Low Back PainSCSCRLCSNCT05505851
Sequential Core Stability Corrective Exercise Approach in Lower Crossed Syndrome
A study testing Sequential Core Stability Corrective Exercise Approach in people with Low Back Pain, run by Riphah International University at 1 site in Pakistan.
Trial summary
The objective of the study will be to determine the effects of Sequential Core Stability Corrective Exercise Approach for Alignment and Muscle Function in Lower Crossed Syndrome. Read more about this study
- Who is it for?
- Ages 18 to 28 yearsHealthy volunteers can take part
- Conditions the study is for
- Low Back Pain
- What is being tested?
- Sequential Core Stability Corrective Exercise Approach
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 sitePakistan
- Study dates
- 10 Feb 2024to 1 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 28 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- • Age group between 18 to 28 years
- No current incidence of low back pain or past history of low back dysfunction
- Kendall double leg lowering test: Abdominal muscle weakness to the extent of not being able to maintain posterior pelvic tilt during a double leg lowering test in supine position.
- Diagnosed with lower cross syndrome through assessment criteria of Janda muscle testing and assessment
Who cannot join
- • Having any history of low back pain, spinal trauma,
- Joint dysfunction in past 3 months
- Congenital deformities at hip or lumbar region,
- Recent fracture to related joints in past 6 months
- Any family history of cardiopulmonary disease
- Any disease or urogenital tract
Show all 10Show fewer
- Participants having BMI above 30.
- Recent history of hepatitis or Fatty liver or
- Any athlete having high physical activity.
- History of abdominal, hip or lumbar surgeries in past 3 months
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Sequential Core Stability Corrective Exercise Approach for Alignment And Muscle Function In Lower Crossed Syndrome
The objective of the study will be to determine the effects of Sequential Core Stability Corrective Exercise Approach for Alignment and Muscle Function in Lower Crossed Syndrome.
Read the detailed description
Lower Crossed Syndrome is one of common postural disorder which occurs due to the muscular imbalance. It refers to specific altered muscle activation and movement patterns along with some postural deviations. Alterations in muscle activation include overactivity of hip flexors and lower back muscles paired underactivity of abdominals and gluteus muscle. This pattern of imbalance creates dysfunction. Postural correction exercise with inner and outer core muscles are necessary. There are different traditional structural approach, functional approach and biomechanics and are presumed to lead to adjustments in the length and strength of local muscles while ignoring other related malalignments and core stability. The objective of the study will be to determine the effects of Sequential Core Stability Corrective Exercise Approach for Alignment and Muscle Function in Lower Crossed Syndrome.
It will be a randomized controlled trial. Sample size will be collected after running the pilot study. The participants will be recruited through convenient sampling technique and then allocated randomly to Groups. Outcome measures will be alignment and muscle function. Pre and post reading and after one month follow-up will be recorded. Data will be analyzed using statistical package for social sciences software version 25. After assessing normality of data by Shapiro-Wilk test, it will be decided either parametric or nonparametric test will be use within a group or between two groups.
Keywords: Alignment, Core Stability, Diaphragm, Muscular Imbalance, Muscle thickness Pelvic floor.
- Conditions
- Low Back Pain
- Being tested
- Control, Sequential Core Stability Corrective Exercise Approach
- Keywords
- Alignment, Core Stability, Diaphragm, Pelvic floor, Dysfunction
- Medical subject headings
- Low Back Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ControlOther
Corrective Exercises: Hip Flexor Stretch, Thoracolumbar Extensor Stretch, Abdominal Curl, and Glute Bridge.
