AzTrials
AzTrials

Heart FailureNCT05350202

Emp-Activity: Empagliflozin Functional Capacity

An observational study of Heart Failure, run by Boehringer Ingelheim at 350 sites in 6 countries.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

This is a multinational non-interventional study based on newly collected data to assess demographics, disease, and treatment pattern of patients with chronic Heart Failure (HF) in a two-cohort design: one cohort will receive first prescription of empagliflozin as routine therapy for HF, the other cohort will receive… Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Heart Failure
What is being tested?
Empagliflozin
How many people
3,431 participants
Where
350 sitesin 6 countries
Study dates
18 Dec 2022to 25 Jul 2024
Phase
Observational
Are there results?
Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: Patients with chronic Heart Failure (HF) in a two cohort design: one cohort will receive first prescription of empagliflozin as routine therapy for HF, the other cohort will receive HF therapy with drugs with another mechanism of action.

Who may be able to join

  • Written informed consent prior to study participation
  • Male and female patients ≥ 18 years at Visit 1
  • Patients must be contractually capable and mentally able to understand and follow the instructions of the study personnel
  • Patients with diagnosis of chronic heart failure NYHA Class 2-4
  • Treatment-naïve for SGLT2i at visit 1
  • Women of childbearing potential must take appropriate precautions against getting pregnant according to approval of chosen HF drug(s)

Who cannot join

  • Missing physician's diagnosis of chronic heart failure
  • Patients hospitalized at visit 1
  • Life expectancy ≤ 12 months according to physician's assessment
  • Lack of informed consent
  • Pregnant or lactating females
  • Participation in a parallel interventional clinical trial
Show all 11Show fewer
  • Chosen treatment with another SGLT2i drug than empagliflozin
  • Having been enrolled into the non-empagliflozin-arm of this non-interventional study
  • Current or prior treatment with SGLT2i at visit 1
  • Patients with contraindications according to current Summary of Product Characteristics (SmPC)
  • Patients with dependency or relationship to the treating physician

Trial locations and contacts

350 sites in 6 countries.

350 sites in 6 countries

Poland115 sites

  • ECHOKardio Poradnia Kardiologiczna

    Bialystok, 15-028

  • Klinika Kardiologii Uniwersyteckiego Szpitala Klinicznego w Białymstoku

    Bialystok, 15-276

  • Kardiologiczna Praktyka Lekarska Anna Tomaszuk-Kazberuk

    Bialystok, 15-546

  • Podlaski Ośrodek Kardiologii

    Bialystok, 15-875

  • Specjalistyczna Praktyka Lekarska Marek Styczkiewicz

    Brzozów, 36-200

  • BlueMed - Centrum Medyczne

    Bydgoszcz, 85-088

  • Centrum Kardiologii Paweł Grzelakowski

    Bydgoszcz, 85-095

  • Centrum Medyczne A i D Nowak sj

    Bydgoszcz, 85-314

  • Indywidualna Specjalistyczna Praktyka Lekarska Tomasz Ługowski

    Bydgoszcz, 85-791

  • Specjalistyczna Praktyka Lekarska Grzegorz Grześk

    Bydgoszcz, 85-796

  • Indywidualna Specjalistyczna Praktyka Lekarska Jolanta Nowak

    Bytom, 41-902

  • Specjalistyczna Praktyka Lekarska Agata Fenger

    Chorozow, 41500

  • Med. - Zone sp zoo

    Cieszyn, 43-400

  • Specjalistyczna Praktyka Lekarska lek.n.med.Lucyna Góras-Hetmańczyk

    Czeladź, 41250

  • Gabinet Kardiologiczny - Jacek Jafra

    Częstochowa, 42-202

  • Prywatna Praktyka Lekarska Artur Dekiela

    Częstochowa, 42-202

  • Specjalistyczna Praktyka Lekarska Magdalena Miczko

    Dąbrowa Górnicza, 41-300

  • ISPL Małgorzata Dobrowolska Gabinet Tendo

    Gdynia, 81-395

  • Specjalistyczna Praktyka Lekarska Wojciech Czapla

    Gliwice, 44-100

  • Miedziowe Centrum Zdrowia S.A.

    Głogów, 67-200

  • Centrum Medyczne NIWA

    Głogów Małopolski, 36-060

  • Dorota Adamczyk-Kot NZOZ-KARDIO

    Gmina Jędrzejów, 28-300

  • Lekarze na Dworskiej

    Gmina Świebodzin, 66-200

  • Indywidualna Praktyka Lekarska Tomasz Zieliński

    Grodzisk Mazowiecki, 05-825

  • Przychodnia Lekarska Zdrowy Miś

    Grójec, 05-600

  • Indywidualna Praktyka Lekarska Piotr Tokarczyk

    Inowrocław, 88-100

  • Familia Medicina Sp. z o.o.

