GaitB670201942108NCT04987346
Normative Database for Gait Analysis on the GRAIL UZ Gent
A study testing Walking on an instrumented treadmill and Walking on an instrumented treadmill while dual-tasking in people with Gait, run by University Hospital, Ghent at 1 site in Belgium.
Trial summary
The aim of this study is to collect a large set of norm/control data on an instrumented treadmill (the Gait Real-time Analysis Interactive Lab - GRAIL) at the university hospital of Ghent for the purpose of clinical studies as well as for clinical interpretation. Read more about this study
- Who is it for?
- Ages 6 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Gait
- What is being tested?
- Walking on an instrumented treadmill and Walking on an instrumented treadmill while dual-tasking
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 240 participants
- Where
- 1 siteBelgium
- Study dates
- 14 Jul 2021to 1 Jan 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 65 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Healthy participants
Who cannot join
- They suffer from neurological disorder
- Have balance problems
- Take medications that affect gait and balance
- Have undergone surgical procedures on the lower limbs in the past
- Experience pain in their lower limbs or back at the time of test taking.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Belgium1 site, 1 recruiting
- Recruiting
Ghent University Hospital
Ghent, 9000
Anke Van Bladel, anke.vanbladel@uzgent.be
About this study
Official title: Normative Database for Gait Analyses and Balance on the GRAIL at the University Hospital of Ghent.
The aim of this study is to collect a large set of norm/control data on an instrumented treadmill (the Gait Real-time Analysis Interactive Lab - GRAIL) at the university hospital of Ghent for the purpose of clinical studies as well as for clinical interpretation.
We hypothesize that this norm/control data will provide reference data of the normal gait patterns in the healthy population such that we can then use it to identify gait abnormalities in populations with pathology.
Read more
The following data will be collected on the GRAIL while subjects walk at different gait speeds: 3D kinematics, kinetics, and EMG.
Additionally, 3D kinematics, kinetics, and EMG data will be collected when performing either a cognitive (Stroop Color and Word Test) or motor (requiring arm swing) dual-task while walking at comfortable walking speed.
- Conditions
- Gait
- Being tested
- Walking on an instrumented treadmill, Walking on an instrumented treadmill while dual-tasking
- Keywords
- Gait analysis, Control group, Healthy, Reference data, Kinematics, Kinetics, EMG, Dual-tasking
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Walking on an instrumented treadmillOther
Participants will be asked to walk at different gait velocities for 1 minute. The treadmill speed will be increased incrementally at 0.1m/s intervals until just before running.
Walking on an instrumented treadmill while dual-taskingOther
Participants aged between 6 and 17 years will be asked to walk at comfortable walking speed while playing either a cognitive (Stroop Color and Word Test) or motor (requiring arm swing) game.
| Study group | Role | What they receive |
|---|---|---|
| Treadmill walking | Experimental | Participants will be asked to walk at different gait velocities for 1 minute. The treadmill speed will be increased incrementally at 0.1m/s intervals until just before running. Receives: Other: Walking on an instrumented treadmill; Other: Walking on an instrumented treadmill while dual-tasking |
What is being measured
The primary outcome is the main question the study is designed to answer.
Kinematics
3D kinematics of lower and upper limb joints while walking (degrees)
Measured: single point assessment in 1 day
Kinetics
3D kinetics of lower limb joints while walking (Nm)
Measured: single point assessment in 1 day
EMG
Muscle activity of 32 lower and upper limb muscles (micorvolts)
Measured: single point assessment in 1 day
EMG synergies
Synergy analysis will be carried using the EMG data (variance accounted for -VAF)
Measured: single point assessment in 1 day
Spatiotemporal parameters
Spatial parameters (m)
Measured: single point assessment in 1 day
Spatiotemporal parameters
Temporal parameters (s)
Measured: single point assessment in 1 day
Spatiotemporal parameters
Walking velocity (m/s)
Measured: single point assessment in 1 day
Secondary outcomes (3)
Gait deviation index
Based on kinematics, the lower-limb gait deviations will be calculated (degrees)
Measured: single point assessment in 1 day
Game result (cognitive task)
Score (% correct)
Measured: single point assessment in 1 day
Game result (motor task)
Score (% correct)
Measured: single point assessment in 1 day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Aug 2021
- Study start14 Jul 2021
- Primary completion1 Jan 2029 (estimated)
- Study completion1 Jan 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for GaitStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 240 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Ghent
- Sponsor type
- University, hospital or other
- Collaborators
- University Ghent
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04987346
- Sponsor's protocol ID
- BC-06520
- Acronym
- B670201942108
- Status last verified
- Sep 2026
- First submitted
- 5 Jul 2021
- Last updated
- 21 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Normative Database for Gait Analyses and Balance on the GRAIL at the University Hospital of Ghent.
