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Mood Disorder of Depressed TypeNCT05797428

The Effects of Logotherapy in Adolescents With Mood Disorders

A study testing logotherapy in people with Mood Disorder of Depressed Type, run by National Taiwan University Hospital at 1 site in Taiwan.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

Logotherapy can help people find their meaning in life and help people reduce their suicidal ideation. Suicide was the second leading cause of death for 15-24 year-olds. Logotherapy can increase exploration of meaning in life for adolescents and prevent them from attempting suicide. Read more about this study

Who is it for?
Ages 15 to 24 years
Conditions the study is for
Mood Disorder of Depressed Type
What is being tested?
logotherapy
Could I receive a placebo?
No, everyone receives an active treatment
How many people
120 participants
Where
1 siteTaiwan
Study dates
19 May 2023to 31 Jul 2025
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 15 to 24 years
  • All sexes
  • No healthy volunteers
  • Child, Adult

Who may be able to join

  • Patients with mood disorders (such as depression, bipolar disorder) diagnosed by a psychiatrist.
  • Patient Health Questionnaire-9 items (PHQ-9) score 5-19 points (indicating mild depression to moderate to severe depression)
  • Agree to participate in logotherapy
  • Able to participate in logotherapy

Who cannot join

  • Patients with severe emotional disorders who cannot participate in logotherapy.
  • Those who have severe psychopathological phenomena and cannot judge reality or those who are mentally deficient.
  • Those who have serious suicidal ideation or clear suicide plan are not suitable for interview

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Fan-Ko Sun, PhD contact

+886-2-33669702

sunfanko@ntu.edu.tw

Chun-Ying Chiang, PhD contact

+886-7-6151100 ext. 7724

chunying@isu.edu.tw

Taiwan1 site, 1 recruiting
  • Kaohsiung Chang Gung Memorial Hospital

    Kaohsiung City, Niaosong District, 833

    Fan-Ko Sun, PhD, 0952624135, sunfanko@ntu.edu.tw

    Recruiting

Other trials in Taiwan

About this study

Official title: The Effects of Logotherapy on Meaning in Life, Depression, Anxiety and Suicidal Ideation in Adolescents With Mood Disorders

Logotherapy can help people find their meaning in life and help people reduce their suicidal ideation. Suicide was the second leading cause of death for 15-24 year-olds. Logotherapy can increase exploration of meaning in life for adolescents and prevent them from attempting suicide. However, most research only explored the effects of logotherapy on meaning in life and depression in adolescents with mood disorders. There is a lack of research to explore the effects of logotherapy on anxiety and suicidal ideation in adolescents. Therefore, this study will explore the effects of logotherapy on meaning in life, depression, anxiety and suicidal ideation in adolescents with mood disorders. This study will carry on for two years and the sample will be recruited from the adolescents' outpatient clinic of psychiatric department in hospitals. The first and second year of the study will use a single-blind randomized controlled trial approach, the aim is to evaluate the short-term and longitudinal effects of logotherapy meaning in life, depression, anxiety and suicidal ideation in adolescents with mood disorders, the sample will collect 120 adolescents with mood disorders, and will use four instruments for testing the logotherapy intervention. The four instruments are: (1) Purpose in life Test, (2) Beck Depression Inventory II, (3) Beck Anxiety Inventory, (4) Beck Scale for Suicide Ideation. Data will be analyzed using the Statistic Package for the Social Science. The result of this study will be applied to the mental health team in the clinical psychiatric department for taking care of patients, and help adolescents with mood disorders to find their meaning in life, further, to reduce their depression, anxiety and suicidal ideation.

Read the detailed description

Logotherapy can help people find their meaning in life and help people reduce their suicidal ideation. Suicide was the second leading cause of death for 15-24 year-olds. Logotherapy can increase exploration of meaning in life for adolescents and prevent them from attempting suicide. However, most research only explored the effects of logotherapy on meaning in life and depression in adolescents with mood disorders. There is a lack of research to explore the effects of logotherapy on anxiety and suicidal ideation in adolescents. Therefore, this study will explore the effects of logotherapy on meaning in life, depression, anxiety and suicidal ideation in adolescents with mood disorders. This study will carry on for two years and the sample will be recruited from the adolescents' outpatient clinic of psychiatric department in hospitals. The first and second year of the study will use a single-blind randomized controlled trial approach, the aim is to evaluate the short-term and longitudinal effects of logotherapy meaning in life, depression, anxiety and suicidal ideation in adolescents with mood disorders, the sample will collect 120 adolescents with mood disorders, and will use four instruments for testing the logotherapy intervention. The four instruments are: (1) Purpose in life Test, (2) Beck Depression Inventory II, (3) Beck Anxiety Inventory, (4) Beck Scale for Suicide Ideation. Data will be analyzed using the Statistic Package for the Social Science.

The research process includes:

  1. Participant acceptance and signing consent: Referral by doctors from Chang Gung Hospitals and National Taiwan University Hospitals. Full-time research assistants will explain the purpose of the research, the research process, the confidentiality of data processing, and allow the individual to freely decide whether to participate without being forced, obtaining a signed consent form. Those who are under twenty-years-old will also obtain the consent of the legal representative.
  2. Pre-test: data collectors blinded single-blind study, the work-students who did not participate in the intervention measures will collect the patient's basic data sheet and four scales.
  3. Random assignment: The psychologist (co-host) randomly assigns the cases to the experimental group or the control group, and assigns the groups by means of a computer-generated random assignment table.
  4. Intervention: The experimental group received 6 interventions of logotherapy given by a full-time assistant, while the control group received routine outpatient treatment of general adolescent psychiatry.
  5. Posttest: Both the experimental group and the control group will collect the same four scales three times by the work-study students.

The result of this study will be applied to the mental health team in the clinical psychiatric department for taking care of patients, and help adolescents with mood disorders to find their meaning in life, further, to reduce their depression, anxiety and suicidal ideation.

Being tested
logotherapy
Keywords
logotherapy, depression, anxiety, suicidal ideation, adolescent
Medical subject headings
Depression, Anxiety Disorders, Suicidal Ideation

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • logotherapyOther

    The logotherapy is carried out in an individual way in this study. The full-time assistant will give the experimental group 3 months of logotherapy intervention by interviewing with the participant, once every two weeks, about 1-2 hours each time, a total of 6 times of logotherapy to guide the participant to find the meaning of his life and value.The location is mainly in the hospital when the participant has to return for consultation, or at the participant's home.

Study groups in NCT05797428
Study groupRoleWhat they receive
LogotherapyExperimental3 months of logotherapy intervention by interviewing with the participant, once every two weeks, about 1-2 hours each time, a total of 6 times of logotherapy.
Receives: Other: logotherapy
Routine psychiatric outpatient treatmentNo interventionWill not provide any logotherapy. Just routine psychiatric outpatient treatment.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Purpose in life Test-1

    There are 20 items in this scale, which are divided into four dimensions: quality of life, value of life, purpose of life, and freedom of life. Each question is scored on a scale of 1-5, and the total score ranges from 20-100, with higher scores representing a higher sense of meaning in life.

    Measured: pre-test (before intervention)

  2. Purpose in life Test-2

    There are 20 items in this scale, which are divided into four dimensions: quality of life, value of life, purpose of life, and freedom of life. Each question is scored on a scale of 1-5, and the total score ranges from 20-100, with higher scores representing a higher sense of meaning in life.

    Measured: post-test 1 (the week after the intervention)

  3. Purpose in life Test-3

    There are 20 items in this scale, which are divided into four dimensions: quality of life, value of life, purpose of life, and freedom of life. Each question is scored on a scale of 1-5, and the total score ranges from 20-100, with higher scores representing a higher sense of meaning in life.

    Measured: post-test 2 (three months after the intervention)

  4. Purpose in life Test-4

    There are 20 items in this scale, which are divided into four dimensions: quality of life, value of life, purpose of life, and freedom of life. Each question is scored on a scale of 1-5, and the total score ranges from 20-100, with higher scores representing a higher sense of meaning in life.

    Measured: post-test 3 (nine months after the intervention)

  5. Beck Depression Inventory II-1

    This scale has a total of 21 items. Each item is scored from 0-3 points, and the total score ranges from 0-63 points. The higher the score, the higher the degree of depression.

    Measured: pre-test (before intervention)

  6. Beck Depression Inventory II-2

    This scale has a total of 21 items. Each item is scored from 0-3 points, and the total score ranges from 0-63 points. The higher the score, the higher the degree of depression.