Sequential Core Stability Corrective Exercise ApproachOther
Sequential Core Stability Corrective Exercise Approach
- Corrective Exercises
- Diaphragm Training Program
- Pelvic floor Muscle training
- Core Stability exercises
- Beginning
- Progressing
- Advanced
| Study group | Role | What they receive |
|---|---|---|
| A: Control | Active comparator | Corrective Exercises:
Hip Flexor Stretch, Thoracolumbar Extensor Stretch, Abdominal Curl, and Glute Bridge. Receives: Other: Control |
| B: Sequential Core Stability Corrective Exercise Approach | Experimental | Sequential Core Stability Corrective Exercise Approach
1. Corrective Exercises
2. Diaphragm Training Program
3. Pelvic floor Muscle training
4. Core Stability exercises Receives: Other: Sequential Core Stability Corrective Exercise Approach |
What is being measured
The primary outcome is the main question the study is designed to answer.
Photometry for Pelvic Tilt
Angle of Pelvic tilt will be measured Through a Reliable and validated camera.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Photometry for Chest Expansion
Angle of Chest expansion will be measured at Nipple line, Xiphoid level and at waist level, Through a Reliable and validated camera.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Photometry for Cervicothoracic level
Angle of C7-T1 will be measured Through a Reliable and validated camera.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Photometry for Lumber flexion
Angle of Lumber curve will be measured Through a Reliable and validated camera.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Diaphragmatic excursion
To assess the diaphragmatic motion by M-mode US a 2.5-5 megahertz (MHz) phase array will be used.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Levator ani Excursion
To assess the pelvic floor motion by M-mode US a 2.5-5 megahertz (MHz) array will be used.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Diaphragmatic thickness and thickening
diaphragmatic thicknesses and thickening will be assessed by B-mode ultrasonography during various respiratory maneuvers
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Levator ani thickness and thickening
Levator ani thicknesses and thickening will be assessed by B-mode ultrasonography during various respiratory maneuvers
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Core stability
It will be measured by Pressure biofeedback unit for the transverse abdomens.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Secondary outcomes (3)
Forced Vital Capacity (FVC)
Pulmonary function test through spirometer, It will be measured by digital spirometer.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Forced Expiratory Volume per second FEV1
Pulmonary function test through spirometer, It will be measured by digital spirometer.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Ratio of FEV1/ FVC
Pulmonary function test through spirometer, It will be measured by digital spirometer.
Measured: Pre (0th week), Post (6th week), (12th week) Follow-up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Aug 2022
- Study start10 Feb 2024
- Primary completion1 Dec 2025
- Study completion1 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Low Back PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- 2
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Muhammad Kashif, PhD, Study chair, Riphah International UniversityWajeeha Zia, PhD*, Principal investigator, Riphah International University , QIE, Campus
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05505851
- Sponsor's protocol ID
- REC/RCR & AHS/22/1104
- Acronym
- SCSCRLCS
- Status last verified
- Dec 2025
- First submitted
- 23 May 2022
- Last updated
- 15 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Sequential Core Stability Corrective Exercise Approach for Alignment And Muscle Function In Lower Crossed Syndrome
- ClinicalTrials.gov ID
- NCT05505851
- Acronym / sponsor ID
- SCSCRLCS / REC/RCR & AHS/22/1104
- Conditions
- Low Back Pain
- Keywords
- Alignment, Core Stability, Diaphragm, Pelvic floor, Dysfunction
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 10 Feb 2024 (actual)
- Primary completion
- 1 Dec 2025 (actual)
- Study completion
- 1 Dec 2025 (actual)
- First posted
- 18 Aug 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective of the study will be to determine the effects of Sequential Core Stability Corrective Exercise Approach for Alignment and Muscle Function in Lower Crossed Syndrome.
Detailed description
Lower Crossed Syndrome is one of common postural disorder which occurs due to the muscular imbalance. It refers to specific altered muscle activation and movement patterns along with some postural deviations. Alterations in muscle activation include overactivity of hip flexors and lower back muscles paired underactivity of abdominals and gluteus muscle. This pattern of imbalance creates dysfunction. Postural correction exercise with inner and outer core muscles are necessary. There are different traditional structural approach, functional approach and biomechanics and are presumed to lead to adjustments in the length and strength of local muscles while ignoring other related malalignments and core stability. The objective of the study will be to determine the effects of Sequential Core Stability Corrective Exercise Approach for Alignment and Muscle Function in Lower Crossed Syndrome.
