Cardiac ArrestNCT05724914
Call to Door Timing in Out-of-hospital Cardiac Arrest
An observational study of Cardiac Arrest and Morality, run by Yonsei University at 1 site in South Korea.
Trial summary
The investigators aimed to investigate the effect of delayed hospitalization on the basis of the call time on the clinical outcomes of patients with OHCA patients using a nationwide OHCA registry. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Cardiac Arrest, Morality
- How many people
- 182,508 participants
- Where
- 1 siteSouth Korea
- Study dates
- 14 Feb 2023to 24 Oct 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Cardiac arrest with cardiopulmonary resuscitation
Who may be able to join
- Out-of-hospital cardiac arrest event
Who cannot join
- Arrest of non-cardiac origin
- Age < 18 years
- No any CPR
- Missing data on call time
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Clinical Impact in Patients With Delayed Hospitalization in Patients With Out-of-hospital Cardiac Arrest
The investigators aimed to investigate the effect of delayed hospitalization on the basis of the call time on the clinical outcomes of patients with OHCA patients using a nationwide OHCA registry.
Read the detailed description
According to "2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care", immediate call for the local emergency response number takes a key role in the OHCA as the CPR in community does not provide quality of in-hospital CPR. The strong recommendation of speedy transportation, however, does not provide time limitation, and evident data supporting benefit within certain minutes to transfer is lack through our best of search. Therefore, The investigators aimed to investigate the effect of delayed hospitalization on the basis of the call time on the clinical outcomes of patients with OHCA patients using a nationwide OHCA registry.
- Conditions
- Cardiac Arrest, Morality
- Keywords
- Cardiac arrest, Mortality, Timing
- Medical subject headings
- Heart Arrest
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Cardiac Arrest | Out-Of-Hospital Cardiac Arrest |
What is being measured
The primary outcome is the main question the study is designed to answer.
Death from any cause at hospital discharge
Death from any cause at hospital discharge
Measured: up to 30 days
Secondary outcomes (1)
Poor neurological outcomesat hospital discharge
poor neurological outcomes, which was defined as a Glasgow-Pittsburge Cerebral Performance Category value at hospital discharge
Measured: up to 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Feb 2023
- Study start14 Feb 2023
- Primary completion1 May 2023
- Study completion24 Oct 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Cardiac ArrestStudies of the same condition, open and under way.
- More trials run by Yonsei UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 182,508 participants (actual)
Sponsor and investigators
- Lead sponsor
- Yonsei University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, SungA Bae, Yonsei University
- Investigators
- Yongcheol Kim, MD, PhD, Principal investigator, Severance Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05724914
- Sponsor's protocol ID
- CtD timing
- Status last verified
- Oct 2023
- First submitted
- 23 Jan 2023
- Last updated
- 3 Nov 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Lee OH, Heo SJ, Kim MH, Park JW, Bae S, Kim M, Roh JW, Kim Y, Im E, Jung IH, Cho DK. Therapeutic hypothermia in patients with acute myocardial infarction complicated by out-of-hospital cardiac arrest. BMC Med. 2025 Mar 26;23(1):179. doi: 10.1186/s12916-025-03997-0.
PubMed 40140891
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Impact in Patients With Delayed Hospitalization in Patients With Out-of-hospital Cardiac Arrest
- ClinicalTrials.gov ID
- NCT05724914
- Acronym / sponsor ID
- CtD timing
- Conditions
- Cardiac Arrest, Morality
- Keywords
- Cardiac arrest, Mortality, Timing
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 182,508 participants (actual)
- Lead sponsor
- Yonsei UniversityUniversity, hospital or other
- Study start
- 14 Feb 2023 (actual)
- Primary completion
- 1 May 2023 (actual)
- Study completion
- 24 Oct 2023 (actual)
- First posted
- 13 Feb 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators aimed to investigate the effect of delayed hospitalization on the basis of the call time on the clinical outcomes of patients with OHCA patients using a nationwide OHCA registry.
Detailed description
According to "2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care", immediate call for the local emergency response number takes a key role in the OHCA as the CPR in community does not provide quality of in-hospital CPR. The strong recommendation of speedy transportation, however, does not provide time limitation, and evident data supporting benefit within certain minutes to transfer is lack through our best of search. Therefore, The investigators aimed to investigate the effect of delayed hospitalization on the basis of the call time on the clinical outcomes of patients with OHCA patients using a nationwide OHCA registry.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Cardiac Arrest | – | –Out-Of-Hospital Cardiac Arrest |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Cardiac arrest with cardiopulmonary resuscitation
Key inclusion criteria (1 listed)
- Out-of-hospital cardiac arrest event
Key exclusion criteria (4 listed)
- Arrest of non-cardiac origin
- Age < 18 years
- No any CPR
- Missing data on call time
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Death from any cause at hospital discharge
Time frame: up to 30 days
Death from any cause at hospital discharge
1 secondary outcome
Poor neurological outcomesat hospital discharge
Time frame: up to 30 days
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2023.
- Derived from this study: PubMed 40140891Lee OH, Heo SJ, Kim MH, Park JW, Bae S, Kim M, Roh JW, Kim Y, Im E, Jung IH, Cho DK. Therapeutic hypothermia in patients with acute myocardial infarction complicated by out-of-hospital cardiac arrest. BMC Med. 2025 Mar 26;23(1):179. doi: 10.1186/s12916-025-03997-0.
- Individual participant dataSharing planned: No
Related trials for Cardiac Arrest
RecruitingObservational study
AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM)
Cardiomyopathies, Cardiac Arrest
Active, not recruiting
Assessment of Combined CCM and ICD Device in HFrEF
Heart Failure, Heart Failure With Reduced Ejection Fraction
Not yet recruitingObservational study
CAROTID DOPPLER AND CEREBRAL OXIMERY IN POST CARDIAC ARREST ICU PATIENTS
Cardiac Arrest (CA), Carotid Doppler
Active, not recruitingPhase 3
The Danish Out-of-Hospital Cardiac Arrest Study
Out-Of-Hospital Cardiac Arrest, Post-Cardiac Arrest Syndrome
RecruitingObservational study
Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patients: Comparison With VentilO Algorithm
Cardiac Arrest (CA), Cardiogenic Shock
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Yongcheol Kim, MD, PhD principal investigator
Severance Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cardiac Arrest and Morality, run by Yonsei University at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Nov 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Death from any cause at hospital discharge (time frame: up to 30 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05724914, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2023.