    Iwanowice Włościańskie, 32-095

  • Specjalistyczna Praktyka Lekarska Jarosław Paździerz

    Jasło, 38-200

  • Specjalistyczna Praktyka Lekarska Urszula Winiarska-Waluś

    Jastrzębie Zdrój, 44-330

  • Centrum Medyczne Kinesis

    Kamień, 36-053

  • Praktyka Lekarska Wojciech Kwaśniewski

    Katowice, 40-645

  • Prywatna Przychodnia Specjalistyczna Drozd Zbigniew Gąsior

    Katowice, ul. Drozdów 26

  • CUM PromontMed

    Kielce, 25-020

  • Arsmedica Specjalistyczna Praktyka Lekarska lek.med. Krzysztof Czerniejewski

    Konin, 62-500

  • Prywatny Gabinet Kardiologiczny lek. med. Sławomir Kępski

    Konin, 62-500

  • Specjalistyczna Praktyka Lekarska Paweł Michalski

    Konin, 62-500

  • Uromed Sp Zoo

    Koszalin, 75-402

  • Poliklinika MSWiA/Indywidualna Specjalistyczna Praktyka Lekarska Krzysztof Jarząbek

    Koszalin, 75-604

  • Indywidualna Praktyka Lekarska Krzysztof Maślak

    Koźminek, 62-840

  • Centrum Medyczne Dietla 19 sp. Z o.o.

    Krakow, 31-070

  • Centrum Twojego Zdrowia

    Krakow, 31-101

  • Specjalistyczna Praktyka Lekarska "Kardiolek" Dr med. Piotr Wilkołek

    Krakow, 31-216

  • CM Oficerskie

    Krakow, 31-513

  • Poradnia Kardiologiczna, Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie

    Krakow, 31-826

  • Prywatny Gabinet Kardiologiczny Dr n.med Janusz Bąk

    Kranse, 36-007

  • Centrum Medyczne Dębina

    Krościenko Wyżne, 38-422

  • Poradnia Kardiologiczna Centrum Medyczne w Łańcucie

    Łańcut, 37-100

  • SP ZOZ Łęczna

    Łęczna, 21-010

  • Beata Mikłaszewicz&Dariusz Dąbrowski Cardiamed S.J.

    Legnica, 59-220

  • NZOZ DUOMED S.C. Poradnia Kardiologiczna

    Legnica, 59-220

  • Prywatny Specjalistyczny Gabinet Kardiologiczno-Internistyczny

    Libiąż, 32-590

  • Santa Sp. z o.o.

