Sportive PerformanceNCT05916352
Effects of Caffeine on Upper Extremity Performance
A study testing Caffeine Supplement in people with Sportive Performance and Caffeine, run by Cyprus International University at 1 site in Turkey (Türkiye).
Trial summary
It was aimed to apply caffeine supplement to elite basketball players and to investigate the effects of this supplement on upper extremity performance, lactic acid level and fatigue. The investigators also aimed to investigate the effects of blood lactate level on performance and fatigue. Read more about this study
- Who is it for?
- Ages 19 to 44 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Sportive Performance, Caffeine
- What is being tested?
- Caffeine Supplement
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 50 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 4 Jul 2022to 6 Jun 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 to 44 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Elite basketball players aged 19-44
- Individuals with caffeine consumption below 2 mg per kg per day
Who cannot join
- Individuals with systemic disease affecting the musculoskeletal system
- Individuals using supplements containing caffeine
- Individuals with any diagnosed neurological or orthopedic disease
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of Caffeine Supplementation on Blood Lactate Level, Performance and Post-Training Fatigue in Elite Basketball Players
It was aimed to apply caffeine supplement to elite basketball players and to investigate the effects of this supplement on upper extremity performance, lactic acid level and fatigue. The investigators also aimed to investigate the effects of blood lactate level on performance and fatigue.
Read the detailed description
The aim of this study is to examine the effects of caffeine supplementation on upper extremity performance, lactic acid and fatigue in elite basketball players and compare them with the placebo group. A total of 50 elite basketball players, 25 each in the caffeine and placebo groups, will participate in the study. Caffeine supplement will be given 1 hour before the measurements (5mg/kg). Muscular endurance before and after reinforcement, scapular muscular endurance test (SKET); arm movement speed, disc touch test (DDT); anaerobic power, medicine ball throwing (STF); lactic acid (LA) level will be evaluated by finger blood measurement and fatigue visual analog scale (VAS).
- Conditions
- Sportive Performance, Caffeine
- Being tested
- Caffeine Supplement
- Keywords
- Caffeine, Performance, Lactic Acid, Basketball, Fatigue
- Medical subject headings
- Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Caffeine SupplementDietary supplement
Caffeine tablet
| Study group | Role | What they receive |
|---|---|---|
| Caffeine Group | Active comparator | 5 mg/kg caffein supplement will be given Receives: Dietary Supplement: Caffeine Supplement |
| Placebo Group | Placebo comparator | Placebo will be given Receives: Dietary Supplement: Caffeine Supplement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Blood Lactate Level
Lactic acid level in the blood
Measured: 2 hours
Secondary outcomes (4)
Reaction Time
Arm movement speed
Measured: 5 minutes
Anaerobic Power
Upper extremity explosive force will be measured with medicine ball
Measured: 5 minutes
Muscular Endurance
Endurance time will be measured using a 1 kg Dynamometer.
Measured: 5 minutes
Fatigue
Subjective fatigue will be measured using the Visual Analog Scale which ranging from 0 to 10 points. A value of 0 describes "no pain" and a value of 10 describes the "most pain".
Measured: 1 minute
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jun 2023
- Study start4 Jul 2022
- Primary completion14 Oct 2022
- Study completion6 Jun 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (8)Papers the sponsor has linked to this study.
- Other trials for Sportive PerformanceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- The research is a double-blind randomized controlled comparative cross-sectional study.
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cyprus International University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Prof. Dr. Sıddıka Fatma Uygur, Cyprus International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05916352
- Sponsor's protocol ID
- -020-7249
- Status last verified
- Jul 2023
- First submitted
- 7 Jun 2023
- Last updated
- 2 Aug 2023
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The individual participant data obtained from the participants will be shared in the form of thesis and scientific articles.
Publications
Ben Abdelkrim N, Castagna C, El Fazaa S, Tabka Z, El Ati J. Blood metabolites during basketball competitions. J Strength Cond Res. 2009 May;23(3):765-73. doi: 10.1519/JSC.0b013e3181a2d8fc.
