SuicideMSVCACNCT05514587
Meaning of Life Questionnaire (MLQ) in Patients Admitted to the Crisis Centre (MSVCAC)
An observational study of Suicide and Mental Suffering, run by Centre Hospitalier Régional Metz-Thionville at 2 sites in France.
Trial summary
Suicide is the highest mortality risk in psychiatry and about the only life-threatening risk associated with the evolution of mental illness. Worldwide, more than 800,000 people die by suicide each year. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Suicide, Mental Suffering, Meaning of Life
- What is being tested?
- Meaning of Life Questionnaire (MLQ)
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 119 participants
- Where
- 2 sitesFrance
- Study dates
- 29 Sep 2022to 15 Sep 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Adult, Older adult
Study population: Three groups of people are served at the Crisis Centre: 1. Those who have committed a suicidal act, 2. Having suicidal thoughts without acting on them, 3. Without suicidal ideation or acting out of crisis patients admitted to the Crisis Center.
Who may be able to join
- Patients admitted to the Crisis Centre of the CHR Bel Air Hospital or the CAC Jury
- Male or female, at least 18 years old
- Hospitalized at the CAC-SPUL Bel Air or CAC de Jury
- Patient not objecting to participate in the study
Who cannot join
- Refused to take part in the study
- Not being able to answer the questionnaire (lack of language skills, cognitive problems related to their pathology, etc.).
Trial locations and contacts
2 sites in 1 country.
France2 sites
Centre Hospitalier Jury
Metz, 57073
CHR Metz-Thionville/Hopital de Mercy
Metz, 57085
About this study
Official title: Validation of the French Translation of the Meaning of Life Questionnaire (MLQ) in Patients Admitted to the Crisis Centre
Suicide is the highest mortality risk in psychiatry and about the only life-threatening risk associated with the evolution of mental illness. Worldwide, more than 800,000 people die by suicide each year. Although the number of deaths by suicide has decreased in France (from 11,000 in the 1990s to 9,000 today), suicide is still a major public health problem (the French rate is one of the highest in Europe).
The World Health Organisation (WHO) has declared a state of emergency and is pushing each country to develop a global multisectoral strategy for effective suicide prevention. To this end, suicide risk assessment tools have been developed for predictive purposes. However, diagnosis remains difficult and the risk of recidivism remains the fear of the psychiatrist. Questioning the subjects about their vision of their existence and the meaning they give to their life would perhaps help to better understand the psychology of the suicidal person. In recent decades, there has been research on meaning and suicide, and more recently a few studies have attempted to quantitatively investigate meaning as a protective factor. More recently, the COVID epidemic has brought the issue of meaning and suicide prevention to the forefront.
Read the detailed description
Suicide is the highest mortality risk in psychiatry and about the only life-threatening risk associated with the evolution of mental illness. Worldwide, more than 800,000 people die by suicide each year. In France, the latest estimates put the number of deaths by suicide at 9,000 per year, with 200,000 attempted suicides treated in emergency departments, leading to between 90,000 and 100,000 hospitalisations. Although the number of deaths by suicide has fallen in France (from 11,000 in the 1990s to 9,000 at present), suicide is still a major public health problem (the French rate remains one of the highest in Europe).
It is estimated that almost half of all suicides consult a general practitioner in the month before they commit suicide. Suicide affects young people as much as adults. It has become a major public health problem among adolescents. This dramatic act is often misunderstood, but almost always reflects psychological suffering, exhaustion and resignation. The World Health Organisation (WHO) has declared a state of emergency and is urging each country to develop a comprehensive multisectoral strategy for effective suicide prevention. To this end, suicide risk assessment tools have been developed with a predictive aim. Vigilance and surveillance systems such as "VigilanS " for suicidal people, structures such as crisis centres, and enhanced community support have been put in place. However, diagnosis remains difficult and the risk of recidivism remains the fear of the psychiatrist.