    Lodz, 90-302

  • Nzoz Salusmed

    Lodz, 91-002

  • Kardiologiczna Praktyka Lekarska Wojciech Kula

    Lublin, 20-053

  • NZOZ Sanus Jacek Madej Poradnia kardiologiczna

    Lublin, 20-143

  • NZOZ Sanus Jacek Madej

    Lublin, 20-143

  • Provivo Specjalistyczne Centrum Medyczne

    Lublin, 20-400

  • Indywidualna Specjalistyczna Praktyka Lekarska - Renata Leniec

    Lublin, 59-300

  • Kardiologiczno - Internistyczny Gabinet Lekarski Skrzyński Andrzej

    Łuków, 21-400

  • Niepubliczny Zakład Opieki Zdrowotnej Specjalistyczne Gabinety lekarskie

    Mikołów, 43-190

  • Gabinet Lekarski Kardiologiczny

    Mirków, 55-095

  • Prywatne Usługi Medyczne Jacek Morka

    Modliszewice, 26-200

  • Indywidualna Specjalistyczna PraktyKa Lekarska-Piotr Utz

    Moszczenica, 97-310

  • Gabinet Lekarski Ewa Burchard

    Nowe Miasto nad Pilicą, 26-420

  • Medyczne Centrum Zdrovita

    Nowy Tomyśl, 64-300

  • Oleśnica Prywatna Praktyka Lekarska

    Oleśnica, 56-400

  • SZOZ Jantar Sp. z o.o. Poradnia Lekarzy Specjalistów

    Ostrów Wielkopolski, 63-400

  • GVM CARINT Oświęcim

    Oświęcim, 32-600

  • Specjalistyczna Praktyka Lekarska Rafał Nowak

    Piasek, 43-211

  • Specjalistyczna Praktyka Lekarska Andrzej Bęben

    Piotrkow Trybunalski, 97-300

  • Indywidualna Specjalistyczna Praktyka Lekarska Maciej Strawczyński

    Płock, 09-402

  • Indywidualna Specjalistyczna Praktyka Lekarska Andrzej Bolewski

    Poznan, 60-461

  • Wojewódzki Szpital im. św. Ojca Pio w Przemyślu

    Przemyśl, 37-700

  • Leszek Kaminski Specjalistyczny Gabinet Lekarski

    Przeworsk, 37-200

  • Praktyka Lekarska Katarzyna Czarnecka

    Pszczyna, 43-200

  • PCK - Puławskie Centrum Kardiologiczne Przychodnia Specjalistyczna

    Puławy, 24-100

  • Poradnia Kardiologiczna SPZOZ Pulawy

    Puławy, 24-100

  • Indywidualna Specjalistyczna Praktyka Lekarska Magdalena Poterala

    Radom, 26-600

  • Poradnia Kardioogiczna Zegara Słonecznego

    Radom, 26-600

  • Specjalistyczna Praktyka Lekarska Radzionków

    Radzionków, 41-922

  • Indywidualna Specjalistyczna Praktyka Lekarska dr n. med. Alicja Gałuszka-Bilińska

    Rybnik, 44-203

  • Specjalistyczna Praktyka Lekarska Wiesława Faberska-Blicharska

    Rybnik, 44-217

  • Centrum Medyczne Sabamed

    Rzeszów, 35-006

  • Prywatny Gabinet Kardiologiczny dr n.med Janusz Romanek

    Rzeszów, 35-055

  • My Life Centrum chorób serca

    Sanok, 38-500

  • Specjalistyczna Praktyka Lekarska Kamila Stembalska

    Ścinawa, 59-330

  • Monika Kujawiak Prywatna Praktyka Lekarska

    Siedlce, 08-110

  • Prywatny Gabinet Lekarski Hanna Wilk-Manowiec

    Siedlce, 08-110

  • Indywidualna praktyka lekarska Artur Marcinkiewicz

    Siemianowice Śląskie, 41-106

  • Asnyka 78d Gabinety Lekarskie

    Skierniewice, 96-100

  • Specjalistyczna Praktyka Lekarska Maciej Kaźmierski

    Sosnowiec, 41-200

  • Specjalistyczna Praktyka Lekarska Marek Kondys

    Sosnowiec, 41-200

  • Powiatowy Szpital Specjalistyczny w Stalowej Woli

    Stalowa Wola, 37-450

  • Centrum Medyczne VITA

    Szczecin, 70-341

  • Specjalistyczna Praktyka Lekarska Tomasz Urbanik

    Szczecin, 71-790

  • ISPL Anna Bis

    Szczecin, 71-804

  • Szpital w Szczecinku

    Szczecinek, 78-400

  • Gabinet Lekarski Weronika Greberska

    Szczytniki, 62-023

  • Specjalistyczna Praktyka Lekarska Paweł Kocik

    Tarnów, 33-100

  • Leomed Centrum Medyczne

    Tarnowskie Góry, 42-606

  • Prywatna Praktyka Lekarska na wezwanie Mirosław Marciniak

    Torun, 87-100

  • Indywidualna Specjalistyczna Praktyka Lekarska - Witold Orszulak

    Tychy, 43-100

  • Urszula Urbanowicz Specjalistyczna Praktyka Lekarska

    Tychy, 43100

  • Centrum Medyczne Nowe Miasto

    Wałbrzych, 58-302

  • SERCE S.C. Przychodnia Lekarzy Specjalistów

    Warsaw, 02-496

  • Klinika 37 Centrum Kardiologii Płowiecka

    Warsaw, 02-991

  • Prywatny Gabinet Lekarski Bożena Norwa-Otto

    Warsaw, 04-188

  • Gabinet Lekarski lek med. Robert Włodarczyk

    Wawrzeńczyce, 32-125

  • Specjalistyczny Gabinet Lekarski Łukasz Graczykowski

    Włocławek, 87-800

  • Specjalistyczna Prajtyka Lekarska Grażyna Glanowska

    Zabrze, 10444

  • Gabinet Prywatnej Praktyki Lekarskiej Kard.-Int . Dr n.med. Brygida Przywara-Chowaniec

    Zabrze, 41-800

  • Ns Zoz Kardiologia Sp. Z.O.O.

