SarcopeniaNCT05767541
Pilates Exercises Versus Resistance Exercises Among Geriatric Population With Sarcopenia
A study testing Pilates exercises and Resistance exercises in people with Sarcopenia, run by Dow University of Health Sciences at 2 sites in Pakistan.
Trial summary
The goal of this clinical trial is to compare the effectiveness of two exercises to improve physical functioning of older adults with sarcopenia. the primary aim of this RCT is: To measure the influence of pilates exercises versus resistance training in elderly with sarcopenia. Read more about this study
- Who is it for?
- Ages 60 to 70 years
- Conditions the study is for
- Sarcopenia
- What is being tested?
- Pilates exercises and Resistance exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 2 sitesPakistan
- Study dates
- 1 Oct 2022to 31 Jan 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Referred and screened patients with sarcopenia from medicine, family medicine and neurology OPD at Dow University Hospital Ojha Campus, Karachi.
- Patients from 60 to 70 years of age
- Both male and female.
- Patients who consent to participate
Who cannot join
- Being bedridden
- Implanted pacemaker
- Recent history of any fracture
- Patients with cognitive \& neurological impairment
- Already enrolled in any exercise intervention program
- Known case of patients with malignancy
- Patients on steroids
Trial locations and contacts
2 sites in 1 country.
Pakistan2 sites
Dow University of Health and Sciences
Karachi, Sindh, 74200
Dow University of Health and Sciences
Karachi
About this study
Official title: Comparative Effects of Pilates Exercises Versus Resistance Exercises on Measures of Physical Functioning Among Geriatric Population With Sarcopenia. a Randomized Clinical Trial
The goal of this clinical trial is to compare the effectiveness of two exercises to improve physical functioning of older adults with sarcopenia. the primary aim of this RCT is:
To measure the influence of pilates exercises versus resistance training in elderly with sarcopenia.
Read more
To introduce an affordable, effective and safe exercise care program, which prioritizes to make geriatric population independent.
Participants will be assessed for all outcome measures change at baseline and after 3 weeks following an exercise intervention. Participants enrolled in pilates exercise group will receive total of 9 exercises and participants enrolled in resistance exercise group will receive total of 8 exercises.
Read the detailed description
A total sample of 70 of geriatric population with sarcopenia will be collected from Dow University Hospital Ojha. Non-probability purposive sampling technique will be used. Participants will be screened and referred from medicine, family medicine and neurology OPD to physiotherapy OPD. Outcome measure assessment will be performed in all patients at two time points: baseline and follow up at the end of last session.
Outcome measures include short physical performance battery assessment tool (SPPB). Strength and gait are first evaluated by the ability to perform the tasks of getting up and sitting on a chair five consecutive times and performing the walking speed test (3 meters), Time up and go test, sit and reach test, and 2-minute step test as a measure of physical functioning.
After complete assessment at baseline all participants will be randomized to different treatment groups using 70 opaque sealed envelopes containing notes written with "new treatment" or "Standard treatment" on (n= 35 of each). The envelops will be scrambled before each participant allow to draw an envelope and thus find out in which group they will be allocated. Treatment will be provided to both groups. Group 1 will be provided with pilates exercises and group 2 will be provided with resistance exercises. Both groups will perform generalized warm up for up to 10 minutes at the beginning and 10 minutes of relaxation exercises at the end of treatment session.
- Conditions
- Sarcopenia
- Being tested
- Pilates exercises, Resistance exercises
- Keywords
- Sarcopenia, Resistance training, Exercise Movement Techniques
- Medical subject headings
- Sarcopenia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pilates exercisesOther
The Pilates technique consist of hundred, swimming, prone leg lift, single leg stretch, spine stretch forward, arm circles, imprint and release, one leg circles and mini squat.