    Measured: post-test 1 (the week after the intervention)

  7. Beck Depression Inventory II-3

    This scale has a total of 21 items. Each item is scored from 0-3 points, and the total score ranges from 0-63 points. The higher the score, the higher the degree of depression.

    Measured: post-test 2 (three months after the intervention)

  8. Beck Depression Inventory II-4

    This scale has a total of 21 items. Each item is scored from 0-3 points, and the total score ranges from 0-63 points. The higher the score, the higher the degree of depression.

    Measured: post-test 3 (nine months after the intervention)

  9. Beck Anxiety Inventory-1

    This scale contains 21 items and each item is scored from 0-3 points. The total score ranges from 0-63 points. The higher the score, the higher the degree of anxiety.

    Measured: pre-test (before intervention)

  10. Beck Anxiety Inventory-2

    This scale contains 21 items and each item is scored from 0-3 points. The total score ranges from 0-63 points. The higher the score, the higher the degree of anxiety.

    Measured: post-test 1 (the week after the intervention)

  11. Beck Anxiety Inventory-3

    This scale contains 21 items and each item is scored from 0-3 points. The total score ranges from 0-63 points. The higher the score, the higher the degree of anxiety.

    Measured: post-test 2 (three months after the intervention)

  12. Beck Anxiety Inventory-4

    This scale contains 21 items and each item is scored from 0-3 points. The total score ranges from 0-63 points. The higher the score, the higher the degree of anxiety.

    Measured: post-test 3 (nine months after the intervention)

  13. Beck Scale for Suicide Ideation-1

    This scale contains 21 items. The first 19 items mainly measure the severity of the individual's attitudes, behaviors, and plans for suicide in the past week. Each question is calculated on a scale of 0-2, and the total score ranges from 0-38, with higher scores indicating stronger suicidal ideation. The last two questions, which are not counted, ask about the number of previous suicide attempts and the severity of the intention of the last suicide attempt.

    Measured: pre-test (before intervention)

  14. Beck Scale for Suicide Ideation-2

    This scale contains 21 items. The first 19 items mainly measure the severity of the individual's attitudes, behaviors, and plans for suicide in the past week. Each question is calculated on a scale of 0-2, and the total score ranges from 0-38, with higher scores indicating stronger suicidal ideation. The last two questions, which are not counted, ask about the number of previous suicide attempts and the severity of the intention of the last suicide attempt.

    Measured: post-test 1 (the week after the intervention)

  15. Beck Scale for Suicide Ideation-3

    This scale contains 21 items. The first 19 items mainly measure the severity of the individual's attitudes, behaviors, and plans for suicide in the past week. Each question is calculated on a scale of 0-2, and the total score ranges from 0-38, with higher scores indicating stronger suicidal ideation. The last two questions, which are not counted, ask about the number of previous suicide attempts and the severity of the intention of the last suicide attempt.

    Measured: post-test 2 (three months after the intervention)

  16. Beck Scale for Suicide Ideation-4

    This scale contains 21 items. The first 19 items mainly measure the severity of the individual's attitudes, behaviors, and plans for suicide in the past week. Each question is calculated on a scale of 0-2, and the total score ranges from 0-38, with higher scores indicating stronger suicidal ideation. The last two questions, which are not counted, ask about the number of previous suicide attempts and the severity of the intention of the last suicide attempt.

    Measured: post-test 3 (nine months after the intervention)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted4 Apr 2023
  2. Study start19 May 2023
  3. Primary completion31 Jul 2025 (estimated)
  4. Study completion31 Jul 2025 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Randomised
Intervention model
Parallel groups
Masking
Double blind
Who is masked
Participant, Outcomes assessor
Enrolment
120 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT05797428
Sponsor's protocol ID
202212025RINA
Status last verified
Feb 2025
First submitted
20 Mar 2023
Last updated
18 Mar 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing logotherapy in people with Mood Disorder of Depressed Type, run by National Taiwan University Hospital at 1 site in Taiwan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 18 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Fan-Ko Sun, PhD (+886-2-33669702, sunfanko@ntu.edu.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Purpose in life Test-1 (time frame: pre-test (before intervention)). The study lists 16 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Mar 2025.

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