    Zamość, 22-400

  • Gabinety Lekarskie JM Kulczyccy

    Żary, 68-200

  • ALDEMED Centrum Medyczne

    Zielona Góra, 65-001

  • Prywatna Praktyka Lekarska Anna Chudoba

    Żyrardów, 96-300

Other trials in Poland

Romania106 sites

  • Miclea Ioana - Mariana MEDIC SPECIALIST CARDIOLOG

    Alba Iulia, 510137

  • Dr. Morar Mihnea-Dragoscabinet Medical Individual - Specialist Cardiologie

    Arad, 310009

  • Dr. Pop-Moldovan Adina-Ligia - Medicina Interna - Cardiologie

    Arad, 310182

  • CMI Iosipescu Laura Cristina

    Bacau, 600037

  • Cardio Animus SRL

    Bacau, 600204

  • CMI - Centrul medical Diacord

    Baia Mare, 430076

  • Mercea Corina-Delia - Medic

    Baia Mare, 430123

  • Ambrinomed SRL

    Botoșani, 710095

  • Cardioland SRL

    Brasov, 500326

  • Rus V. Horatiu - Cabinet Medical Individual de Cardiologie

    Brasov, RO-500188

  • S.C. Ilro Medical S.R.L

    Bucharest, 010991

  • PFA Balahura Cristian

    Bucharest, 011026

  • Dr. Danet Ruxandra - Medic Cardiologie

    Bucharest, 011258

  • Dr. Bogdan Stefan Nicolae

    Bucharest, 011925

  • Cardiocare Center SRL

    Bucharest, 012052

  • Cordmedica SRL

    Bucharest, 012082

  • Dr. Serban Irina-Ruxandra - MEDIC PRIMAR CARDIOLOGIE

    Bucharest, 020281

  • Urocard Plus Srl

    Bucharest, 020281

  • Medi Pro Consult SRL

    Bucharest, 020501

  • Cmi Dr Georgescu Dragos

    Bucharest, 021705

  • Dr. Geavlete Dana-Oliviana - Activitate Medicala

    Bucharest, 021967

  • Mihaila I. Sorina - Medic Pfi

    Bucharest, 030915

  • S.C. Cardiomedical Team Pro S.R.L.

    Bucharest, 040343

  • Dumitrescu Silviu-Ionel Persoana Fizica Autorizata

    Bucharest, 060926

  • Mihalcea Janina-Diana Medic Specialist Cardiologie

    Bucharest, 061192

  • Patrascu R. Natalia - Medic Specialist Medicina Interna

    Bucharest, 061304

  • Popescu I. Ileana Nicoleta Medic specialist cardiologie

    Bucharest, 061406

  • CMI Dr. Parsa Motlagh Babak

    Bucharest, 062282

  • Magister Research SRL

    Bucharest, 070000

  • Dr. Lungeanu-Juravle Laura-Activitate Medicala

    Bucharest, RO-011038

  • Cardio Clinique NCS SRL

    Buzău, 120195

  • Medcon SRL

    Buzău, 120203

  • Medicard SRL

    Buzău, 120279

  • Angioplast Medical srl

    Ciurea, RO-707085

  • CMI Diaconescu Iulia Dana

    Cluj-Napoca, 400347

  • Mediprax Centrum Cluj Napoca

    Cluj-Napoca, 400347

  • SC Adisan SRL

    Cluj-Napoca, 400347

  • Sc Medicardio Andreea Srl

    Cluj-Napoca, 400347

  • Cardiotreat SRL

    Cluj-Napoca, 400349

  • SC Clujana Medica Srl

    Cluj-Napoca, 400394

  • PFA Comsa M.Dan-Horatiu

    Cluj-Napoca, 400441

  • Cabinet Cardiohealt Srl

    Cluj-Napoca, 400479

  • SC Cardioprotect MED SRL

    Cluj-Napoca, 400535

  • Sc Dentcor Srl

    Cluj-Napoca, RO-400480

  • Cardio World Health

    Com Mosoaia, 117512

  • Cardio Manea Adelina SRL

    Constanța, 610219

  • Endodiahealth Srl

    Constanța, 900002

  • Dr. Maxim George Razvan - Activitate Medicala

    Constanța, 900168

  • CMI Dr Ilie Ivona Valeria

    Constanța, 900519

  • Asclepios Medicalhealth SRL

    Constanța, 900615

  • Sc Daxiela Impex Srl

    Craiova, 200085

  • Hortopan Med SRL

    Craiova, 200323

  • Neurocord Medical Srl

    Craiova, 200383

  • Vesalius Medical S.R.L

    Craiova, 200470

  • Cabinet Medical Individual - Dr. Popescu Monica

    Craiova, 200519

  • SC A&C Medical Prime SRL

    Craiova, RO-200692

  • S & R Cardiobalance Srl

    Curtea de Argeş, 115300

  • Cardiolife

    Deva, 330011

  • Bendl H. Laura Elena - Cabinet Medical Individual Plus Clinic

    Drobeta-Turnu Severin, 220004

  • SC Maycor SRL

    Galati, 800217

  • CMI Dr. Chiscaneanu Teodor

    Galati, 800584

  • Cardiomedplus SRL

    Gheorghieni, 535500

  • Procardia Serv-Med 2009 SRL srl

    Iași, 700111

  • Sc Cardiocare Clinic Srl

    Iași, 700260

  • Sc Cardiortomed Srl

    Iași, 700282

  • Medical Cardio Anghel SRL

    Iași, 700451

  • Niculescu G. Ana Irina - Medic colaborator

    Iași, 700688

  • SC Cardiomed SRL Iasi

    Iași, 700732

  • Cardioszakacs Srl, Cui 34404518

    Miercurea-Ciuc, 530112

  • Polimed Center SRL, CUI 26072639

    Odorheiu Secuiesc, 535600

  • CMI Dr. Rotariu Dragos

    Oradea, 410009

  • CMI Societatea civila Magheru&Magheru

    Oradea, 410027

  • CMI Cardiomed SRL

    Oradea, 410169

  • PFA Dr. Ardelean Adriana Ioana

    Oradea, 410388

  • Dradiand SRL

    Oradea, 410473

  • Sc Adriacard Srl

    Oradea, 410474

  • Simed Concept SRL

    Ostratu, 012052

  • Andries I. Elena - Medic Primar Cardiologie Si Medic Specialist Mi

    Piatra Neamţ, 610065

  • Cardiomed Alexandrescu Srl-D

    Piatra Neamţ, 610078

  • Dr. Corcoz Cardiologie SRL

    Piatra Neamţ, 610150

  • Davisof San Srl

    Piteşti, 110003

  • Clinica Cardiologie Dr Stanciu Viorel

    Piteşti, 110074

  • Sc Procordia Concept Srl

    Piteşti, 110172

  • Cavi Clinique SRL

    Ploieşti, 100562

  • SC Cardiologie Dr. Cristina Radoi SRL

    Râmnicu Vâlcea, 240022

  • Sc Lidermed Plus Srl

    Râmnicu Vâlcea, 240282

  • Sc Incarmed Srl

    Râmnicu Vâlcea, 240284

  • Gx.Hatconsulting Srl

    Săcele, 505600

  • Cardio Stim Center SRL

    Sânpetru, 507190

  • Munteanu Alice-Elena - Medic Cardiolog

    Sat Rosu, Comuna Chiajna, 077041

  • Voineag Olivia Medic Colaborator

    Scheia, 720282

  • Batar D. Sergiu Constantin

    Şelimbăr, 557260

  • SC Endocordis SRL

    Sfântu Gheorghe, 520068

  • Rusu N. Ramona Iulia Medic Primar Cardiologie

    Suceava, 720067

  • German Sallo Marta - Medic primar cardiolog, CIF 35699735

    Târgu Mureş, 540095

  • CMI Tatar A. Maria Cristina, CUI 19814204

    Târgu Mureş, RO-540496

  • Diaconu Diana - Medic Cif 31885867

    Tifgu Mures, 540281

  • Cardiomed Health SRL

    Timișoara, 300172

  • Mornos Cristian Medic Independent

    Timișoara, 300230

  • Cardio Suport SRL

    Timișoara, 300244

  • Medicalife Tim SRL

    Timișoara, 300362

  • Cardio - DRS S.R.L

    Timișoara, 300369

  • Policlinica Dr. Tudoran

    Timișoara, 300480

  • Croitoru G Rodica Medic Colaborator

    Valea Adâncă, 700732

  • CMI Demle S. Adriana-Cristina

    Zalău, 450103

  • Dr. Dragos Lupu - Medic Specialist Cardiolog

    Zarnesti, 505800

Other trials in Romania

Czechia41 sites

  • MUDr. Hana Burianová

    Bílovec, 743 01

  • Fakultní nemocnice u sv. Anny v Brně

    Brno, 602 00

  • MUDr. Karel Kameník s.r.o.

    Brno, 603 00

  • MUDr. Libor Nechvátal s.r.o.

    Brno, 61600

  • Zdravá srdce s.r.o.

    Brno, 62700

  • Kardiologická ambulance Brno, s.r.o.

