InterventionalNCT05336708
The Effect of Acupressure on Fatigue
A study testing Acupressure Group in people with Interventional, run by Mersin University at 2 sites in Turkey (Türkiye).
Trial summary
In this study, it is aimed to determine the effect of acupressure on fatigue in nursing students. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Interventional
- What is being tested?
- Acupressure Group
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 68 participants
- Where
- 2 sitesTurkey (Türkiye)
- Study dates
- 15 Sep 2021to 31 Dec 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Students studying at Mersin University Faculty of Nursing as 4th grade during the data collection date,
- Those who agree to participate in the study,
- No deformity or lesions in the areas where acupressure will be applied
- No acupressure experience
- No sleep disorder diagnosis and no medical treatment
- No diagnosis of anxiety disorder and no medical treatment No diagnosis of depression and no medical treatment
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- Coffee, cigarette and alcohol-free,
- No mental illness,
- Able to understand and speak Turkish and
- Those who signed the Informed Consent Form will be included in the study.
Who cannot join
- Students studying at Mersin University Faculty of Nursing outside the 4th grade during the data collection date,
- Those who do not agree to participate in the study,
- Those who have any deformity or lesion in the areas where acupressure will be applied
- Experienced with acupressure
- Diagnosed with sleep disorder and receiving medical treatment
- Diagnosed with anxiety disorder and receiving medical treatment
Show all 11Show fewer
- Diagnosed with depression and receiving medical treatment
- Coffee, cigarette and alcohol addiction,
- Having mental illness,
- who cannot understand or speak Turkish
- Those who do not sign the Informed Consent Form will not be included in the study.
Trial locations and contacts
2 sites in 1 country.
Turkey (Türkiye)2 sites
Mersin Üniversitesi
Mersin, Yenişehir, 33343
Mersin University Faculty of Nursing
Mersin, Yenişehir
About this study
Official title: The Effect of Acupressure on Fatigue in Nursing Students: A Randomized Controlled Study
In this study, it is aimed to determine the effect of acupressure on fatigue in nursing students.
Read the detailed description
In this study, 68 nursing students were randomly assigned to the acupressure and placebo (sham) acupressure groups. In the acupressure group (n=34), compression was applied to the 7th point of the heart meridian (HT7), the 4th point of the large intestine meridian (LI4), the 36th point of the stomach meridian (ST36), and the 6th point of the spleen meridian (SP6). Depending on the preparation and compression time at each point, the session duration of each student lasted an average of 20 minutes. In the sham group (n=34), pressure was applied approximately 1-1.5 cm away from the HT7, LI4, ST36, SP6 points. In the sham group, the acupressure application time lasted for an average of 20 minutes. At the end of the application, after the data collection process was completed, the sham group was taught the correct acupuncture points. Students applied acupressure three times a week for a total of 12 sessions for four weeks. Data were collected before and four weeks after the application in the acupressure and sham acupressure groups.
- Conditions
- Interventional
- Being tested
- Acupressure Group, Sham Acupressure Group
- Keywords
- Fatigue, Nursing students, Acupressure
- Medical subject headings
- Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Acupressure GroupOther
Also called Experimental Group
In the acupressure group, acupressure will be applied to the heart meridian 7th point (HT7), large intestine meridian 4th point (LI4), stomach meridian 36th point (ST36) and spleen meridian 6th point (SP6). After pressing each point for a certain period of time, a total of two minutes of rest periods will be applied by the researcher.
Sham Acupressure GroupOther
Also called Sham Group
In the sham acupressure group, acupressure will be applied on the bone region where the meridians do not pass, approximately 1-1.5 cm away from the HT7, LI4, ST36, SP6 points. The application process will continue in the same way with acupressure group and the pressure intensity will be less.
| Study group | Role | What they receive |
|---|---|---|
| Acupressure group | Experimental | The acupressure (experimental) group will apply acupressure to themselves three times a week for a total of 12 sessions for four weeks. Receives: Other: Acupressure Group |
| Sham Acupressure Group | Sham comparator | The sham acupressure group will apply acupressure to themselves three times a week for a total of 12 sessions for four weeks. Receives: Other: Sham Acupressure Group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fatigue evaluated using the Fatigue Severity Scale
It is a Likert-type scale consisting of a total of nine items, each item being evaluated between 1 and 7 (1=I totally disagree, 7=I totally agree). The fatigue score is obtained by dividing the total score obtained from the scale by the number of scale items. The score that can be obtained from the scale varies between 9 and 63. A high score indicates an increased level of fatigue.
