Sedentary BehaviorNCT05790837
Workplace Intervention to Reduce Sitting Time: a Randomized Clinical Trial.
A study testing Computer prompt "Stand up for your Health®" in people with Sedentary Behavior and Office Workers, run by Universidad del Desarrollo at 1 site in Chile.
Trial summary
The goal of this randomized clinical trial is to determine the effect of the computer prompt to break sitting time in office workers. The main question is: What is the effect of the computer prompt "Stand Up for Your Health®" plus education on sitting time, musculoskeletal symptoms, cardiometabolic markers, and… Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Sedentary Behavior, Office Workers
- What is being tested?
- Computer prompt "Stand up for your Health®"
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 106 participants
- Where
- 1 siteChile
- Study dates
- 16 Sep 2023to 28 Jun 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- office workers over 18 years of age,
- Full-time employees (≥35 hours per week);
- Spend most of their workday sitting (> 60%). This will be initially self-reported and used as selection criteria prior to the initial consent and measurement visit. This will be later confirmed using accelerometers;
- Work in the same office place during the week; and
- Able to walk without using an assistive device or requiring the assistance of another person.
Who cannot join
- Pregnant women;
- Desktop workers using a height-adjustable workstation; and
- Office workers sufficiently active according to WHO criteria.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Workplace Intervention to Reduce Sitting Time, Decrease Musculoskeletal Symptoms, and Improve Cardiometabolic Markers in Sedentary Office Workers: a Randomized Clinical Trial.
The goal of this randomized clinical trial is to determine the effect of the computer prompt to break sitting time in office workers.
The main question is: What is the effect of the computer prompt "Stand Up for Your Health®" plus education on sitting time, musculoskeletal symptoms, cardiometabolic markers, and physical activity in office workers compared with only education? In addition, to determine the level of adherence to the intervention program by identifying barriers and facilitators referred by the participants.
The participants will be divided into two groups, the experimental and the control group. The participants in the experimental group will use the computer prompt on their desktop and receive information about sedentary behaviour, and the control group will receive only information. All participants will wear accelerometers for one week. The musculoskeletal symptoms and cardiometabolic markers will be measured at baseline, 3rd and 6th month.
Read the detailed description
Sedentary behaviour and physical inactivity are risk factors for noncommunicable diseases related to the work environment. The accumulation of sitting time during the workday is related to musculoskeletal symptoms and worse cardiometabolic indicators.
The purpose of this study is to determine the effect of the "Stand up for your Health®" computer app on sitting time, musculoskeletal symptoms, cardiometabolic markers, and physical activity in office workers. Also, to determine the adherence to the intervention program by identifying barriers and facilitators referred by the participants.
In this 2-arm randomized controlled trial, both groups will be recruited from educational establishments and will be measured at baseline, 3rd, and 6th months. The experimental group will be implementing the "Stand Up for Your Health®" computer app plus educational information, while the control group will only receive educational information.
The same measurements will be completed in both groups during a 6 months follow-up period: sedentary behaviour using the Actigraph accelerometers and the Occupational Sitting and Physical Activity Questionnaire (OSPAQ); musculoskeletal symptoms will be assessed by a pressure pain algometer and the Standardized Nordic Questionnaire of Perception of musculoskeletal Symptoms; and cardiometabolic markers and anthropometric measurements will also be assessed according to protocol.
- Conditions
- Sedentary Behavior, Office Workers
- Being tested
- Computer prompt "Stand up for your Health®"
- Keywords
- Sedentary Behavior, Sitting time, Physical activity, Musculoskeletal symptoms, Cardiometabolic biomarkers
- Medical subject headings
- Sedentary Behavior, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Computer prompt "Stand up for your Health®"Behavioural
The intervention group consists on the implementation of a desktop application "Stand up for your Health®" computer prompt following the model proposed by the Guide to Physical Activity at Work (34). This app works by showing reminders and asking users to pause their work activity and take an active break. Pauses can be customized and programmed according to the user's preference, allowing control of the time of each pause, between pauses, and the possibility of delaying or interrupting the pause. In this study, the "Stand up for your Health®" app will be scheduled to appear every 60 minutes on the workers' computers and each break will last for 2 minutes. During this resting period, the worker will see a notice or reminder on their screen with a countdown clock. The application allows you to postpone or interrupt directions.
