Knee OsteoarthritisNCT05334524
Kinesiotaping With and Without Combined Chain Exercises in Patients With Knee Osteoarthritis
A study testing kinesiotaping with combined chain exercises and kinesiotaping in people with Knee Osteoarthritis, run by Riphah International University at 1 site in Pakistan.
Trial summary
Knee osteoarthritis is a major public health issue because it causes chronic pain, reduces physical function and diminishes quality of life. Aging of the population and increased global prevalence of obesity are anticipated to dramatically increase the prevalence of knee osteoarthritis. Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Knee Osteoarthritis
- What is being tested?
- kinesiotaping with combined chain exercises and kinesiotaping
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 38 participants
- Where
- 1 sitePakistan
- Study dates
- 30 Nov 2021to 31 Jul 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Male and female patients.
- Patients age between 40 years- 60years.
- Patients with Grade II knee osteoarthritis.
Who cannot join
- Patients with allergic reaction to tape or any skin problems
- Patients with history of injection at the knee.
- Patients with surgical intervention at the knee
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Kinesiotaping With and Without Combined Chain Exercises on Pain, Range of Motion and Quality of Life in Patients With Knee Osteoarthritis
Knee osteoarthritis is a major public health issue because it causes chronic pain, reduces physical function and diminishes quality of life. Aging of the population and increased global prevalence of obesity are anticipated to dramatically increase the prevalence of knee osteoarthritis. Knee osteoarthritis is characterized by complex multifactorial joint pathology and is the most common form of joint disorder in the world. Chronic knee osteoarthritis leads to marked weakening of the quadriceps femoris muscle, which is the extensor and stabilizer of the knee and atrophy of this muscle result knee pain and functional impairment. Quadriceps muscle weakness and atrophy have been reported to contribute to functional impairment and pain in patients with knee osteoarthritis and quadriceps strengthening can be achieved through open kinetic chain exercises and close kinetic chain exercises. Close kinetic chain exercises are modeled as, in which a movement in a joint simultaneously produces movements in other joints of the extremity. Open kinetic chain exercises and close kinetic chain exercises form the combined chain exercises. Kinesiotaping with these exercises to improve the patients suffering with knee osteoarthritis. The aim of this study will be to compare the effects of kinesiotaping as an adjunct to combined chain exercises compared with only kinesiotaping on pain, range of motion and quality of life in the management of individuals with knee osteoarthritis.
This study will be randomized control trial. Patients will be recruited into two groups by simple random assignment. Non probability consecutive sampling technique will be used. Data will be collected from patients of grade 2 knee osteoarthritis patients by using NPRS for pain, Goniometer for ROM and SF-36 for quality of life will be used before and immediate after the treatment. Those who will meet the inclusion criteria will be recruited. Group 1 will be treated with kinesiotaping and combined chain exercises and the Group 2 will be treated with only kinesiotaping on knee OA patients. Total intervention will be given for four weeks for three sessions per week.The subject attended physical therapy and kinesiotaping will assess for pain, range of motion and quality of life at baseline and after 4 week of intervention. After collecting data from defined study setting, data will be entered and analyzed by using Statistical Package for the Social Sciences (SPSS) for Windows software, version 25.
- Conditions
- Knee Osteoarthritis
- Being tested
- kinesiotaping with combined chain exercises, kinesiotaping
- Keywords
- Knee osteoarthritis, Kinesiotaping, Combined chain exercises, Pain, ROM, quality of life
- Medical subject headings
- Osteoarthritis, Knee, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
kinesiotaping with combined chain exercisesOther
3 Kinesiotape strips will be applied: 2 "Y-strips" with a length of approximately 20 cm and an anchor of 2 cm and a single longitudinal section (1 "I-strip"). Tails of the quadriceps strip were applied to the patella, wrapping the patella medially and laterally with 25% tension and the (I-strip) will be applied with 75% tension.
Combined chain exercises will apply with 10 secs hold with 10 repetitions which will include quadriceps setting, SLR, full arc extension, cycling in the air, wall slides and step-up and step-down exercises
kinesiotapingOther
3 Kinesiotape strips will be applied: 2 "Y-strips" with a length of approximately 20 cm and an anchor of 2 cm and a single longitudinal section (1 "I-strip"). Tails of the quadriceps strip were applied to the patella, wrapping the patella medially and laterally with 25% tension and the (I-strip) will be applied with 75% tension
| Study group | Role | What they receive |
|---|---|---|
| kinesiotaping with combined chain exercises | Active comparator | 3 Kinesiotape strips will be applied: 2 "Y-strips" with a length of approximately 20 cm and an anchor of 2 cm and a single longitudinal section (1 "I-strip"). Tails of the quadriceps strip were applied to the patella, wrapping the patella medially and laterally with 25% tension and the (I-strip) will be applied with 75% tension.
Combined chain exercises will apply with 10 secs hold with 10 repetitions which will include quadriceps setting, SLR, full arc extension, cycling in the air, wall slides and step-up and step-down exercises. Receives: Other: kinesiotaping with combined chain exercises; Other: kinesiotaping |
| kinesiotaping | Active comparator | 3 Kinesiotape strips will be applied: 2 "Y-strips" with a length of approximately 20 cm and an anchor of 2 cm and a single longitudinal section (1 "I-strip"). Tails of the quadriceps strip were applied to the patella, wrapping the patella medially and laterally with 25% tension and the (I-strip) will be applied with 75% tension. Receives: Other: kinesiotaping |
What is being measured
The primary outcome is the main question the study is designed to answer.
NPRS
used for pain measurement, It is a uni-dimensional 11 point scale (0-10) with measure of pain intensity with High test-retest reliability of r = 0.96 and validity correlations range from 0.86 to 0.95 (7).
Measured: 4th week
Goniometry
It is a device that measures an angle or permits the rotation of an object to a definite position
Measured: 4th week
SF-36 Questionnaire
For quality of life SF-36 questionnaire is used. The questionnaire consists of 36 items on physical and social functioning and has 8 domains. The total score ranges from 0 to 100, with higher scores indicating better quality of life and lower scores indicating the worse quality of life
Measured: 4th week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Apr 2022
- Study start30 Nov 2021
- Primary completion30 Jun 2022
- Study completion31 Jul 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (7)Papers the sponsor has linked to this study.
- Other trials for Knee OsteoarthritisStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 38 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Hina Gul, t-DPT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05334524
- Sponsor's protocol ID
- REC/Lhr/21/0132 Sobia
- Status last verified
- Dec 2022
- First submitted
- 2 Apr 2022
- Last updated
- 20 Dec 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Kaya Mutlu E, Mustafaoglu R, Birinci T, Razak Ozdincler A. Does Kinesio Taping of the Knee Improve Pain and Functionality in Patients with Knee Osteoarthritis?: A Randomized Controlled Clinical Trial. Am J Phys Med Rehabil. 2017 Jan;96(1):25-33. doi: 10.1097/PHM.0000000000000520.
PubMed 27149590Olagbegi OM, Adegoke BOA, Odole AC. Effectiveness of combined chain exercises on pain and function in patients with knee osteoarthritis. Bangladesh Journal of Medical Science. 2016;15(2):178-88.
Danazumi MS, Ibrahim SU, Yakasai AM, Dermody G, Bello B, Kaka B. A Comparison Between the Effect of Combined Chain Exercises Plus Kinesio Taping With Combined Chain Exercises Alone in Knee Osteoarthritis: A Randomized Clinical Trial. Am J Phys Med Rehabil. 2021 Nov 1;100(11):1070-1077. doi: 10.1097/PHM.0000000000001705.
PubMed 33496439Rahlf AL, Braumann KM, Zech A. Kinesio Taping Improves Perceptions of Pain and Function of Patients With Knee Osteoarthritis: A Randomized, Controlled Trial. J Sport Rehabil. 2019 Jul 1;28(5):481-487. doi: 10.1123/jsr.2017-0306. Epub 2018 Dec 12.
PubMed 29466081Abolhasani M, Halabchi F, Afsharnia E, Moradi V, Ingle L, Shariat A, Hakakzadeh A. Effects of kinesiotaping on knee osteoarthritis: a literature review. J Exerc Rehabil. 2019 Aug 28;15(4):498-503. doi: 10.12965/jer.1938364.182. eCollection 2019 Aug.
PubMed 31523668Ye W, Jia C, Jiang J, Liang Q, He C. Effectiveness of Elastic Taping in Patients With Knee Osteoarthritis: A Systematic Review and Meta-Analysis. Am J Phys Med Rehabil. 2020 Jun;99(6):495-503. doi: 10.1097/PHM.0000000000001361.
PubMed 31851010Olagbegi OM, Adegoke BO, Odole AC. Effectiveness of three modes of kinetic-chain exercises on quadriceps muscle strength and thigh girth among individuals with knee osteoarthritis. Arch Physiother. 2017 Jul 19;7:9. doi: 10.1186/s40945-017-0036-6. eCollection 2017.
PubMed 29340203
Study at a glance
From the registry record, last updated by the sponsor on 20 Dec 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Kinesiotaping With and Without Combined Chain Exercises on Pain, Range of Motion and Quality of Life in Patients With Knee Osteoarthritis
- ClinicalTrials.gov ID
- NCT05334524
- Acronym / sponsor ID
- REC/Lhr/21/0132 Sobia
- Conditions
- Knee Osteoarthritis
- Keywords
- Knee osteoarthritis, Kinesiotaping, Combined chain exercises, Pain, ROM, quality of life
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 38 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 30 Nov 2021 (actual)
- Primary completion
- 30 Jun 2022 (actual)
- Study completion
- 31 Jul 2022 (actual)
- First posted
- 19 Apr 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Knee osteoarthritis is a major public health issue because it causes chronic pain, reduces physical function and diminishes quality of life. Aging of the population and increased global prevalence of obesity are anticipated to dramatically increase the prevalence of knee osteoarthritis. Knee osteoarthritis is characterized by complex multifactorial joint pathology and is the most common form of joint disorder in the world. Chronic knee osteoarthritis leads to marked weakening of the quadriceps femoris muscle, which is the extensor and stabilizer of the knee and atrophy of this muscle result knee pain and functional impairment. Quadriceps muscle weakness and atrophy have been reported to contribute to functional impairment and pain in patients with knee osteoarthritis and quadriceps strengthening can be achieved through open kinetic chain exercises and close kinetic chain exercises. Close kinetic chain exercises are modeled as, in which a movement in a joint simultaneously produces movements in other joints of the extremity. Open kinetic chain exercises and close kinetic chain exercises form the combined chain exercises. Kinesiotaping with these exercises to improve the patients suffering with knee osteoarthritis. The aim of this study will be to compare the effects of kinesiotaping as an adjunct to combined chain exercises compared with only kinesiotaping on pain, range of motion and quality of life in the management of individuals with knee osteoarthritis.
This study will be randomized control trial. Patients will be recruited into two groups by simple random assignment. Non probability consecutive sampling technique will be used. Data will be collected from patients of grade 2 knee osteoarthritis patients by using NPRS for pain, Goniometer for ROM and SF-36 for quality of life will be used before and immediate after the treatment. Those who will meet the inclusion criteria will be recruited. Group 1 will be treated with kinesiotaping and combined chain exercises and the Group 2 will be treated with only kinesiotaping on knee OA patients. Total intervention will be given for four weeks for three sessions per week.The subject attended physical therapy and kinesiotaping will assess for pain, range of motion and quality of life at baseline and after 4 week of intervention. After collecting data from defined study setting, data will be entered and analyzed by using Statistical Package for the Social Sciences (SPSS) for Windows software, version 25.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| kinesiotaping with combined chain exercises | Active comparator | Other: kinesiotaping with combined chain exercises, Other: kinesiotaping3 Kinesiotape strips will be applied: 2 "Y-strips" with a length of approximately 20 cm and an anchor of 2 cm and a single longitudinal section (1 "I-strip"). Tails of the quadriceps strip were applied to the patella, wrapping the patella medially and laterally with 25% tension and the (I-strip) will be applied with 75% tension. Combined chain exercises will apply with 10 secs hold with 10 repetitions which will include quadriceps setting, SLR, full arc extension, cycling in the air, wall slides and step-up and step-down exercises. |
| kinesiotaping | Active comparator | Other: kinesiotaping3 Kinesiotape strips will be applied: 2 "Y-strips" with a length of approximately 20 cm and an anchor of 2 cm and a single longitudinal section (1 "I-strip"). Tails of the quadriceps strip were applied to the patella, wrapping the patella medially and laterally with 25% tension and the (I-strip) will be applied with 75% tension. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Male and female patients.
- Patients age between 40 years- 60years.
- Patients with Grade II knee osteoarthritis.
Key exclusion criteria (3 listed)
- Patients with allergic reaction to tape or any skin problems
- Patients with history of injection at the knee.