Suicide is about death, about putting an end to one's suffering by aspiring to a definitive appeasement of tensions. It is also a question of existential claim and it is at this level that the question of the meaning of life arises. Indeed, clinical practice very often confronts the psychiatrist, with suicidal subjects, with statements of the type (even if it is not formulated as clearly as the following sentence): "I want to die so as not to suffer any more and I claim the right to put an end to an existence that no longer has any meaning, I choose to finally find peace". How then can we understand that a person gives himself death because he no longer finds a reason to exist? And conversely, that having a reason to live gives a purpose to our existence and can help prevent suicide? It is in this sense that a hypothesis has been put forward over the last few decades, based on the principle that questioning subjects about the vision they have of their existence and the meaning they give to their lives would perhaps help to better understand the psychology of the suicidal person and to prevent them from committing suicide. This reflection, which has its roots in philosophy, has now led to empirical research that has endeavoured to study and take into account, but this time in a quantitative manner and no longer confining itself to philosophical reflection, the question of meaning as a protective factor against suicide: we shall return to this later in the course of this work. Finally, it should be noted that the COVID epidemic has brought the question of meaning and suicide prevention to the forefront, as evidenced by the deleterious impact of the COVID epidemic on adolescents.
- Conditions
- Suicide, Mental Suffering, Meaning of Life, Questionnaire
- Being tested
- Meaning of Life Questionnaire (MLQ)
- Medical subject headings
- Suicide
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Meaning of Life Questionnaire (MLQ)Behavioural
Also called Beck's Hopelessness Scale (BHS), Beck Suicidal Intent Scale (BSI), Beck Depression Inventory Short Form (BDI-SF), Satisfaction with Life Scale (SWLS)
Completion of questionnaires at crisis centre entry and 3 months later.
| Study group | Role | What they receive |
|---|---|---|
| Suicidal act | Patients who has committed a suicidal act Receives: Behavioral: Meaning of Life Questionnaire (MLQ) | |
| Suicidal thoughts without acting on them | Patients with suicidal thoughts without acting on them Receives: Behavioral: Meaning of Life Questionnaire (MLQ) | |
| No suicidal ideation or acting out | Patients without suicidal ideation or acting out of patients in crisis admitted to the Crisis Center Receives: Behavioral: Meaning of Life Questionnaire (MLQ) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Psychometric validation of the French translation of Steger's Meaning in Life Questionnaire (MLQ) in adult patients admitted to the Crisis Centre (CAC)
The Meaning of Life Questionnaire (MLQ) measures the presence of meaning in life, that is the subjective sense that one's life is meaningful, and the search for meaning in life, reflecting one's drive and orientation toward finding such meaning.
Measured: 3 months
Secondary outcomes (4)
Convergent validity of MLQ with Beck's hopelessness scale (BHS) in adult patients admitted to the Crisis Centre (CAC)
Beck's hopelessness scale (BHS) : 20 items, self-report scale, assesses current mental state with regard to thoughts about the future, motivation and expectations.
Measured: 3 months
Convergent validity of MLQ with Beck Suicide Intent Scale (BSI) in adult patients admitted to the Crisis Centre (CAC)
Beck Suicide Intent Scale (BSI): 20 items, assesses suicidal intent of the most recent episode of self-harm
Measured: 3 months
Convergent validity of MLQ with Satisfaction with Life Scale (SWLS) in adult patients admitted to the Crisis Centre (CAC)
The Satisfaction with Life Scale (SWLS) is a short 5-item instrument designed to measure global cognitive judgments of satisfaction with one's life. The scale usually requires only about one minute of a respondent's time.
Measured: 3 months
Convergent validity of MLQ with Satisfaction with Beck Depression Inventory Short Form (BDI-SF) in adult patients admitted to the Crisis Centre (CAC)
The Beck Depression Inventory Short Form (BDI-SF, BDI-13) consists of 13 items assessing the severity of depression symptoms.