- ClinicalTrials.gov ID
- NCT04987346
- Acronym / sponsor ID
- B670201942108 / BC-06520
- Conditions
- Gait
- Keywords
- Gait analysis, Control group, Healthy, Reference data, Kinematics, Kinetics, EMG, Dual-tasking
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 240 participants (estimated)
- Lead sponsor
- University Hospital, GhentUniversity, hospital or other
- Collaborators
- University Ghent
- Study start
- 14 Jul 2021 (actual)
- Primary completion
- 1 Jan 2029 (estimated)
- Study completion
- 1 Jan 2029 (estimated)
- First posted
- 3 Aug 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to collect a large set of norm/control data on an instrumented treadmill (the Gait Real-time Analysis Interactive Lab - GRAIL) at the university hospital of Ghent for the purpose of clinical studies as well as for clinical interpretation.
We hypothesize that this norm/control data will provide reference data of the normal gait patterns in the healthy population such that we can then use it to identify gait abnormalities in populations with pathology.
The following data will be collected on the GRAIL while subjects walk at different gait speeds: 3D kinematics, kinetics, and EMG.
Additionally, 3D kinematics, kinetics, and EMG data will be collected when performing either a cognitive (Stroop Color and Word Test) or motor (requiring arm swing) dual-task while walking at comfortable walking speed.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Treadmill walking | Experimental | Other: Walking on an instrumented treadmill, Other: Walking on an instrumented treadmill while dual-taskingParticipants will be asked to walk at different gait velocities for 1 minute. The treadmill speed will be increased incrementally at 0.1m/s intervals until just before running. |
Who may qualify
- Ages
- 6 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (1 listed)
- Healthy participants
Key exclusion criteria (5 listed)
- They suffer from neurological disorder
- Have balance problems
- Take medications that affect gait and balance
- Have undergone surgical procedures on the lower limbs in the past
- Experience pain in their lower limbs or back at the time of test taking.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Walking on an instrumented treadmillParticipants will be asked to walk at different gait velocities for 1 minute. The treadmill speed will be increased incrementally at 0.1m/s intervals until just before running. | Other | Treadmill walking |
| Walking on an instrumented treadmill while dual-taskingParticipants aged between 6 and 17 years will be asked to walk at comfortable walking speed while playing either a cognitive (Stroop Color and Word Test) or motor (requiring arm swing) game. | Other | Treadmill walking |
Primary outcome
Kinematics
Time frame: single point assessment in 1 day
3D kinematics of lower and upper limb joints while walking (degrees)
Kinetics
Time frame: single point assessment in 1 day
3D kinetics of lower limb joints while walking (Nm)
EMG
Time frame: single point assessment in 1 day
Muscle activity of 32 lower and upper limb muscles (micorvolts)
EMG synergies
Time frame: single point assessment in 1 day
Synergy analysis will be carried using the EMG data (variance accounted for -VAF)
Spatiotemporal parameters
Time frame: single point assessment in 1 day
Spatial parameters (m)
Spatiotemporal parameters
Time frame: single point assessment in 1 day
Temporal parameters (s)
Spatiotemporal parameters
Time frame: single point assessment in 1 day
Walking velocity (m/s)
3 secondary outcomes
Gait deviation index
Time frame: single point assessment in 1 day
Game result (cognitive task)
Time frame: single point assessment in 1 day
Game result (motor task)
Time frame: single point assessment in 1 day
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Walking on an instrumented treadmill and Walking on an instrumented treadmill while dual-tasking in people with Gait, run by University Hospital, Ghent at 1 site in Belgium.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 21 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Belgium. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Anke Van Bladel, PhD (093321243, Anke.VanBladel@UGent.be), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Kinematics (time frame: single point assessment in 1 day). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Sep 2026.