- Patients with surgical intervention at the knee
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| kinesiotaping with combined chain exercises3 Kinesiotape strips will be applied: 2 "Y-strips" with a length of approximately 20 cm and an anchor of 2 cm and a single longitudinal section (1 "I-strip"). Tails of the quadriceps strip were applied to the patella, wrapping the patella medially and laterally with 25% tension and the (I-strip) will be applied with 75% tension. Combined chain exercises will apply with 10 secs hold with 10 repetitions which will include quadriceps setting, SLR, full arc extension, cycling in the air, wall slides and step-up and step-down exercises | Other | kinesiotaping with combined chain exercises |
| kinesiotaping3 Kinesiotape strips will be applied: 2 "Y-strips" with a length of approximately 20 cm and an anchor of 2 cm and a single longitudinal section (1 "I-strip"). Tails of the quadriceps strip were applied to the patella, wrapping the patella medially and laterally with 25% tension and the (I-strip) will be applied with 75% tension | Other | kinesiotaping, kinesiotaping with combined chain exercises |
Primary outcome
NPRS
Time frame: 4th week
used for pain measurement, It is a uni-dimensional 11 point scale (0-10) with measure of pain intensity with High test-retest reliability of r = 0.96 and validity correlations range from 0.86 to 0.95 (7).
Goniometry
Time frame: 4th week
It is a device that measures an angle or permits the rotation of an object to a definite position
SF-36 Questionnaire
Time frame: 4th week
For quality of life SF-36 questionnaire is used. The questionnaire consists of 36 items on physical and social functioning and has 8 domains. The total score ranges from 0 to 100, with higher scores indicating better quality of life and lower scores indicating the worse quality of life
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Dec 2022.
- Background: PubMed 27149590Kaya Mutlu E, Mustafaoglu R, Birinci T, Razak Ozdincler A. Does Kinesio Taping of the Knee Improve Pain and Functionality in Patients with Knee Osteoarthritis?: A Randomized Controlled Clinical Trial. Am J Phys Med Rehabil. 2017 Jan;96(1):25-33. doi: 10.1097/PHM.0000000000000520.
- BackgroundOlagbegi OM, Adegoke BOA, Odole AC. Effectiveness of combined chain exercises on pain and function in patients with knee osteoarthritis. Bangladesh Journal of Medical Science. 2016;15(2):178-88.
- Background: PubMed 33496439Danazumi MS, Ibrahim SU, Yakasai AM, Dermody G, Bello B, Kaka B. A Comparison Between the Effect of Combined Chain Exercises Plus Kinesio Taping With Combined Chain Exercises Alone in Knee Osteoarthritis: A Randomized Clinical Trial. Am J Phys Med Rehabil. 2021 Nov 1;100(11):1070-1077. doi: 10.1097/PHM.0000000000001705.
- Background: PubMed 29466081Rahlf AL, Braumann KM, Zech A. Kinesio Taping Improves Perceptions of Pain and Function of Patients With Knee Osteoarthritis: A Randomized, Controlled Trial. J Sport Rehabil. 2019 Jul 1;28(5):481-487. doi: 10.1123/jsr.2017-0306. Epub 2018 Dec 12.
- Background: PubMed 31523668Abolhasani M, Halabchi F, Afsharnia E, Moradi V, Ingle L, Shariat A, Hakakzadeh A. Effects of kinesiotaping on knee osteoarthritis: a literature review. J Exerc Rehabil. 2019 Aug 28;15(4):498-503. doi: 10.12965/jer.1938364.182. eCollection 2019 Aug.
- Background: PubMed 31851010Ye W, Jia C, Jiang J, Liang Q, He C. Effectiveness of Elastic Taping in Patients With Knee Osteoarthritis: A Systematic Review and Meta-Analysis. Am J Phys Med Rehabil. 2020 Jun;99(6):495-503. doi: 10.1097/PHM.0000000000001361.
- Background: PubMed 29340203Olagbegi OM, Adegoke BO, Odole AC. Effectiveness of three modes of kinetic-chain exercises on quadriceps muscle strength and thigh girth among individuals with knee osteoarthritis. Arch Physiother. 2017 Jul 19;7:9. doi: 10.1186/s40945-017-0036-6. eCollection 2017.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Hina Gul, t-DPT principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing kinesiotaping with combined chain exercises and kinesiotaping in people with Knee Osteoarthritis, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Dec 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NPRS (time frame: 4th week). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05334524, which also lists 7 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Dec 2022.