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TelerehabilitationNCT05435885

Postoperative Telerehabilitation in Older Adults

A study testing Pulmonary Tele-Rehabilitation in people with Telerehabilitation and Carcinoma, Non-Small-Cell Lung, run by Pusan National University Hospital at 1 site in South Korea.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

The purpose of this study is to confirm the effectiveness of a mobile messenger-based home tele-rehabilitation protocol in patients who have undergone lung resection surgery. By analyzing the difference from the existing postoperative pulmonary rehabilitation, the investigators would like to propose a new pulmonary… Read more about this study

Who is it for?
Ages 65 years and older
What is being tested?
Pulmonary Tele-Rehabilitation
Could I receive a placebo?
No, everyone receives an active treatment
How many people
64 participants
Where
1 siteSouth Korea
Study dates
25 Jul 2022to 16 Feb 2024
Phase
Interventional

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 65 years and older
  • All sexes
  • No healthy volunteers
  • Older adult

Who may be able to join

  • A person who is suspected of lung cancer and is scheduled to undergo a thoracoscopic lung resection surgery.
  • men and women the age ≥65 years.
  • A person who understands the course of the clinical trial and signs the informed consent form.

Who cannot join

  • Patients whose activity is restricted due to other diseases (e.g. osteoarthritis, spinal disease, cerebral infarction, etc.)
  • Patients who cannot test bioimpedance analysis due to the insertion of artificial pacemakers and defibrillators
  • A person who has difficulty judging himself/herself due to dementia, etc
  • Those enrolled in other clinical trials
  • A person deemed inappropriate to participate in this clinical trial under the judgement of the investigator.
  • A person who cannot use mobile messenger

Trial locations and contacts

1 site in 1 country.

South Korea1 site
  • PusanNUH

    Pusan

Other trials in South Korea

About this study

Official title: Comparison of Postoperative Telerehabilitation and Unsupervised Home-Based Training in Older Adults With Lung Cancer: A Randomized Controlled Trial

The purpose of this study is to confirm the effectiveness of a mobile messenger-based home tele-rehabilitation protocol in patients who have undergone lung resection surgery.

By analyzing the difference from the existing postoperative pulmonary rehabilitation, the investigators would like to propose a new pulmonary tele-rehabilitation protocol.

Read the detailed description

This randomized controlled trial aims to evaluate the effectiveness of a mobile messenger-based home pulmonary telerehabilitation protocol in patients undergoing lung lobectomy. All participants receive standard perioperative rehabilitation and education. The intervention group receives additional customized exercise instructions and real-time support via KakaoTalk for 4 weeks, including aerobic, resistance, and breathing exercises. The control group receives one-time education without remote monitoring. Primary outcome is VO₂peak; secondary outcomes include respiratory function, muscle strength, body composition, quality of life, and exercise adherence.

Being tested
Pulmonary Tele-Rehabilitation, Control (Education)
Medical subject headings
Carcinoma, Non-Small-Cell Lung

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Pulmonary Tele-RehabilitationOther

    12 supervised training sessions via a specific mobile messenger during four weeks. (3 sessions/week)

  • Control (Education)Other

    Usual care with only one educational session.

Study groups in NCT05435885
Study groupRoleWhat they receive
Tele-rehabilitation groupExperimentalThe Tele-rehabilitation group performs 12 training sessions during four weeks. (3 sessions/week)
Receives: Other: Pulmonary Tele-Rehabilitation
Control groupOtherThe control group receives usual care with only one educational session.
Receives: Other: Control (Education)

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Change From Baseline in VO2 Peak (Peak Oxygen Uptake, mL/kg/Min) on the CardioPulmonary Exercise Test(CPET) After 4 Weeks Intervention

    Cardiopulmonary exercise test (CPET) also referred to as a VO2 (oxygen consumption) test, is a specialized type of stress test or exercise test that measures participants exercise ability.

    Measured: Before surgery (Pre), Baseline (4 weeks after surgery), After intervention(8 weeks after surgery), Follow up(12 weeks after surgery)

Secondary outcomes (11)
  1. Ventilatory Efficiency (VE/VCO₂ Slope)

    VE/VCO₂ slope measured during CPET. Lower values indicate better ventilatory efficiency.

