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Psychiatric IllnessNCT05133726

Peer and Text Message Support to Reduce Readmission Rates for Patients Discharged From Acute Psychiatric Care

A study testing Text4Support and Peer support in people with Psychiatric Illness, run by University of Alberta at 7 sites in Canada.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Avoidable hospital readmissions are a pressing problem for our healthcare system. They lead to substantial human suffering and higher financial costs. Most discharged psychiatric inpatients in Alberta are offered follow-up appointments with Alberta Health Services (AHS) Addiction and Mental Health (AMH) community… Read more about this study

Who is it for?
Ages 18 to 65 years
Conditions the study is for
Psychiatric Illness
What is being tested?
Text4Support and Peer support
Could I receive a placebo?
No, everyone receives an active treatment
How many people
1,149 participants
Where
7 sitesCanada
Study dates
1 Mar 2022to 30 Jun 2026
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 65 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Patients who are 18 or 65 years of age
  • Able to provide informed written consent have been diagnosed with mental health condition, and are ready for discharge.
  • Patients should have a mobile device capable of receiving text messages

Who cannot join

  • Patients will be ineligible if they do not meet the above inclusion criteria,
  • If they have an addiction disorder but not a mental health diagnosis
  • Are not capable of reading text messages from a mobile device or if they know they will be out of town during the 12-month follow-up period.
  • Patients are also ineligible if they do not consent to take part in the study,

Trial locations and contacts

7 sites in 1 country.

7 sites in 1 country

Canada7 sites
  • Foothills Hospital

    Calgary

  • Royal Alexander Hospital

    Edmonton, Alberta, T5H2V1

  • Alberta Hospital

    Edmonton, Alberta, T5J2J7

  • Misericordia Community Hospital

    Edmonton, Alberta, T5R4H5

  • University of Alberta Hospital

    Edmonton, Alberta, T6G2R3

  • Grey Nuns Hospital

    Edmonton, Alberta, T6L5X8

  • Northern Lights Regional Health Centre

    Fort McMurray, Alberta

Other trials in Canada

About this study

Official title: Reducing Inpatient Readmission Rates for Patients Discharged From Acute Psychiatric Care in Alberta Using Peer and Text Message Support: Protocol for an Innovative Supportive Program

Avoidable hospital readmissions are a pressing problem for our healthcare system. They lead to substantial human suffering and higher financial costs. Most discharged psychiatric inpatients in Alberta are offered follow-up appointments with Alberta Health Services (AHS) Addiction and Mental Health (AMH) community providers. Patients often wait 28-38 weeks for their first appointment, which leads many to miss their first appointments, and increases the likelihood of relapse. As a result, patients discharged into the community are readmitted to the Emergency Department (ED). To address this significant revolving door, the investigators will implement a low-cost, evidence-based system that delivers daily supportive texts to patients' mobile phones. The text messages developed by experts and service users, based on cognitive behavioral therapy principles. Our proposed program also includes peer support from previous mental health patients who have had similar challenges as participants, but are now in recovery. In this way, the investigators aim to reduce the psychological treatment and support gap for AMH patients who have been discharged from acute care and are scheduled to receive mental health and psychiatric treatment from A\&MH services after a long wait. Our pilot test of these interventions provide evidence that psychiatric readmissions, and emergency department visits can be reduced by 10-25% if implemented at scale in Alberta, thus resulting in cost-savings for individuals and the province.

Read the detailed description

Background \& Rational Avoidable hospital readmission is a growing concern in health systems across the world. Readmissions often lead to significant physical, psychological and financial suffering on the part of patients and their families. The health system is also affected by high readmission rates. Infrastructural, human and financial resources, which are limited, often get stretched. This is particularly true in the era of the 2019 corona virus disease (COVID-19) pandemic, which has seen many hospitals overwhelmed by rising emergency presentations. Consequently, there is a renewed interest to seek out solutions to mitigate avoidable readmissions, particularly in acute care.

