Blood DonationNCT04484896
Message Framing on Recruiting Rh-D Negative Blood Donors
A study testing Gain-framed SMS message, Loss-framed SMS message and Information SMS message in people with Blood Donation, run by Guangzhou Blood Center at 1 site in China.
Trial summary
Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Blood Donation
- What is being tested?
- Gain-framed SMS message, Loss-framed SMS message and Information SMS message
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,082 participants
- Where
- 1 siteChina
- Study dates
- 22 Jul 2020to 30 Jul 2020
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- O and A Rh- negative blood donors Last donations were between January 1, 2018 and December 31, 2019
Who cannot join
- With an obviously invalid phone number Serological results of the last donation were positive
Trial locations and contacts
1 site in 1 country.
China1 site, 1 recruiting
- Recruiting
Guangzhou Blood Center
Guangzhou, Guangdong, 510095
Jian OUYANG, Master, 0086 15918771924, 434524249@qq.com
About this study
Official title: Effects of Message Framing on Recruiting Rh-D Negative Blood Donors in an Emergency Situation
Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 22, 2020 blood stockpile of O-negative and A-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and A-negative blood donors whose last donation dates were between January 1, 2018 and December 31, 2019 were identified and randomly assigned to four groups. Three different recruitment text messages were send three groups. We observed the re-donation rates among four groups within one week.
- Conditions
- Blood Donation
- Being tested
- Gain-framed SMS message, Loss-framed SMS message, Information SMS message
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gain-framed SMS messageOther
Emergency recruitment cell phone short messages that emphasizing donating blood can save patients' lives were sent to donors in this group.
Loss-framed SMS messageOther
Emergency recruitment cell phone short messages emphasizing that donating blood can prevent patients from death were sent to donors in this group.
Information SMS messageOther
Emergency recruitment cell phone short messages that only mentioning the low Rh-negative blood stockpile were sent to donors in this group.
| Study group | Role | What they receive |
|---|---|---|
| Gain-frame Message | Experimental | Short messaging service (SMS) message: Dear group O/A Rh-D negative blood donor:
Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to save lives. Thank you for your support.
Please bring your identification (ID) card and show this message to our staff. Thank you. Receives: Other: Gain-framed SMS message |
| Loss-frame Message | Experimental | SMS message: Dear group O/A Rh-D negative blood donor:
Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to prevent the loss of life. Thank you for your support.
Please bring your ID card and show this message to our staff. Thank you. Receives: Other: Loss-framed SMS message |
| Information Message | Experimental | SMS message: Dear group O/A Rh-D negative blood donor:
Hello! The inventory of group O/A Rh-D negative blood product is low at present, if you can, please consider donating blood again. Thank you for your support.
Please bring your ID card and show this message to our staff. Thank you. Receives: Other: Information SMS message |
| Control group | No intervention | Donors in this group were not received SMS reminders. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Re-donation rate
Intention-to-treat were applied. Re-donation rate was defined as the number of donors in each group divided by donors who re-donated within 7 days.
Measured: 7 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jul 2020
- Study start22 Jul 2020
- Primary completion29 Jul 2020 (estimated)
- Study completion30 Jul 2020 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Blood DonationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 1,082 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Guangzhou Blood Center
- Sponsor type
- Other government
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04484896
- Sponsor's protocol ID
- Recruiting Rh-D- blood donors
- Status last verified
- Jul 2020
- First submitted
- 21 Jul 2020
- Last updated
- 28 Jul 2020
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 28 Jul 2020. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Message Framing on Recruiting Rh-D Negative Blood Donors in an Emergency Situation
- ClinicalTrials.gov ID
- NCT04484896
- Acronym / sponsor ID
- Recruiting Rh-D- blood donors
- Conditions
- Blood Donation
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 1,082 participants (estimated)
- Lead sponsor
- Guangzhou Blood CenterOther government
- Study start
- 22 Jul 2020 (actual)
- Primary completion
- 29 Jul 2020 (estimated)
- Study completion
- 30 Jul 2020 (estimated)
- First posted
- 24 Jul 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 22, 2020 blood stockpile of O-negative and A-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and A-negative blood donors whose last donation dates were between January 1, 2018 and December 31, 2019 were identified and randomly assigned to four groups. Three different recruitment text messages were send three groups. We observed the re-donation rates among four groups within one week.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Gain-frame Message | Experimental | Other: Gain-framed SMS messageShort messaging service (SMS) message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to save lives. Thank you for your support. Please bring your identification (ID) card and show this message to our staff. Thank you. |
| Loss-frame Message | Experimental | Other: Loss-framed SMS messageSMS message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to prevent the loss of life. Thank you for your support. Please bring your ID card and show this message to our staff. Thank you. |
| Information Message | Experimental | Other: Information SMS messageSMS message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, if you can, please consider donating blood again. Thank you for your support. Please bring your ID card and show this message to our staff. Thank you. |
| Control group | No intervention | –Donors in this group were not received SMS reminders. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- O and A Rh- negative blood donors Last donations were between January 1, 2018 and December 31, 2019
Key exclusion criteria (1 listed)
- With an obviously invalid phone number Serological results of the last donation were positive
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gain-framed SMS messageEmergency recruitment cell phone short messages that emphasizing donating blood can save patients' lives were sent to donors in this group. | Other | Gain-frame Message |
| Loss-framed SMS messageEmergency recruitment cell phone short messages emphasizing that donating blood can prevent patients from death were sent to donors in this group. | Other | Loss-frame Message |
| Information SMS messageEmergency recruitment cell phone short messages that only mentioning the low Rh-negative blood stockpile were sent to donors in this group. | Other | Information Message |
Primary outcome
Re-donation rate
Time frame: 7 days
Intention-to-treat were applied. Re-donation rate was defined as the number of donors in each group divided by donors who re-donated within 7 days.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Jul 2020.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gain-framed SMS message, Loss-framed SMS message and Information SMS message in people with Blood Donation, run by Guangzhou Blood Center at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 28 Jul 2020. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Jian OU-YANG (+8615918771924, 434524249@qq.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Re-donation rate (time frame: 7 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Jul 2020.