It will be a randomized controlled trial. Sample size will be collected after running the pilot study. The participants will be recruited through convenient sampling technique and then allocated randomly to Groups. Outcome measures will be alignment and muscle function. Pre and post reading and after one month follow-up will be recorded. Data will be analyzed using statistical package for social sciences software version 25. After assessing normality of data by Shapiro-Wilk test, it will be decided either parametric or nonparametric test will be use within a group or between two groups.
Keywords: Alignment, Core Stability, Diaphragm, Muscular Imbalance, Muscle thickness Pelvic floor.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- 2
| Arm | Type | Receives |
|---|---|---|
| A: Control | Active comparator | Other: ControlCorrective Exercises: Hip Flexor Stretch, Thoracolumbar Extensor Stretch, Abdominal Curl, and Glute Bridge. |
| B: Sequential Core Stability Corrective Exercise Approach | Experimental | Other: Sequential Core Stability Corrective Exercise ApproachSequential Core Stability Corrective Exercise Approach 1. Corrective Exercises 2. Diaphragm Training Program 3. Pelvic floor Muscle training 4. Core Stability exercises |
Who may qualify
- Ages
- 18 to 28 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- • Age group between 18 to 28 years
Key exclusion criteria (10 listed)
- • Having any history of low back pain, spinal trauma,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ControlCorrective Exercises: Hip Flexor Stretch, Thoracolumbar Extensor Stretch, Abdominal Curl, and Glute Bridge. | Other | A: Control |
| Sequential Core Stability Corrective Exercise ApproachSequential Core Stability Corrective Exercise Approach 1. Corrective Exercises 2. Diaphragm Training Program 3. Pelvic floor Muscle training 4. Core Stability exercises 1. Beginning 2. Progressing 3. Advanced | Other | B: Sequential Core Stability Corrective Exercise Approach |
Primary outcome
Photometry for Pelvic Tilt
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
Angle of Pelvic tilt will be measured Through a Reliable and validated camera.
Photometry for Chest Expansion
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
Angle of Chest expansion will be measured at Nipple line, Xiphoid level and at waist level, Through a Reliable and validated camera.
Photometry for Cervicothoracic level
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
Angle of C7-T1 will be measured Through a Reliable and validated camera.
Photometry for Lumber flexion
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
Angle of Lumber curve will be measured Through a Reliable and validated camera.
Diaphragmatic excursion
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
To assess the diaphragmatic motion by M-mode US a 2.5-5 megahertz (MHz) phase array will be used.
Levator ani Excursion
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
To assess the pelvic floor motion by M-mode US a 2.5-5 megahertz (MHz) array will be used.
Diaphragmatic thickness and thickening
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
diaphragmatic thicknesses and thickening will be assessed by B-mode ultrasonography during various respiratory maneuvers
Levator ani thickness and thickening
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
Levator ani thicknesses and thickening will be assessed by B-mode ultrasonography during various respiratory maneuvers
Core stability
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
It will be measured by Pressure biofeedback unit for the transverse abdomens.
3 secondary outcomes
Forced Vital Capacity (FVC)
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
Forced Expiratory Volume per second FEV1
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
Ratio of FEV1/ FVC
Time frame: Pre (0th week), Post (6th week), (12th week) Follow-up
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Dec 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Muhammad Kashif, PhD study chair
Riphah International University
Wajeeha Zia, PhD* principal investigator
Riphah International University , QIE, Campus
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Sequential Core Stability Corrective Exercise Approach in people with Low Back Pain, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Photometry for Pelvic Tilt (time frame: Pre (0th week), Post (6th week), (12th week) Follow-up). The study lists 9 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Dec 2025.