Resistance exercisesOther
Resistance training include leg press, shoulder press, bench press, back arm press, seated row, knee extension, leg curl and seated calf raise
| Study group | Role | What they receive |
|---|---|---|
| Pilates group | Experimental | The Pilates technique consists of a series of low-impact exercises that build strength and flexibility throughout the body. All exercises performed 3 days in a week, 3 visits per week total of 9 sessions. In first week participants will perform 1 set of each exercise with 10 repetitions. In second week 2 sets of each exercise with 12 repetitions and in the third week both groups will perform 3 sets of each exercise with 15 repetitions with a rest interval of 2-3 minutes between sets. Receives: Other: Pilates exercises |
| Resistance group | Active comparator | Resistance exercises are anaerobic physical exercises, uses low number of repetitions with adjustable intensity contribute to hypertrophy of the muscle fibers and increase in muscle strength. All exercises performed 3 days in a week, 3 visits per week total of 9 sessions. In first week participants will perform 1 set of each exercise with 10 repetitions. In second week 2 sets of each exercise with 12 repetitions and in the third week both groups will perform 3 sets of each exercise with 15 repetitions with a rest interval of 2-3 minutes between sets. Receives: Other: Resistance exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
Short physical performance battery assessment tool.
The SPPB assesses physical performance through balance, strength, and gait.
.Each test is scored from 0 (inability to perform the task) to 4 points (best test performance).The SPPB total score ranges from 0 (worst performance) to 12 points (best performance) and categorically evaluates performance in the tests using three classes of scores: three classes: 0-6 points (poor performance), 7-9 points (moderate performance), and 10-12 points (good performance).
Measured: 3 weeks, change from baseline
Secondary outcomes (3)
Time up and go test
TIME UP AND GO TEST: To evaluate agility and dynamic balance this is essential for tasks that demands quick movements.
Measured: 3 weeks, change from baseline
sit and reach test
SIT AND REACH TEST: It determines the lower back and hamstring flexibility. Which is necessary for proper gait pattern, good posture and multiple movement task.
Measured: 3 weeks, change from baseline
2-minute step test
2-MINUTE STEP TEST: To assess aerobic fitness.
Measured: 3 weeks, change from baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Mar 2023
- Study start1 Oct 2022
- Primary completion2 Jan 2024
- Study completion31 Jan 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for SarcopeniaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Dow University of Health Sciences
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Syeda Ariba Shoaib, Dow University of Health Sciences
- Investigators
- Syeda Ariba Shoaib, Principal investigator, Dow University of Heath Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05767541
- Sponsor's protocol ID
- 2642
- Status last verified
- Feb 2025
- First submitted
- 24 Dec 2022
- Last updated
- 6 Feb 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Mueller D, Redkva PE, Fernando de Borba E, Barbosa SC, Krause MP, Gregorio da Silva S. Effect of mat vs. apparatus pilates training on the functional capacity of elderly women. J Bodyw Mov Ther. 2021 Jan;25:80-86. doi: 10.1016/j.jbmt.2020.11.012. Epub 2020 Nov 16.
PubMed 33714516
Study at a glance
From the registry record, last updated by the sponsor on 6 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Pilates Exercises Versus Resistance Exercises on Measures of Physical Functioning Among Geriatric Population With Sarcopenia. a Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT05767541
- Acronym / sponsor ID
- 2642
- Conditions
- Sarcopenia
- Keywords
- Sarcopenia, Resistance training, Exercise Movement Techniques
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Dow University of Health SciencesUniversity, hospital or other
- Study start
- 1 Oct 2022 (actual)
- Primary completion
- 2 Jan 2024 (actual)
- Study completion
- 31 Jan 2024 (actual)
- First posted
- 14 Mar 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to compare the effectiveness of two exercises to improve physical functioning of older adults with sarcopenia. the primary aim of this RCT is:
To measure the influence of pilates exercises versus resistance training in elderly with sarcopenia.
To introduce an affordable, effective and safe exercise care program, which prioritizes to make geriatric population independent.
Participants will be assessed for all outcome measures change at baseline and after 3 weeks following an exercise intervention. Participants enrolled in pilates exercise group will receive total of 9 exercises and participants enrolled in resistance exercise group will receive total of 8 exercises.
Detailed description
A total sample of 70 of geriatric population with sarcopenia will be collected from Dow University Hospital Ojha. Non-probability purposive sampling technique will be used. Participants will be screened and referred from medicine, family medicine and neurology OPD to physiotherapy OPD. Outcome measure assessment will be performed in all patients at two time points: baseline and follow up at the end of last session.
Outcome measures include short physical performance battery assessment tool (SPPB). Strength and gait are first evaluated by the ability to perform the tasks of getting up and sitting on a chair five consecutive times and performing the walking speed test (3 meters), Time up and go test, sit and reach test, and 2-minute step test as a measure of physical functioning.
After complete assessment at baseline all participants will be randomized to different treatment groups using 70 opaque sealed envelopes containing notes written with "new treatment" or "Standard treatment" on (n= 35 of each). The envelops will be scrambled before each participant allow to draw an envelope and thus find out in which group they will be allocated. Treatment will be provided to both groups. Group 1 will be provided with pilates exercises and group 2 will be provided with resistance exercises. Both groups will perform generalized warm up for up to 10 minutes at the beginning and 10 minutes of relaxation exercises at the end of treatment session.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Pilates group | Experimental | Other: Pilates exercisesThe Pilates technique consists of a series of low-impact exercises that build strength and flexibility throughout the body. All exercises performed 3 days in a week, 3 visits per week total of 9 sessions. In first week participants will perform 1 set of each exercise with 10 repetitions. In second week 2 sets of each exercise with 12 repetitions and in the third week both groups will perform 3 sets of each exercise with 15 repetitions with a rest interval of 2-3 minutes between sets. |
| Resistance group | Active comparator | Other: Resistance exercisesResistance exercises are anaerobic physical exercises, uses low number of repetitions with adjustable intensity contribute to hypertrophy of the muscle fibers and increase in muscle strength. All exercises performed 3 days in a week, 3 visits per week total of 9 sessions. In first week participants will perform 1 set of each exercise with 10 repetitions. In second week 2 sets of each exercise with 12 repetitions and in the third week both groups will perform 3 sets of each exercise with 15 repetitions with a rest interval of 2-3 minutes between sets. |
Who may qualify
- Ages
- 60 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Referred and screened patients with sarcopenia from medicine, family medicine and neurology OPD at Dow University Hospital Ojha Campus, Karachi.
- Patients from 60 to 70 years of age
- Both male and female.
- Patients who consent to participate
Key exclusion criteria (7 listed)
- Being bedridden
- Implanted pacemaker
- Recent history of any fracture
- Patients with cognitive \& neurological impairment
- Already enrolled in any exercise intervention program
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pilates exercisesThe Pilates technique consist of hundred, swimming, prone leg lift, single leg stretch, spine stretch forward, arm circles, imprint and release, one leg circles and mini squat. | Other | Pilates group |
| Resistance exercisesResistance training include leg press, shoulder press, bench press, back arm press, seated row, knee extension, leg curl and seated calf raise | Other | Resistance group |
Primary outcome
Short physical performance battery assessment tool.
Time frame: 3 weeks, change from baseline
The SPPB assesses physical performance through balance, strength, and gait. .Each test is scored from 0 (inability to perform the task) to 4 points (best test performance).The SPPB total score ranges from 0 (worst performance) to 12 points (best performance) and categorically evaluates performance in the tests using three classes of scores: three classes: 0-6 points (poor performance), 7-9 points (moderate performance), and 10-12 points (good performance).
3 secondary outcomes
Time up and go test
Time frame: 3 weeks, change from baseline
sit and reach test
Time frame: 3 weeks, change from baseline
2-minute step test
Time frame: 3 weeks, change from baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Feb 2025.
- Results publication: PubMed 33714516Mueller D, Redkva PE, Fernando de Borba E, Barbosa SC, Krause MP, Gregorio da Silva S. Effect of mat vs. apparatus pilates training on the functional capacity of elderly women. J Bodyw Mov Ther. 2021 Jan;25:80-86. doi: 10.1016/j.jbmt.2020.11.012. Epub 2020 Nov 16.
- Effect of mat vs. apparatus pilates training on the functional capacity of elderly womenLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Syeda Ariba Shoaib principal investigator
Dow University of Heath Sciences
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pilates exercises and Resistance exercises in people with Sarcopenia, run by Dow University of Health Sciences at 2 sites in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Short physical performance battery assessment tool. (time frame: 3 weeks, change from baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05767541, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Feb 2025.