Clinical trials: Neurosciences
Neurological Disorders, Neuroscience
Advanced Space-time Resolved Techniques for Functional Neuroimaging at 7 Tesla MRI
In recent years, the in vivo study of the central nervous system has undergone significant advancement through the implementation of magnetic resonance imaging (MRI)-based neuroimaging techniques.
- Conditions
- Neurological Disorders, Neuroscience, Epilepsy, Brain Injuries, Focal
- Trial name
- AURORA (NCT07865546)
- Testing
- Functional neuroimaging
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Imago 7 Fondazione di Ricerca onlus
Pain, Disability
Additional Effects of Pain Neuroscience Education With Standard Pre-operative Physiotherapy on Post-laminectomy Pain and Disability.
This randomized controlled trial investigates whether adding Pain Neuroscience Education (PNE) to standard pre-operative physiotherapy improves outcomes after lumbar laminectomy.
- Conditions
- Pain, Disability, Laminectomy, Physical Therapy
- Trial name
- NCT07801586
- Testing
- Experimental Group - Pain Neuroscience Education + Standard Pre-operative Protocol, Control Group - Standard Pre-Operative Care
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Neurosciences
Studying the Neuronal Basis of Human Social Cognition
This proposal aims to study the role that the dorsal prefrontal cortex plays in human social cognition.
- Trial name
- NCT05324579
- Testing
- Behavioral testing during neuronal recordings
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pain, Pediatrics
Pain Neuroscience Education for Middle School Students
This project was designed as a single-blind, randomised controlled, prospective intervention study. The research question of the project is 'Is pain neuroscience education an effective method to improve various aspects of child…
- Conditions
- Pain, Pediatrics, Neuroscience Pain Education, Physical Activity
- Trial name
- NCT06869369
- Testing
- Turkish PNE4Kids
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Neurosciences
REALITY MONITORING AND DOPAMINE
Reality-monitoring characterizes the ability to determine whether information was perceived in the environment or only imagined .
- Trial name
- MORDOR (NCT05711082)
- Testing
- Précurseur de la dopamine, antagoniste D2
- Where
- France
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Neuroscience, Neuromodulation
Study of the Dynamics of Verbal and Non-verbal Interaction in Healthy Subjects, Through the Recording of Body Movements and Non-invasive Neurophysiological Techniques
Based on study literature, the investigators can say that our study aims to give an explanation not only from a behavioral point of view but also with respect to what are the neuronal mechanisms underlying our ability to perceive…
- Trial name
- OMNIBUS2023 (NCT06251479)
- Testing
- behavioral 1, behavioral 2, neuromodulation 1
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Dystonia, Neurologic Disorder
Study of Behavioral Dysfunctions and Related Neuronal Correlates in Patients With Dystonia
Dystonias represent hyperkinetic movement disorders characterized by protracted muscle contractions, such as to cause torsional movements and anomalous postures in different parts of the body.
- Conditions
- Dystonia, Neurologic Disorder, NEUROSCIENCE
- Trial name
- D-DIST (NCT06264063)
- Testing
- control group, experimental group, EEG power in alpha band
- Where
- Italy
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Neurosciences
Brain Networks Involved in Inner World Control
Inner speech (the "little voice" in our heads) plays a central role in our ability to perform complex cognitive tasks such as problem solving, reading, writing, thinking, and self awareness.
- Trial name
- INNERWORLD (NCT07469631)
- Testing
- Neuropsychological evaluation, questionnaires, and training on the tasks that will be performed in the MRI., MRI visits
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pain, Chronic Pain
Exploring the Feasibility of Using Virtual Reality as an Educational Tool in Chronic Pain Rehabilitation
Introduction: Chronic pain significantly impacts quality of life and requires comprehensive management strategies. Traditional pain education programs are beneficial but often require significant and prolonged patient engagement.