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  2. Maximal Inspiratory Pressure (MIP)

    Maximal inspiratory pressure measured using a handheld respiratory device. Higher values indicate stronger inspiratory muscles. Unit of Measure: cmH₂O

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  3. Skeletal Muscle Index (SMI)

    Skeletal muscle index calculated by dividing appendicular skeletal muscle mass by height squared. Higher values indicate greater muscle mass.

    Unit of Measure: kg/m²

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  4. Hospital Anxiety and Depression Scale (HADS)

    The Hospital Anxiety and Depression Scale (HADS) was devised 30 years ago by Zigmond and Snaith to measure anxiety and depression in a general medical population of patients.

    The HADS is a fourteen item scale that generates: Seven of the items relate to anxiety and seven relate to depression.

    Each item on the questionnaire is scored from 0-3 and this means that a person can score between 0 and 21 for either anxiety or depression.

    0-7 = Normal 8-10 = Borderline abnormal (borderline case) 11-21 = Abnormal (case)

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  5. EQ-5D (EuroQol-5 Dimension)

    The EQ-5D-5L is a standardized instrument developed by the EuroQol Group to measure health-related quality of life. It consists of two parts: a descriptive system and a visual analogue scale (EQ VAS).

    The descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Each dimension has five levels:

    (1) no problems, (2) slight problems, (3) moderate problems, (4) severe problems, and (5) extreme problems.

    Responses are converted into a summary index score, which ranges from -0.281 to 1.000, based on country-specific value sets. Higher index scores indicate better health status, with 1.000 representing full health and values below 0 indicating health states considered worse than death.

    The EQ VAS records the participant's self-rated health on a vertical visual analogue scale ranging from 0 to 100, where 100 represents the best health imaginable and 0 represents the worst health imaginable.

    Higher VAS scores reflect

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  6. Grip Strength

    Grip strength is a measure of muscular strength or the maximum force/tension generated by participant's forearm muscles using the Jamar Hydraulic Hand Dynamometer.

    The force has been measured in kilograms.

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  7. Steps

    As a physical activity, Counting participant's steps per a day with an activity tracker.

    Average number of steps per day for one week before surgery and after discharge.

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  8. Peak Expiratory Flow (PEF)

    The peak expiratory flow (PEF) is a participant's maximum speed of expiration, as measured with a peak flow meter, a small, hand-held device used to monitor a participant's ability to breathe out air. It measures the airflow through the bronchi and thus the degree of obstruction in the airways. Peak expiratory flow is typically measured in units of liters per minute (L/min).

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  9. Forced Vital Capacity (FVC)

    Forced vital capacity (FVC) is the maximum amount of air a participant can forcibly exhale from lungs after fully inhaling.

    The unit is expressed in liters.

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  10. The Forced Expiratory Volume in 1 Second (FEV1)

    The forced expiratory volume in 1 second (FEV1) is the volume of air (in liters) exhaled in the first second during forced exhalation after maximal inspiration.

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

  11. Whole-Body Phase Angle

    Bioelectrical impedance analysis (BIA)-derived phase angle (PA) is an alternative method to assess mortality risk. BIA is a simple, non-invasive technique that estimates body composition by measuring the opposition (impedance) to an applied current while passing through the body. Impedance consists of two components: resistance, which is the opposition to the flow of an alternating current through intra- and extracellular ionic solutions, and reactance, which is the delay in conduction as a result of capacitance by cell membranes and tissue interfaces.

    PA is regarded as a biological marker of cellular health, as it reflects cell mass, membrane integrity, and hydration status. PA has repeatedly proven to be a predictor of morbidity and mortality in various patient groups.

    Measured: Immediately After Rehabilitation and at 4-Week Follow-Up

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted28 Jun 2022
  2. Study start25 Jul 2022
  3. Primary completion16 Feb 2024
  4. Study completion16 Feb 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
64 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT05435885
Sponsor's protocol ID
2205-033-114
Status last verified
Sep 2026
First submitted
23 Jun 2022
Last updated
8 Oct 2026
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Shin YB, Huh S, Cho JS, Hong CH, Kim Y, Shin MJ, Yun RY, Lee J, Son BS, Kim SH. Comparison of Postoperative Telerehabilitation and Unsupervised Home-Based Training in Older Adults With Lung Cancer: A Randomized Controlled Trial. J Cardiopulm Rehabil Prev. 2026 Mar 1;46(2):132-139. doi: 10.1097/HCR.0000000000000988. Epub 2025 Nov 26.

    PubMed 41294889

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