Canine RetractionNCT05780788
Characterizing Orthodontic Tooth Movement With Photographic Scans
A study testing Monitoring Tooth Movement in people with Canine Retraction, run by UConn Health at 1 site in United States.
Trial summary
Characterizing orthodontic tooth movements in real time by using photographic scans to monitor teeth movement. The photographic scans will also be compared to 3D model scans. Canine retraction over the course of 1 orthodontic visit will be measured. Read more about this study
- Who is it for?
- Ages 11 years and olderHealthy volunteers can take part
- Conditions the study is for
- Canine Retraction
- What is being tested?
- Monitoring Tooth Movement
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteUnited States
- Study dates
- 31 Dec 2020to 30 Jun 2024
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 11 years and older
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Patients with fixed orthodontic appliances
- Treatment plan requiring extraction of at least one maxillary premolar
- Male and female
- Permanent dentition from first molar to first molar in the maxilla
- Teeth with normal crown morphology
- Fully erupted canines
- Above 11 years of age
- Patients with any cellular phone with a camera
Who cannot join
- Lack of extraction in orthodontic treatment plan
- Syndromic patients
- Cleft lip/palate patients
- Removable appliances
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Characterizing Orthodontic Tooth Movement in Real Time Using Dental Monitoring Scans: a Pilot Study
Characterizing orthodontic tooth movements in real time by using photographic scans to monitor teeth movement. The photographic scans will also be compared to 3D model scans. Canine retraction over the course of 1 orthodontic visit will be measured.
Read the detailed description
The accuracy and reliability of Dental Monitoring scans is be evaluated and compared to that of iTero digital scans during maxillary canine retraction. The magnitude and type of tooth movement occurring in a one month period in patients undergoing maxillary canine retraction will be measured. Patients undergoing orthodontic treatment in the Center for Orthodontic Care at UConn Health will be evaluated for the inclusion criteria. A total of twenty patients whose orthodontic treatment plan required extraction of at least one premolar in the maxillary arch will be recruited. The patient will be required to take photographs and video scans as dictated by Dental Monitoring (DM) on the first and final days of the study period (four weeks), while iTero scans are taken by the provider in clinic on these same days. Patient will also be periodically taking photographic scans at home using Dental Monitoring. The DM scans taken by the patient will be compared to the iTero digital scans taken by the provider. This can be done by superimposing the stereolithographic (STL) files created from each scan and assessing the amount of deviation between the 3D models. The types of tooth movement occurring during canine retraction in buccolingual, mesiodistal, and incisogingival planes will be quantified using Doctor Dashboard software available in DM. DM's 3D matching technology allows superimposition of teeth from each 3D model created per scan. Each tooth and its movements are graphed in a detailed manner to provide precise information about its type of movement.
- Conditions
- Canine Retraction
- Being tested
- Monitoring Tooth Movement
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Monitoring Tooth MovementDevice
Monitoring Canine Retraction
| Study group | Role | What they receive |
|---|---|---|
| Canine retraction arm | Experimental | Canine retraction Receives: Device: Monitoring Tooth Movement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Accuracy Between Patient-taken DM Scan and Provider-taken iTero Scan
Deviation between the photographic and intraoral scan will be measured via root mean square (RMS) in millimeters (mm).
Measured: Initial Deviation T0 (Baseline), Final Deviation T9 (34-37 days)
Secondary outcomes (4)
Tracking Maxillary Canine Tooth Movement (Displacement)
Magnitude of canine tooth movement for every 4-5 days during a one month period. Measurements will be done in mm in three planes of space. Measurement reported in mm at each timepoint is the cumulative movement up to that timpoint during the one month of monitoring of tooth movement.
Measured: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary First Molar Movement (Displacement)
Magnitude of maxillary first molar tooth movement for every 4-5 days during a one month period. Measurements will be done in mm in three planes of space.
Measured: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary Canine Tooth Movement (Rotation)
Magnitude of canine tooth movement for every 4-5 days during a one month period. Measurements will be done in degrees in three planes of space.
Measured: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary First Molar Displacement (Rotation)
Magnitude of maxillary first molar tooth movement for every 4-5 days during a one month period. Measurements will be done in degrees in three planes of space.