    Brno-Královo Pole, 61200

  • EDUMED s.r.o. - Dr. Nováková

    Broumov, 55001

  • EDUMED s.r.o. - Dr. Polášková

    Broumov, 55001

  • EDUMED s.r.o. - Dr. Švarcová

    Broumov, 55001

  • EDUMED s.r.o.

    Broumov, 55001

  • Kardiologická ambulance Český krumlov

    Český Krumlov, 38101

  • CorMedico s.r.o.

    Frýdek-Místek, 73801

  • DIKa centrum s.r.o.

    Havířov, 73601

  • Lékařský servis, a.s.

    Havířov, 73601

  • Kardio Pudich s.r.o.

    Hlučín, 748 01

  • ProKardio HK, s.r.o.

    Hradec Králové, 50011

  • Nemocnice Jihlava - Kardiologické oddělení

    Jihlava, 58633

  • Oblastní nemocnice Kolín, a.s. nemocnice Středočeského kraje

    Kolín, 2802

  • KardioBušák s.r.o.

    Louny, 440 01

  • Kardiomost s.r.o.

    Most, 43401

  • Nemocnice AGEL Nový Jičín, a.s.

    Nový Jičín, 74101

  • Kardiologická ambulance Olomouc

    Olomouc, 77900

  • Nemocnice AGEL Ostrava-Vítkovice a.s. - Kardiologická ambulance

    Ostrava, 70030

  • Kardiologická ambulance Mammed

    Ostrava, 70200

  • OVAKARD s.r.o.

    Ostrava, 70200

  • Poliklinika Nová Huť

    Ostrava, 71900

  • Fakultní nemocnice Ostrava

    Ostrava - Poruba, 708 52

  • Kardiologie Vinohrady s.r.o.

    Prague, 120 00

  • Kardiologie prof. Táborský s.r.o.

    Prague, 12000

  • Vseobecna fakultni nemocnice v Praze

    Prague, 128 00

  • MEDICON a.s.

    Prague, 140 00

  • Nemocnice na Homolce

    Prague, 150 30

  • Clinical Trials Service s.r.o.

    Prague, 15600

  • ROcardia s.r.o.

    Prostějov, 79604

  • Galenica Medical s.r.o.

    Prostřední Suchá, 73564

  • KARDIO GRÉZL, s.r.o.

    Šumperk, 78701

  • Všeobecná interní ambulance s.r.o.

    Tábor, 39003

  • Nemocnice AGEL Třinec-Podlesí a.s.

    Třinec Podlesí, 73961

  • Kardiologická ambulance MUDr. Ferkl s.r.o.

    Trutnov, 54101

  • Lunacor s.r.o.

    Vizovice, 76312

  • Krajská nemocnice T. Bati, a.s.

    Zlín, 76275

Other trials in Czechia

Switzerland40 sites

  • Universitätsspital Basel

    Basel, 4051

  • Spital Sonnenhof

    Bern, 3006

  • Engeried-Spital (Bern)

