Anxiety DisordersUP-CNCT04932421
Unified Protocol for Children: A Randomized Controlled Trial for the Portuguese Population
A study testing Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C) and ABC of Emotions in people with Anxiety Disorders and Mood Disorders, run by University of Coimbra at 1 site in Portugal.
Trial summary
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) is a transdiagnostic and emotion-focused cognitive-behavioral group intervention for children aged 6-12 years old with emotion disorders (i.e., anxious and/or mood disorders) and their parents. Read more about this study
- Who is it for?
- Ages 6 to 13 years
- Conditions the study is for
- Anxiety Disorders, Mood Disorders, Emotional Disorder
- What is being tested?
- Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C) and ABC of Emotions
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 153 participants
- Where
- 1 sitePortugal
- Study dates
- 1 Mar 2021to 30 Nov 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 13 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Children aged 6-13
- Primary diagnosis of an anxiety and/or depression disorder
- Speaking, reading and understanding Portuguese
Who cannot join
- Diagnosis of a psychotic disorder, bipolar disorder or intellectual disability;
- Severe current suicidal/homicidal ideation;
- The child is not on a stable dose of a psychotropic or other type of medication for at least 1 month prior to T0 assessment.
Trial locations and contacts
1 site in 1 country.
Portugal1 site
Faculty of Psychology and Education Sciences, University of Coimbra
Coimbra, Coimbra, Portugal, 300-115
About this study
Official title: Emotion Detectives - Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children: A Randomized Controlled Trial in the Portuguese Population
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) is a transdiagnostic and emotion-focused cognitive-behavioral group intervention for children aged 6-12 years old with emotion disorders (i.e., anxious and/or mood disorders) and their parents.
UP-C consists of 15 weekly group sessions and unifies cognitive-behavioral, contextual (e.g., mindfulness) and parental training techniques, for parents and children, aimed at reducing the intensity and frequency of strong and aversive emotional experiences in children and their clinical symptomatology.
Read more
The present study aims to assess the feasibility, acceptability and efficacy of the UP-C in the Portuguese population in reducing children's anxiety/depression symptoms. It also aims to investigate which mechanisms explain the therapeutic change.
Participants will be recruited at child mental health services and schools from Central Portugal and also through online dissemination of the study.
A randomized controlled trial (RCT) will be conducted in a sample of children aged 6-13 years old with emotional disorders and their parents in order to answer the critical question of whether the UP-C is more efficacious in reducing children's symptomatology than a psychoeducational group intervention (active control group).
Once the eligibility criteria are met (assessed by the project researchers) parents and children will be randomly assigned to one of two study conditions:
- experimental group (i.e., children and parents who benefit from the UP-C program).
- control group (i.e., children who benefit from a psychoeducational intervention program, named "ABC of Emotions").
Parents and children from both groups will complete several psychometrically robust and developmentally appropriate measures at baseline (T0), mid-treatment (only at week 7 of the UP-C; T1), post treatment (T2) and at 3 months follow-up (T3).
- Conditions
- Anxiety Disorders, Mood Disorders, Emotional Disorder, Emotional; Disorder, Childhood, With Anxiety and Fearfulness, Child Mental Disorder, Parenting
- Being tested
- Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C), ABC of Emotions
- Keywords
- emotional disorders, anxiety and mood disorders, children, parenting, transdiagnostic, unified protocol, randomized controlled trial
- Medical subject headings
- Anxiety Disorders, Mood Disorders, Neurodevelopmental Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C)Behavioural
Also called UP-C
UP-C is a transdiagnostic and emotion-focused cognitive-behavioral group intervention for children aged 6-13 years old with emotions disorders (i.e., anxious and/or mood disorders) and their parents. UP-C unifies cognitive-behavioral, contextual (eg. mindfulness) and parental training techniques aiming to reduce the intensity and frequency of children's clinical symptomatology.
The intervention consists of 15 weekly group sessions (90 minutes per session; 5-8 children and parents per group) conducted by at least two clinical psychologists trained in the UP-C. The sessions start with the parents and children together (15 minutes); then, one psychologist conduct the session with the group of children while the other psychologist conduct the session with the group of parents, simultaneously (60 minutes); finally, the session ends with the group together (15 minutes). This is a structured and manualized intervention with a manual for the therapist and a workbook for the child and parents.
ABC of EmotionsOther
ABC of Emotions is a psychoeducational group intervention for children with anxiety and/or mood disorders, aged between 6 to 13 years. ABC of Emotions consists of 5 group psychoeducation sessions (about 90 minutes per session; 5-8 children per group). This is a structured and manualized intervention, with a manual for the therapist and a workbook for the child.
The contents of the sessions were developed by the researchers of this study and are based on classic psychoeducational cognitive-behavioral therapies (CBT) strategies. Since anxiety disorders are more frequent in childhood than mood disorders (e.g., Merikangas et al., 2009), this program is essentially based on psychoeducation materials focused on emotions such as anxiety and fear. However, the same materials are available in an attachment, adapted for use with children to whom the main emotion is not fear/anxiety, but sadness (as in mood disorders).
| Study group | Role | What they receive |
|---|---|---|
| Experimental group (UP-C intervention) | Experimental | UP-C intervention 15 weekly sessions, for children and parents Receives: Behavioral: Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C) |
| Control group (ABC of emotions intervention) | Active comparator | ABC of emotions - a psychoeducational intervention 5 sessions every 3 weeks for children Receives: Other: ABC of Emotions |
What is being measured
The primary outcome is the main question the study is designed to answer.
Changes of children's anxiety and depression
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's severity of psychopathology and improvement
Measured with an adaptation of Clinical Global Impression (CGI). The CGI is composed by a severity of illness scale and a scale evaluating changes from the initiation of treatment. Higher scores are indicative of higher severity of psychopathology and lower improvement from the initiation of treatment.
Measured: Baseline, Póst treatment (15 weeks)
Secondary outcomes (17)
Changes of child anxiety life interference
Measured by Child Anxiety Life Interference Scale - self-report (CALIS-C) and parent's report (CALIS-P). The child form is composed by a single scale and the parent form is composed by two subscales (Child Interference Subscale and Family Interference Subscale). Higher scores are indicative of greater interference of anxiety symptoms in the life of the children and the family.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's psychological flexibility
Measured by The Avoidance and Fusion Questionnaire - Youth (AFQ-Y). AFQ-Y assess children's psychological inflexibility, namely children's experiential avoidance and cognitive fusion. Higher scores are indicative of higher levels of children's psychological inflexibility.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's behavioral avoidance
Measured by Child- and Parent-Report Measures of Behavioral Avoidance Related to Childhood Anxiety Disorders (CAMS and CAMP). Higher scores are indicative of higher levels of children's behavioral avoidance.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's negative affect
Measured by Positive and Negative Affect for Children (PANAS-C). PANAS-C is composed by two independent subscales: Positive Affect and Negative Affect. Higher scores are indicative of higher levels of children's positive and negative affect, respectively.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's negative emotionality
Measured by School-Age Temperament Inventory (SATI). It is composed by five dimensions: negative emotionality, inhibition, adaptability, activity, and persistence. Only the subscale of negative emotionality is used in this study. Higher scores are indicative of higher levels of negative emotionality.
Measured: Baseline, Póst-treatment (15 weeks)
Changes of children's anxiety sensitivity
Measured by Children's Anxiety Sensitivity Inventory-Revised (CASI-R). Higher scores are indicative of higher levels of anxiety sensitivity.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's tolerance of negative emotions
Measured by Distress Tolerance Scale (DTS). Higher scores are indicative of lower levels of tolerance to feel negative emotions.
Measured: Baseline, Mid-treatment (7 weeks), Póst treatment (15 weeks), Follow-up 3 months
Changes of children's mindfulness skills
Measured by The Child and Adolescent Mindfulness Measure (CAMM). Higher scores are indicative of higher levels of children's mindfulness skills.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's negative cognitive error
Measured by Children's Negative Cognitive Error Questionnaire (CNCEQ). It assesses four types of cognitive errors derived theoretically: catastrophizing, overgeneralization, personalizing, and selective abstraction. CNCEQ yields a Total Score for each type of cognitive error, a Total Score for areas of content (social, academic, Atlético) and a Total Score for cognitive errors. Higher values correspond to more cognitive errors.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's emotional expression and emotion awareness
Measured by Emotional Expression Scale for Children (EESC). Higher scores are indicative of higher levels of difficulties in children's emotional expression and emotion awareness.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of parent's anxiety and depression
Measured by Hospital Anxiety and Depression Scale (HADS). Higher scores are indicative of higher levels of anxiety and depression.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks)
Changes of parental anxiety, parental overprotection and parental support of children's coping behaviors
Measured by Parental anxiety and overprotection scale (PAOS). Higher scores are indicative of higher levels of parental anxiety, parental overprotection and parental support of children's coping behaviors.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of parental neuroticism
Measured by NEO Five-Factor Inventory (NEO-FFI). It assesses the five traits of personality defined in the Five Factor Theory of Personality: Openness, Conscientiousness, Extraversion, Agreeableness and Neuroticism. In the present study only Neuroticism subscale was used. Higher scores are indicative of higher levels of neuroticism.
Measured: Baseline, Póst-treatment (15 weeks)
Changes of parental inconsistency and permissiveness
Measured by Parenting Styles \& Dimensions Questionnaire. Only the permissiveness subscale was used with higher scores being indicative of higher levels of parental inconsistency and permissiveness.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of parental criticism
Measured by EMBU-P (egna minnen beträffande uppfostran). It assesses four dimensions: emotional support, rejection, control attempt and sibling preference. In this study, only the rejection subscale was used, which assesses parental rejection and criticism. Higher scores indicate higher levels of rejection and parental criticism.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of shaping of negative emotions
Measured by The Parent Emotion Regulation Scale (PERS). It assesses four dimensions: parents' orientation to the child's emotions, parents' avoidance of the child's emotions, parents' lack of emotional control and parents' acceptance of the child's and their own emotions. In the present study only parents' lack of emotional control scale was used. This subscale assesses the lack of ability to modulate their own negative emotions in the presence of the child. Higher scores are indicative of higher levels of shaping of negative emotions.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of mindfulness in parenting
Measured by Interpersonal Mindfulness in Parenting Scale (IMP). Higher scores are indicative of higher levels of mindfulness in parenting.
Measured: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Jun 2021
- Study start1 Mar 2021
- Primary completion30 Aug 2022
- Study completion30 Nov 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Anxiety DisordersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- 1. experimental group (i.e., children and parents who benefit from the UP-C program). 2. control group (i.e., children who benefit from a psychoeducational intervention program, named "ABC of Emotions").
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 153 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Coimbra
- Sponsor type
- University, hospital or other
- Collaborators
- Fundação para a Ciência e a Tecnologia, Centro Hospitalar Tondela-Viseu
- Responsible party
- Principal investigator, Brigida Caiado, University of Coimbra
- Investigators
- Brígida Caiado, MsC, Principal investigator, Faculty of Psychology and Education Sciences, University of Coimbra
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04932421
- Sponsor's protocol ID
- Univeristy of Coimbra
- Acronym
- UP-C
- Status last verified
- Oct 2023
- First submitted
- 31 May 2021
- Last updated
- 12 Oct 2023
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Caiado B, Gois A, Pereira B, Canavarro MC, Moreira H. The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) in Portugal: Feasibility Study Results. Int J Environ Res Public Health. 2022 Feb 4;19(3):1782. doi: 10.3390/ijerph19031782.
PubMed 35162806
Study at a glance
From the registry record, last updated by the sponsor on 12 Oct 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Emotion Detectives - Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children: A Randomized Controlled Trial in the Portuguese Population
- ClinicalTrials.gov ID
- NCT04932421
- Acronym / sponsor ID
- UP-C / Univeristy of Coimbra
- Conditions
- Anxiety Disorders, Mood Disorders, Emotional Disorder, Emotional; Disorder, Childhood, With Anxiety and Fearfulness, Child Mental Disorder, Parenting
- Keywords
- emotional disorders, anxiety and mood disorders, children, parenting, transdiagnostic, unified protocol, randomized controlled trial
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 153 participants (actual)
- Lead sponsor
- University of CoimbraUniversity, hospital or other
- Collaborators
- Fundação para a Ciência e a Tecnologia, Centro Hospitalar Tondela-Viseu
- Study start
- 1 Mar 2021 (actual)
- Primary completion
- 30 Aug 2022 (actual)
- Study completion
- 30 Nov 2022 (actual)
- First posted
- 21 Jun 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) is a transdiagnostic and emotion-focused cognitive-behavioral group intervention for children aged 6-12 years old with emotion disorders (i.e., anxious and/or mood disorders) and their parents.
UP-C consists of 15 weekly group sessions and unifies cognitive-behavioral, contextual (e.g., mindfulness) and parental training techniques, for parents and children, aimed at reducing the intensity and frequency of strong and aversive emotional experiences in children and their clinical symptomatology.
The present study aims to assess the feasibility, acceptability and efficacy of the UP-C in the Portuguese population in reducing children's anxiety/depression symptoms. It also aims to investigate which mechanisms explain the therapeutic change.
Participants will be recruited at child mental health services and schools from Central Portugal and also through online dissemination of the study.
A randomized controlled trial (RCT) will be conducted in a sample of children aged 6-13 years old with emotional disorders and their parents in order to answer the critical question of whether the UP-C is more efficacious in reducing children's symptomatology than a psychoeducational group intervention (active control group).
Once the eligibility criteria are met (assessed by the project researchers) parents and children will be randomly assigned to one of two study conditions:
- experimental group (i.e., children and parents who benefit from the UP-C program).
- control group (i.e., children who benefit from a psychoeducational intervention program, named "ABC of Emotions").
Parents and children from both groups will complete several psychometrically robust and developmentally appropriate measures at baseline (T0), mid-treatment (only at week 7 of the UP-C; T1), post treatment (T2) and at 3 months follow-up (T3).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
- Model description
- 1. experimental group (i.e., children and parents who benefit from the UP-C program). 2. control group (i.e., children who benefit from a psychoeducational intervention program, named "ABC of Emotions").
| Arm | Type | Receives |
|---|---|---|
| Experimental group (UP-C intervention) | Experimental | Behavioral: Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C)UP-C intervention 15 weekly sessions, for children and parents |
| Control group (ABC of emotions intervention) | Active comparator | Other: ABC of EmotionsABC of emotions - a psychoeducational intervention 5 sessions every 3 weeks for children |
Who may qualify
- Ages
- 6 to 13 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (3 listed)
- Children aged 6-13
- Primary diagnosis of an anxiety and/or depression disorder
- Speaking, reading and understanding Portuguese
Key exclusion criteria (3 listed)
- Diagnosis of a psychotic disorder, bipolar disorder or intellectual disability;
- Severe current suicidal/homicidal ideation;
- The child is not on a stable dose of a psychotropic or other type of medication for at least 1 month prior to T0 assessment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C)Also: UP-CUP-C is a transdiagnostic and emotion-focused cognitive-behavioral group intervention for children aged 6-13 years old with emotions disorders (i.e., anxious and/or mood disorders) and their parents. UP-C unifies cognitive-behavioral, contextual (eg. mindfulness) and parental training techniques aiming to reduce the intensity and frequency of children's clinical symptomatology. The intervention consists of 15 weekly group sessions (90 minutes per session; 5-8 children and parents per group) conducted by at least two clinical psychologists trained in the UP-C. The sessions start with the parents and children together (15 minutes); then, one psychologist conduct the session with the group of children while the other psychologist conduct the session with the group of parents, simultaneously (60 minutes); finally, the session ends with the group together (15 minutes). This is a structured and manualized intervention with a manual for the therapist and a workbook for the child and parents. | Behavioural | Experimental group (UP-C intervention) |
| ABC of EmotionsABC of Emotions is a psychoeducational group intervention for children with anxiety and/or mood disorders, aged between 6 to 13 years. ABC of Emotions consists of 5 group psychoeducation sessions (about 90 minutes per session; 5-8 children per group). This is a structured and manualized intervention, with a manual for the therapist and a workbook for the child. The contents of the sessions were developed by the researchers of this study and are based on classic psychoeducational cognitive-behavioral therapies (CBT) strategies. Since anxiety disorders are more frequent in childhood than mood disorders (e.g., Merikangas et al., 2009), this program is essentially based on psychoeducation materials focused on emotions such as anxiety and fear. However, the same materials are available in an attachment, adapted for use with children to whom the main emotion is not fear/anxiety, but sadness (as in mood disorders). | Other | Control group (ABC of emotions intervention) |
Primary outcome
Changes of children's anxiety and depression
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's severity of psychopathology and improvement
Time frame: Baseline, Póst treatment (15 weeks)
Measured with an adaptation of Clinical Global Impression (CGI). The CGI is composed by a severity of illness scale and a scale evaluating changes from the initiation of treatment. Higher scores are indicative of higher severity of psychopathology and lower improvement from the initiation of treatment.
17 secondary outcomes
Changes of child anxiety life interference
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's psychological flexibility
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's behavioral avoidance
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's negative affect
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's negative emotionality
Time frame: Baseline, Póst-treatment (15 weeks)
Changes of children's anxiety sensitivity
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's tolerance of negative emotions
Time frame: Baseline, Mid-treatment (7 weeks), Póst treatment (15 weeks), Follow-up 3 months
Changes of children's mindfulness skills
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's negative cognitive error
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of children's emotional expression and emotion awareness
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of parent's anxiety and depression
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks)
Changes of parental anxiety, parental overprotection and parental support of children's coping behaviors
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of parental neuroticism
Time frame: Baseline, Póst-treatment (15 weeks)
Changes of parental inconsistency and permissiveness
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of parental criticism
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of shaping of negative emotions
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Changes of mindfulness in parenting
Time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Oct 2023.
- Results publication: PubMed 35162806Caiado B, Gois A, Pereira B, Canavarro MC, Moreira H. The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) in Portugal: Feasibility Study Results. Int J Environ Res Public Health. 2022 Feb 4;19(3):1782. doi: 10.3390/ijerph19031782.
- Project webisteLink provided by the sponsor.
- Project facebookLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Brígida Caiado, MsC principal investigator
Faculty of Psychology and Education Sciences, University of Coimbra
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C) and ABC of Emotions in people with Anxiety Disorders and Mood Disorders, run by University of Coimbra at 1 site in Portugal.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Oct 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Portugal. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Changes of children's anxiety and depression (time frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04932421, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Oct 2023; AzTrials last refreshed its copy on 30 Oct 2026.