BreathlessnessNCT05625854
Using a Fan With Aromatherapy in Breathlessness Patients in Terminal Illness
A study testing Blow a fan to the face combine aromatherapy, Blow a fan to the face and Blow a fan to the feet in people with Breathlessness and Aromatherapy, run by Tsai-Wei Huang at 1 site in Taiwan.
Trial summary
Difficulty breathing is a very devastating symptom, often seen in terminal patients. Accompanied by physical, psychological, emotional, and social limitations, Not to mention the ambiguity in the occurrence of dyspnea symptoms and the difficulty in obtaining satisfactory quality of symptom care. Read more about this study
- Who is it for?
- Ages 20 years and older
- Conditions the study is for
- Breathlessness, Aromatherapy, Fans
- What is being tested?
- Blow a fan to the face combine aromatherapy, Blow a fan to the face and Blow a fan to the feet
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 26 participants
- Where
- 1 siteTaiwan
- Study dates
- 5 Aug 2021to 30 Apr 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Over 20 years old.
- It is determined by the physician to meet the final diagnosis conditions.
- Symptoms of dyspnea.
- The status of patients is assessed using the East Coast Cancer Clinical Research Cooperative Organization Assessment Scale (ECOG) ≧ 2 points.
- Able to communicate in Mandarin or Taiwanese or written conversation.
- Conscience clear.
- After explaining and explaining, agree to participate in this research and sign the consent form.
Who cannot join
- Receive treatment for facial trigeminal nerve damage.
- Abnormal sense of smell.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of Using a Fan With Aromatherapy in Breathlessness Patient in Terminally Illness: a Randomized Control Trial
Difficulty breathing is a very devastating symptom, often seen in terminal patients. Accompanied by physical, psychological, emotional, and social limitations, Not to mention the ambiguity in the occurrence of dyspnea symptoms and the difficulty in obtaining satisfactory quality of symptom care. The purpose of this study is to confirm the use of non-drug interventions in clinical situations, such as fans and aromatherapy to alleviate the complications of end-stage patients. The effectiveness of the symptoms of dyspnea.
Read the detailed description
Difficulty breathing is a very devastating symptom, often seen in terminal patients. Accompanied by physical, psychological, emotional, and social limitations, Not to mention the ambiguity in the occurrence of dyspnea symptoms and the difficulty in obtaining satisfactory quality of symptom care. The purpose of this study is to confirm the use of non-drug interventions in clinical situations, such as fans and aromatherapy to alleviate the complications of end-stage patients. The effectiveness of the symptoms of dyspnea.
Inclusion criteria
- Over 20 years old.
- It is determined by the physician to meet the final diagnosis conditions.
- Symptoms of dyspnea.
- The daily physical status of patients is assessed using the East Coast Cancer Clinical Research Cooperative Organization Assessment Scale (Eastern Cooperative Oncology Group, ECOG) ≧ 2 points.
- Able to communicate in Mandarin or Taiwanese or written conversation.
- Unconscious disorder.
- After explaining and explaining, agree to participate in this research and sign the consent form.
Exclusion criteria
- Receive treatment for facial trigeminal nerve damage.
- Abnormal sense of smell.
- Conditions
- Breathlessness, Aromatherapy, Fans, Terminal Illness
- Being tested
- Blow a fan to the face combine aromatherapy, Blow a fan to the face, Blow a fan to the feet
- Medical subject headings
- Dyspnea
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Blow a fan to the face combine aromatherapyBehavioural
Blow a fan with aromatherapy to the face
Blow a fan to the faceBehavioural
Blow a fan to the face
Blow a fan to the feetBehavioural
Blow a fan to the feet
| Study group | Role | What they receive |
|---|---|---|
| Blow a fan to the face combine aromatherapy | Experimental | Not described Receives: Behavioral: Blow a fan to the face combine aromatherapy |
| Blow a fan to the face | Experimental | Not described Receives: Behavioral: Blow a fan to the face |
| Blow a fan to the feet | Placebo comparator | Not described Receives: Behavioral: Blow a fan to the feet |
What is being measured
The primary outcome is the main question the study is designed to answer.
Chinese version of the Respiratory Distress Observation Scale，C-RDOS
RDOS is an eight-item ordinal scale designed to measure the presence and intensity of respiratory distress in adults. High score means high respiratory distress.
Measured: The score change up to three days.
Secondary outcomes (3)
Patient Health Questionnaire (PHQ-9)
The PHQ-9 is the depression module, which scores each of the nine DSM-IV criteria as "0" (not at all) to "3" (nearly every day). It has been validated for use in primary care.[2]
It is not a screening tool for depression but it is used to monitor the severity of depression and response to treatment. high score mean higher emotion distress.
Measured: The score change up to three days.
Chinese version of the Edmonton Symptom Assessment System，C-ESAS
The ESAS includes 11 symptoms: pain, tiredness, nausea, depression, anxiety, drowsiness, appetite, sleep, well-being, shortness of breath, and other. It uses a 0-10 numerical scale: 0 shows the absence of a symptom, and 10 shows the worst experience of the symptom.
Measured: The score change up to three days.
Smart bracelet_Heart rate variability (HRV)
HRV is the physiological phenomenon of the variation in the time interval between consecutive heartbeats in milliseconds. A normal, healthy heart does not tick evenly like a metronome, but instead, when looking at the milliseconds between heartbeats, there is constant variation.
