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NeurosciencesNCT04868929

The Brain Activation During Different Motor Patterns in Healthy Adults

An observational study of Neurosciences, run by National Taiwan University Hospital at 1 site in Taiwan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF). In addition, the relations between brain activation and motor performance will also be explored. Read more about this study

Who is it for?
Ages 20 to 30 yearsHealthy volunteers can take part
Conditions the study is for
Neurosciences
How many people
43 participants
Where
1 siteTaiwan
Study dates
1 May 2021to 7 Aug 2022
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 30 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Study population: The population in this study are heathly adults.

Who may be able to join

  • Age between 20 to 30 years.
  • Right-handed.
  • Ability to walk 30 meters independently without an assistive device.
  • No neurogical, cardiopulmonary, or muscle diseases that might interfere with the experiment.
  • Mini-Mental State Examination (MMSE) score greater than 24.
  • Exclusion Criteria 1. Physiological condition is unstable.

Who cannot join

None listed.

Trial locations and contacts

1 site in 1 country.

Taiwan1 site

  • National Taiwan University Hospital

    Taipei

Other trials in Taiwan

About this study

Official title: The Brain Activation During Motor Execution, Motor Imagery, Action Observation, and Mirror Visual Feedback in Healthy Adults

This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF). In addition, the relations between brain activation and motor performance will also be explored. This study includes two parts, which are upper limb and lower limb part. While executing all the tasks, brain activation in primary motor cortex(M1), premotor cortex(PMC), and supplementary motor cortex(SMA) will be monitored by functional near-infrared spectroscopy. One-way ANOVA with repeated measure will be used to detect the differences of brain activation level between each mode. Pearson correlation coefficient will be used to determine the relations of brain activation and motor performance.

Read the detailed description

In upper limb part, subjects will be instructed to execute functional reaching task in ME, MI, AO, and MVF mode. During ME mode, motor performance including maximum speed, maximum acceleration, and jerk will be collected simultaneously. In the lower limb part, subjects will be instructed to walking over ground in ME, MI, and AO mode. During ME mode, the temporal and spatial gait parameters, including speed, stride time, cadence, and stride length will be collected.

Conditions
Neurosciences
Keywords
brain activation, near infrared spectroscopy, motor imagery, action observation, mirror visual feedback

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Brain activities over primary motor cortex

    A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.

    Measured: Day 1

  2. Brain activities over premotor cortex

    A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.

    Measured: Day 1

  3. Brain activities over supplementary motor area

    A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.

    Measured: Day 1

Secondary outcomes (7)

  1. Motor performance of upper limb -maximum speed

    cm/s

    Measured: Day 1

  2. Motor performance of upper limb -maximum acceleration

    cm/s^2

    Measured: Day 1

  3. Motor performance of upper limb - jerk

    cm/s^3

    Measured: Day 1

  4. Motor performance of lower limb - gait speed

    cm/s

    Measured: Day 1

  5. Motor performance of lower limb - cadence

    steps

    Measured: Day 1

  6. Motor performance of lower limb - stride time

    second

    Measured: Day 1

  7. Motor performance of lower limb - stride length

    cm

    Measured: Day 1

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted3 May 2021
  2. Study start1 May 2021
  3. Primary completion7 Aug 2022
  4. Study completion7 Aug 2022

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Case crossover
Time perspective
Cross-sectional
Enrolment
43 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT04868929
Sponsor's protocol ID
202102037RINA
Status last verified
Jun 2022
First submitted
25 Apr 2021
Last updated
22 Feb 2023
Results posted
No
Data monitoring committee
No

Questions about this trial

What is this clinical trial studying?

An observational study of Neurosciences, run by National Taiwan University Hospital at 1 site in Taiwan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 22 Feb 2023. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Brain activities over primary motor cortex (time frame: Day 1). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04868929.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Feb 2023.

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