Clinical trials: Caffeine
Caffeine, Ischemic Preconditioning
The Effect of Caffeine on Ischemic Preconditioning
Ischaemic preconditioning (IP) describes the phenomenon that brief periods of ischaemia render the (myocardial) muscle more resistant to a subsequent more prolonged period of ischaemia and reperfusion.
- Conditions
- Caffeine, Ischemic Preconditioning, Ischemia-Reperfusion Injury
- Trial name
- NCT00184912
- Testing
- caffeine, Technetium-TC99m-labeled Annexin A5, ten minutes forearm ischemia
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Schizophrenia, Caffeine
The Impact of Caffeine on Cognition in Schizophrenia
Caffeine is the most used psychoactive drug in Canada, with regular consumption by 88% of the adult population, While rates of caffeine consumption are considered to be high in the general population, there is some evidence that…
- Trial name
- NCT02832401
- Testing
- Caffeine
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Type 2 Diabetes Nonalcoholic Fatty Liver
The Effects of Coffee Main Constituents (Caffeine and Chlorogenic Acid) Supplementation on Inflammatory, Metabolic Factors, Hepatic Steatosis and Fibrosis in None- Alcoholic Fatty Liver Patients With Type 2 Diabetes
The purpose of this study is to investigate the effects of coffee main constituents (caffeine and chlorogenic acid) supplements on inflammatory, metabolic factors, hepatic steatosis and fibrosis in none- alcoholic fatty liver…
- Trial name
- NCT02929901
- Testing
- caffeine and chlorogenic acid, caffeine, chlorogenic acid
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- National Nutrition and Food Technology Institute
Long COVID-19 Syndrome, Chronic Fatigue Syndrome
A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial
IRB approval date 14-APR-2024 and public at https://plataformabrasil.saude.gov.br/login.jsf since IURB approval Long COVID is a multi-systemic condition comprising often severe and persistent symptoms (longer than 12 weeks) that…
- Trial name
- REVIVE (NCT06128967)
- Testing
- Fluvoxamine Maleate 100 MG, Metformin Extended Release Oral Tablet
- Where
- 6 sites in Brazil
- Volunteers
- 399 people
- Sponsor
- Cardresearch
Acute Exercise, Caffeine Withdrawal
The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation
To determine the effects of moderate intensity exercise and caffeine on working memory in deprived caffeine consumers.
- Conditions
- Acute Exercise, Caffeine Withdrawal, Memory Deficits
- Trial name
- NCT05170464
- Testing
- Acute Exercise, Caffeine Powder
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Obesity
"Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat
This study compares four treatments to see which one causes the most weight loss, fat loss, loss of abdominal fat and improvement in blood tests like cholesterol.
- Trial name
- NCT00377975
- Testing
- Ephedrine, Pioglitazone, Caffeine
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Volleyball Players, Performance
Caffeinated Gum Use and Volleyball Performance
This study examined the acute effects of caffeinated chewing gum on volleyball performance in trained female volleyball players.
- Trial name
- NCT07597265
- Testing
- Single-dose caffeinated gum, Partial-dose caffeinated gum
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ege University
Alcohol or Other Drugs Effects
Combined Effects of Alcohol and Caffeine
The purpose of this study is to investigate the effects of caffeine on the self-administration of alcohol. The study will also examine the combined effects of alcohol and caffeine on behavioral performance, participant ratings of…
- Trial name
- NCT01289561
- Testing
- Alcohol + Caffeine Beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Premature Atrial Contractions, Premature Ventricular Contractions
Coffee and Real-time Atrial and Ventricular Ectopy
Atrial fibrillation (AF) and heart failure (HF) are morbid, costly, and incompletely understood diseases that have reached epidemic proportions worldwide.