Measured: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Mar 2023
- Study start31 Dec 2020
- Primary completion20 Mar 2024
- Study completion30 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Other trials for Canine RetractionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- UConn Health
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Flavio Uribe, UConn Health
- Investigators
- Flavio Uribe, DDS, Principal investigator, UConn Health
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05780788
- Sponsor's protocol ID
- 21-113-2
- Status last verified
- Dec 2025
- First submitted
- 28 Feb 2023
- Last updated
- 17 Dec 2025
- Results posted
- Yes, on ClinicalTrials.gov
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Characterizing Orthodontic Tooth Movement in Real Time Using Dental Monitoring Scans: a Pilot Study
- ClinicalTrials.gov ID
- NCT05780788
- Acronym / sponsor ID
- 21-113-2
- Conditions
- Canine Retraction
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- UConn HealthUniversity, hospital or other
- Study start
- 31 Dec 2020 (actual)
- Primary completion
- 20 Mar 2024 (actual)
- Study completion
- 30 Jun 2024 (actual)
- First posted
- 23 Mar 2023 (actual)
- Results
- Posted 17 Dec 2025
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Characterizing orthodontic tooth movements in real time by using photographic scans to monitor teeth movement. The photographic scans will also be compared to 3D model scans. Canine retraction over the course of 1 orthodontic visit will be measured.
Detailed description
The accuracy and reliability of Dental Monitoring scans is be evaluated and compared to that of iTero digital scans during maxillary canine retraction. The magnitude and type of tooth movement occurring in a one month period in patients undergoing maxillary canine retraction will be measured. Patients undergoing orthodontic treatment in the Center for Orthodontic Care at UConn Health will be evaluated for the inclusion criteria. A total of twenty patients whose orthodontic treatment plan required extraction of at least one premolar in the maxillary arch will be recruited. The patient will be required to take photographs and video scans as dictated by Dental Monitoring (DM) on the first and final days of the study period (four weeks), while iTero scans are taken by the provider in clinic on these same days. Patient will also be periodically taking photographic scans at home using Dental Monitoring. The DM scans taken by the patient will be compared to the iTero digital scans taken by the provider. This can be done by superimposing the stereolithographic (STL) files created from each scan and assessing the amount of deviation between the 3D models. The types of tooth movement occurring during canine retraction in buccolingual, mesiodistal, and incisogingival planes will be quantified using Doctor Dashboard software available in DM. DM's 3D matching technology allows superimposition of teeth from each 3D model created per scan. Each tooth and its movements are graphed in a detailed manner to provide precise information about its type of movement.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Canine retraction arm | Experimental | Device: Monitoring Tooth MovementCanine retraction |
Who may qualify
- Ages
- 11 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (8 listed)
- Patients with fixed orthodontic appliances
- Treatment plan requiring extraction of at least one maxillary premolar
- Male and female
- Permanent dentition from first molar to first molar in the maxilla
- Teeth with normal crown morphology
Key exclusion criteria (4 listed)
- Lack of extraction in orthodontic treatment plan
- Syndromic patients
- Cleft lip/palate patients
- Removable appliances
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Monitoring Tooth MovementMonitoring Canine Retraction | Device | Canine retraction arm |
Primary outcome
Accuracy Between Patient-taken DM Scan and Provider-taken iTero Scan
Time frame: Initial Deviation T0 (Baseline), Final Deviation T9 (34-37 days)
Deviation between the photographic and intraoral scan will be measured via root mean square (RMS) in millimeters (mm).
4 secondary outcomes
Tracking Maxillary Canine Tooth Movement (Displacement)
Time frame: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary First Molar Movement (Displacement)
Time frame: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary Canine Tooth Movement (Rotation)
Time frame: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary First Molar Displacement (Rotation)
Time frame: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Dec 2025.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Individual participant dataSharing planned: No
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Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction
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Evaluation of Corticotomy-Assisted Canine Retraction Rate
Malocclusion, Corticotomy
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Accelerated Orthodontics With Alveolar Decortication Plus CGF Injection
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Flavio Uribe, DDS principal investigator
UConn Health
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Monitoring Tooth Movement in people with Canine Retraction, run by UConn Health at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 17 Dec 2025). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Accuracy Between Patient-taken DM Scan and Provider-taken iTero Scan (time frame: Initial Deviation T0 (Baseline), Final Deviation T9 (34-37 days)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Dec 2025.