Clinical trials: Kidney Stone
Kidney Stone, Benign Prostatic Hyperplasia
Utilization of a Web-Based Application to Improve Patient Health Literacy and Reduce Clinic Visit Times in Holmium Laser Enucleation of the Prostate (HoLEP) Procedures and Kidney Stone Surgery
The investigator and research team plan to investigate whether patients who receive access to WellPrept website will report greater confidence and understanding of their medical condition, have shorter clinic visit times, and…
- Trial name
- NCT07580391
- Testing
- WellPrept, Standard Care
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Urolithiasis
Urine and Stool Analysis in Kidney Stone Disease
The purpose of this study is to add to the investigators' quest to understanding stone disease, by evaluating the metabolites excretion in urine and its relation to microflora present in the stool.
- Trial name
- NCT01637506
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Calcium Phosphate Kidney Stones
Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones
This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.
- Trial name
- NCT06003348
- Testing
- OHCit- standard dose, Potassium Citrate, OHCit- low dose
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Calculi, Crohn's Disease
Calcium Supplements Strategy for Kidney Stones Prevention in Crohn's Patients
Hospitalization for kidney stones in the Inflammatory Bowel Disease (IBD) population is common, particularly among Crohn's patients who had a small bowel resection.
- Trial name
- NCT01735461
- Testing
- Calcium Carbonate
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Healthy, Enteric Hyperoxaluria
Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2).
- Trial name
- NCT05650112
- Testing
- FB-001
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federation Bio Inc.
Bariatric Surgery Candidate, Kidney Stone
GI Oxalate Absorption
This study aims to learn more about how oxalate, a compound found in many foods, may affect a person's chances of forming kidney stones. Active participation in this study will last for around one week.
- Trial name
- NCT05356000
- Testing
- Special low-oxalate diet followed by all-day visit to University of Chicago research clinic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Stone, Kidney, Urolithiasis
Staged Bilateral Percutaneous Nephrolithotomy
To determine the optimal time between the first and second operations in patients with bilateral kidney stones and scheduled percutaneous nephrolithotomy for the contralateral kidney.
- Trial name
- NCT05340075
- Testing
- Patients who underwent percutaneous nephrolithotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Training and Research Hospital
Determine the Efficacy and Safety of SWL in Renal Stones Larger Than 2 cm in Pediatric Age Group
Extracorporeal Shock Wave Lithotripsy for Treatment of Large Pediatric Renal Pelvic Stone Burden More Than 2 cm
Extracorporeal shock wave lithotripsy (SWL) was first described for pediatric nephrolithiasis in 1986; SWL has been a mainstay of treatment for both renal and ureteral calculi in children .
- Trial name
- NCT05293613
- Testing
- extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pain, Urinary Stone
Prospective Randomized Controlled Trial for Pain Relief After Office Ureteral Stent Removal
This is a prospective randomized double-blind controlled trial assessing the benefits of intramuscular ketorolac before or immediately after office ureteral stent removal.
- Conditions
- Pain, Urinary Stone, Urinary Calculi
- Trial name
- NCT04112160
- Testing
- Ketorolac, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Stones
Comparison of RIRS Versus PCNL Methods, According to Postoperative Pain and Analgesic Demand in 2 to 4 cm Renal Stones
Purpose: to investigate the postoperative outcomes of Retrograde intrarenal surgery versus percutaneous nephrolithotomy in 2 to 4 cm kidney stones.
- Trial name
- NCT02430168
- Testing
- Percutaneous nephrolithotomy, Retrograde intrarenal surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Diskapi Teaching and Research Hospital
Kidney Stones, Ureteral Stones
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
To determine if emergency department patients with acute ureteral colic pain due to a ureteral stone who are treated with tamsulosin, versus placebo, will experience a shorter time to passage of their stone or resolution of their…
- Trial name
- NCT00448123
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Robert Swor
Ureteral Stones, Kidney Stones
Trial Comparing Relapse Rates Between Standard Ureteroscopic Removal Of Ureteral Stone And Standard Removal With Additional Ureterorenic Clearing Of Non-Symptomatic Stones In The Kidney
Patients with a ureteral or kidney stone that causes symptoms, like pain, frequently have small kidney stones that don't cause symptoms.