- Trial name
- CRAVE (NCT03671759)
- Testing
- Start: On Caffeine, Start: Off Caffeine
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Food Insecurity, Undernutrition
Randomized Evaluation of Voucher Interventions for Value and Effectiveness (REVIVE) in Philippines
This study aims to evaluate whether revised food voucher programs, combined with nutrition education sessions, can improve food security, dietary quality, nutrition knowledge, and nutritional outcomes among low-income households…
- Conditions
- Food Insecurity, Undernutrition, Diet Quality, Nutrition Knowledge
- Trial name
- REVIVE (NCT07640594)
- Testing
- Food Voucher + SBCC (PhP 3,000), Food Voucher + SBCC (PhP 5,000), Food Voucher + SBCC (PhP 8,000)
- Where
- United States
- Volunteers
- 5,320 people
- Sponsor
- International Food Policy Research Institute
Athletes
The Acute Effects of Combined Caffeine and Sodium Bicarbonate Consumption on Isometric Mid-thigh Pull
The aim of this study was to investigate the effects of isolated and combined caffeine and sodium bicarbonate consumption on acute isometric mid-thigh pull (IMTP) strength, and verify whether they are cumulative, neutral or…
- Trial name
- NCT05883046
- Testing
- Performance-Enhancing Substances, Baseline (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bozok University
Fall, Fall Injury
A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients
Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls.
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- ADFICE_IT (NCT05449470)
- Testing
- CDSS, Patient Portal
- Where
- 10 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Supplementation, Sports Nutrition
Caffeine Kinetics and CrossFit®-Specific Performance
The study aims at assessing the relation between caffeine (CAF) and paraxanthine (PAX) kinetics after acute ingestion of caffeine (3 mg/kg body mass) in the form or mono- or multi-ingredient preparations and CrossFit®-specific…
- Conditions
- Supplementation, Sports Nutrition, Ergogenic Support, Discipline-specific Performance
- Trial name
- NCT05516212
- Testing
- CAFMONO supplementation, CAFMIPS_1 supplementation, CAFMIPS_2 supplementation
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Caffeine, Flavonoids
Effects of a Cocoa Shot on the Human Brain
The Hershey Company is interested in investigating the effects of various chocolate beverages on brain physiology and cognitive function.
- Trial name
- NCT01924481
- Testing
- High Caffeine, Low caffeine, High theobromine
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Drug Drug Interaction (DDI)
Drug-Drug Interaction (DDI) Study for TD-9855
This study is designed to assess the effect of fluvoxamine, itraconazole and smoking on the PK disposition of multiple doses TD-9855 in healthy male subjects.
- Trial name
- NCT03432793
- Testing
- TD-9855, Fluvoxamine, Itraconazole
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Bronchopulmonary Dysplasia, Apnea of Prematurity
Early Versus Late Caffeine for ELBW Newborns
Caffeine is routinely used in the management of apnea of prematurity. Extremely low birth weight (ELBW) infants are at higher risk of mortality and various neonatal morbidities such as bronchopulmonary dysplasia (BPD) for which…
- Trial name
- NCT02524249
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Healthy, Young Adults, Athletic Performance
Effects of an Acute Dose of Caffeine on the Performance of CrossFit Athletes
The goal of this clinical trial was to investigate the effect of an acute dose of caffeine on CrossFit performance in young, healthy male CrossFit athletes.
- Trial name
- NCT06891469
- Testing
- Caffeine administration according to body mass (moderate intake- 7 mg/kg)
- Where
- Greece
- Volunteers
- 12 people
- Sponsor
- Democritus University of Thrace
Healthy
Pre-workout Supplement Versus Caffeine on Energy Expenditure.
The primary purpose of this study was to examine the acute effects of a multi-ingredient pre-workout supplement versus an ergogenic dose of caffeine (6 mg/kg) on energy expenditure during low-intensity exercise.
- Trial name
- NCT04539054
- Testing
- ENGN Shred, Nutricost caffeine powder, Crystal Light
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northern Illinois University
Obesity
The Effect of Leptin A-200, Caffeine/Ephedrine and Their Combination Upon Weight Loss and Body Composition in Man
The purpose of this study is to compare three treatments to see which causes the most weight loss, fat loss, loss of stomach fat and improvement in blood tests like cholesterol.
- Trial name
- NCT01710722
- Testing
- caffeine and ephedrine, Leptin A, caffeine, ephedrine, and leptin A
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Muscle Power
Effects of Caffeine-based Supplement on Physical Performance
The aim of the study was to determine the acute effects of multi-ingredient pre-workout supple-ment (MIPS) containing: beta-alanine, taurine, caffeine, L-tyrosine, and cayenne pepper (capsaicin) on physical performance in…
- Trial name
- NCT06363669
- Testing
- multi-ingredient pre-workout dietary supplement (caffeine-based)
- Where
- Poland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland