Kidney StoneNCT04937192
SNP-based Prediction of Recurrence Risk in Kidney Stone Patients
An observational study of Kidney Stone, run by The First Affiliated Hospital of Guangzhou Medical University at 1 site in China.
Trial summary
The goal of this study is to gain new knowledge about genetic risk factors that may affect the kidney stone recurrence. The study seeks to understand if different forms of genes result in an increased risk of kidney stone recurrence. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Kidney Stone
- How many people
- 1,300 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2012to 31 Dec 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Kidney stone former who the stone was removed completely
Who may be able to join
- Age 18 or older
- Kidney stone former who the stone was removed completely.
- Ability to give informed consent
Who cannot join
- Patient refuses or is unable to give consent
Trial locations and contacts
1 site in 1 country.
China1 site, 1 recruiting
- Recruiting
The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, 510120
Guohua Zeng, Ph.D., +86 13802916676, gzgyzgh@vip.sina.com
Guohua Zeng, M.D.
About this study
Official title: SNP-based Prediction of Recurrence Risk in Kidney Stone Patients: a Prospective Multicenter Observational Study
The goal of this study is to gain new knowledge about genetic risk factors that may affect the kidney stone recurrence. The study seeks to understand if different forms of genes result in an increased risk of kidney stone recurrence.
Read the detailed description
In this study, investigators are prospectively testing whether SNP are associated with kidney stone recurrence. Investigators will test the hypothesis that SNP predispose kidney stone patients to recurrence.
Investigators hope to identify predictors for the kidney stone recurrence. This would allow the identification of a subpopulation of kidney stone patients that would benefit most from prevention measures.
- Conditions
- Kidney Stone
- Being tested
- No intervention
- Keywords
- SNP, Kidney stone, Recurrence
- Medical subject headings
- Kidney Calculi, Recurrence
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No interventionOther
No intervention
| Study group | Role | What they receive |
|---|---|---|
| Kidney stone former | Not described Receives: Other: No intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Stone-free survival
Time to first stone recurrence from stone-free
Measured: From date of stone-free until the date of first stone recurrence (up to 7 years)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jun 2021
- Study start1 Jan 2012
- Primary completion31 Dec 2022 (estimated)
- Study completion31 Dec 2023 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Kidney StoneStudies of the same condition, open and under way.
- More trials run by The First Affiliated Hospital of Guangzhou Medical UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,300 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Collaborators
- Xiangya Hospital of Central South University, Wuhan University Renmin Hospital, The Second Affiliated Hospital of Kunming Medical University, Tianjin Medical University Second Hospital, Shenzhen People's Hospital, Chinese PLA General Hospital, Zhongda Hospital, People's Hospital of Xinjiang, ZhuZhou Central Hospital, Yunnan Baoshan Second People's Hospital, Guangdong No.2 People's Hospital, Dehong People's Hospital, Second Affiliated Hospital of Guangzhou Medical University, Jiangmen Central Hospital, Huizhou Municipal Central Hospital, Yongzhou Center Hospital, Longgang District People's Hospital of Shenzhen
- Responsible party
- Principal investigator, Guohua Zeng, The First Affiliated Hospital of Guangzhou Medical University
- Investigators
- Guohua Zeng, M.D., Principal investigator, The First Affiliated Hospital of Guangzhou Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04937192
- Sponsor's protocol ID
- MRER2013-001
- Status last verified
- Oct 2022
- First submitted
- 10 Jun 2021
- Last updated
- 25 Oct 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 25 Oct 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- SNP-based Prediction of Recurrence Risk in Kidney Stone Patients: a Prospective Multicenter Observational Study
- ClinicalTrials.gov ID
- NCT04937192
- Acronym / sponsor ID
- MRER2013-001
- Conditions
- Kidney Stone
- Keywords
- SNP, Kidney stone, Recurrence
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 1,300 participants (estimated)
- Lead sponsor
- The First Affiliated Hospital of Guangzhou Medical UniversityUniversity, hospital or other
- Collaborators
- Xiangya Hospital of Central South University, Wuhan University Renmin Hospital, The Second Affiliated Hospital of Kunming Medical University, Tianjin Medical University Second Hospital, Shenzhen People's Hospital, Chinese PLA General Hospital, Zhongda Hospital, People's Hospital of Xinjiang, ZhuZhou Central Hospital, Yunnan Baoshan Second People's Hospital, Guangdong No.2 People's Hospital, Dehong People's Hospital, Second Affiliated Hospital of Guangzhou Medical University, Jiangmen Central Hospital, Huizhou Municipal Central Hospital, Yongzhou Center Hospital, Longgang District People's Hospital of Shenzhen
- Study start
- 1 Jan 2012 (actual)
- Primary completion
- 31 Dec 2022 (estimated)
- Study completion
- 31 Dec 2023 (estimated)
- First posted
- 23 Jun 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to gain new knowledge about genetic risk factors that may affect the kidney stone recurrence. The study seeks to understand if different forms of genes result in an increased risk of kidney stone recurrence.
Detailed description
In this study, investigators are prospectively testing whether SNP are associated with kidney stone recurrence. Investigators will test the hypothesis that SNP predispose kidney stone patients to recurrence.
Investigators hope to identify predictors for the kidney stone recurrence. This would allow the identification of a subpopulation of kidney stone patients that would benefit most from prevention measures.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Kidney stone former | – | Other: No intervention |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Kidney stone former who the stone was removed completely
Key inclusion criteria (3 listed)
- Age 18 or older
- Kidney stone former who the stone was removed completely.
- Ability to give informed consent
Key exclusion criteria (1 listed)
- Patient refuses or is unable to give consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No interventionNo intervention | Other | Kidney stone former |
Primary outcome
Stone-free survival
Time frame: From date of stone-free until the date of first stone recurrence (up to 7 years)
Time to first stone recurrence from stone-free
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Oct 2022.
- Individual participant dataSharing planned: Undecided
Related trials for Kidney Stone
Not yet recruiting
Automated Versus Manual Irrigation During Flexible Ureteroscopy
Renal Stone Disease
Not yet recruiting
Optimal Intrarenal Pressure During Flexible Ureteroscopy
Renal Stone Disease
RecruitingObservational study
Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence Study
Urolithiasis, Stones, Kidney
Not yet recruiting
Intertransverse Process Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Percutaneous Nephrolithotomy
Kidney Stones, Urolithiasis, Hypocitraturia, Pain, Postoperative
Not yet recruiting
Comparison of Smart Pressure-Controlled Flexible Ureteroscopy and Flexible Suction Ureteral Access Sheath-Assisted Flexible Ureteroscopy for 2-3 cm Renal Stones
Kidney Stones
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Guohua Zeng, M.D. principal investigator
The First Affiliated Hospital of Guangzhou Medical University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Kidney Stone, run by The First Affiliated Hospital of Guangzhou Medical University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 25 Oct 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Guohua Zeng, M.D. (13802916676, gzgyzgh@vip.sina.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Stone-free survival (time frame: From date of stone-free until the date of first stone recurrence (up to 7 years)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Oct 2022.