Trigger FingerSECOIANCT05045157
Effectiveness of Percutaneous Pulley Release With Infiltration, Versus Infiltration Alone in Trigger Finders
A study testing Percutaneous A1 Pulley Release Under Ultrasound Guidance and Corticosteroid injection in people with Trigger Finger, run by Centre Hospitalier Departemental Vendee at 4 sites in France.
Trial summary
Trigger finger is a mechanical problem characterized by pain and catching of digit in flexion. Histological changes of A1 pulley and synovial proliferation have been identified as factors that prompt trigger finger The first-line treatment of trigger finger is conservative with splinting and corticosteroid injection. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Trigger Finger
- What is being tested?
- Percutaneous A1 Pulley Release Under Ultrasound Guidance and Corticosteroid injection
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 4 sitesFrance
- Study dates
- 31 May 2022to 31 May 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patient ≥ 18 years old,
- Presence of a trigger finger (thumb or long fingers) to be treated
- Quinnell score >1
- Episode of trigger characterized on questioning or clinical examination
- Failure of a first corticosteroid infiltration > 3 months before inclusion
- First infiltration within 15 months of inclusion
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- Thickening A1 pulley on ultrasound ≥ 0.5 mm
- Patient who has the capacity to understand the protocol and has given consent to participate in the research,
- Patient with social security coverage
Who cannot join
- Presence of several symptomatic fingers requiring treatment by ultrasound-guided section of the pulley
- Patient who are pregnant, breastfeeding, or who have the potential to become pregnant without effective contraception at the time of inclusion
- Known allergy to corticoid (Hydrocortancyl®) including its excipients ((benzyl alcohol, sodium carmellose, sodium chloride, polysorbate 80)
- Known allergies to lidocaine
- Ongoing anticoagulant treatments (AVK, New Oral Anti-Coagulants)
- Local or general infection, or suspicion of infection
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- Live vaccines
- Evolving viruses (hepatitis, herpes, varicella, shingles)
- Severe or uncontrolled hypertension
- Unbalanced diabetes
- Underlying progressive cardiovascular disease
- Hemodialysis patients
- Prosthesis on the finger to be treated
- Echographic tendon fissure
- Inflammatory disease (rheumatoid arthritis, spondyloarthritis, connective tissue diseases, etc.) with tenosynovitis.
- History of surgery on the fingers
- Dupuytren's disease
- Patient participating in another interventional clinical research protocol involving a drug or medical device
- Patient under guardianship, curators or legal protection
Trial locations and contacts
4 sites in 1 country.
France4 sites
Hopital Henri Mondor
Créteil, 94000
CHD Vendée
La Roche-sur-Yon, 85925
CHU Nantes
Nantes, 44000
Hopital Lariboisière
Paris, 75010
About this study
Official title: Effectiveness of Percutaneous A1 Pulley Release Under Ultrasound Guidance Associated With Infiltration, Versus Infiltration Alone, in Patients With Trigger Finders Who Have Failed a First Infiltration: a Randomized Controlled Trial
Trigger finger is a mechanical problem characterized by pain and catching of digit in flexion.
Histological changes of A1 pulley and synovial proliferation have been identified as factors that prompt trigger finger The first-line treatment of trigger finger is conservative with splinting and corticosteroid injection.
Read more
If the first infiltration fails, either a second infiltration or surgical sectioning of the pulley is proposed.
Surgery can be performed by several techniques (open section, percutaneous section with palpatory guidance, or under ultrasound guidance).
Percutaneous A1 pulley release under ultrasound guidance consists of cutting the A1 pulley by a percutaneous insertion with small needle under local anaesthesia.
The hypothesis of the study is that percutaneous A1 pulley release under ultrasound guidance followed by a corticosteroid injection would be more effective than a second corticosteroid injection alone on complete resolution of the trigger finger symptoms
- Conditions
- Trigger Finger
- Being tested
- Percutaneous A1 Pulley Release Under Ultrasound Guidance, Corticosteroid injection
- Medical subject headings
- Trigger Finger Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Percutaneous A1 Pulley Release Under Ultrasound GuidanceProcedure or surgery
the A1 pulley is cut off with Ultrasound guidance by a percutaneous insertion of the small needle under local anaesthesia.
Corticosteroid injectionDrug
corticosteroid injection is performed
| Study group | Role | What they receive |
|---|---|---|
| percutaneous A1 pulley release with corticosteroid injection | Experimental | Not described Receives: Procedure: Percutaneous A1 Pulley Release Under Ultrasound Guidance; Drug: Corticosteroid injection |
| corticosteroid injection alone | Active comparator | Not described Receives: Drug: Corticosteroid injection |
What is being measured
The primary outcome is the main question the study is designed to answer.
