Chronic PainERASEDNCT05991440
Examining Racial and Socioeconomic Differences in Chronic Low Back Pain
An observational study of Chronic Pain, run by Washington University School of Medicine at 1 site in United States.
Trial summary
The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP). Read more about this study
- Who is it for?
- Ages 18 to 85 years
- Conditions the study is for
- Chronic Pain
- How many people
- 240 participants
- Where
- 1 siteUnited States
- Study dates
- 22 Apr 2024to 31 Dec 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: For this study we will incorporate a combination of clinic-based and community-based participant recruitment. Participants will be recruited from the Pain Treatment Clinics at the Wash U Pain Center and VUMC, as well as the surrounding communities in St. Louis and Nashville, respectively.
Who may be able to join
- Non-specific cLBP that has persisted for at least 3 months and has resulted in pain on at least half the days in the past 6 months.
- Age 18 - 85; the lower end of this age range was chosen to capture the growing prevalence of young adults with cLBP, and participants over 85 years are increasingly likely to meet one or more exclusion criteria.
- Participants report ethnic group as non-Hispanic and racial group as either Black/African American or White/Caucasian.
Who cannot join
- Low back pain that is attributable to other factors such as ankylosing spondylitis, infection, malignancy, compression fracture of other trauma.
- Systemic rheumatic disease/condition (e.g. rheumatoid arthritis, systemic lupus erythematosus, fibromyalgia).
- Any other chronic pain condition that the participant believes to be more prominent or severe than the low back pain.
- A history of clinically significant surgery to the low back within the past year.
- Uncontrolled hypertension (i.e. SBP/DBP of > 150/95), cardiovascular or peripheral arterial disease.
- Poorly controlled diabetes (HbA1c > 8%).
Show all 9Show fewer
- Neurological disease (e.g. Parkinson's, multiple sclerosis, epilepsy).
- Serious psychiatric disorder requiring hospitalization within the past 12 months or characterized by active suicidal ideation.
- Diminished cognitive function that would interfere with understanding of study procedures.
Trial locations and contacts
1 site in 1 country.
United States1 site
Washington University School of Medicine
St Louis, Missouri, 63110
About this study
Official title: Racial and Socioeconomic Differences in Chronic Low Back Pain
The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP).
- Conditions
- Chronic Pain
- Keywords
- lower back pain, Race, Socioeconomic
- Medical subject headings
- Chronic Pain, Low Back Pain
What is being measured
The primary outcome is the main question the study is designed to answer.
To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP.
Clinical pain severity will be observed through quantitative sensory testing and self-reported questionnaires and surveys.
Measured: two years
To elucidate racial group disparities in experimental pain sensitivity among NHBs and NHWs with cLBP.
Quantitative sensory testing equipment and biological markers assayed via blood samples.
Measured: two years
To elucidate racial group disparities in psychosocial risk factors, among NHBs and NHWs with cLBP.
Psychosocial risk factors that will be observed will be greater increases in depressive symptoms, anxiety, and perceived stress, as well as greater social isolation and loneliness through the use of self-reported questionnaires and surveys.
Measured: two years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2023
- Study start22 Apr 2024
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic PainStudies of the same condition, open and under way.
- More trials run by Washington University School of MedicineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 240 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Washington University School of Medicine
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Minority Health and Health Disparities (NIMHD)
- Responsible party
- Principal investigator, Burel Goodin, Washington University School of Medicine
- Investigators
- Burel Goodin, PhD, Principal investigator, Washington University School of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05991440
- Sponsor's protocol ID
- 202306132
- Other IDs
- R01MD017565
- Acronym
- ERASED
- Status last verified
- Oct 2026
- First submitted
- 31 Jul 2023
- Last updated
- 16 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Racial and Socioeconomic Differences in Chronic Low Back Pain
- ClinicalTrials.gov ID
- NCT05991440
- Acronym / sponsor ID
- ERASED / 202306132
- Conditions
- Chronic Pain
- Keywords
- lower back pain, Race, Socioeconomic
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 240 participants (estimated)
- Lead sponsor
- Washington University School of MedicineUniversity, hospital or other
- Collaborators
- National Institute on Minority Health and Health Disparities (NIMHD)
- Study start
- 22 Apr 2024 (actual)
- Primary completion
- 31 Dec 2027 (estimated)
- Study completion
- 31 Dec 2028 (estimated)
- First posted
- 14 Aug 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP).
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- For this study we will incorporate a combination of clinic-based and community-based participant recruitment. Participants will be recruited from the Pain Treatment Clinics at the Wash U Pain Center and VUMC, as well as the surrounding communities in St. Louis and Nashville, respectively.
Key inclusion criteria (3 listed)
- Non-specific cLBP that has persisted for at least 3 months and has resulted in pain on at least half the days in the past 6 months.
- Age 18 - 85; the lower end of this age range was chosen to capture the growing prevalence of young adults with cLBP, and participants over 85 years are increasingly likely to meet one or more exclusion criteria.
- Participants report ethnic group as non-Hispanic and racial group as either Black/African American or White/Caucasian.
Key exclusion criteria (9 listed)
- Low back pain that is attributable to other factors such as ankylosing spondylitis, infection, malignancy, compression fracture of other trauma.
- Systemic rheumatic disease/condition (e.g. rheumatoid arthritis, systemic lupus erythematosus, fibromyalgia).
- Any other chronic pain condition that the participant believes to be more prominent or severe than the low back pain.
- A history of clinically significant surgery to the low back within the past year.
- Uncontrolled hypertension (i.e. SBP/DBP of > 150/95), cardiovascular or peripheral arterial disease.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP.
Time frame: two years
Clinical pain severity will be observed through quantitative sensory testing and self-reported questionnaires and surveys.
To elucidate racial group disparities in experimental pain sensitivity among NHBs and NHWs with cLBP.
Time frame: two years
Quantitative sensory testing equipment and biological markers assayed via blood samples.
To elucidate racial group disparities in psychosocial risk factors, among NHBs and NHWs with cLBP.
Time frame: two years
Psychosocial risk factors that will be observed will be greater increases in depressive symptoms, anxiety, and perceived stress, as well as greater social isolation and loneliness through the use of self-reported questionnaires and surveys.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Oct 2026.
Related trials for Chronic Pain
Recruiting
Empowered Relief® for Cancer Survivors With Chronic Pain
Chronic Pain Due to Cancer, Pain Catastrophizing
RecruitingObservational study
Pain Phenotypes in Individuals With Multiple Sclerosis
Multiple Sclerosis, Chronic Pain
Not yet recruiting
Effect of Lumbar Stabilization Exercises With and Without YTWL (Scapular Stabilization Exercises) on Reducing Chronic Low Back Pain and Related Disability. A Randomized Clinical Trial,
Chronic Non Specific Mechanical Low Back Pain
Not yet recruiting
Comparing Non-Medicine Strategies for Improving Low Back Pain
Chronic Low-back Pain (cLBP), High-Impact Chronic Pain (HICP)
Not yet recruiting
Effect of Pectoral Nerve Block (PECS) Using Magnesium Sulfate Added to Dexamethasone on Quality of Recovery and Chronic Post-Mastectomy Pain
Breast Cancer, Postoperative Pain
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Burel Goodin, PhD principal investigator
Washington University School of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Chronic Pain, run by Washington University School of Medicine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 16 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP. (time frame: two years). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Oct 2026.