Vision DisordersNCT05600140
Viewing Strategy Training in Children With (Cerebral) Visual Impairment
A study testing Viewing strategy training in people with Vision Disorders and Vision, Low, run by Royal Dutch Visio at 1 site in Netherlands.
Trial summary
Viewing strategies are strategies used to process visual Information. Many children with visual impairment seem to lack systematic viewing strategies. However, it is unknown how viewing strategies differ between children with normal vision and children with (cerebral) visual impairment. Read more about this study
- Who is it for?
- Ages 5 to 12 yearsHealthy volunteers can take part
- Conditions the study is for
- Vision Disorders, Vision, Low
- What is being tested?
- Viewing strategy training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteNetherlands
- Study dates
- 25 Oct 2024to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 5 to 12 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
None listed.
Who cannot join
- Children with VI: linear near visual acuity >1.0 logMAR
- Children with visual field defect < 30 degrees
- Children with a verbal IQ below 70
- Children who attended a form of vision training in the past two years
- Children with psychiatric problems like ASS or AD(H)D
- Auditory impairment or language impairments
- Major life events during training
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Netherlands1 site, 1 recruiting
- Recruiting
Royal Dutch Visio
Nijmegen
Hanna Romema, MSc
hannarozema@visio.org
About this study
Official title: Viewing Strategy Training in Children With (Cerebral) Visual Impairment: From Spontaneous Eye Movements to a Structured Viewing Strategy
Viewing strategies are strategies used to process visual Information. Many children with visual impairment seem to lack systematic viewing strategies. However, it is unknown how viewing strategies differ between children with normal vision and children with (cerebral) visual impairment. In addition, viewing strategy training is often adopted in clinical practice, but till date there is no scientific evidence about effectiveness of this approach.
The current project has two goals: (1) to measure viewing strategies used by children with normal vision, children with ocular visual impairment and children with CVI, and (2) to evaluate whether training viewing strategies results in more efficiënt visual Information processing.
- Conditions
- Vision Disorders, Vision, Low
- Being tested
- Viewing strategy training
- Keywords
- viewing strategies, (cerebral) visual impairment, visual rehabilitation, reading strategies, visual search strategies
- Medical subject headings
- Vision Disorders, Vision, Low, Blindness, Cortical
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Viewing strategy trainingBehavioural
Children receive a visual training of viewing strategies (six weeks, 2 times a week, 30 minutes). During the training, children are instructed to use specific viewing strategies (looking in a structured direction which fits the task at hand, zooming in and out / change of visual selective attentional field, visual discrimination). The verbal instructions and exercises are protocol-based. A textbook is used to describe the reactions of the children during training.
| Study group | Role | What they receive |
|---|---|---|
| Group A) early training group | Experimental | T0 = baseline measurement T1 = posttest (within two weeks after training) T2 = follow up measurement (6 months after training) Receives: Behavioral: Viewing strategy training |
| Group B) late training group | Experimental | T0 = baseline measurement T1 = test-retest reliability and natural development (over period 1 1/2-2 months after T0) T2 = posttest (within two weeks after training) Receives: Behavioral: Viewing strategy training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Changes in reading accuracy after viewing strategy training
Radner reading test
Measured: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4
Changes in reading speed after viewing strategy training
Radner reading test
Measured: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4
Changes in visual search accuracy after training
Accuracy during conjunction search
Measured: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4
Changes in visual search speed after training
Speed during conjunction search
Measured: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in saccade amplitudes during reading and visual search after training
Saccade amplitudes measured using Radner reading test and conjunction search
Measured: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in fixation duration during reading and search after training
Fixation durations measured using Radner reading test and conjunction search
Measured: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in average distance between fixation points during conjunction search (EB-VSA) after training
Average distance between fixation points using Radner reading test and conjunction search
Measured: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Secondary outcomes (4)
Changes in WISC-V visual processing speed index (VSI) after training
WISC-IV visual processing speed index
Measured: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in local visual selective attention after training
TEA-Ch Speurtocht (total number of symbols found in 1 minute)
Measured: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in global visual selective attention after training
Gestalt Closure (Kaufman-ABC), number of correct answers
Measured: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in visual identification speed after training
'DST-Plaatjes Benoemen', number of pictures correctly named within 1 minute
Measured: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Oct 2022
- Study start25 Oct 2024
- Primary completionDec 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Vision DisordersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- For the first phase of the study, we aim to include 48 children aged 5-12 years for each group (i.e. normal Vision, ocular visual impairment, cerebral visual impairment). For the second phase of the study 60 children with visual impairment aged 5-9 years will be included (ocular impairment: n=30, cerebral visual impairment: n=30). In the second phase of the project, children receive a visual training of viewing strategies (six weeks, 2 times a week, 30 minutes). During the training, children are instructed to use specific viewing strategies (looking in a structured direction which fits the task at hand, zooming in and out / change of visual selective attentional field, visual discrimination). The verbal instructions and exercises are protocol based. A textbook is used to describe the reactions of the children during training.