Effectiveness of pulley section with ultrasound guidance combined with corticosteroid infiltration versus corticosteroid alone on complete resolution of trigger finger's symptoms
Trigger finger's symptoms defined by a clinical Quinnell score ≤1 without the use of an alternative therapy
Measured: 1 year postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Sep 2021
- Study start31 May 2022
- Primary completion31 May 2026
- Study completion31 May 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Trigger FingerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Departemental Vendee
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Grégoire Cormier, Dr, Principal investigator, CHD Vendée
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05045157
- Sponsor's protocol ID
- CHD21_0024
- Acronym
- SECOIA
- Status last verified
- Jun 2026
- First submitted
- 7 Sep 2021
- Last updated
- 2 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Percutaneous A1 Pulley Release Under Ultrasound Guidance Associated With Infiltration, Versus Infiltration Alone, in Patients With Trigger Finders Who Have Failed a First Infiltration: a Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT05045157
- Acronym / sponsor ID
- SECOIA / CHD21_0024
- Conditions
- Trigger Finger
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Centre Hospitalier Departemental VendeeUniversity, hospital or other
- Study start
- 31 May 2022 (actual)
- Primary completion
- 31 May 2026 (actual)
- Study completion
- 31 May 2027 (estimated)
- First posted
- 16 Sep 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Trigger finger is a mechanical problem characterized by pain and catching of digit in flexion.
Histological changes of A1 pulley and synovial proliferation have been identified as factors that prompt trigger finger The first-line treatment of trigger finger is conservative with splinting and corticosteroid injection.
If the first infiltration fails, either a second infiltration or surgical sectioning of the pulley is proposed.
Surgery can be performed by several techniques (open section, percutaneous section with palpatory guidance, or under ultrasound guidance).
Percutaneous A1 pulley release under ultrasound guidance consists of cutting the A1 pulley by a percutaneous insertion with small needle under local anaesthesia.
The hypothesis of the study is that percutaneous A1 pulley release under ultrasound guidance followed by a corticosteroid injection would be more effective than a second corticosteroid injection alone on complete resolution of the trigger finger symptoms
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| percutaneous A1 pulley release with corticosteroid injection | Experimental | Procedure: Percutaneous A1 Pulley Release Under Ultrasound Guidance, Drug: Corticosteroid injection |
| corticosteroid injection alone | Active comparator | Drug: Corticosteroid injection |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (9 listed)
- Patient ≥ 18 years old,
- Presence of a trigger finger (thumb or long fingers) to be treated
- Quinnell score >1
- Episode of trigger characterized on questioning or clinical examination
- Failure of a first corticosteroid infiltration > 3 months before inclusion
Key exclusion criteria (19 listed)
- Presence of several symptomatic fingers requiring treatment by ultrasound-guided section of the pulley
- Patient who are pregnant, breastfeeding, or who have the potential to become pregnant without effective contraception at the time of inclusion
- Known allergy to corticoid (Hydrocortancyl®) including its excipients ((benzyl alcohol, sodium carmellose, sodium chloride, polysorbate 80)
- Known allergies to lidocaine
- Ongoing anticoagulant treatments (AVK, New Oral Anti-Coagulants)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Percutaneous A1 Pulley Release Under Ultrasound Guidancethe A1 pulley is cut off with Ultrasound guidance by a percutaneous insertion of the small needle under local anaesthesia. | Procedure or surgery | percutaneous A1 pulley release with corticosteroid injection |
| Corticosteroid injectioncorticosteroid injection is performed | Drug | corticosteroid injection alone, percutaneous A1 pulley release with corticosteroid injection |
Primary outcome
Effectiveness of pulley section with ultrasound guidance combined with corticosteroid infiltration versus corticosteroid alone on complete resolution of trigger finger's symptoms
Time frame: 1 year postoperatively
Trigger finger's symptoms defined by a clinical Quinnell score ≤1 without the use of an alternative therapy
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Grégoire Cormier, Dr principal investigator
CHD Vendée
4 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Percutaneous A1 Pulley Release Under Ultrasound Guidance and Corticosteroid injection in people with Trigger Finger, run by Centre Hospitalier Departemental Vendee at 4 sites in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 19 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 2 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Effectiveness of pulley section with ultrasound guidance combined with corticosteroid infiltration versus corticosteroid alone on complete resolution of trigger finger's symptoms (time frame: 1 year postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jun 2026.