    Bern, 3012

  • Spitalzentrum Biel

    Biel, 2501

  • Hôpital de La Tour

    Carouge, 1227

  • Cardiomed - Jura

    Courrendlin, 2830

  • Centre de Cardiologie

    Delémont, 2800

  • Schlossberg Ärztezentrum

    Frauenfeld, 8500

  • Hôpitaux Universitaires de Genève

    Geneva, 1205

  • Hôpitaux Universitaires de Genève

    Geneva, 1211

  • Spital Lachen AG

    Lachen, 8853

  • CHUV-Centre hospitalier universitaire vaudois

    Lausanne, 1011

  • Luzerner Kantonsspital

    Lucerne, 6004

  • Herzzentrum Hirslanden Zentralschweiz

    Lucerne, 6006

  • Hôpital de Morges

    Morges, 1110

  • Dr. med. Eleni Goulouti

    Neuchâtel, 2000

  • Kantonsspital Olten

    Olten, 4600

  • Herzpraxis Regensdorf

    Regensdorf, 8105

  • Herzpraxis Sankt Gallen

    Sankt Gallen, 9000

  • Kantonsspital Obwalden

    Sarnen, 6060

  • Rehaklinik Seewis

    Seewis, 7212

  • Dr. med. Kiril Tzvetanov

    Sierre, 3960

  • Herzpraxis Sursee

    Sursee, 6210

  • Kardiologie Aarezentrum Thun

    Thun, 3600

  • Spital STS AG

    Thun, 3600

  • Hôpital Fribourgeois

    Villars-sur-Glâne, 1752

  • Herz- und Physiozentrum

    Wallisellen, 8304

  • Arztpraxis Waltenschwil

    Waltenschwil, 5622

  • Spital Will

    Will, 9500

  • Herz- und Kreislaufpraxis Winterthur

    Winterthur, 8400

  • Medbase Winterthur Neuwiesen

    Winterthur, 8400

  • Hôpital d'Yverdon-les-Bains

    Yverdon-les-Bains, 1400

  • Spital Zollikerberg

    Zollikerberg, 8125

  • SICADE Clinic

    Zurich, 8001

  • Herzpraxis Enge ZH

    Zurich, 8002

  • Gruppenpraxis Dr. Deseö / Dr. Deseö-Schütz / Dr. Lorger

    Zurich, 8008

  • Herzklinik Hirslanden

    Zurich, 8032

  • HerzKlinik Zürich Hirslanden

    Zurich, 8032

  • Herzkreislaufpraxis

    Zurich, 8055

  • Universitätsspital Zürich

    Zurich, 8091

Other trials in Switzerland

Bulgaria35 sites

  • Dr. Mircheva

    Burgas, 8000

  • Dr. Yordanov

    Haskovo, 6304

  • MBAL Atanas Dafovski, Kardzhali

    Kardzhali, 6600

  • Dr. Krasteva

    Kyustendil, 2501

  • Dr. Todorov

    Lovech, 5500

  • Dr. Tsoneva

    Lovech, 5500

  • Dr. Pavlov

    Parvomay, 4270

  • Medical Center, Pazardjik

    Pazardzhik, 4400

  • Dr. Stankova

    Pernik, 2300

  • assoc.prof. Gospodinov

    Pleven, 5800

  • dr. Kostadinovska

    Pleven, 5800

  • prof.Tisheva

    Pleven, 5800

  • Dr. Mekenian

    Plovdiv, 4001

  • Dr. Ilchev

    Plovdiv, 4002

  • Dr. Hairabedian

    Plovdiv, 4018

  • Dr. Filipov

    Plovdiv, 4020

  • MBAL Sliven, Dr. Bletsova

    Sliven, 8800

  • Dr. Pancheva

    Sofia, 1000

  • prof. Velchev

    Sofia, 1000

  • dr. Georgieva

    Sofia, 1202

  • dr. Karchinova

    Sofia, 1202

  • prof.Vitlianova

    Sofia, 1202

  • dr. Petrusheva

    Sofia, 1233

  • dr. Garvanski

    Sofia, 1407

  • Dr. Naidenova

    Sofia, 1431

  • Dr. Varnaliiska

    Sofia, 1431

  • prof. Karamfiloff

    Sofia, 1431

  • Dr. Nossikov

    Sofia, 1784

  • Dr. Gospodinov

    Stara Zagora, 6004

  • Dr. Trendafilova

    Targovishte, 7700

  • dr. Belcheva

    Varna, 9000

  • dr. Mancheva

    Varna, 9003

  • dr. Gyuzelev

    Varna, 9010

  • Dr. Petrova

    Yambol, 8600

  • Dr. Toneva-Zhelaeva

    Yambol, 8600

Other trials in Bulgaria

Hungary13 sites

  • Állami Szívkórház

    Balatonfüred, 8230

  • Gottsegen György National Cardiovascular Center

    Budapest, 1096

  • Heart and Vascular Centre, Semmelweis University

    Budapest, 1122

  • Sante Cons Bt.

    Budapest, 1133

  • DE Klinikai Központ Kardiológia és Szívsebészet

    Debrecen, 4032

  • Dombóvári Szent Lukács Kórház

    Dombóvár, 7200

  • Lahynara Bt

    Dunavarsány, 2336

  • Kardiológia Magánrendelő

    Eger, 3300

  • Mohácsi Kórház

    Mohács, 7700

  • Coromed-Smo

    Pécs, 7623

  • University of Pécs

    Pécs, 7624

  • Soproni Erzsébet Oktató Kórház

    Sopron, 9400

  • Újszeged Egészségközpont

    Szeged, 6726

Other trials in Hungary

About this study

Official title: Empagliflozin Functional Capacity - Non-Interventional Study

This is a multinational non-interventional study based on newly collected data to assess demographics, disease, and treatment pattern of patients with chronic Heart Failure (HF) in a two-cohort design: one cohort will receive first prescription of empagliflozin as routine therapy for HF, the other cohort will receive HF therapy with drugs with another mechanism of action. Treatment of HF according to routine practice is determined by the physician independent of the participation of the patient in this non-interventional study.

Conditions
Heart Failure
Being tested
Empagliflozin
Medical subject headings
Heart Failure

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • EmpagliflozinDrug

    Also called Jardiance®

    Empagliflozin was administered according to the approved product information.