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Royal Dutch Visio
- Sponsor type
- University, hospital or other
- Collaborators
- Radboud University, Behavioural Science Institute, Nijmegen, The Netherlands
- Responsible party
- Sponsor
- Investigators
- Bianca Huurneman, PhD, Principal investigator, Royal Dutch Visio
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05600140
- Sponsor's protocol ID
- NL81584.091.22
- Status last verified
- Jan 2026
- First submitted
- 12 Jul 2022
- Last updated
- 7 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Viewing Strategy Training in Children With (Cerebral) Visual Impairment: From Spontaneous Eye Movements to a Structured Viewing Strategy
- ClinicalTrials.gov ID
- NCT05600140
- Acronym / sponsor ID
- NL81584.091.22
- Conditions
- Vision Disorders, Vision, Low
- Keywords
- viewing strategies, (cerebral) visual impairment, visual rehabilitation, reading strategies, visual search strategies
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Royal Dutch VisioUniversity, hospital or other
- Collaborators
- Radboud University, Behavioural Science Institute, Nijmegen, The Netherlands
- Study start
- 25 Oct 2024 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 31 Oct 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Viewing strategies are strategies used to process visual Information. Many children with visual impairment seem to lack systematic viewing strategies. However, it is unknown how viewing strategies differ between children with normal vision and children with (cerebral) visual impairment. In addition, viewing strategy training is often adopted in clinical practice, but till date there is no scientific evidence about effectiveness of this approach.
The current project has two goals: (1) to measure viewing strategies used by children with normal vision, children with ocular visual impairment and children with CVI, and (2) to evaluate whether training viewing strategies results in more efficiënt visual Information processing.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- For the first phase of the study, we aim to include 48 children aged 5-12 years for each group (i.e. normal Vision, ocular visual impairment, cerebral visual impairment). For the second phase of the study 60 children with visual impairment aged 5-9 years will be included (ocular impairment: n=30, cerebral visual impairment: n=30). In the second phase of the project, children receive a visual training of viewing strategies (six weeks, 2 times a week, 30 minutes). During the training, children are instructed to use specific viewing strategies (looking in a structured direction which fits the task at hand, zooming in and out / change of visual selective attentional field, visual discrimination). The verbal instructions and exercises are protocol based. A textbook is used to describe the reactions of the children during training.
| Arm | Type | Receives |
|---|---|---|
| Group A) early training group | Experimental | Behavioral: Viewing strategy trainingT0 = baseline measurement T1 = posttest (within two weeks after training) T2 = follow up measurement (6 months after training) |
| Group B) late training group | Experimental | Behavioral: Viewing strategy trainingT0 = baseline measurement T1 = test-retest reliability and natural development (over period 1 1/2-2 months after T0) T2 = posttest (within two weeks after training) |
Who may qualify
- Ages
- 5 to 12 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (0 listed)
Key exclusion criteria (7 listed)
- Children with VI: linear near visual acuity >1.0 logMAR
- Children with visual field defect < 30 degrees
- Children with a verbal IQ below 70
- Children who attended a form of vision training in the past two years
- Children with psychiatric problems like ASS or AD(H)D
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Viewing strategy trainingChildren receive a visual training of viewing strategies (six weeks, 2 times a week, 30 minutes). During the training, children are instructed to use specific viewing strategies (looking in a structured direction which fits the task at hand, zooming in and out / change of visual selective attentional field, visual discrimination). The verbal instructions and exercises are protocol-based. A textbook is used to describe the reactions of the children during training. | Behavioural | Group A) early training group, Group B) late training group |
Primary outcome
Changes in reading accuracy after viewing strategy training
Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4
Radner reading test
Changes in reading speed after viewing strategy training
Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4
Radner reading test
Changes in visual search accuracy after training
Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4
Accuracy during conjunction search
Changes in visual search speed after training
Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Speed during conjunction search
Changes in saccade amplitudes during reading and visual search after training
Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Saccade amplitudes measured using Radner reading test and conjunction search
Changes in fixation duration during reading and search after training
Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Fixation durations measured using Radner reading test and conjunction search
Changes in average distance between fixation points during conjunction search (EB-VSA) after training
Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Average distance between fixation points using Radner reading test and conjunction search
4 secondary outcomes
Changes in WISC-V visual processing speed index (VSI) after training
Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in local visual selective attention after training
Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in global visual selective attention after training
Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Changes in visual identification speed after training
Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Bianca Huurneman, PhD principal investigator
Royal Dutch Visio
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Viewing strategy training in people with Vision Disorders and Vision, Low, run by Royal Dutch Visio at 1 site in Netherlands.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Bianca Huurneman, PhD (0(031)646944002, biancahuurneman@visio.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Changes in reading accuracy after viewing strategy training (time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jan 2026.