Patients with psychiatric disorders have the highest early readmission rates among all hospitalized patients. Early readmission is defined as readmission within 30 days of previous discharge. Whereas deinstitutionalization of care and transition to community-based mental health care has been an approach of focus for decades, early hospital readmission remains high. Unmet need for psychological treatment and the limited human resources to address this gap is a major cause of high 30-day readmissions rates in mental acute units.

In Alberta, Canada, about 8.4-11.9% of residents suffer from mental illness, but less than 25% of these patients report that their mental health care needs were fully met. This is despite almost 70% of mental health patients utilizing a provincial mental health service the year before, according to a 2014 mental health gap assessment report. The greatest unmet need cited is the lack of sufficient, accessible, and affordable counselling. Their next greatest concern was an unmet need for tailored information on their own mental health challenges. This is despite the 426 distinct interventions within AHS to address addiction and mental health challenges through community health clinics, and free-standing AMH facilities, among others. Interestingly, 86% of Alberta Health Services direct providers believe that they provide sufficient information to clients. This contradiction between patients and community providers' perspectives reinforces concerns that services may not be well tailored to the diverse perceived needs of various patient groups. A consequence of this gap is the high demand for more specialist services, and high readmissions after discharge from a recent hospital stay with attendant implications on the cost of health services. One study reports 90-day readmission rates of up to 14.0%, with the median time to readmission being 24 days. More findings from the 2014 mental health gap assessment revealed that current management strategies are reactive, with system resources heavily invested in inpatient, residential and crisis services. Technology was noted to be under-utilized in the province. Reducing the felt need for hospital visits by providing alternative effective care will mitigate the existing strain on healthcare human and financial resources due to mental health challenges. To address this challenge, the investigators propose an innovative program which augments peer support from previous mental health patients now in recovery with an evidence-based supportive text messaging developed using the principles of cognitive behavioral therapy (CBT).

Components of the innovation

  1. Peer support is valued in recovery-oriented models of mental health and increasingly implemented. Evidence indicates positive effects, including lower inpatient service use, better relationships with providers and increased engagement. Peer Support Workers (PSWs) who are in recovery and have lived experience as former patients will play central roles in this study, including delivering some of the interventions proposed. PSW activities will include supportive face-to-face visits, interactive phone calls/texts/zoom meetings with patients, advocacy, connecting patients with community resources, and experiential sharing. PSWs will be actively engaged through all provincial practice councils, they are embedded within many Alberta addiction and mental health (AMH) programs, making this solution workable. Evidence also shows that peers support may also benefit peer PSWs, enhancing feelings of competence and personal value.
  2. Text4Support to be provided through ResilienceNHope online application (https://application.resiliencenhope.com/), is a low cost, evidence-based, supportive text messaging program which will be coupled with or without peer support services to reduce the psychological treatment and support gap for A\&MH patients who have been discharged from acute care into community. Starting a day after enrolment, intervention-group patients will receive daily unidirectional (no-reply) supportive text messages. The messages will be written by cognitive behavior therapists in partnership with patients and preprogramed into ResilienceNHope which will deliver the messages to the patients. The Text4Support program was developed based on knowledge from randomized controlled trials conducted in Ireland and Alberta. The program is also based on knowledge from the highly successful award winning Text4Mood program in Alberta's North Zone which improved the psychological treatment gap and was effective, scalable (i.e., > 10,000 recipients within 6 months) and the Text4Hope program launched in Alberta during the COVID 19 pandemic which was also effective and scalable (> 48,000 subscribers within 3 months). Text4Support provides Cognitive Behavioral Therapy (CBT)-based and diagnosis-specific (i.e., mood disorders, anxiety disorders, schizophrenia and other psychotic disorders, substance use disorders, adjustment disorders or personality disorders), daily supportive text messages for 6 months. Some examples of the text messages are:
  • What lies behind you and what lies before you are tiny matters compared to what lies within you. Have faith in yourself, and success can be yours.
  • There are 2 days in the week we should not worry about, yesterday and tomorrow. That leaves today. Live for today.
  • Stumbling blocks can become stepping stones to a better life. You can turn adversities into opportunities. Don't be discouraged by today's problems.
  • Letting go of resentment is a gift you give yourself. It will ease your journey immeasurably. Make peace with everyone, and happiness will be yours.