- Conditions
- Pain, Chronic Pain, Chronic Pain (Back / Neck), Adults
- Trial name
- NCT07434804
- Testing
- 6-Week Virtual reality-delivered pain science education and behavioural pain management program
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- University College Dublin
Myofascial Pain Syndromes, Neuroscience Pain Education
Pain Neuroscience Education in Myofascial Pain Syndrome
Background This study aimed to evaluate the additive effect of Pain Neuroscience Education (PNE), which addresses the biopsychosocial and neurophysiological foundations of pain, on conventional physiotherapy in myofascial pain…
- Conditions
- Myofascial Pain Syndromes, Neuroscience Pain Education, Physical Therapy Modalities
- Trial name
- NCT07410221
- Testing
- Conventional physiotherapy, Exercise, Pain neuroscience education (PNE)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Chronic Low Back Pain, Manual Therapy
Neuroscience Pain Education in Patients with Chronic Low Back Pain
The cognitive educational strategies such as neuroscience pain education, has been a popular and promising technique for treatment patients with chronic pain.
- Conditions
- Chronic Low Back Pain, Manual Therapy, Neuroscience Pain Education
- Trial name
- NCT03886636
- Testing
- neuroscience pain education, manual therapy, home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Kutahya Health Sciences University
Neurosciences, MRI
OPTIMIZATION of ADVANCED MR SEQUENCES
This monocentric methodological study aims at optimizing advanced MR sequences for image quality (reduced artefacts, signal to noise ratio, acquisition time, stability of quantitative measurements) on a new MR unit dedicated to…
- Conditions
- Neurosciences, MRI, Brain Tumor, Mental Disorders
- Trial name
- OPT-IRM (NCT05618990)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Neurosciences, Substance-Related Disorders
Neural Mechanisms of Cannabinoid-impaired Decision-Making in Emerging Adults
Emerging adults are a particularly vulnerable group for experiencing the immediate and potentially lifelong negative impacts of habitual cannabis use, and trends suggest that cannabis use disorder (CUD) will soon escalate in this…
- Conditions
- Neurosciences, Substance-Related Disorders, Behavior Problem
- Trial name
- NCT03944954
- Testing
- Marinol 10Mg Capsule TMS Real
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Michael J. Wesley, PhD
Chronic Neck Pain, Persistent Neck Pain
The Effects of Neuroscience-Based Exercise
The aim of this study is to examine the effects of neuroscience-based exercise approaches on pain, disability and gait parameters in individuals with non-specific chronic neck pain.
- Conditions
- Chronic Neck Pain, Persistent Neck Pain, Neuroscience Approach
- Trial name
- NBE (NCT05788263)
- Testing
- neuroscience based aproach
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fatih Tekin
Biomechanics, Anatomy, Psychology, Neuroscience, Ethnomusicology Method, qi Gong
INVESTIGATION OF THE EFFECTS OF BAPNE AND QI GONG EXERCISES ON BALANCE AND QUALITY OF LIFE IN INDIVIDUALS OVER 60
Geriatric problems develop with aging in individuals over 60 years of age. These problems include muscle weakness, balance disorders and changes in quality of life.
- Conditions
- Biomechanics, Anatomy, Psychology, Neuroscience, Ethnomusicology Method, qi Gong, Quality of Life, Balance
- Trial name
- NCT06106217
- Testing
- bapne, qi gong
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Fibromyalgia, Executive Function
Effectiveness Pain Neuroscience Education In The Executive Functions In Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic, complex and disabling clinical entity that has an average global prevalence of 2.7%. It occurs mainly in women in a 3: 1 ratio.
- Conditions
- Fibromyalgia, Executive Function, Neuroscience
- Trial name
- PNE (NCT05084300)
- Testing
- Pain Neuroscience Education, Usual care
- Where
- 2 sites in Colombia, Mexico
- Volunteers
- 62 people
- Sponsor
- Instituto Neurociencia Del Dolor
Neurosciences
The Brain Activation During Different Motor Patterns in Healthy Adults
This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF).
- Trial name
- NCT04868929
- Where
- Taiwan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Visual Neurosciences
Evaluation of Visual Parameters by Visual Evoked Potentials Captured by EEG
This project will be based on an approach that has already proven itself in the field of the development of low-level visual functions such as visual acuity, vernier acuity and contrast sensitivity (Norcia \& Tyler, 1985)…
- Trial name
- NCT05675852
- Testing
- 68-electrode electroencephalography with steady state visual evoked potentials
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Executive Function, Neurosciences
Different Domains of Executive Function Dual Task Walking on Brain Activation and Gait Performance in Healthy Adults
The aim of this study is to investigate the effects of different domains of executive function (EF) during dual task walking condition on brain activation and gait performance in healthy adults.
- Trial name
- NCT04905186
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital