Clinical trials: Blood Donation
Iron Deficiency
Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality
Primary Hypothesis The 24-hour post-transfusion RBC recovery of units obtained from donors exhibiting iron-deficient erythropoiesis will not meet FDA standards for clinical use.
- Trial name
- DIDS (NCT02889133)
- Testing
- Iron-dextran, Saline, Blood Donation
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Columbia University
Ferritin, Insulin Sensitivity
Blood Donation Could Improve Insulin Sensitivity
Studies in the literature suggest that people with obesity have an excess of stored iron. There is possibly an inverse relationship between ferritin levels and the actions of insulin on glycemic control.
- Conditions
- Ferritin, Insulin Sensitivity, Blood Donation
- Trial name
- GLUCFER (NCT05791968)
- Testing
- Whole blood standard donation
- Where
- Spain
- Volunteers
- 89 people
- Sponsor
- University of Castilla-La Mancha
Blood Donors
Community-Based Communication Approaches for Blood Donation in Ghana
DESIGN This pilot study utilizes a mixed-methods approach to develop a novel docu- drama communication strategy, design WhatsApp intervention, evaluate the feasibility of a larger pragmatic randomized controlled trial (RCT) of…
- Trial name
- C-CAD (NCT04783077)
- Testing
- WhatsApp, Control, Docudrama
- Where
- Ghana
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Blood Donors, Traumatic Blood Loss
Comparison of the Accuracy of Non-invasive Hemoglobin Measurement (SpHb) and Vena Cava Inferior Ultrasound
The aim of this work is determine the more successful noninvasive method by comparison of two noninvasive methods ( IVC ultrasound - noninvasive hemoglobin measurement (SpHb)) that used in the detection of patients with blood…
- Trial name
- NCT02944851
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Healthy
The Effect of Blood Donation on Hematological and Iron Indices and Detection of Autologous Blood Transfusion
Blood donations is a essential and crucial in the clinic. Normal biological variation of relevant biomarkers and hormones before the donation of 450 mL whole blood as well as the expected alterations in systemic levels of plasma…
- Trial name
- NCT04514978
- Testing
- Blood donation and blood transfusion
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Anemia, Blood Transfusion
A Study of the Safety and Effectiveness of Epoetin Alfa in Facilitating Self-donation of Blood Before Surgery in Patients Who Are Undergoing Orthopedic Surgery and Who Have Low Hematocrit Levels (the Percent of Red Blood Cells in Whole Blood)
The purpose of this study is to evaluate the safety and effectiveness of epoetin alfa and to determine whether epoetin alfa will facilitate self-donation of blood before surgery in patients who have anemia, (as indicated by low…
- Conditions
- Anemia, Blood Transfusion, Orthopedic Procedures
- Trial name
- NCT00270114
- Testing
- epoetin alfa
- Volunteers
- 55 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Anemia
A Study to Evaluate the Effectiveness and Safety of Epoetin Alfa During the Period When One is Donating One's Own Blood Before Surgery.
The purpose of this study is to evaluate the whether epoetin alfa stimulates the bone marrow to produce red blood cells and therefore increases a patient's ability to self-donate blood prior to major surgery.
- Trial name
- NCT00270179
- Testing
- epoetin alfa
- Volunteers
- 17 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Iron Deficiency
Microbiome of Donor Iron Deficient Study
The goal of this pilot study is to test whether the microbiome is affected by intravenous iron repletion.
- Trial name
- NCT02990988
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Columbia University
Blood Donation
Recruit Blood Donors Via SMS During Epidemic of COVID-19
The fight against the spread of the 2019-nCoV epidemic has achieved some success in China, but the epidemic is far from over. A key factor making the epidemic under control in China is the government's call for social distance…
- Trial name
- NCT04370886
- Testing
- blood donation SMS
- Where
- China
- Volunteers
- 456,517 people
- Sponsor
- Guangzhou Blood Center
Blood Donation
Attitudes About Blood Donation
The study evaluates the knowledge, attitude and practice about blood donation among medical students and medical staff in Poland.