| Study group | Role | What they receive |
|---|---|---|
| Computer prompt + Education (CP+E) | Experimental | The intervention group consists of the implementation of the desktop application "Stand up for your Health®" following the model proposed by the Guide to Physical Activity at Work plus education through an information leaflet Receives: Behavioral: Computer prompt "Stand up for your Health®" |
| Only Education (OE) | No intervention | The control group will receive only education through an information leaflet also following the guidelines of the Work Physical Activity Guide on indications to control the time sitting at work. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Sedentary behaviour (occupational sitting time) at baseline
Sedentary behaviour will be objectively assessed using accelerometers Actigraph GT3X per a period of one week. Data will be downloaded and analyzed with ActiLife software.
Occupational sitting time shall be measured subjectively using the Occupational Sitting and Physical Activity Questionnaire (OSPAQ).
Measured: During 1 week at T0 (baseline)
Sedentary behaviour (occupational sitting time) at 3rd month
Sedentary behaviour will be objectively assessed using accelerometers Actigraph GT3X per a period of one week. Data will be downloaded and analyzed with ActiLife software.
Occupational sitting time shall be measured subjectively using the Occupational Sitting and Physical Activity Questionnaire (OSPAQ).
Measured: During 1 week at T1 (3rd month)
Sedentary behaviour (occupational sitting time) at 6th month
Sedentary behaviour will be objectively assessed using accelerometers Actigraph GT3X per a period of one week. Data will be downloaded and analyzed with ActiLife software.
Occupational sitting time shall be measured subjectively using the Occupational Sitting and Physical Activity Questionnaire (OSPAQ).
Measured: During 1 week at T2 (6th month)
Secondary outcomes (13)
Cardiometabolic biomarkers - Fasting blood glucose
Cardiometabolic health outcomes will be carried out following the standardized protocol in this study population. Measurements of fasting blood glucose in milligrams per deciliter (mg/dL) will be collected in blood samples on an empty stomach in the workplace by a trained and certified health professional.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Fasting insulin
Cardiometabolic health outcomes will be carried out following the standardized protocol in this study population. Measurements of fasting insulin in milligrams per deciliter (mg/dL) will be collected in blood samples on an empty stomach in the workplace by a trained and certified health professional.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Cortisol
Cardiometabolic health outcomes will be carried out following the standardized protocol in this study population. Measurements of cortisol in micrograms per deciliter (mcg/dL)will be collected in blood samples on an empty stomach in the workplace by a trained and certified health professional.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Triglycerides
Cardiometabolic health outcomes will be carried out following the standardized protocol in this study population. Measurements of triglycerides in milligrams per deciliter (mg/dL) will be collected in blood samples on an empty stomach in the workplace by a trained and certified health professional.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Total cholesterol
Cardiometabolic health outcomes will be carried out following the standardized protocol in this study population. Measurements of total cholesterol in milligrams per deciliter (mg/dL) will be collected in blood sample on an empty stomach in the workplace by a trained and certified health professional.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Low density lipoprotein cholesterol
Cardiometabolic health outcomes will be carried out following the standardized protocol in this study population. Measurements of low-density lipoprotein (LDL) cholesterol will be collected in a blood sample on an empty stomach in the workplace by a trained and certified health professional.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - High density lipoprotein cholesterol
Cardiometabolic health outcomes will be carried out following the standardized protocol in this study population. Measurements of high-density lipoprotein (HDL) cholesterol will be collected in a blood sample on an empty stomach in the workplace by a trained and certified health professional.
