Trigger FingerTriggerhappyNCT04568993
The TriggerHappy Trial
A study testing Proximal phalangeal level and Volar to the MCP-joint in people with Trigger Finger and Trigger Thumb, run by Sahlgrenska University Hospital at 1 site in Sweden.
Trial summary
This is a prospective randomized multicenterstudy focusing on PROMs after primary corticoid injection for triggerfinger with a comparison of two different injection techniques. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Trigger Finger, Trigger Thumb, Minimally Invasive Surgery
- What is being tested?
- Proximal phalangeal level and Volar to the MCP-joint
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteSweden
- Study dates
- 1 Oct 2020to 1 Jul 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Triggering of one or more fingers and/or impaired active finger motion and/or pain during active finger motion
- Localized tenderness volar to the MCP joint of the affected finger
- The patient seeks treatment
Who cannot join
- Previous treatment for triggerfinger in the finger to be treated
- Impaired function of finger due to previous trauma/infection or other condition
- Suspicion of other cause than triggeriinger/tendovaginitis
- Patient not able to follow instructions
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Patient-reported Outcome After Corticoid Injection for Triggerfinger- a Randomized Controlled Study Between Two Injection Procedures and Between Corticoid Injection and Percutaneous Release
This is a prospective randomized multicenterstudy focusing on PROMs after primary corticoid injection for triggerfinger with a comparison of two different injection techniques.
Read the detailed description
This study aims to compare two different methods of corticosteroid injections in patients with triggerfinger, and to study the effects of these injections by day-to-day self-assessment by the included study persons for four weeks. The patient assess: 1. Pain 2. Motion and 3. Triggering by VAS scale every day for four weeks.
- Conditions
- Trigger Finger, Trigger Thumb, Minimally Invasive Surgery
- Being tested
- Proximal phalangeal level, Volar to the MCP-joint
- Medical subject headings
- Trigger Finger Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Proximal phalangeal levelProcedure or surgery
Injection of methyl prednisone and lidocaine in the tendon sheet at the level of the proximal phalanx
Volar to the MCP-jointDrug
Injection of methyl prednisone and lidocaine in the tendon sheet volar to the MCP-joint
| Study group | Role | What they receive |
|---|---|---|
| proximal phalangeal level | Experimental | injection in the the tendon sheet over proximal phalanx of finger Receives: Procedure: Proximal phalangeal level |
| volar MCP level | Active comparator | injection above the A1 pulley volar to the MCP joint Receives: Drug: Volar to the MCP-joint |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain after injection
Visual analouge scale (VAS), range 0-10, where 0 indicates "no pain" and 10 "maximum pain"
Measured: Four weeks
Impairment of finger motion
Visual analouge scale (VAS), range 0-10, where 0 indicates "no impairment" and 10 "maximum impairment"
Measured: Four weeks
Triggering
Visual analouge scale (VAS), range 0-10, where 0 indicates "no trigger phenomenon" and 10 "Trigger phenomenon all the time/ locked finger"
Measured: Four weeks
Secondary outcomes (1)
Quick-DASH
generic handquestionaire, 11 items, 0 means normal hand function, 100 most impaired function
Measured: Four weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Sep 2020
- Study start1 Oct 2020
- Primary completion1 Nov 2027 (estimated)
- Study completion1 Jul 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Trigger FingerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Prospective randomized controlled trial
- Masking
- None (open label)
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sahlgrenska University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Joakim Stromberg, Sahlgrenska University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04568993
- Sponsor's protocol ID
- The TriggerHappy Trial
- Acronym
- Triggerhappy
- Status last verified
- Oct 2025
- First submitted
- 23 Sep 2020
- Last updated
- 24 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Patient-reported Outcome After Corticoid Injection for Triggerfinger- a Randomized Controlled Study Between Two Injection Procedures and Between Corticoid Injection and Percutaneous Release
- ClinicalTrials.gov ID
- NCT04568993
- Acronym / sponsor ID
- Triggerhappy / The TriggerHappy Trial
- Conditions
- Trigger Finger, Trigger Thumb, Minimally Invasive Surgery
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Sahlgrenska University HospitalUniversity, hospital or other
- Study start
- 1 Oct 2020 (actual)
- Primary completion
- 1 Nov 2027 (estimated)
- Study completion
- 1 Jul 2028 (estimated)
- First posted
- 29 Sep 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a prospective randomized multicenterstudy focusing on PROMs after primary corticoid injection for triggerfinger with a comparison of two different injection techniques.
Detailed description
This study aims to compare two different methods of corticosteroid injections in patients with triggerfinger, and to study the effects of these injections by day-to-day self-assessment by the included study persons for four weeks. The patient assess: 1. Pain 2. Motion and 3. Triggering by VAS scale every day for four weeks.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Prospective randomized controlled trial
| Arm | Type | Receives |
|---|---|---|
| proximal phalangeal level | Experimental | Procedure: Proximal phalangeal levelinjection in the the tendon sheet over proximal phalanx of finger |
| volar MCP level | Active comparator | Drug: Volar to the MCP-jointinjection above the A1 pulley volar to the MCP joint |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Triggering of one or more fingers and/or impaired active finger motion and/or pain during active finger motion
- Localized tenderness volar to the MCP joint of the affected finger
- The patient seeks treatment
Key exclusion criteria (4 listed)
- Previous treatment for triggerfinger in the finger to be treated
- Impaired function of finger due to previous trauma/infection or other condition
- Suspicion of other cause than triggeriinger/tendovaginitis
- Patient not able to follow instructions
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Proximal phalangeal levelInjection of methyl prednisone and lidocaine in the tendon sheet at the level of the proximal phalanx | Procedure or surgery | proximal phalangeal level |
| Volar to the MCP-jointInjection of methyl prednisone and lidocaine in the tendon sheet volar to the MCP-joint | Drug | volar MCP level |
Primary outcome
Pain after injection
Time frame: Four weeks
Visual analouge scale (VAS), range 0-10, where 0 indicates "no pain" and 10 "maximum pain"
Impairment of finger motion
Time frame: Four weeks
Visual analouge scale (VAS), range 0-10, where 0 indicates "no impairment" and 10 "maximum impairment"
Triggering
Time frame: Four weeks
Visual analouge scale (VAS), range 0-10, where 0 indicates "no trigger phenomenon" and 10 "Trigger phenomenon all the time/ locked finger"
1 secondary outcome
Quick-DASH
Time frame: Four weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Apr 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Proximal phalangeal level and Volar to the MCP-joint in people with Trigger Finger and Trigger Thumb, run by Sahlgrenska University Hospital at 1 site in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 24 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain after injection (time frame: Four weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Apr 2026.