- Trial name
- KAPsurvey (NCT02281565)
- Testing
- survey
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Blood Donation
BLOODSAFE Ghana- Iron and Nutritional Counselling Strategy
A randomized trial will compare 6-months of low-dose (65mg elemental iron daily) among prospective blood donors who are deferred for low haemoglobin but have passed all of the other pre-screening requirements for blood donation…
- Trial name
- UH3BLIS (NCT06101238)
- Testing
- supplementation with low dose elemental iron
- Where
- United States
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Scoliosis
Recombinant Human Erythropoietin Compared to Autologous Pre-Donation Prior to Scoliosis Surgery in Children.
The purpose of this study is to establish whether rHuEpo is as effective as PAD in increasing red cell mass prior to surgery. Other benefits of the PAD program and preoperative administration of rHuEpo will also be compared.
- Trial name
- NCT00323752
- Testing
- rHuEpo
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Fluid Loss
Clinical Evaluation of the CM-1500 During Apheresis Blood Donation
The study is a prospective, single-arm, non-randomized, non-blinded, non-controlled, non-significant risk, single center study enrolling up to 200 healthy adult subjects consented to undergo an apheresis donation procedure.
- Trial name
- NCT05012462
- Testing
- CM-1500, CM-1600
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Zynex Monitoring Solutions
Complement Mediated Bacterial Killing in Healthy Adults
Complement 2: Blood Donations to Develop Vaccines Against Infectious Diseases
We need human blood to understand the immune response to infection and to test promising new vaccines against infectious diseases in the laboratory.
- Trial name
- C2 (NCT01945307)
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hypertension
Effect of Blood Donation on Blood Pressure, Iron Metabolism, Oxidative Stress
The investigators want to investigate the effects of blood donation to blood pressure, to iron metabolism and oxidative stress. There are results of other studies that show, that there is a positive effect of blood donation to…
- Trial name
- NCT01553409
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy
AMD 3100 (Mozobil Plerixafor) to Mobilize Stem Cells for Donation
Peripheral blood progenitor cells (PBPC) have become the preferred source of hematopoetic stem cells for allogeneic transplantation because of technical ease of collection and shorter time required for engraftment.
- Trial name
- NCT00075335
- Testing
- AMD3100 (Mozobil plerixafor)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Anemia
A Study to Evaluate the Safety of Epoetin Alfa and Its Effectiveness in Facilitating the Presurgical Collection of Blood From Anemic Patients for Possible Self-transfusion During and After Scheduled Joint Surgery.
The purpose of this study is to evaluate the safety of epoetin alfa and its effectiveness in facilitating the presurgical collection of blood from anemic patients for possible self-transfusion during and after scheduled joint…
- Trial name
- NCT00270062
- Testing
- epoetin alfa
- Volunteers
- 77 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Healthy Volunteers, Syphilis Serologic Assay Development
Blood Donation Study for ALPCO Syphilis-T and Syphilis-NT Assay Development
This prospective, single-center study will collect blood from approximately 50 adult volunteers aged 22 years or older. Participants will provide informed consent, complete an eligibility review, and undergo one blood draw of…
- Conditions
- Healthy Volunteers, Syphilis Serologic Assay Development, Blood Specimen Collection, Diagnostic Assay Development
- Trial name
- NCT07830550
- Testing
- ALPCO Syphilis-T, ALPCO Syphilis-NT CLIA Kits
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Increase Repeat Blood Donation Attempts Among First-time Donors
Community-based Communication for Blood Donation in Ghana
A randomized controlled trial to evaluate the effectiveness of the WhatsApp groups or docudrama compared to a control group (usual engagement with blood services) on repeat blood donation attempts among first-time blood donors in…
- Trial name
- C-CAD (NCT05973890)
- Testing
- WhatsApp, docudrama
- Where
- United States
- Volunteers
- 882 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Blood Donation, Happiness
Blood Donation and Subjective Well-being
This study investigates the psychological effects of blood donation among adult donors at the Guangzhou Blood Center. The primary objective is to examine whether a brief gratitude-based intervention delivered after donation…
- Trial name
- NCT05213130
- Testing
- Information
- Where
- China
- Volunteers
- 601 people
- Sponsor
- Guangzhou Blood Center