Anthropometric measurements and blood pressure will be assessed in all participants.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Anthropometric measurements - Height
Anthropometric measurements outcomes will be carried out following the standardized protocol in this study population. Height in meters (m) will be measured using an altimeter.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Anthropometric measurements - Weight
Anthropometric measurements outcomes will be carried out following the standardized protocol in this study population. Weight in kilograms (kg) will be measured using a digital scale.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Anthropometric measurements - Waist Circumference
Anthropometric measurements outcomes will be carried out following the standardized protocol in this study population. Waist Circumference in centimeters (cm) will be measured using a tape measure.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Anthropometric measurements - Body Mass Index
Anthropometric measurements outcomes will be carried out following the standardized protocol in this study population. Body Mass Index (BMI) in kilograms per square meters (kg/m2) will be calculated using the weight and height outcome measures.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Musculoskeletal symptoms - Pain
A pressure pain threshold algometer shall be used as an objective measurement and will provide a quantitative measurement of sensory perception of mechanical stimuli in kilopascal (kPa) units.
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Musculoskeletal symptoms - Symptoms
The standardized Nordic Questionnaire of perception of musculoskeletal symptoms will be used as a subjective measurement, providing a numerical pain scale.
All measurements will be performed by a physiotherapist and following a standardized measurement procedure for office workers
Measured: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Mar 2023
- Study start16 Sep 2023
- Primary completion19 Jun 2024
- Study completion28 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (8)Papers the sponsor has linked to this study.
- Other trials for Sedentary BehaviorStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized parallel-group trial. The groups will be recruited from higher education institutions. The length of this study will be six months. Measurements shall be made for both groups at baseline, 3rd, and 6th months. The intervention group will receive the computer prompt "Stand up for your Health®" and information about sedentary behaviour. The computer prompt appears when the workers accumulate one hour the work front to screen. The break is two minutes, and one video with exercises starts with instructions for workers during this time. The control group will receive only information through the leaflet.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 106 participants (actual)
Sponsor and investigators
- Lead sponsor
- Universidad del Desarrollo
- Sponsor type
- University, hospital or other
- Collaborators
- Superintendencia de Seguridad Social - Gobierno de Chile
- Responsible party
- Principal investigator, Jaime Leppe Zamora, Universidad del Desarrollo
- Investigators
- Jaime E Leppe Zamora, PhD©, Principal investigator, Universidad del Desarrollo, Santiago, Region Metropolitana, Chile
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05790837
- Sponsor's protocol ID
- 280-2022
- Status last verified
- May 2025
- First submitted
- 6 Mar 2023
- Last updated
- 15 May 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Hadgraft NT, Winkler E, Climie RE, Grace MS, Romero L, Owen N, Dunstan D, Healy G, Dempsey PC. Effects of sedentary behaviour interventions on biomarkers of cardiometabolic risk in adults: systematic review with meta-analyses. Br J Sports Med. 2021 Feb;55(3):144-154. doi: 10.1136/bjsports-2019-101154. Epub 2020 Apr 8.
PubMed 32269058Taylor WC, Williams JR, Harris LE, Shegog R. Computer Prompt Software to Reduce Sedentary Behavior and Promote Physical Activity Among Desk-Based Workers: A Systematic Review. Hum Factors. 2023 Aug;65(5):891-908. doi: 10.1177/00187208211034271. Epub 2021 Aug 15.
PubMed 34392738Fernandez-Verdejo R, Suarez-Reyes M. [Physical inactivity versus sedentariness: analysis of the chilean national health survey 2016-2017]. Rev Med Chil. 2021 Jan;149(1):103-109. doi: 10.4067/S0034-98872021000100103. Spanish.
PubMed 34106141Ekelund U, Brown WJ, Steene-Johannessen J, Fagerland MW, Owen N, Powell KE, Bauman AE, Lee IM. Do the associations of sedentary behaviour with cardiovascular disease mortality and cancer mortality differ by physical activity level? A systematic review and harmonised meta-analysis of data from 850 060 participants. Br J Sports Med. 2019 Jul;53(14):886-894. doi: 10.1136/bjsports-2017-098963. Epub 2018 Jul 10.