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Aug 2022
- Study start29 Sep 2022
- Primary completion15 Jun 2023
- Study completion15 Sep 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for SuicideStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 119 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Régional Metz-Thionville
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Pascal MD LE VAOU, Principal investigator, CHR Metz Thionville Hopital de Mercy
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05514587
- Sponsor's protocol ID
- 2022-01Obs-CHRMT
- Acronym
- MSVCAC
- Status last verified
- Nov 2023
- First submitted
- 19 Aug 2022
- Last updated
- 7 Nov 2023
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Nov 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Validation of the French Translation of the Meaning of Life Questionnaire (MLQ) in Patients Admitted to the Crisis Centre
- ClinicalTrials.gov ID
- NCT05514587
- Acronym / sponsor ID
- MSVCAC / 2022-01Obs-CHRMT
- Conditions
- Suicide, Mental Suffering, Meaning of Life, Questionnaire
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 119 participants (actual)
- Lead sponsor
- Centre Hospitalier Régional Metz-ThionvilleUniversity, hospital or other
- Study start
- 29 Sep 2022 (actual)
- Primary completion
- 15 Jun 2023 (actual)
- Study completion
- 15 Sep 2023 (actual)
- First posted
- 24 Aug 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Suicide is the highest mortality risk in psychiatry and about the only life-threatening risk associated with the evolution of mental illness. Worldwide, more than 800,000 people die by suicide each year. Although the number of deaths by suicide has decreased in France (from 11,000 in the 1990s to 9,000 today), suicide is still a major public health problem (the French rate is one of the highest in Europe).
The World Health Organisation (WHO) has declared a state of emergency and is pushing each country to develop a global multisectoral strategy for effective suicide prevention. To this end, suicide risk assessment tools have been developed for predictive purposes. However, diagnosis remains difficult and the risk of recidivism remains the fear of the psychiatrist. Questioning the subjects about their vision of their existence and the meaning they give to their life would perhaps help to better understand the psychology of the suicidal person. In recent decades, there has been research on meaning and suicide, and more recently a few studies have attempted to quantitatively investigate meaning as a protective factor. More recently, the COVID epidemic has brought the issue of meaning and suicide prevention to the forefront.
Detailed description
Suicide is the highest mortality risk in psychiatry and about the only life-threatening risk associated with the evolution of mental illness. Worldwide, more than 800,000 people die by suicide each year. In France, the latest estimates put the number of deaths by suicide at 9,000 per year, with 200,000 attempted suicides treated in emergency departments, leading to between 90,000 and 100,000 hospitalisations. Although the number of deaths by suicide has fallen in France (from 11,000 in the 1990s to 9,000 at present), suicide is still a major public health problem (the French rate remains one of the highest in Europe).
It is estimated that almost half of all suicides consult a general practitioner in the month before they commit suicide. Suicide affects young people as much as adults. It has become a major public health problem among adolescents. This dramatic act is often misunderstood, but almost always reflects psychological suffering, exhaustion and resignation. The World Health Organisation (WHO) has declared a state of emergency and is urging each country to develop a comprehensive multisectoral strategy for effective suicide prevention. To this end, suicide risk assessment tools have been developed with a predictive aim. Vigilance and surveillance systems such as "VigilanS " for suicidal people, structures such as crisis centres, and enhanced community support have been put in place. However, diagnosis remains difficult and the risk of recidivism remains the fear of the psychiatrist.
