Clinical trials: Terminal Illness
Terminal Illness, End of Life
Elaboration of a Multi-dimensional Indicator of Quality in Palliative Care
The purpose of this study is to elaborate a multi-dimensional indicator of the quality in palliative care for patients of end-of-life.
- Trial name
- QUALI-PALLI (NCT02814682)
- Where
- France
- Volunteers
- 560 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Terminal Illness
Effect of a Decision Aid on Decision Making for Family Member's Disclosure of Terminal Illness
This study is a randomized controlled trial that will compare two arms: an experimental intervention group that receives a decision aid consisting of an educational video and targeted manual providing a protocol for the family…
- Trial name
- NCT00686673
- Testing
- Providing tailored message on disclosing terminal illness, Providing non-tailored message on pain control
- Where
- 14 sites in South Korea
- Volunteers
- 440 people
- Sponsor
- National Cancer Center, Korea
Terminal Illness
iLIVE Volunteer Study
The aim of this study is to develop and evaluate the implementation of an international volunteer training programme to support patients dying in the hospital setting and their families. It has the following objectives: 1.
- Trial name
- NCT04678310
- Testing
- Support from the hospital palliative and end of life care volunteer service (developed for this study).
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- University of Liverpool
Depressive Symptoms, Depression, Anxiety
Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness
Psychological and existential distress are a common cause of suffering among patients nearing the end of life, and a major reason for requesting medical aid in dying.
- Conditions
- Depressive Symptoms, Depression, Anxiety, Psychological Distress, Terminal Illness
- Trial name
- NCT04257227
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Ottawa Hospital Research Institute
Health Care Utilization, End Stage Disease
ACP Video Intervention for Patients With Life-Limiting Illness
The goal of this research is to increase patients' knowledge about advance care planning (ACP) discussions and hospice care for patients with serious illness receiving home-based care.
- Trial name
- NCT04778761
- Testing
- Home ACP Video
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Kidney Disease, Kidney Disease, Chronic
Rutgers University Study of the Genetics of Kidney Disease
The goal of this observational study is to learn more about how genes impact the risk of kidney disease. Anyone 18 or older living in the US is eligible, and a diagnosis of kidney disease is NOT required.
- Conditions
- Kidney Disease, Kidney Disease, Chronic, Kidney Disease, End-Stage, Kidney Diseases
- Trial name
- rugcc-kd (NCT07217535)
- Testing
- Saliva sample, Health surveys
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Kidney Disease, End-Stage
Evaluating the Use of the Qidni/D Hemodialysis System by Subjects With End-Stage Renal Disease
The main goal of this clinical study is to evaluate the safety of the Qidni/D Hemodialysis System in patients with end-stage renal disease.
- Trial name
- NCT06086470
- Testing
- Qidni/D Hemodialysis System
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Qidni Labs Inc.
Dementia, Persistent Vegetative State
A Study to Tailor Advance Directives
In this study, hospitalized patients will first be surveyed regarding their interest in a traditional advanced directive (AD) and then in a modified AD.
- Conditions
- Dementia, Persistent Vegetative State, Terminally Ill
- Trial name
- NCT00121004
- Testing
- Advance Directive Selection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Chicago
End Stage Disease
Feasability of Foot Reflexology to Alleviate Anxiety in Palliative Care Unit (RPASP)
The primary purpose of the study is to know if foot reflexology can be accepted by patients hospitalized in palliative unit care (assessed by the number of patient who accept to participate), and if it is feasible (assessed by…
- Trial name
- RPASP (NCT04561271)
- Testing
- foot reflexology, toucher massage
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Clermont-Ferrand
Terminal Illness
Family Talk Intervention in the Context of Specialised Palliative Home Care
This intervention study aims to evaluate a psychosocial family based intervention in clinical practice, the Family Talk Intervention (FTI), for families with dependent children affected by life-threatening/life-limiting illness…
- Trial name
- NCT05365919
- Testing
- Family Talk Intervention
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Ersta Sköndal University College
Renal Disease, End-Stage
Incremental Haemodialysis in Incident Patients
Background: Incremental hemodialysis (HD) is a starting regime for renal replacement therapy (RRT) adapted to each patient's necessities. It is mainly conditioned by the residual renal function (RRF).