PubMed 29991570Ekelund U, Tarp J, Steene-Johannessen J, Hansen BH, Jefferis B, Fagerland MW, Whincup P, Diaz KM, Hooker SP, Chernofsky A, Larson MG, Spartano N, Vasan RS, Dohrn IM, Hagstromer M, Edwardson C, Yates T, Shiroma E, Anderssen SA, Lee IM. Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis. BMJ. 2019 Aug 21;366:l4570. doi: 10.1136/bmj.l4570.
PubMed 31434697Parry SP, Coenen P, Shrestha N, O'Sullivan PB, Maher CG, Straker LM. Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers. Cochrane Database Syst Rev. 2019 Nov 17;2019(11):CD012487. doi: 10.1002/14651858.CD012487.pub2.
PubMed 31742666Nunes AMP, Moita JPAM, Espanha MMMR, Petersen KK, Arendt-Nielsen L. Pressure pain thresholds in office workers with chronic neck pain: A systematic review and meta-analysis. Pain Pract. 2021 Sep;21(7):799-814. doi: 10.1111/papr.13014. Epub 2021 May 6.
PubMed 33829681Waongenngarm P, Areerak K, Janwantanakul P. The effects of breaks on low back pain, discomfort, and work productivity in office workers: A systematic review of randomized and non-randomized controlled trials. Appl Ergon. 2018 Apr;68:230-239. doi: 10.1016/j.apergo.2017.12.003. Epub 2017 Dec 8.
PubMed 29409639
Study at a glance
From the registry record, last updated by the sponsor on 15 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Workplace Intervention to Reduce Sitting Time, Decrease Musculoskeletal Symptoms, and Improve Cardiometabolic Markers in Sedentary Office Workers: a Randomized Clinical Trial.
- ClinicalTrials.gov ID
- NCT05790837
- Acronym / sponsor ID
- 280-2022
- Conditions
- Sedentary Behavior, Office Workers
- Keywords
- Sedentary Behavior, Sitting time, Physical activity, Musculoskeletal symptoms, Cardiometabolic biomarkers
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 106 participants (actual)
- Lead sponsor
- Universidad del DesarrolloUniversity, hospital or other
- Collaborators
- Superintendencia de Seguridad Social - Gobierno de Chile
- Study start
- 16 Sep 2023 (actual)
- Primary completion
- 19 Jun 2024 (actual)
- Study completion
- 28 Jun 2024 (actual)
- First posted
- 30 Mar 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this randomized clinical trial is to determine the effect of the computer prompt to break sitting time in office workers.
The main question is: What is the effect of the computer prompt "Stand Up for Your Health®" plus education on sitting time, musculoskeletal symptoms, cardiometabolic markers, and physical activity in office workers compared with only education? In addition, to determine the level of adherence to the intervention program by identifying barriers and facilitators referred by the participants.
The participants will be divided into two groups, the experimental and the control group. The participants in the experimental group will use the computer prompt on their desktop and receive information about sedentary behaviour, and the control group will receive only information. All participants will wear accelerometers for one week. The musculoskeletal symptoms and cardiometabolic markers will be measured at baseline, 3rd and 6th month.
Detailed description
Sedentary behaviour and physical inactivity are risk factors for noncommunicable diseases related to the work environment. The accumulation of sitting time during the workday is related to musculoskeletal symptoms and worse cardiometabolic indicators.
The purpose of this study is to determine the effect of the "Stand up for your Health®" computer app on sitting time, musculoskeletal symptoms, cardiometabolic markers, and physical activity in office workers. Also, to determine the adherence to the intervention program by identifying barriers and facilitators referred by the participants.
In this 2-arm randomized controlled trial, both groups will be recruited from educational establishments and will be measured at baseline, 3rd, and 6th months. The experimental group will be implementing the "Stand Up for Your Health®" computer app plus educational information, while the control group will only receive educational information.