Suicide is about death, about putting an end to one's suffering by aspiring to a definitive appeasement of tensions. It is also a question of existential claim and it is at this level that the question of the meaning of life arises. Indeed, clinical practice very often confronts the psychiatrist, with suicidal subjects, with statements of the type (even if it is not formulated as clearly as the following sentence): "I want to die so as not to suffer any more and I claim the right to put an end to an existence that no longer has any meaning, I choose to finally find peace". How then can we understand that a person gives himself death because he no longer finds a reason to exist? And conversely, that having a reason to live gives a purpose to our existence and can help prevent suicide? It is in this sense that a hypothesis has been put forward over the last few decades, based on the principle that questioning subjects about the vision they have of their existence and the meaning they give to their lives would perhaps help to better understand the psychology of the suicidal person and to prevent them from committing suicide. This reflection, which has its roots in philosophy, has now led to empirical research that has endeavoured to study and take into account, but this time in a quantitative manner and no longer confining itself to philosophical reflection, the question of meaning as a protective factor against suicide: we shall return to this later in the course of this work. Finally, it should be noted that the COVID epidemic has brought the question of meaning and suicide prevention to the forefront, as evidenced by the deleterious impact of the COVID epidemic on adolescents.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Suicidal act | – | Behavioral: Meaning of Life Questionnaire (MLQ)Patients who has committed a suicidal act |
| Suicidal thoughts without acting on them | – | Behavioral: Meaning of Life Questionnaire (MLQ)Patients with suicidal thoughts without acting on them |
| No suicidal ideation or acting out | – | Behavioral: Meaning of Life Questionnaire (MLQ)Patients without suicidal ideation or acting out of patients in crisis admitted to the Crisis Center |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- Three groups of people are served at the Crisis Centre: 1. Those who have committed a suicidal act, 2. Having suicidal thoughts without acting on them, 3. Without suicidal ideation or acting out of crisis patients admitted to the Crisis Center.
Key inclusion criteria (4 listed)
- Patients admitted to the Crisis Centre of the CHR Bel Air Hospital or the CAC Jury
- Male or female, at least 18 years old
- Hospitalized at the CAC-SPUL Bel Air or CAC de Jury
- Patient not objecting to participate in the study
Key exclusion criteria (2 listed)
- Refused to take part in the study
- Not being able to answer the questionnaire (lack of language skills, cognitive problems related to their pathology, etc.).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Meaning of Life Questionnaire (MLQ)Also: Beck's Hopelessness Scale (BHS), Beck Suicidal Intent Scale (BSI), Beck Depression Inventory Short Form (BDI-SF), Satisfaction with Life Scale (SWLS)Completion of questionnaires at crisis centre entry and 3 months later. | Behavioural | No suicidal ideation or acting out, Suicidal act, Suicidal thoughts without acting on them |
Primary outcome
Psychometric validation of the French translation of Steger's Meaning in Life Questionnaire (MLQ) in adult patients admitted to the Crisis Centre (CAC)
Time frame: 3 months
The Meaning of Life Questionnaire (MLQ) measures the presence of meaning in life, that is the subjective sense that one's life is meaningful, and the search for meaning in life, reflecting one's drive and orientation toward finding such meaning.
4 secondary outcomes
Convergent validity of MLQ with Beck's hopelessness scale (BHS) in adult patients admitted to the Crisis Centre (CAC)
Time frame: 3 months
Convergent validity of MLQ with Beck Suicide Intent Scale (BSI) in adult patients admitted to the Crisis Centre (CAC)
Time frame: 3 months
Convergent validity of MLQ with Satisfaction with Life Scale (SWLS) in adult patients admitted to the Crisis Centre (CAC)
Time frame: 3 months
Convergent validity of MLQ with Satisfaction with Beck Depression Inventory Short Form (BDI-SF) in adult patients admitted to the Crisis Centre (CAC)
Time frame: 3 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Nov 2023.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Pascal MD LE VAOU principal investigator
CHR Metz Thionville Hopital de Mercy
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Suicide and Mental Suffering, run by Centre Hospitalier Régional Metz-Thionville at 2 sites in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 Nov 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Psychometric validation of the French translation of Steger's Meaning in Life Questionnaire (MLQ) in adult patients admitted to the Crisis Centre (CAC) (time frame: 3 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Nov 2023.