Clinical trials: Interventional
Hereditary Blood Disorders, Cardiovascular Diseases
Effect of mHealth Intervention on Oral Health-Related Quality of Life Among Adult Patients With Chronic Systemic Diseases
This study evaluated whether an mHealth oral health education intervention could improve oral health-related quality of life among adults with chronic systemic diseases registered in specialized disease centers in Al-Ahsa, Saudi…
- Conditions
- Hereditary Blood Disorders, Cardiovascular Diseases, Chronic Kidney Disease, Diabete Mellitus
- Trial name
- NCT07839429
- Testing
- mHealth Oral Health Education Intervention, Printed Oral Health Education Leaflet
- Where
- 4 sites in Saudi Arabia
- Volunteers
- 206 people
- Sponsor
- King Faisal University
Separation Anxiety Disorder, Generalized Anxiety Disorder
Modular Cognitive Behavioral Therapy for the Treatment of Child Anxiety Disorders in Elementary School Settings
Although cognitive behavioral therapy (CBT) has been found to be efficacious in the treatment of child anxiety disorders, little progress has been made in the dissemination of such treatments to real-world practice settings.
- Conditions
- Separation Anxiety Disorder, Generalized Anxiety Disorder, Social Phobia
- Trial name
- KATES (NCT00569829)
- Testing
- cognitive behavioral therapy
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Anesthesiology and Intensive Therapy Residents at the Faculty of Medicine, University of Indonesia
Effectiveness of Mindfulness Based Intervention in Reducing Stress Levels of Anesthesiology and Intensive Therapy Residents at the Faculty of Medicine, University of Indonesia
This study was conducted to determine the effectiveness of MBI technique in reducing the stress level of anesthesiology and intensive therapy residents at the Faculty of Medicine, University of Indonesia.
- Trial name
- NCT04279353
- Testing
- Mindfulness Based Intervention
- Where
- Indonesia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament (ACL) Reconstruction: Single Bundle Versus Double Bundle
ACL tear is a common injury among athletes. The recommended treatment includes reconstruction of the ligament. The common reconstruction technique is single bundle reconstruction.
- Trial name
- NCT01025895
- Testing
- acl reconstruction - double bundle technique, acle reconstruction - single bundle technique
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Pain, Postoperative, Surgical Procedures, Operative
Postoperative Pain in Adult Patients.
Each surgical intervention associated with even a minor tissue injury is a source of pain which needs to be effectively controlled.
- Trial name
- NCT03731039
- Testing
- Observational study
- Where
- Poland
- Volunteers
- 620 people
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Patient Readmission
Predicting Hospital Readmission for Surgical Patients Using Deep Learning Models With Smart Watch and Smart Ring Sensors Data
Hospital readmissions are an important measure of healthcare quality and safety. These events create a substantial burden for patients, families, and health systems because they may increase costs, extend recovery time, and lead…
- Trial name
- NCT07349901
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- Getúlio Vargas University Hospital
Spinal Cord Injuries
Multimodality Intervention for Function and Metabolism in SCI
The proposed phase 2 trial a randomized, placebo-controlled, parallel group trial in persons with cervical or thoracic SCI, AIS grade A, B, C, or D, 6 months or later after injury.
- Trial name
- NCT03576001
- Testing
- Testosterone Undecanoate, hybrid exercise
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Substance Abuse, HIV
Reducing High Risk Behavior in Treatment Court
This study will be the first to examine the efficacy of using a brief, computerized HIV risk reduction intervention in treatment courts.
- Trial name
- NCT01481428
- Testing
- Computer-facilitated HIV intervention, Attention Control
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Treatment Research Institute
Smoking Cessation
COVID-19 Brief Advice and Chat-based Support for Smoking Cessation Via "Quit to Win" Contest 2020
The present study will examine (1) the effectiveness of a combined brief advice and personalized chat-based support on COVID-19 related smoking messages and (2) explore the use of CBPR model to build capacity and to engage…
- Trial name
- QTW2020 (NCT04399967)
- Testing
- Chat-based support, AWARD plus COVID-specific advice, AWARD advice
- Where
- China
- Volunteers
- 1,166 people
- Sponsor
- The University of Hong Kong
Anxiety, Stress
A New Mindfulness Intervention Called Mindfulness Based Swinging Technique (MBST) for Women With Breast Cancer
It is hypothesised to find that the new mindfulness intervention of Mindfulness Based Swinging Technique (MBST) for Women With Breast Cancer is an effective therapeutic intervention to be applied in breast cancer population.
- Conditions
- Anxiety, Stress, Self Efficacy, Depression
- Trial name
- NCT03985267
- Testing
- Mindfulness based Swinging Effect Intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- University of Barcelona
Osteopenia, Osteoporosis
Food Trial Evaluating Fecal Abundance of SBD111 With Once-Daily Versus Twice-Daily Administration in Healthy Adults
The purpose of this study is to determine whether a modified formulation and daily intake schedule of SBD111 results in similar levels of probiotic microbes in the gut compared with the currently used formulation.
- Conditions
- Osteopenia, Osteoporosis, Menopause Related Conditions, Probiotic Intervention
- Trial name
- NCT07538167
- Testing
- SBD111(current formulation), SBD111 (new formulation)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Solarea Bio, Inc
Breast Cancer, Fear of Cancer
Targeted eHealth Intervention to Reduce Fear of Recurrence Among Breast Cancer Survivors
The FoRtitude trial aims to evaluate an eHealth intervention designed to teach breast cancer survivors strategies to manage anxiety about cancer recurrence.
- Trial name
- FoRtitude (NCT03384992)
- Testing
- Diaphragmatic breathing and relaxation, Cognitive restructuring, Scheduled worry practice
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Preterm Birth
E-health-supported Diagnostic and Intervention in Preterm Born Children and Their Families
The app-based diagnostic and support approach with a focus on mental and somatic symptoms is intended to strengthen the resilience of premature born children and families and to identify risk and resilience factors.The overall…
- Trial name
- NeoUp2 (NCT06939192)
- Testing
- Intervention Group (APP), Treatment as usual-Group (TAU)
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer
The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients
The study was designed as a prospective, observational study. Pediatric patients under 18 years of age scheduled for peripheral vascular access placement during day-case surgery or non-operating room anesthesia (NORA) will be…
- Conditions
- Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer, Cataract, Crohn's Disease
- Trial name
- NCT07315711
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sibel Seçkin Pehlivan
Internet-based Intervention, Depression
Treatment Outcomes and Predictive Factors of the Effectiveness and Adherence of Moodpep: an Online Self-help Intervention for College Students With Depressive Symptoms
Depressive symptoms are prevalent among college students and often remain untreated. E-health interventions may help overcome treatment barriers by offering accessible and flexible support.
- Conditions
- Internet-based Intervention, Depression, Adherence, Predictors
- Trial name
- NCT07030244
- Testing
- Moodpep
- Where
- 2 sites in Netherlands
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Substance Abuse, Intimate Partner Violence (IPV)
SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Families
This study aims to prevent syndemic health conditions by decreasing acculturative stress and promoting resilience via SER Familia (Salud, Estrés y Resilencia en Familias/ Health, Stress, and Resilience in Families), a…
- Conditions
- Substance Abuse, Intimate Partner Violence (IPV), HIV Infections, Depression
- Trial name
- SER Familia (NCT06627764)
- Testing
- SER Familia
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Duke University
Esophageal Cancer, Gastroesophageal Junction Cancer
Retrospective Evaluation of Nivolumab in Adjuvant Esophageal Cancer/Gastroesophageal Junction Cancer
The purpose of this study is to describe the real-world effectiveness and patterns of use of adjuvant nivolumab in adult participants with Stage II/III Esophageal Cancer/Gastroesophageal Junction Cancer (EC/GEJC) in China.
- Trial name
- NCT06499298
- Testing
- Nivolumab
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Bristol-Myers Squibb
Abdominal Aortic Aneurysm (AAA)
Endovascular Aneurysm Repair (EVAR) Gate Study
This study will evaluate a randomized comparison of direct versus snare techniques for cannulation of contralateral gate during an endovascular aneurysm repair (EVAR) procedure.
- Trial name
- EVAR (NCT02934087)
- Testing
- Endovascular Aneurysm Repair
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Minneapolis Heart Institute Foundation
Lung Cancer
The Role of Interventional Pulmonology, Microbiota and Immune Response in the Patient With Lung Cancer
This study is designed to evaluate complications, specificity, diagnostic yield of radial endobronchial ultrasound guided transbronchial cryobiopsy and transbronchial forceps biopsy with fluoroscopy in the diagnosis of peripheral…
- Trial name
- RIPMIRLC (NCT05164445)
- Testing
- Transbronchial forceps biopsy, Transbronchial forceps biopsy+Transbronchial cryobiopsy
- Where
- Lithuania
- Volunteers
- 200 people
- Sponsor
- Lithuanian University of Health Sciences
Ovary Cancer
Olaparib Real-world Utilization and Clinical Outcomes in France, Italy, and the UK
This is a retrospective observational medical records review study of BRCA mutated advanced (FIGO stage III-IV) ovarian cancer patients who received first dose maintenance olaparib in 1L setting in France, Italy and the UK.
- Trial name
- OVAL-1 (NCT04532645)
- Testing
- Olaparib
- Where
- 55 sites in France, Italy and 1 more
- Volunteers
- 342 people
- Sponsor
- AstraZeneca
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