The same measurements will be completed in both groups during a 6 months follow-up period: sedentary behaviour using the Actigraph accelerometers and the Occupational Sitting and Physical Activity Questionnaire (OSPAQ); musculoskeletal symptoms will be assessed by a pressure pain algometer and the Standardized Nordic Questionnaire of Perception of musculoskeletal Symptoms; and cardiometabolic markers and anthropometric measurements will also be assessed according to protocol.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Randomized parallel-group trial. The groups will be recruited from higher education institutions. The length of this study will be six months. Measurements shall be made for both groups at baseline, 3rd, and 6th months. The intervention group will receive the computer prompt "Stand up for your Health®" and information about sedentary behaviour. The computer prompt appears when the workers accumulate one hour the work front to screen. The break is two minutes, and one video with exercises starts with instructions for workers during this time. The control group will receive only information through the leaflet.
| Arm | Type | Receives |
|---|---|---|
| Computer prompt + Education (CP+E) | Experimental | Behavioral: Computer prompt "Stand up for your Health®"The intervention group consists of the implementation of the desktop application "Stand up for your Health®" following the model proposed by the Guide to Physical Activity at Work plus education through an information leaflet |
| Only Education (OE) | No intervention | –The control group will receive only education through an information leaflet also following the guidelines of the Work Physical Activity Guide on indications to control the time sitting at work. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- office workers over 18 years of age,
- Full-time employees (≥35 hours per week);
- Spend most of their workday sitting (> 60%). This will be initially self-reported and used as selection criteria prior to the initial consent and measurement visit. This will be later confirmed using accelerometers;
- Work in the same office place during the week; and
- Able to walk without using an assistive device or requiring the assistance of another person.
Key exclusion criteria (3 listed)
- Pregnant women;
- Desktop workers using a height-adjustable workstation; and
- Office workers sufficiently active according to WHO criteria.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Computer prompt "Stand up for your Health®"The intervention group consists on the implementation of a desktop application "Stand up for your Health®" computer prompt following the model proposed by the Guide to Physical Activity at Work (34). This app works by showing reminders and asking users to pause their work activity and take an active break. Pauses can be customized and programmed according to the user's preference, allowing control of the time of each pause, between pauses, and the possibility of delaying or interrupting the pause. In this study, the "Stand up for your Health®" app will be scheduled to appear every 60 minutes on the workers' computers and each break will last for 2 minutes. During this resting period, the worker will see a notice or reminder on their screen with a countdown clock. The application allows you to postpone or interrupt directions. | Behavioural | Computer prompt + Education (CP+E) |
Primary outcome
Sedentary behaviour (occupational sitting time) at baseline
Time frame: During 1 week at T0 (baseline)
Sedentary behaviour will be objectively assessed using accelerometers Actigraph GT3X per a period of one week. Data will be downloaded and analyzed with ActiLife software. Occupational sitting time shall be measured subjectively using the Occupational Sitting and Physical Activity Questionnaire (OSPAQ).
Sedentary behaviour (occupational sitting time) at 3rd month
Time frame: During 1 week at T1 (3rd month)
Sedentary behaviour will be objectively assessed using accelerometers Actigraph GT3X per a period of one week. Data will be downloaded and analyzed with ActiLife software. Occupational sitting time shall be measured subjectively using the Occupational Sitting and Physical Activity Questionnaire (OSPAQ).
Sedentary behaviour (occupational sitting time) at 6th month
Time frame: During 1 week at T2 (6th month)
Sedentary behaviour will be objectively assessed using accelerometers Actigraph GT3X per a period of one week. Data will be downloaded and analyzed with ActiLife software. Occupational sitting time shall be measured subjectively using the Occupational Sitting and Physical Activity Questionnaire (OSPAQ).