- Trial name
- IHDIP (NCT03239808)
- Testing
- Incremental haemodialysis, Conventional haemodialysis
- Where
- 3 sites in Spain
- Volunteers
- 152 people
- Sponsor
- Fundación para la Formación e Investigación de los Profesionales de la Salud de Extremadura
Chronic Kidney Disease; End-Stage Renal Disease; Hemodialysis; Pain; Anxiety
Deep Breathing Relaxation and Lemongrass Aromatherapy on Pain
This randomized controlled trial aims to evaluate the effect of deep breathing relaxation combined with lemongrass aromatherapy on pain during arteriovenous fistula needle insertion and anxiety in hemodialysis patients.
- Trial name
- NCT07825974
- Testing
- Deep Breathing Relaxation, Lemongrass Aromatherapy
- Where
- Iraq
- Volunteers
- 190 people
- Sponsor
- University of Baghdad
Cancer, Terminal Disease
Occupational Therapy Modulates the Pain in Cancer Patient Under Palliative Care
Pain is one of the most incapacitating symptoms because it is a complex experience that includes sensory and emotional perceptions, in which sensory, affective, cognitive, behavioral, cultural and social characteristics interact.
- Conditions
- Cancer, Terminal Disease, Pain
- Trial name
- NCT02102178
- Testing
- Tapestry, Regular occupation therapy, Weaving a scarf on a nail frame
- Volunteers
- 58 people
- Sponsor
- Barretos Cancer Hospital
End-Stage Liver Disease
Surprise Question in End of Life (SeQuEL) Care and the Effect of Prompting Palliative Care Consultation: End-Stage Liver Disease
This is a single center randomized platform trial determining whether prompting consideration of palliative care consultation through the electronic health record impacts the number of palliative consultations placed and…
- Trial name
- SeQuEL (NCT06400498)
- Testing
- Prompted Palliative Care Consult
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Vanderbilt University Medical Center
Hepatic Encephalopathy.
Efficacy of Sildenafil in the Improvement of Cognition and Quality of Life in Patients With Cirrhosis of Liver. A Proof of Concept Study.
The study is being conducted to evaluate the efficacy of Sildenafil (a 5-phosphodiesterase inhibitor) as a means to improve the cognitive impairment encountered in patients of minimal hepatic encephalopathy (MHE) as proposed in…
- Trial name
- NCT02028429
- Testing
- Sildenafil.
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Febrile Illness Acute
Treatment of Febrile Infectious Disease Among Children in Hadera District Given the Final Diagnosis. Descriptive Study
Study goal - to describe pediatric patients with febrile disease that administered to the emergency department (ED) of hillel-yaffe hospital, according to arrival diagnosis, ED diagnosis, given therapy, and therapy concordance…
- Trial name
- NCT02313532
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Hillel Yaffe Medical Center
Terminal Illness, Critical Illness
Targeting Bias to Reduce Disparities in End of Life Care
This study aims to determine the ways in which clinician implicit racial biases affect clinician communication with family members of patients near the end of life and to test a novel physician training intervention to reduce the…
- Trial name
- BRiDgE-Sim (NCT05165888)
- Testing
- Communication and Bias Mitigation Training, Communication skills training
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Kidney Disease, End-Stage, End-stage Renal Disease
Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
A prospective, single-arm, multi-center post-market surveillance study of the BD® WavelinQ™ EndoAVF System for the Creation of Arteriovenous (AV) Fistula in Patients Requiring Dialysis.
- Conditions
- Kidney Disease, End-Stage, End-stage Renal Disease, Arteriovenous Fistula
- Trial name
- CONNECT-AV (NCT04634916)
- Testing
- EndoAVF Creation
- Where
- 17 sites in United States, Australia
- Volunteers
- 220 people
- Sponsor
- C. R. Bard
Renal Disease, End Stage, Palliative Care
Improving Medical Decision Making for Older Patients With End Stage Renal Disease
The overall objective of this study is to reduce the burden of chronic kidney disease (CKD) and its consequences for an aging U.S. population.
- Conditions
- Renal Disease, End Stage, Palliative Care, Decision Aids
- Trial name
- VIDEO-KD (NCT04347629)
- Testing
- Advance Care Planning Video Decision Aid
- Where
- 9 sites in United States
- Volunteers
- 456 people
- Sponsor
- Tufts Medical Center
Terminal Diseases, Terminal Care
Medical Assistance in Dying Requests in Pain Clinic
Terminally ill patients often suffer existentially. Terminally ill patients with existential pain may request medical aid in dying.
- Conditions
- Terminal Diseases, Terminal Care, Chronic Pain, Disability or Chronic Disease Leading to Disablement
- Trial name
- MAiD (NCT06802562)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Salem Anaesthesia Pain Clinic