PubMed 19387403Spriet LL. Exercise and sport performance with low doses of caffeine. Sports Med. 2014 Nov;44 Suppl 2(Suppl 2):S175-84. doi: 10.1007/s40279-014-0257-8.
PubMed 25355191Burke LM. Practical Issues in Evidence-Based Use of Performance Supplements: Supplement Interactions, Repeated Use and Individual Responses. Sports Med. 2017 Mar;47(Suppl 1):79-100. doi: 10.1007/s40279-017-0687-1.
PubMed 28332111Caravan I, Sevastre Berghian A, Moldovan R, Decea N, Orasan R, Filip GA. Modulatory effects of caffeine on oxidative stress and anxiety-like behavior in ovariectomized rats. Can J Physiol Pharmacol. 2016 Sep;94(9):961-72. doi: 10.1139/cjpp-2015-0502. Epub 2016 Apr 16.
PubMed 27333093Chia JS, Barrett LA, Chow JY, Burns SF. Effects of Caffeine Supplementation on Performance in Ball Games. Sports Med. 2017 Dec;47(12):2453-2471. doi: 10.1007/s40279-017-0763-6.
PubMed 28741186Grgic J, Trexler ET, Lazinica B, Pedisic Z. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis. J Int Soc Sports Nutr. 2018 Mar 5;15:11. doi: 10.1186/s12970-018-0216-0. eCollection 2018.
PubMed 29527137Sant'Ana J, Franchini E, da Silva V, Diefenthaeler F. Effect of fatigue on reaction time, response time, performance time, and kick impact in taekwondo roundhouse kick. Sports Biomech. 2017 Jun;16(2):201-209. doi: 10.1080/14763141.2016.1217347. Epub 2016 Sep 5.
PubMed 27592682San Juan AF, Lopez-Samanes A, Jodra P, Valenzuela PL, Rueda J, Veiga-Herreros P, Perez-Lopez A, Dominguez R. Caffeine Supplementation Improves Anaerobic Performance and Neuromuscular Efficiency and Fatigue in Olympic-Level Boxers. Nutrients. 2019 Sep 5;11(9):2120. doi: 10.3390/nu11092120.
PubMed 31492050
Study at a glance
From the registry record, last updated by the sponsor on 2 Aug 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Caffeine Supplementation on Blood Lactate Level, Performance and Post-Training Fatigue in Elite Basketball Players
- ClinicalTrials.gov ID
- NCT05916352
- Acronym / sponsor ID
- -020-7249
- Conditions
- Sportive Performance, Caffeine
- Keywords
- Caffeine, Performance, Lactic Acid, Basketball, Fatigue
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Cyprus International UniversityUniversity, hospital or other
- Study start
- 4 Jul 2022 (actual)
- Primary completion
- 14 Oct 2022 (actual)
- Study completion
- 6 Jun 2023 (actual)
- First posted
- 23 Jun 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
It was aimed to apply caffeine supplement to elite basketball players and to investigate the effects of this supplement on upper extremity performance, lactic acid level and fatigue. The investigators also aimed to investigate the effects of blood lactate level on performance and fatigue.
Detailed description
The aim of this study is to examine the effects of caffeine supplementation on upper extremity performance, lactic acid and fatigue in elite basketball players and compare them with the placebo group. A total of 50 elite basketball players, 25 each in the caffeine and placebo groups, will participate in the study. Caffeine supplement will be given 1 hour before the measurements (5mg/kg). Muscular endurance before and after reinforcement, scapular muscular endurance test (SKET); arm movement speed, disc touch test (DDT); anaerobic power, medicine ball throwing (STF); lactic acid (LA) level will be evaluated by finger blood measurement and fatigue visual analog scale (VAS).
Study design
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
- Model description
- The research is a double-blind randomized controlled comparative cross-sectional study.
| Arm | Type | Receives |
|---|---|---|
| Caffeine Group | Active comparator | Dietary Supplement: Caffeine Supplement5 mg/kg caffein supplement will be given |
| Placebo Group | Placebo comparator | Dietary Supplement: Caffeine SupplementPlacebo will be given |
Who may qualify
- Ages
- 19 to 44 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Elite basketball players aged 19-44
- Individuals with caffeine consumption below 2 mg per kg per day
Key exclusion criteria (3 listed)
- Individuals with systemic disease affecting the musculoskeletal system
- Individuals using supplements containing caffeine
- Individuals with any diagnosed neurological or orthopedic disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Caffeine SupplementCaffeine tablet | Dietary supplement | Caffeine Group, Placebo Group |
Primary outcome
Blood Lactate Level
Time frame: 2 hours
Lactic acid level in the blood
4 secondary outcomes
Reaction Time
Time frame: 5 minutes
Anaerobic Power
Time frame: 5 minutes
Muscular Endurance
Time frame: 5 minutes
Fatigue
Time frame: 1 minute
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Aug 2023.
- Results publication: PubMed 19387403Ben Abdelkrim N, Castagna C, El Fazaa S, Tabka Z, El Ati J. Blood metabolites during basketball competitions. J Strength Cond Res. 2009 May;23(3):765-73. doi: 10.1519/JSC.0b013e3181a2d8fc.
- Results publication: PubMed 25355191Spriet LL. Exercise and sport performance with low doses of caffeine. Sports Med. 2014 Nov;44 Suppl 2(Suppl 2):S175-84. doi: 10.1007/s40279-014-0257-8.
- Results publication: PubMed 28332111Burke LM. Practical Issues in Evidence-Based Use of Performance Supplements: Supplement Interactions, Repeated Use and Individual Responses. Sports Med. 2017 Mar;47(Suppl 1):79-100. doi: 10.1007/s40279-017-0687-1.
- Results publication: PubMed 27333093Caravan I, Sevastre Berghian A, Moldovan R, Decea N, Orasan R, Filip GA. Modulatory effects of caffeine on oxidative stress and anxiety-like behavior in ovariectomized rats. Can J Physiol Pharmacol. 2016 Sep;94(9):961-72. doi: 10.1139/cjpp-2015-0502. Epub 2016 Apr 16.
- Results publication: PubMed 28741186Chia JS, Barrett LA, Chow JY, Burns SF. Effects of Caffeine Supplementation on Performance in Ball Games. Sports Med. 2017 Dec;47(12):2453-2471. doi: 10.1007/s40279-017-0763-6.
- Results publication: PubMed 29527137Grgic J, Trexler ET, Lazinica B, Pedisic Z. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis. J Int Soc Sports Nutr. 2018 Mar 5;15:11. doi: 10.1186/s12970-018-0216-0. eCollection 2018.
- Results publication: PubMed 27592682Sant'Ana J, Franchini E, da Silva V, Diefenthaeler F. Effect of fatigue on reaction time, response time, performance time, and kick impact in taekwondo roundhouse kick. Sports Biomech. 2017 Jun;16(2):201-209. doi: 10.1080/14763141.2016.1217347. Epub 2016 Sep 5.
- Results publication: PubMed 31492050San Juan AF, Lopez-Samanes A, Jodra P, Valenzuela PL, Rueda J, Veiga-Herreros P, Perez-Lopez A, Dominguez R. Caffeine Supplementation Improves Anaerobic Performance and Neuromuscular Efficiency and Fatigue in Olympic-Level Boxers. Nutrients. 2019 Sep 5;11(9):2120. doi: 10.3390/nu11092120.
- Individual participant dataSharing planned: Yes. The individual participant data obtained from the participants will be shared in the form of thesis and scientific articles.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Caffeine Supplement in people with Sportive Performance and Caffeine, run by Cyprus International University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Aug 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Blood Lactate Level (time frame: 2 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05916352, which also lists 8 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Aug 2023.