With respect to content, analysis of Alberta service data suggests that diagnostic clusters for patients discharged from acute into community for follow-up falls into six major categories: mood disorders, anxiety disorders, schizophrenia and other psychotic disorders, substance use disorders, adjustment disorders and personality disorders. Thus, text message content will focus on two dimensions. First, general content that is indicated regardless of symptomatology will be presented, including messages of self-care, social support, hope, affirmation, and recovery. Second, specific content will be provided that focuses on management of symptoms related to the specific conditions described above (e.g., activity scheduling in depression). As a component of scalability and inclusiveness, text message content can also be customized based on end user characteristics. Specifically, the investigators will explore content that is sensitive to needs based on age group, cultural identity, gender identification, and non-English language communication. This serves to enhance access for diverse groups, many of whom may be marginalized or underserved. In addition, patients identified to be most at-risk of readmission to hospital will be offered peer support, which also takes into account age and gender of both the patient and PSWs. Options for matching patients and PSWs by cultural identity and sexual orientation will be explored as the project is scaled up and the pool of PSWs increases. Consequently, recruitment of PSWs will take into account diversity in age, gender, cultural identity and sexual orientation.

Study aim This study is designed to address gaps in care/support available at the community level for psychiatric patients discharged from hospital and referred to community mental health services for follow-up. The investigators aim to reduce the psychological treatment and support gap for AMH patients who have been discharged from acute care and are scheduled to receive mental health and psychiatric treatment from AMH services after a long wait. Our pilot test (unpublished) of these interventions provide evidence that psychiatric readmissions, and emergency department visits can be reduced by 10-25% if implemented at scale in Alberta, thus resulting in cost-savings for individuals and the province.

Methods and analysis This study will both evaluate the effectiveness of this intervention as well as implementation context and outcomes. The Consolidated Framework for Implementation Research (CFIR) will provide an overarching guidance to design, implementation, and evaluation by examining outer/inner contexts, intervention characteristics, and stakeholders involved as well as the process of implementation.

Further, using the Reach-Effectiveness-Adoption-Implementation- Maintenance (RE-AIM) framework, the investigators will: examine the reach of the interventions, i.e., text and peer support; evaluate their effectiveness; gauge support for their adoption; evaluate fidelity in implementation; and document the maintenance (sustainability) of implementation post-trail.

Study design A pragmatic stepped-wedge cluster-randomized approach will be applied, providing Text4Support and Peer Support Service (PSS) to 10,800 patients recruited across 11 acute care sites and day hospitals across Alberta as the clustered unit of randomization. The design reconciles constraints under which policy makers and service managers operate with need for rigorous scientific evaluations. In a stepped-wedge study, the design is extended so every cluster provides pre-post observations, and switches from control to intervention exposure but not at the same time-point.

This design has been successfully used to implement complex programs and change management involving large-scale programs in many countries. The study also adheres to the various checklists from the EQUATOR network.

Being tested
Text4Support, Peer support
Keywords
Psychiatric Illness, Peer support, Text Message, Electronic health (eHealth), Readmission rate
Medical subject headings
Mental Disorders

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Text4SupportOther

    Also called Supportive messages

    Daily supportive text messages

  • Peer supportOther

    Meeting with peers who have lived experiences with similar diagnoses but are in recovery

Study groups in NCT05133726
Study groupRoleWhat they receive
Text Message clusterExperimentalThis arm will receive only daily text message support for six months plus weekly text message over 6 weeks (six information text messages all together)
Receives: Other: Text4Support
Text message with or without peer supportExperimentalAll individuals in this cluster will receive daily text message support for six months plus weekly text message over 6 weeks (six information text messages all together) with some selected members also receiving peer support for six months
Receives: Other: Text4Support; Other: Peer support
Control groupNo interventionThis group will only receive usual care plus weekly text message over 6 weeks (six information text messages all together) with provides information about community services

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Change in 30 day readmission rate

    Readmission to acute psychiatric care within 30 days of discharge

    Measured: baseline, 24 weeks, 52 weeks

Secondary outcomes (5)
  1. Change in Clinical Outcomes in Routine Evaluation 10 (CORE-10) scores

    The CORE-10 is a short 10 item easy-to-use assessment measure for common presentations of psychological distress, designed to be used for screening as well as over the course of treatment to track progress. The measure is a shortened version of the 34 item CORE Outcome Measure tool, both of which ask respondents to self-report symptoms over the past week.

    Measured: baseline, 24 weeks, 52 weeks

  2. Change in EuroQol- 5 Dimension (EQ-5D)scores

    EQ-5D is an instrument which evaluates the generic quality of life

    Measured: baseline, 24 weeks, 52 weeks

  3. Change in Patient Health Questionnaire (PHQ-9) scores

    The PHQ-9 is a multipurpose instrument for screening, diagnosing, monitoring and measuring the severity of depression: n The PHQ-9 incorporates the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) depression diagnostic criteria with other leading major depressive symptoms into a brief self-report tool.

    Measured: baseline, 24 weeks, 52 weeks

  4. Change in Recovery Assessment Scale (RAS)scores

    The RAS is a 20-item measure developed as an outcome measure for program evaluations. Based on a process model of recovery, the RAS attempts to assess aspects of recovery with a special focus on hope and self-determination.

    Measured: baseline, 24 weeks, 52 weeks

  5. Change in Brief Resilience Scale scores

    The Brief Resilience Scale was created to assess the perceived ability to bounce back or recover from stress. The scale was developed to assess a unitary construct of resilience, including both positively and negatively worded items. The possible score range is from 1 (low resilience) to 5 (high resilience).

    Measured: baseline, 24 weeks, 52 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted24 Nov 2021
  2. Study start1 Mar 2022
  3. Primary completion31 Mar 2024
  4. Study completion30 Jun 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Randomised
Intervention model
Sequential
Model description
Stepped edge design
Masking
None (open label)
Enrolment
1,149 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT05133726
Sponsor's protocol ID
Pro00111459
Status last verified
Sep 2026
First submitted
21 Oct 2021
Last updated
11 Sep 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: Health service utilization information will be collected (for the year prior to admission, and the year post-discharge). This data will include: inpatient admissions and length of stay, readmissions, completed appointments, Emergency Department presentations, Emergency Medical Services use, community services appointments, crisis and urgent service calls, appointment no show rates

Publications

  • Adu MK, Shalaby R, Eboreime E, Sapara A, Nkire N, Chawla R, Chima C, Achor M, Osiogo F, Chue P, Greenshaw AJ, Agyapong VI. Text Messaging Versus Email Messaging to Support Patients With Major Depressive Disorder: Protocol for a Randomized Hybrid Type II Effectiveness-Implementation Trial. JMIR Res Protoc. 2021 Oct 13;10(10):e29495. doi: 10.2196/29495.

    PubMed 34643541
  • Agyapong VIO, Juhas M, Ohinmaa A, Omeje J, Mrklas K, Suen VYM, Dursun SM, Greenshaw AJ. Randomized controlled pilot trial of supportive text messages for patients with depression. BMC Psychiatry. 2017 Aug 2;17(1):286. doi: 10.1186/s12888-017-1448-2.

    PubMed 28768493
  • Shalaby RAH, Agyapong VIO. Peer Support in Mental Health: Literature Review. JMIR Ment Health. 2020 Jun 9;7(6):e15572. doi: 10.2196/15572.

    PubMed 32357127
  • Agyapong VI, Mrklas K, Juhas M, Omeje J, Ohinmaa A, Dursun SM, Greenshaw AJ. Cross-sectional survey evaluating Text4Mood: mobile health program to reduce psychological treatment gap in mental healthcare in Alberta through daily supportive text messages. BMC Psychiatry. 2016 Nov 8;16(1):378. doi: 10.1186/s12888-016-1104-2.