Measured: Change from before implementation and 4th week of practice
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Apr 2022
- Study start15 Sep 2021
- Primary completion15 Sep 2021
- Study completion31 Dec 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for InterventionalStudies of the same condition, open and under way.
- More trials run by Mersin UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Prospective, parallel, two-arm, randomized controlled clinical trial
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 68 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mersin University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Esra Cavusoglu, Mersin University
- Investigators
- Meral Gün, Doctorate, Study director, Mersin University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05336708
- Sponsor's protocol ID
- MersinUu
- Status last verified
- Sep 2026
- First submitted
- 5 Apr 2022
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Acupressure on Fatigue in Nursing Students: A Randomized Controlled Study
- ClinicalTrials.gov ID
- NCT05336708
- Acronym / sponsor ID
- MersinUu
- Conditions
- Interventional
- Keywords
- Fatigue, Nursing students, Acupressure
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 68 participants (actual)
- Lead sponsor
- Mersin UniversityUniversity, hospital or other
- Study start
- 15 Sep 2021 (actual)
- Primary completion
- 15 Sep 2021 (actual)
- Study completion
- 31 Dec 2021 (actual)
- First posted
- 20 Apr 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In this study, it is aimed to determine the effect of acupressure on fatigue in nursing students.
Detailed description
In this study, 68 nursing students were randomly assigned to the acupressure and placebo (sham) acupressure groups. In the acupressure group (n=34), compression was applied to the 7th point of the heart meridian (HT7), the 4th point of the large intestine meridian (LI4), the 36th point of the stomach meridian (ST36), and the 6th point of the spleen meridian (SP6). Depending on the preparation and compression time at each point, the session duration of each student lasted an average of 20 minutes. In the sham group (n=34), pressure was applied approximately 1-1.5 cm away from the HT7, LI4, ST36, SP6 points. In the sham group, the acupressure application time lasted for an average of 20 minutes. At the end of the application, after the data collection process was completed, the sham group was taught the correct acupuncture points. Students applied acupressure three times a week for a total of 12 sessions for four weeks. Data were collected before and four weeks after the application in the acupressure and sham acupressure groups.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Prospective, parallel, two-arm, randomized controlled clinical trial
| Arm | Type | Receives |
|---|---|---|
| Acupressure group | Experimental | Other: Acupressure GroupThe acupressure (experimental) group will apply acupressure to themselves three times a week for a total of 12 sessions for four weeks. |
| Sham Acupressure Group | Sham comparator | Other: Sham Acupressure GroupThe sham acupressure group will apply acupressure to themselves three times a week for a total of 12 sessions for four weeks. |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (10 listed)
- Students studying at Mersin University Faculty of Nursing as 4th grade during the data collection date,
- Those who agree to participate in the study,
- No deformity or lesions in the areas where acupressure will be applied
- No acupressure experience
- No sleep disorder diagnosis and no medical treatment
Key exclusion criteria (11 listed)
- Students studying at Mersin University Faculty of Nursing outside the 4th grade during the data collection date,
- Those who do not agree to participate in the study,
- Those who have any deformity or lesion in the areas where acupressure will be applied
- Experienced with acupressure
- Diagnosed with sleep disorder and receiving medical treatment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Acupressure GroupAlso: Experimental GroupIn the acupressure group, acupressure will be applied to the heart meridian 7th point (HT7), large intestine meridian 4th point (LI4), stomach meridian 36th point (ST36) and spleen meridian 6th point (SP6). After pressing each point for a certain period of time, a total of two minutes of rest periods will be applied by the researcher. | Other | Acupressure group |
| Sham Acupressure GroupAlso: Sham GroupIn the sham acupressure group, acupressure will be applied on the bone region where the meridians do not pass, approximately 1-1.5 cm away from the HT7, LI4, ST36, SP6 points. The application process will continue in the same way with acupressure group and the pressure intensity will be less. | Other | Sham Acupressure Group |
Primary outcome
Fatigue evaluated using the Fatigue Severity Scale
Time frame: Change from before implementation and 4th week of practice
It is a Likert-type scale consisting of a total of nine items, each item being evaluated between 1 and 7 (1=I totally disagree, 7=I totally agree). The fatigue score is obtained by dividing the total score obtained from the scale by the number of scale items. The score that can be obtained from the scale varies between 9 and 63. A high score indicates an increased level of fatigue.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Meral Gün, Doctorate study director
Mersin University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Acupressure Group in people with Interventional, run by Mersin University at 2 sites in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 10 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fatigue evaluated using the Fatigue Severity Scale (time frame: Change from before implementation and 4th week of practice). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.