Study groups in NCT05350202
Study groupRoleWhat they receive
Empagliflozin-treated patientsPatients with heart failure (HF), with or without diabetes, who received their first prescription of empagliflozin were treated according to the approved product information, with a recommended daily dose of 10 milligrams (mg).
Receives: Drug: Empagliflozin
Non-SGLT2i-treated patientsPatients with heart failure (HF), with or without diabetes, who received drugs with mechanisms of action other than empagliflozin (drugs other than SGLT2i (Sodium-Glucose Co-Transporter 2 inhibitors)) were treated according to the approved product information.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Change of the Kansas City Cardiomyopathy Questionnaire (KCCQ) Scores in Patients Newly Treated With Empagliflozin According to Routine Practice

    Change from baseline to Week 24 of the Kansas City Cardiomyopathy Questionnaire (KCCQ) scores, calculated as [Week 24] - [Baseline]. The KCCQ includes 23 items across 7 domains: physical limitation, symptom stability, symptom frequency, symptom burden, self-efficacy, quality of life, and social limitation. This outcome measured the total symptom score (TTS), clinical summary score (CSS), and overall summary score (OSS) in the empagliflozin-treated patients as defined in the clinical study protocol. The TTS evaluates symptom frequency and burden and is calculated as the mean of the symptom frequency score and symptom burden score. The CSS is calculated as the mean of the physical limitation score and total symptom score. The OSS is calculated as the mean of the physical limitation score, total symptom score, quality of life score, and social limitation score. The TTS, CSS, and OSS are represented on a 0-to-100-point scale, where a higher score reflects better health status.

    Measured: At baseline and at week 24.

Secondary outcomes (4)

  1. Change of the New York Heart Association (NYHA) Class in Patients Newly Treated With Empagliflozin

    This outcome measured the number of patients newly treated with empagliflozin who experienced a change in the New York Heart Association (NYHA) Class from baseline to Week 24. The NYHA Classes of heart failure categorize patients with symptomatic or advanced heart failure based on their physical activity limitations. Class I patients present no limitation of physical activity, and ordinary physical activity does not cause fatigue, palpitations, or shortness of breath. Class II patients present a slight limitation of physical activity, characterized by fatigue, palpitations, shortness of breath, or chest pain as a result of ordinary physical activity. Class III patients are characterized by a marked limitation of physical activity, where less than ordinary activity causes fatigue, palpitations, shortness of breath, or chest pain. Class IV patients present symptoms of heart failure at rest, where any physical activity causes further discomfort.

    Measured: At baseline and at Week 24.

  2. Number of Participants With Comorbidities

    Number of patients with first prescription of empagliflozin and patients prescribed drugs other than SGLT2 inhibitors with concomitant disease/comorbidities. Concomitant diseases/comorbidities are presented according to the ICD-10-CM (the International Classification of Diseases, Tenth Revision, Clinical Modification) standardized system using the disease code.

    Measured: At baseline.

  3. Number of Participants With Concomitant Heart-failure (HF) Related Medication

    Number of patients who took concomitant HF-related medication.

    Measured: At baseline.

  4. Hospitalizations Due to Heart-failure in the Past 6 Months Before Baseline

    Number of patients hospitalized at least one time due to heart failure (HF).

    Measured: Up to 6 months prior to baseline visit.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted28 Apr 2022
  2. Study start18 Dec 2022
  3. Primary completion25 Jul 2024
  4. Study completion25 Jul 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
3,431 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT05350202
Sponsor's protocol ID
1245-0259
Status last verified
Aug 2025
First submitted
22 Apr 2022
Last updated
26 Aug 2025
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: Once the criteria in section "Time Frame" are fulfilled, researchers can use the following link https://www.mystudywindow.com/msw/datasharing to request access to the clinical study documents regarding this study, and upon a signed "Document Sharing Agreement". Furthermore, researchers can request access to the clinical study data, for this and other listed studies, after the submission of a research proposal and according to the terms outlined in the website.

Questions about this trial

What is this clinical trial studying?

An observational study of Heart Failure, run by Boehringer Ingelheim at 350 sites in 6 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 26 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 350 sites in Poland, Romania, Czechia, Switzerland, Bulgaria and 1 more country. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 26 Aug 2025). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change of the Kansas City Cardiomyopathy Questionnaire (KCCQ) Scores in Patients Newly Treated With Empagliflozin According to Routine Practice (time frame: At baseline and at week 24.). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT05350202.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Aug 2025.

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