Measured: Continue wear bracelet five days to record HRV data.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Nov 2022
- Study start5 Aug 2021
- Primary completion30 Apr 2023
- Study completion30 Apr 2023
Why it stopped: The study was terminated prior to reaching the planned sample size due to slow participant accrual. Recruitment was substantially hindered by the COVID-19 pandemic, which restricted access to hospice inpatient units, and by the inherent difficulty of
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for BreathlessnessStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 26 participants (actual)
Sponsor and investigators
- Lead sponsor
- Tsai-Wei Huang
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Tsai-Wei Huang, Taipei Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05625854
- Sponsor's protocol ID
- fan for dyspnea
- Status last verified
- Jun 2026
- First submitted
- 14 Sep 2021
- Last updated
- 26 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Using a Fan With Aromatherapy in Breathlessness Patient in Terminally Illness: a Randomized Control Trial
- ClinicalTrials.gov ID
- NCT05625854
- Acronym / sponsor ID
- fan for dyspnea
- Conditions
- Breathlessness, Aromatherapy, Fans, Terminal Illness
- Study type
- Interventional
- Recruitment status
- TerminatedReason stopped: The study was terminated prior to reaching the planned sample size due to slow participant accrual. Recruitment was substantially hindered by the COVID-19 pandemic, which restricted access to hospice inpatient units, and by the inherent difficulty of
- Enrolment
- 26 participants (actual)
- Lead sponsor
- Tsai-Wei HuangUniversity, hospital or other
- Study start
- 5 Aug 2021 (actual)
- Primary completion
- 30 Apr 2023 (actual)
- Study completion
- 30 Apr 2023 (actual)
- First posted
- 23 Nov 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Difficulty breathing is a very devastating symptom, often seen in terminal patients. Accompanied by physical, psychological, emotional, and social limitations, Not to mention the ambiguity in the occurrence of dyspnea symptoms and the difficulty in obtaining satisfactory quality of symptom care. The purpose of this study is to confirm the use of non-drug interventions in clinical situations, such as fans and aromatherapy to alleviate the complications of end-stage patients. The effectiveness of the symptoms of dyspnea.
Detailed description
Difficulty breathing is a very devastating symptom, often seen in terminal patients. Accompanied by physical, psychological, emotional, and social limitations, Not to mention the ambiguity in the occurrence of dyspnea symptoms and the difficulty in obtaining satisfactory quality of symptom care. The purpose of this study is to confirm the use of non-drug interventions in clinical situations, such as fans and aromatherapy to alleviate the complications of end-stage patients. The effectiveness of the symptoms of dyspnea.
Inclusion criteria
- Over 20 years old.
- It is determined by the physician to meet the final diagnosis conditions.
- Symptoms of dyspnea.
- The daily physical status of patients is assessed using the East Coast Cancer Clinical Research Cooperative Organization Assessment Scale (Eastern Cooperative Oncology Group, ECOG) ≧ 2 points.
- Able to communicate in Mandarin or Taiwanese or written conversation.
- Unconscious disorder.
- After explaining and explaining, agree to participate in this research and sign the consent form.
Exclusion criteria
- Receive treatment for facial trigeminal nerve damage.
- Abnormal sense of smell.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Blow a fan to the face combine aromatherapy | Experimental | Behavioral: Blow a fan to the face combine aromatherapy |
| Blow a fan to the face | Experimental | Behavioral: Blow a fan to the face |
| Blow a fan to the feet | Placebo comparator | Behavioral: Blow a fan to the feet |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- Over 20 years old.
- It is determined by the physician to meet the final diagnosis conditions.
- Symptoms of dyspnea.
- The status of patients is assessed using the East Coast Cancer Clinical Research Cooperative Organization Assessment Scale (ECOG) ≧ 2 points.
- Able to communicate in Mandarin or Taiwanese or written conversation.
Key exclusion criteria (2 listed)
- Receive treatment for facial trigeminal nerve damage.
- Abnormal sense of smell.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Blow a fan to the face combine aromatherapyBlow a fan with aromatherapy to the face | Behavioural | Blow a fan to the face combine aromatherapy |
| Blow a fan to the faceBlow a fan to the face | Behavioural | Blow a fan to the face |
| Blow a fan to the feetBlow a fan to the feet | Behavioural | Blow a fan to the feet |
Primary outcome
Chinese version of the Respiratory Distress Observation Scale，C-RDOS
Time frame: The score change up to three days.
RDOS is an eight-item ordinal scale designed to measure the presence and intensity of respiratory distress in adults. High score means high respiratory distress.
3 secondary outcomes
Patient Health Questionnaire (PHQ-9)
Time frame: The score change up to three days.
Chinese version of the Edmonton Symptom Assessment System，C-ESAS
Time frame: The score change up to three days.
Smart bracelet_Heart rate variability (HRV)
Time frame: Continue wear bracelet five days to record HRV data.
Results and safety
The study was stopped early (reason given: The study was terminated prior to reaching the planned sample size due to slow participant accrual. Recruitment was substantially hindered by the COVID-19 pandemic, which restricted access to hospice inpatient units, and by the inherent difficulty of). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Blow a fan to the face combine aromatherapy, Blow a fan to the face and Blow a fan to the feet in people with Breathlessness and Aromatherapy, run by Tsai-Wei Huang at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 26 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: The study was terminated prior to reaching the planned sample size due to slow participant accrual. Recruitment was substantially hindered by the COVID-19 pandemic, which restricted access to hospice inpatient units, and by the inherent difficulty of). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Chinese version of the Respiratory Distress Observation Scale，C-RDOS (time frame: The score change up to three days.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2026.