13 secondary outcomes
Cardiometabolic biomarkers - Fasting blood glucose
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Fasting insulin
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Cortisol
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Triglycerides
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Total cholesterol
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - Low density lipoprotein cholesterol
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Cardiometabolic biomarkers - High density lipoprotein cholesterol
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Anthropometric measurements - Height
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Anthropometric measurements - Weight
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Anthropometric measurements - Waist Circumference
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Anthropometric measurements - Body Mass Index
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Musculoskeletal symptoms - Pain
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Musculoskeletal symptoms - Symptoms
Time frame: At T0 (baseline), T1 (3rd month) and T2 (6th month)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 May 2025.
- Background: PubMed 32269058Hadgraft NT, Winkler E, Climie RE, Grace MS, Romero L, Owen N, Dunstan D, Healy G, Dempsey PC. Effects of sedentary behaviour interventions on biomarkers of cardiometabolic risk in adults: systematic review with meta-analyses. Br J Sports Med. 2021 Feb;55(3):144-154. doi: 10.1136/bjsports-2019-101154. Epub 2020 Apr 8.
- Background: PubMed 34392738Taylor WC, Williams JR, Harris LE, Shegog R. Computer Prompt Software to Reduce Sedentary Behavior and Promote Physical Activity Among Desk-Based Workers: A Systematic Review. Hum Factors. 2023 Aug;65(5):891-908. doi: 10.1177/00187208211034271. Epub 2021 Aug 15.
- Background: PubMed 34106141Fernandez-Verdejo R, Suarez-Reyes M. [Physical inactivity versus sedentariness: analysis of the chilean national health survey 2016-2017]. Rev Med Chil. 2021 Jan;149(1):103-109. doi: 10.4067/S0034-98872021000100103. Spanish.
- Background: PubMed 29991570Ekelund U, Brown WJ, Steene-Johannessen J, Fagerland MW, Owen N, Powell KE, Bauman AE, Lee IM. Do the associations of sedentary behaviour with cardiovascular disease mortality and cancer mortality differ by physical activity level? A systematic review and harmonised meta-analysis of data from 850 060 participants. Br J Sports Med. 2019 Jul;53(14):886-894. doi: 10.1136/bjsports-2017-098963. Epub 2018 Jul 10.
- Background: PubMed 31434697Ekelund U, Tarp J, Steene-Johannessen J, Hansen BH, Jefferis B, Fagerland MW, Whincup P, Diaz KM, Hooker SP, Chernofsky A, Larson MG, Spartano N, Vasan RS, Dohrn IM, Hagstromer M, Edwardson C, Yates T, Shiroma E, Anderssen SA, Lee IM. Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis. BMJ. 2019 Aug 21;366:l4570. doi: 10.1136/bmj.l4570.
- Background: PubMed 31742666Parry SP, Coenen P, Shrestha N, O'Sullivan PB, Maher CG, Straker LM. Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers. Cochrane Database Syst Rev. 2019 Nov 17;2019(11):CD012487. doi: 10.1002/14651858.CD012487.pub2.
- Background: PubMed 33829681Nunes AMP, Moita JPAM, Espanha MMMR, Petersen KK, Arendt-Nielsen L. Pressure pain thresholds in office workers with chronic neck pain: A systematic review and meta-analysis. Pain Pract. 2021 Sep;21(7):799-814. doi: 10.1111/papr.13014. Epub 2021 May 6.
- Background: PubMed 29409639Waongenngarm P, Areerak K, Janwantanakul P. The effects of breaks on low back pain, discomfort, and work productivity in office workers: A systematic review of randomized and non-randomized controlled trials. Appl Ergon. 2018 Apr;68:230-239. doi: 10.1016/j.apergo.2017.12.003. Epub 2017 Dec 8.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Jaime E Leppe Zamora, PhD© principal investigator
Universidad del Desarrollo, Santiago, Region Metropolitana, Chile
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Computer prompt "Stand up for your Health®" in people with Sedentary Behavior and Office Workers, run by Universidad del Desarrollo at 1 site in Chile.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Chile. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Sedentary behaviour (occupational sitting time) at baseline (time frame: During 1 week at T0 (baseline)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05790837, which also lists 8 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 May 2025.