Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLMNCT04741269
Asymmetric Lack of Knee Flexion as a Symptom of DLM in Children
An observational study of Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLM, run by Hospices Civils de Lyon at 1 site in France.
Trial summary
Highlighted during the clinical examination of a knee flexion asymmetry, and related to the intraoperative meniscal observations on DLM. Search for a link between asymmetric bending defect and posterior shift in MCA-type DLM. Analysis of all patients with symptomatic DLM. Read more about this study
- Who is it for?
- Ages 0 to 18 years
- Conditions the study is for
- Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLM
- What is being tested?
- Find a link between lack of knee flexion and meniscal posterior luxation fixed
- How many people
- 98 participants
- Where
- 1 siteFrance
- Study dates
- 1 Sep 2020to 31 Dec 2020
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 0 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Study population: Children with a discoid lateral meniscus symptomatic and surgical care.
Who may be able to join
- < 18 yo
- Symptomatic discoid lateral meniscus
Who cannot join
- Osteochondritis dissecans (OCD)
- Asymptomatic and partial DLM observed during arthroscopic exploration for other reasons
- Revision knee surgery
Trial locations and contacts
1 site in 1 country.
France1 site
Paediatric orthopaedic - Femme Mère Enfant Hospital (HFME)
Lyon, 69005
About this study
Highlighted during the clinical examination of a knee flexion asymmetry, and related to the intraoperative meniscal observations on DLM.
Search for a link between asymmetric bending defect and posterior shift in MCA-type DLM.
Analysis of all patients with symptomatic DLM.
- Being tested
- Find a link between lack of knee flexion and meniscal posterior luxation fixed
- Keywords
- discoid lateral meniscus, children, instability, arthroscopy, repair, lack of flexion, flexion block knee
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Find a link between lack of knee flexion and meniscal posterior luxation fixedDiagnostic test
Measure the full flexion angle of the knee using a goniometer. Measure the heel-buttom distance. All measurements are carried out in bilateral and comparative ways.
Search for the meniscal position on MRI and intraoperatively: no shift, anterior, medial, posterior shift.
| Study group | Role | What they receive |
|---|---|---|
| Lack of knee flexion | During preoperative clinical exam, highlight of a lack of knee flexion. The lack of knee flexion consists in an asymmetric heel-bottom distance or an asymmetric goniometric measure of knee flexion.
All others characteristics are also analyzed like in group 2, as : rest of knee motion, MRI meniscus shift, arthroscopic shift Receives: Diagnostic Test: Find a link between lack of knee flexion and meniscal posterior luxation fixed | |
| Full knee flexion | During preoperative clinical exam, highlight of a lack of knee flexion. The lack of knee flexion consists in an asymmetric heel-bottom distance or an asymmetric goniometric measure of knee flexion. Patients in group 2 don't have any asymmetric full knee flexion. All others characteristics are also analyzed like in group 2, as : rest of knee motion, MRI meniscus shift, arthroscopic shift |
What is being measured
The primary outcome is the main question the study is designed to answer.
Meniscal posterior shift per-operative
Visualization of a dislocated posterior meniscus during arthroscopy, before any reduction or meniscoplasty procedure
Measured: During surgery for MCA-type DLM
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Feb 2021
- Study start1 Sep 2020
- Primary completion1 Nov 2020
- Study completion31 Dec 2020
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLMStudies of the same condition, open and under way.
- More trials run by Hospices Civils de LyonThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Retrospective
- Enrolment
- 98 participants (actual)
Sponsor and investigators
- Lead sponsor
- Hospices Civils de Lyon
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Nicolas CANCE, MD, Principal investigator, Paediatric orthopaedic - Femme Mère Enfant Hospital (HFME)
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04741269
- Sponsor's protocol ID
- 69HCL20_1241
- Status last verified
- Dec 2025
- First submitted
- 2 Feb 2021
- Last updated
- 19 Dec 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Asymmetric Lack of Knee Flexion as a Symptom of DLM in Children
- ClinicalTrials.gov ID
- NCT04741269
- Acronym / sponsor ID
- 69HCL20_1241
- Keywords
- discoid lateral meniscus, children, instability, arthroscopy, repair, lack of flexion, flexion block knee
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 98 participants (actual)
- Lead sponsor
- Hospices Civils de LyonUniversity, hospital or other
- Study start
- 1 Sep 2020 (actual)
- Primary completion
- 1 Nov 2020 (actual)
- Study completion
- 31 Dec 2020 (actual)
- First posted
- 5 Feb 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Highlighted during the clinical examination of a knee flexion asymmetry, and related to the intraoperative meniscal observations on DLM.
Search for a link between asymmetric bending defect and posterior shift in MCA-type DLM.
Analysis of all patients with symptomatic DLM.
Study design
- Observational model
- Other
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Lack of knee flexion | – | Diagnostic Test: Find a link between lack of knee flexion and meniscal posterior luxation fixedDuring preoperative clinical exam, highlight of a lack of knee flexion. The lack of knee flexion consists in an asymmetric heel-bottom distance or an asymmetric goniometric measure of knee flexion. All others characteristics are also analyzed like in group 2, as : rest of knee motion, MRI meniscus shift, arthroscopic shift |
| Full knee flexion | – | –During preoperative clinical exam, highlight of a lack of knee flexion. The lack of knee flexion consists in an asymmetric heel-bottom distance or an asymmetric goniometric measure of knee flexion. Patients in group 2 don't have any asymmetric full knee flexion. All others characteristics are also analyzed like in group 2, as : rest of knee motion, MRI meniscus shift, arthroscopic shift |
Who may qualify
- Ages
- 0 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
- Study population
- Children with a discoid lateral meniscus symptomatic and surgical care.
Key inclusion criteria (2 listed)
- < 18 yo
- Symptomatic discoid lateral meniscus
Key exclusion criteria (3 listed)
- Osteochondritis dissecans (OCD)
- Asymptomatic and partial DLM observed during arthroscopic exploration for other reasons
- Revision knee surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Find a link between lack of knee flexion and meniscal posterior luxation fixedMeasure the full flexion angle of the knee using a goniometer. Measure the heel-buttom distance. All measurements are carried out in bilateral and comparative ways. Search for the meniscal position on MRI and intraoperatively: no shift, anterior, medial, posterior shift. | Diagnostic test | Lack of knee flexion |
Primary outcome
Meniscal posterior shift per-operative
Time frame: During surgery for MCA-type DLM
Visualization of a dislocated posterior meniscus during arthroscopy, before any reduction or meniscoplasty procedure
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Dec 2025.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Nicolas CANCE, MD principal investigator
Paediatric orthopaedic - Femme Mère Enfant Hospital (HFME)
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLM, run by Hospices Civils de Lyon at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Meniscal posterior shift per-operative (time frame: During surgery for MCA-type DLM). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Dec 2025.