- Trial name
- NCT02210650
- Testing
- Symptomatic stone removal, Asymptomatic kidney stones and ureteral stone removed
- Where
- 4 sites in United States
- Volunteers
- 75 people
- Sponsor
- Indiana Kidney Stone Institute
Nephrolithiasis, Postoperative Pain
Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure used to remove large or complex kidney stones. Although effective, dilation of the surgical tract and the placement of a nephrostomy tube cause…
- Conditions
- Nephrolithiasis, Postoperative Pain, Quality of Recovery
- Trial name
- NCT07855068
- Testing
- Ketamine and Dexmedetomidine, Fentanyl
- Volunteers
- 100 people
- Sponsor
- Assiut University
Urolithiasis
Effect of Ureteral Access Sheath Use on Postoperative Pain Level in Patients Undergoing RIRS
This study will include patients aged between 18 and 70 who will undergo retrograde intrarenal surgery (RIRS) due to renal stone(s).
- Trial name
- NCT02501525
- Testing
- RIRS with ureteral access sheath, RIRS without ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Selcuk University
Nephrolithiasis, Uric Acid
Pathogenesis of Uric Acid Nephrolithiasis: Role of Pioglitazone/Weight Loss
The investigators will randomize overweight and obese iuan patients to Pio (45 mg/day, highest approved dose or placebo), WL (10% of body weight, following the established program used in the Diabetes Prevention Program), or…
- Trial name
- NCT04370093
- Testing
- Pioglitazone 45 mg, Weight Loss, Pioglitazone + Weight Loss
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Stone, Nephrolithiasis
Prediction of Recurrence and Complications of Nephrolithiasis Using a Precision Medicine Approach
Nephrolithiasis is a disease caused by the formation of kidney stones in the urinary tract which can then partially or completely obstruct the latter causing an extremely sharp pain called renal colic.
- Trial name
- PRECILITH (NCT05237063)
- Testing
- Blood and urine samples
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Surgery-Complications, Nephrolithiasis Staghorn Calculus
Comparison of Total Tubeless Mini-PCNL Versus Tubeless Mini-PCNL
Limited literature has focused on the use of totally tubeless mini-percutaneous nephrolithotomy (Mini-PCNL) for the treatment of large renal stones.
- Conditions
- Surgery-Complications, Nephrolithiasis Staghorn Calculus, Safety Issues
- Trial name
- NCT06288022
- Testing
- total tubeless mini-PCNL, tubeless mini-PCNL
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Pain Management, Extracorporeal Shock Wave Lithotripsy
The Effect Of Virtual Reality Glasses On Pain And Anxiety During The Kidney Stone Lithotripsy Procedure
To determine the pain and anxiety levels of patients using virtual reality glasses during the extracorporeal shock wave lithotripsy procedure.
- Conditions
- Pain Management, Extracorporeal Shock Wave Lithotripsy, Virtual Reality
- Trial name
- NCT06629727
- Testing
- VR Group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Beykent
Kidney Neoplasm, Kidney Stone
A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members
Approximately 30,000 new patients are introduced into dialysis and about 20,000 of them die every year in Japan. At present, about 300,000 patients are on dialysis and more than 10,000 patients are registered with the Japan Organ…
- Conditions
- Kidney Neoplasm, Kidney Stone, Ureteral Tumor, Ureteral Stricture
- Trial name
- NCT00994188
- Testing
- Restored Kidney Transplant Between Family Members
- Where
- 2 sites in Japan
- Volunteers
- 5 people
- Sponsor
- Tokushukai Medical Group
Kidney Stones, Nephrolithiasis
Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery
This randomized clinical trial will compare four ventilation strategies during retrograde intrarenal surgery performed under general anesthesia.
- Trial name
- RIRS-VENT (NCT07705646)
- Testing
- Standard Ventilation, Hypoventilation, Intermittent Apnea Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey