection, and further verifying the role of metabolic factors in disease through functional… Read more about this study
- Who is it for?
- Ages 30 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Aortic Dissection
- What is being tested?
- aortic dissection and healthy people
- How many people
- 1 participants
- Where
- 1 siteChina
- Study dates
- 1 Nov 2019to 30 Oct 2020
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: 30 patients with aortic dissection and 15 healthy people
Who may be able to join
- patients with Aortic dissection
Who cannot join
- Sepsis
Trial locations and contacts
1 site in 1 country.
China1 site, 1 recruiting
- Recruiting
Shenzhen People's Hospital
Shenzhen, Guangdong, 518020
Huadong Liu, PhD, 13724397998, lhd2578@163.com
About this study
Research on metabolites in patients with aortic dissection, with a view to finding products with high or low metabolism in patients with aortic dissection, looking for metabolic factors related to the onset of aortic dissection, and further verifying the role of metabolic factors in disease through functional verification The role of formation, and ultimately explore the early screening of potential aortic dissection patients
- Conditions
- Aortic Dissection
- Being tested
- aortic dissection and healthy people
- Medical subject headings
- Aortic Dissection
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
aortic dissection and healthy peopleDiagnostic test
Differential expression of metabolites in patients with aortic dissection and healthy people
| Study group | Role | What they receive |
|---|---|---|
| Baseline table of patients | Not described Receives: Diagnostic Test: aortic dissection and healthy people | |
| Differential metabolites of two groups of control patients | Not described Receives: Diagnostic Test: aortic dissection and healthy people | |
| Functional verification of differential metabolites | Not described Receives: Diagnostic Test: aortic dissection and healthy people |
What is being measured
The primary outcome is the main question the study is designed to answer.
Differential expression of metabolites in two groups of patients
Differential expression of metabolites in the two groups of patients, looking for metabolic factors related to the incidence of aortic dissection, and further verifying the function of metabolites through functional methods, with a view to finding high-risk metabolic factors for patients with aortic dissection
Measured: 2019-11----2021.01
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jun 2020
- Study start1 Nov 2019
- Primary completion30 Jul 2020 (estimated)
- Study completion30 Oct 2020 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Aortic DissectionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 1 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Shenzhen People's Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04450433
- Sponsor's protocol ID
- Liuhuadong's Research Group
- Status last verified
- Jun 2020
- First submitted
- 24 Jun 2020
- Last updated
- 29 Jun 2020
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 29 Jun 2020. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Functional Study of Metabolites in Patients With Aortic Dissection
- ClinicalTrials.gov ID
- NCT04450433
- Acronym / sponsor ID
- Liuhuadong's Research Group
- Conditions
- Aortic Dissection
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 1 participants (estimated)
- Lead sponsor
- Shenzhen People's HospitalUniversity, hospital or other
- Study start
- 1 Nov 2019 (actual)
- Primary completion
- 30 Jul 2020 (estimated)
- Study completion
- 30 Oct 2020 (estimated)
- First posted
- 29 Jun 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Research on metabolites in patients with aortic dissection, with a view to finding products with high or low metabolism in patients with aortic dissection, looking for metabolic factors related to the onset of aortic dissection, and further verifying the role of metabolic factors in disease through functional verification The role of formation, and ultimately explore the early screening of potential aortic dissection patients
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Baseline table of patients | – | Diagnostic Test: aortic dissection and healthy people |
| Differential metabolites of two groups of control patients | – | Diagnostic Test: aortic dissection and healthy people |
| Functional verification of differential metabolites | – | Diagnostic Test: aortic dissection and healthy people |
Who may qualify
- Ages
- 30 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- 30 patients with aortic dissection and 15 healthy people
Key inclusion criteria (1 listed)
- patients with Aortic dissection
Key exclusion criteria (1 listed)
- Sepsis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| aortic dissection and healthy peopleDifferential expression of metabolites in patients with aortic dissection and healthy people | Diagnostic test | Baseline table of patients, Differential metabolites of two groups of control patients, Functional verification of differential metabolites |
Primary outcome
Differential expression of metabolites in two groups of patients
Time frame: 2019-11----2021.01
Differential expression of metabolites in the two groups of patients, looking for metabolic factors related to the incidence of aortic dissection, and further verifying the function of metabolites through functional methods, with a view to finding high-risk metabolic factors for patients with aortic dissection
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jun 2020.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Aortic Dissection, run by Shenzhen People's Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 29 Jun 2020. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Huadong Liu (13724397998, lhd2578@163.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Differential expression of metabolites in two groups of patients (time frame: 2019-11----2021.01). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jun 2020; AzTrials last refreshed its copy on 6 Nov 2026.