MagnesiumMG-MCP2022NCT05339308
Effects of Magnesium Oil Application on the Muscle Contractile Properties
A study testing Magnesium oil (BetterYou) dermal application in people with Magnesium and Skeletal Muscle Contraction Properties, run by University of Ljubljana at 2 sites in 2 countries.
Trial summary
This study will aim to investigate the effects of magnesium oil administration on skeletal muscle contractile properties. Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Magnesium, Skeletal Muscle Contraction Properties
- What is being tested?
- Magnesium oil (BetterYou) dermal application
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 18 participants
- Where
- 2 sitesin 2 countries
- Study dates
- 1 May 2022to 1 Sep 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- healthy, recreationally active adults, no history of neuromuscular and musculoskeletal diseases
Who cannot join
- if some of the criteria are not met
Trial locations and contacts
2 sites in 2 countries.
2 sites in 2 countries
About this study
This study will aim to investigate the effects of magnesium oil administration on skeletal muscle contractile properties.
Read the detailed description
Aim: This study will aim to investigate the effects of magnesium oil administration on skeletal muscle contractile properties (SMcp).
Design: Randomized controlled study
Participants: For this purpose, investigators will recruit 40 recreationally active and healthy adults of both sexes (18-35 years of age).
Methods: The experimental leg (EXP) will receive the 10 sprays of magnesium oil (20 mg per spray) that will be topically applied to the skin covering the knee extensor muscles, whereas the control leg (CON) will receive 10 sprays of natural mineral-free oil. The vastus lateralis SMcp will be measured by using a tensiomyography (TMG) device before application (PRE) and after 10 (POST10), 20 (POST20), 30 (POST30), 40 (POST40), and 50 (POST50) minutes of application onset, respectively.
- Conditions
- Magnesium, Skeletal Muscle Contraction Properties
- Being tested
- Magnesium oil (BetterYou) dermal application, Placebo Control
- Keywords
- Tensiomyography, Skeletal Muscle, Contractile Properties
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Magnesium oil (BetterYou) dermal applicationOther
10 sprays (200 mg) of magnesium oil (BetterYou) will be applied to skin covering knee extensor muscles. The magnesium oil will be applied only once
Placebo ControlOther
Also called CONTROL
Natural mineral-free oil (10 sprays) will be applied as the control condition. This will be done only once
| Study group | Role | What they receive |
|---|---|---|
| Experimental | Experimental | Magnesium oil application Receives: Other: Magnesium oil (BetterYou) dermal application |
| Control | Placebo comparator | Natural mineral-free oil application Receives: Other: Placebo Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Skeletal Muscle Contractile Properties
Skeletal muscle contractile properties will be measured by using tensiomyography device
Measured: 75 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Apr 2022
- Study start1 May 2022
- Primary completion1 Aug 2022
- Study completion1 Sep 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for MagnesiumStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized controlled study
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 18 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Ljubljana
- Sponsor type
- University, hospital or other
- Collaborators
- Masaryk University
- Responsible party
- Principal investigator, Armin Paravlic, University of Ljubljana
- Investigators
- Armin Paravlic, PhD, Principal investigator, Faculty of Sport
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05339308
- Sponsor's protocol ID
- MG-MCP2022
- Acronym
- MG-MCP2022
- Status last verified
- Nov 2024
- First submitted
- 14 Apr 2022
- Last updated
- 18 Nov 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Nov 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Magnesium Oil Application on the Muscle Contractile Properties
- ClinicalTrials.gov ID
- NCT05339308
- Acronym / sponsor ID
- MG-MCP2022 / MG-MCP2022
- Conditions
- Magnesium, Skeletal Muscle Contraction Properties
- Keywords
- Tensiomyography, Skeletal Muscle, Contractile Properties
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 18 participants (actual)
- Lead sponsor
- University of LjubljanaUniversity, hospital or other
- Collaborators
- Masaryk University
- Study start
- 1 May 2022 (actual)
- Primary completion
- 1 Aug 2022 (actual)
- Study completion
- 1 Sep 2022 (actual)
- First posted
- 21 Apr 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will aim to investigate the effects of magnesium oil administration on skeletal muscle contractile properties.
Detailed description
Aim: This study will aim to investigate the effects of magnesium oil administration on skeletal muscle contractile properties (SMcp).
Design: Randomized controlled study
Participants: For this purpose, investigators will recruit 40 recreationally active and healthy adults of both sexes (18-35 years of age).
Methods: The experimental leg (EXP) will receive the 10 sprays of magnesium oil (20 mg per spray) that will be topically applied to the skin covering the knee extensor muscles, whereas the control leg (CON) will receive 10 sprays of natural mineral-free oil. The vastus lateralis SMcp will be measured by using a tensiomyography (TMG) device before application (PRE) and after 10 (POST10), 20 (POST20), 30 (POST30), 40 (POST40), and 50 (POST50) minutes of application onset, respectively.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- Randomized controlled study
| Arm | Type | Receives |
|---|---|---|
| Experimental | Experimental | Other: Magnesium oil (BetterYou) dermal applicationMagnesium oil application |
| Control | Placebo comparator | Other: Placebo ControlNatural mineral-free oil application |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- healthy, recreationally active adults, no history of neuromuscular and musculoskeletal diseases
Key exclusion criteria (1 listed)
- if some of the criteria are not met
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Magnesium oil (BetterYou) dermal application10 sprays (200 mg) of magnesium oil (BetterYou) will be applied to skin covering knee extensor muscles. The magnesium oil will be applied only once | Other | Experimental |
| Placebo ControlAlso: CONTROLNatural mineral-free oil (10 sprays) will be applied as the control condition. This will be done only once | Other | Control |
Primary outcome
Skeletal Muscle Contractile Properties
Time frame: 75 minutes
Skeletal muscle contractile properties will be measured by using tensiomyography device
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Nov 2024.
- Individual participant dataSharing planned: No
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Magnesium Sulphate as an Adjuvant in Combined Costoclavicular Block and Suprascapular Block Versus Interscalene Block for Ambulatory Shoulder Arthroscopy
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The Effect of Magnesium on Post-spinal Headaches
Post-spinal Headache
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Armin Paravlic, PhD principal investigator
Faculty of Sport
2 sites in 2 countries: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Magnesium oil (BetterYou) dermal application in people with Magnesium and Skeletal Muscle Contraction Properties, run by University of Ljubljana at 2 sites in 2 countries.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Nov 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Czechia, Slovenia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Skeletal Muscle Contractile Properties (time frame: 75 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Nov 2024.