Clinical trials: Vision, Low
Low Vision, Retinitis Pigmentosa
Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision
Purpose: To validate a newly developed battery of performance-based tests of visual function to be presented using virtual reality.
- Conditions
- Low Vision, Retinitis Pigmentosa, Stargardt Disease 1, Stargardt Disease 3
- Trial name
- NCT04281732
- Testing
- Virtual Reality Headset based tests
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Queen's University, Belfast
Low Vision Aids
Assessing the Impact of eSight Go At-Home Usage in Individuals With Visual Impairment
This research aims to test the updated version of Gentex's device, eSight Go, an image enhancing wearable device to assist those with vision impairments limiting activities of daily living.
- Trial name
- eSight (NCT07149259)
- Testing
- At Home Use
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brooks Rehabilitation
Low Vision, Low Vision Aids
Beacon Sensors and Telerehabilitation to Assess and Improve Use of Devices (BeST-AID) for Low Vision
One goal of this research is to conduct a non-inferiority trial of telerehabilitation versus in-office care to provide follow-up training to individuals with low vision to enhance their quality of life by using magnification…
- Trial name
- BeST-AID (NCT06107881)
- Testing
- Low Vision Rehabilitation
- Where
- 9 sites in United States
- Volunteers
- 350 people
- Sponsor
- University of California, Los Angeles
Low Vision
Wearable Echolocation Aids Using Parametric Sound
The objective of this study is to study a novel device designed to aid patients with impaired vision to safely navigate their environment.
- Trial name
- NCT07218991
- Testing
- Wearable Echolocation Device
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Low Vision, Both Eyes
Virtual Reality-Base Intelligent Orientation and Mobility Specialists Trial
The human subject research is a randomized, controlled training trial that tests the effectiveness of three Virtual Reality-based Intelligent Orientation and Mobility Specialists (VR-IOMSs) in teaching orientation and mobility…
- Trial name
- VR-IOMS (NCT04639531)
- Testing
- Orientation and Mobility Training with VR-IOMSs, Orientation and Mobility Training with COMS, No Orientation and Mobility Training
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- University of Alabama at Birmingham
Visual Impairments, Low Vision Digital Assistance
Effectiveness of a Multi-disciplinary Vision Rehabilitation Programme in Improving the Overall Quality of Life of Visually Impaired Adults
This trial compares multidisciplinary vision rehabilitation and vision rehabilitation services to determine which service works better at improving overall quality of life for adults with visual impairment.
- Conditions
- Visual Impairments, Low Vision Digital Assistance, Adults
- Trial name
- NCT07827040
- Testing
- Multidisciplinary vision rehabilitaion, Vision rehabilitation incorporating low vision training only
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- The Hong Kong Polytechnic University
Low Vision in Children
Research and Development of Reading Visual Aids for Low-Vision Individuals Based on Virtual Reality Technology
Low vision substantially impairs reading ability and educational participation in adolescents. Existing assistive technologies, including optical magnifiers and electronic visual aids, are often limited by fragmented system…
- Trial name
- NCT07703449
- Testing
- VR-Based Intelligent Reading Aid, Natural Vision Reading (No Assistive Device)
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Age-related Macular Degeneration
Visual Remapping to Aid Reading With Field Loss
Reading performance in patients with Central Vision Loss and age matched controls with artificial scotomas will be measured with and without different kinds of remapping of missing text to different parts of the visual field.
- Trial name
- NCT03848663
- Testing
- Traditional Remapping, Personalized Remapping
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Retinitis Pigmentosa (RP), Rod Cone Dystrophy
Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment
This pilot clinical trial evaluates whether non-invasive brain stimulation improves the orientation and mobility (O\&M) skills of individuals with constricted visual fields in both eyes. The study is composed of three visits.
- Conditions
- Retinitis Pigmentosa (RP), Rod Cone Dystrophy, Visually Impaired Persons, Peripheral Visual Field Defect of Both Eyes
- Trial name
- NCT07341763
- Testing
- Active hf-tRNS.
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Waterloo
Retinal Disease, Age-Related Macular Degeneration
Stem Cell Ophthalmology Treatment Study II
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.
- Conditions
- Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease
- Trial name
- SCOTS2 (NCT03011541)
- Testing
- Arm 1
- Where
- 4 sites in United States, Austria and 1 more
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Arteritis, Giant Cell, Blindness and Low Vision
Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBO
Giant cell arteritis , also named Horton's disease, is the most common vasculitis in subjects over 50 years old. The incidence increases with age : from 188 to 290 cases per million inhabitants per year, with a North-South…
- Trial name
- CECIBO (NCT03841734)
- Testing
- treatment
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Low Vision, Central Visual Impairment
Vision Rehabilitation Training With Multimodal Feedback in Central Vision Loss
Central vision loss from macular degeneration creates blind spots that impair reading, face recognition, and navigation. Individuals must learn to use peripheral vision, requiring retraining of eye movements.
- Conditions
- Low Vision, Central Visual Impairment, Macular Degeneration
- Trial name
- NCT07577219
- Testing
- eccentric viewing training with biofeedback
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- New England College of Optometry
Vision, Low, Mobility Limitation
Evaluating Stairway Designs for Individuals With Vision Impairment
The goal of this study is to learn if contrast frequency on step tread-edges influences foot clearance measures, a marker of fall risk, in older adults with and without visual impairments.
- Trial name
- NCT07337317
- Testing
- Frequency of contrast marking on stair steps
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Alabama in Huntsville
Vestibular Hypofunction, Binocular Vision Abnormalities
Visual Influences on Vestibular Adaptation
The goal of this study is to learn whether a balance-training exercise called incremental vestibulo-ocular reflex adaptation (IVA) is safe and effective for adults with vision impairments, with or without additional vestibular…
- Conditions
- Vestibular Hypofunction, Binocular Vision Abnormalities, Reduced Vision
- Trial name
- NCT07380256
- Testing
- StableEyes: Incremental Vestibulo-Ocular Reflex Adaptation (IVA)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Low Vision, One Eye, Unspecified Eye, Low Vision Blindness
Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers
Investigators aim to assess the feasibility of delivering two augmentation interventions, Meditation and a Health Enhancement Program, for potentially enhancing the quality of life and mental health of Irreversible Age-Related…
- Trial name
- NCT03166072
- Testing
- Meditation, Health Enhancement Program
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Low Vision Aids
Shilangqing Smart Reading Aid for Improving Reading Ability in Children With Low Vision
This clinical trial aims to assess the efficacy and safety of the Shilangqing Smart Reading Aid, a head-mounted device integrating XR and AI technologies, in improving reading performance and quality of life among children with…
- Trial name
- NCT07336069
- Testing
- "Langshiqng" visual aid device
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Vision Disorders, Vision, Low
Viewing Strategy Training in Children With (Cerebral) Visual Impairment
Viewing strategies are strategies used to process visual Information. Many children with visual impairment seem to lack systematic viewing strategies.
- Trial name
- NCT05600140
- Testing
- Viewing strategy training
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Dutch Visio
Low Vision Blindness, Visual Impairment
Development of a Multi-sensory Rehabilitation Program for People With Ultra Low Vision
This research is aimed to address one of the big gaps in the current vision rehabilitation protocols for people with profound visual impairment by evaluating a multisensory approach.
- Conditions
- Low Vision Blindness, Visual Impairment, Quality of Life, Functional Visual Loss
- Trial name
- NCT05028712
- Testing
- Visual Information Training, Multimodal training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- State University of New York College of Optometry
Low Vision
Validation of a Virtual Reality Test for the Assessment of Visually Impaired Patients Undergoing Low Vision Rehabilitation
Low vision rehabilitation is a vital part of care for visually impaired patients, who are usually referred to orthoptists to develop visual strategies and optimize residual vision.
- Trial name
- VisionumVR (NCT07092124)
- Testing
- test visionumVR
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Low Vision
Obstacle Negotiation in Older People With and Without Vision Impairment
Falls are common among people with vision impairment and can lead to devastating health consequences. Understanding the functions of vision and how the visual characteristics of obstacles in the walking path impact the gait of…
- Trial name
- NCT05888441
- Testing
- Obstacle characteristics
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University