    PubMed 27821096
  • Agyapong VI, Ahern S, McLoughlin DM, Farren CK. Supportive text messaging for depression and comorbid alcohol use disorder: single-blind randomised trial. J Affect Disord. 2012 Dec 10;141(2-3):168-76. doi: 10.1016/j.jad.2012.02.040. Epub 2012 Mar 29.

    PubMed 22464008
  • Owusu E, Mao W, Shalaby R, Elgendy HE, Agyapong B, Eboreime E, Mobolaji LA, Nkire N, Silverstone PH, Chue P, Vuong W, Ohinmaa A, Taylor V, Hilario CT, Greenshaw AJ, Agyapong V. The correlates and rate of readmission six months post-discharge from inpatient psychiatric units in Alberta. JMIR Form Res. 2026 Oct 7. doi: 10.2196/96221. Online ahead of print.

    PubMed 42855840
  • Mao W, Shalaby R, Owusu E, Elgendy HE, Agyapong B, Chue P, Silverstone PH, Greenshaw AJ, Li XM, Eboreime E, Vuong W, Ohinmaa A, MacMaster FP, Agyapong VIO. Predictors of Psychiatric Emergency Department Visits Following Inpatient Discharge: Secondary Analysis of a Stepped-Wedge Cluster Randomized Trial. JMIR Form Res. 2026 Mar 30;10:e79184. doi: 10.2196/79184.

    PubMed 41911338
  • Agyapong VIO, Shalaby R, Agyapong B, Mao W, Owusu E, Elgendy HE, Eboreime E, Silverstone PH, Chue P, Li XM, Vuong W, Ohinmaa A, MacMaster F, Greenshaw AJ. Effectiveness of Text Messages and Text Messages Plus Peer Support on Psychiatric Readmission and Length of Stay: Outcomes From a Quantitative Stepped-Wedge Cluster Randomized Trial. JMIR Ment Health. 2025 Nov 18;12:e81760. doi: 10.2196/81760.

    PubMed 41108215
  • Owusu E, Mao W, Shalaby R, Elgendy HE, Agyapong B, Eboreime E, Lawal MA, Nkire N, Wei Y, Silverstone PH, Chue P, Li XM, Vuong W, Ohinmaa A, Taylor V, Hilario CT, Greenshaw AJ, Agyapong VIO. The prevalence and correlates of low resilience in patients prior to discharge from acute psychiatric units in Alberta, Canada. BMC Psychiatry. 2025 Mar 27;25(1):295. doi: 10.1186/s12888-025-06704-8.

    PubMed 40148879
  • Eboreime E, Shalaby R, Mao W, Owusu E, Vuong W, Surood S, Bales K, MacMaster FP, McNeil D, Rittenbach K, Ohinmaa A, Bremault-Phillips S, Hilario C, Greiner R, Knox M, Chafe J, Coulombe J, Xin-Min L, McLean C, Rathwell R, Snaterse M, Spurvey P, Taylor VH, McLean S, Urichuk L, Tzeggai B, McCabe C, Grauwiler D, Jordan S, Brown E, Fors L, Savard T, Grunau M, Kelton F, Stauffer S, Cao B, Chue P, Abba-Aji A, Silverstone P, Nwachukwu I, Greenshaw A, Agyapong VIO. Reducing readmission rates for individuals discharged from acute psychiatric care in Alberta using peer and text message support: Protocol for an innovative supportive program. BMC Health Serv Res. 2022 Mar 12;22(1):332. doi: 10.1186/s12913-022-07510-8.

    PubMed 35279142

Questions about this trial

What is this clinical trial studying?

A study testing Text4Support and Peer support in people with Psychiatric Illness, run by University of Alberta at 7 sites in Canada.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 11 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 7 sites in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change in 30 day readmission rate (time frame: baseline, 24 weeks, 52 weeks). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT05133726, which also lists 10 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Sep 2026.

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