Chronic Pain Due to CancerNCT07578376
Empowered Relief® for Cancer Survivors With Chronic Pain
A study testing Empowered Relief Course (Zoom) in people with Chronic Pain Due to Cancer and Pain Catastrophizing, run by University of Oklahoma at 1 site in United States.
Trial summary
This randomized controlled study to examine the efficacy of ER class in cancer survivors with chronic pain. Eligible participants will be randomly assigned to a ER class or a waitlist control condition. We will recruit 250 participants with a goal of having 200 completers (20% attrition). Read more about this study
- Who is it for?
- Ages 18 to 120 years
- Conditions the study is for
- Chronic Pain Due to Cancer, Pain Catastrophizing
- What is being tested?
- Empowered Relief Course (Zoom)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 215 participants
- Where
- 1 siteUnited States
- Study dates
- Jan 2027to 30 Apr 2030
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 120 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- History of cancer diagnosis, completion of active cancer treatment, cancer free at the time of enrollment, experience of body pain most or every day, pain duration at least 3 months, and English fluency.
Who cannot join
- Significant psychological and cognitive impairment that limits one's ability to complete study tasks (completion of online survey, attending the zoom-based ER class). Life-threatening acute illness (e.g., infection, heart attack, injury), and no access to a computer, a smartphone or a tablet.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Jordan Keast, BS contact
United States1 site, 1 recruiting
- Recruiting
University of Oklahoma Schusterman Center - Tulsa
Tulsa, Oklahoma, 74135
Jordan Keast, BS, jordan-keast@ou.edu
About this study
Official title: Feasibility and Preliminary Efficacy of Empowered Relief® for Cancer Survivors With Chronic Pain
This randomized controlled study to examine the efficacy of ER class in cancer survivors with chronic pain. Eligible participants will be randomly assigned to a ER class or a waitlist control condition. We will recruit 250 participants with a goal of having 200 completers (20% attrition). Participants in the control condition will be invited to attend ER class after the 3-month observation period.
Read the detailed description
The Empowered Relief (ER) study is a Zoom-based, 1-session, 2-hour, skills-based pain management class delivered by certified instructors. Participants learn three core pain relief skills, develop a personalized plan, and receive access to a free binaural audio app for daily use and supportive daily text messages. Participants will fill out a series of follow-up surveys at the 1, 2, and 3-month post-class mark. These surveys will be directly compared to surveys given to participants that do not complete the course. Class admittance will be randomized, however, participants not in the treatment group will have the option to take the course after the 3-month observatory period. ER has demonstrated moderate efficacy in individuals with chronic non-cancer pain, reducing pain intensity, pain interference, pain-related distress (pain catastrophizing), sleep disturbance, and anxiety. Because of its brief, didactic nature and delivery via Zoom, ER can accommodate large class sizes and may address access disparities among underserved cancer survivors. ER is currently being studied across various non-cancer populations and has been adopted as standard of care in leading healthcare institutions in the U.S. and abroad. Yet, Empowered Relief has not been tested in cancer survivors.
- Conditions
- Chronic Pain Due to Cancer, Pain Catastrophizing
- Being tested
- Empowered Relief Course (Zoom)
- Keywords
- Empowered Relief, Chronic Pain, Cancer survivor, Survey Study, Monthly follow-ups, Zoom class
- Medical subject headings
- Chronic Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Empowered Relief Course (Zoom)Behavioural
This is a one-time 2 hour long skills-based pain management class delivered by certified instructors. Participants learn three core pain relief skills, develop a personalized plan, and receive access to a free binaural audio app for daily use and supportive daily text messages.
| Study group | Role | What they receive |
|---|---|---|
| Empowered Relief | Experimental | Participants in this arm of the study will complete the one-time 2hr Empowered Relief zoom course. They will also complete a post-course survey as well as the standardized 1, 2, and 3-month follow-up surveys. Receives: Behavioral: Empowered Relief Course (Zoom) |
| Wait-List Control | No intervention | Participants in the Wait-List Control (WLC) arm will not have initial access to the empowered relief course. Additionally they will not have to complete a post-course survey. The WLC group will be asked to complete the 1, 2, and 3-month follow-up studies after no intervention. After this 3-month observatory period, WLC participants will have voluntary access to the Empowered Relief course. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Overall treatment satisfaction
0-10 scale, higher scores indicate greater satisfaction, mean should be 8 or higher
Measured: Immediately after intervention
Secondary outcomes (4)
Pain Intensity
0-10 scale, higher scores indicate higher pain
Measured: 1 month after intervention
Pain Interference
T-scores, higher scores indicate higher pain interference
Measured: 1 month after intervention
Pain Intensity
0-10 Scale, higher scores indicate higher pain
Measured: 3 months after intervention
Pain Interference
T-scores, higher scores indicate higher pain interference
Measured: 3 months after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study startJan 2027 (estimated)
- Primary completion31 Dec 2029 (estimated)
- Study completion30 Apr 2030 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Pain Due to CancerStudies of the same condition, open and under way.
- More trials run by University of OklahomaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 215 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Oklahoma
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Sophia You, PhD, ABPP, Principal investigator, University of Oklahoma
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07578376
- Sponsor's protocol ID
- 18957P
- Status last verified
- Nov 2026
- First submitted
- 28 Apr 2026
- Last updated
- 6 Nov 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Feasibility and Preliminary Efficacy of Empowered Relief® for Cancer Survivors With Chronic Pain
- ClinicalTrials.gov ID
- NCT07578376
- Acronym / sponsor ID
- 18957P
- Conditions
- Chronic Pain Due to Cancer, Pain Catastrophizing
- Keywords
- Empowered Relief, Chronic Pain, Cancer survivor, Survey Study, Monthly follow-ups, Zoom class
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 215 participants (estimated)
- Lead sponsor
- University of OklahomaUniversity, hospital or other
- Study start
- Jan 2027 (estimated)
- Primary completion
- 31 Dec 2029 (estimated)
- Study completion
- 30 Apr 2030 (estimated)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled study to examine the efficacy of ER class in cancer survivors with chronic pain. Eligible participants will be randomly assigned to a ER class or a waitlist control condition. We will recruit 250 participants with a goal of having 200 completers (20% attrition). Participants in the control condition will be invited to attend ER class after the 3-month observation period.
Detailed description
The Empowered Relief (ER) study is a Zoom-based, 1-session, 2-hour, skills-based pain management class delivered by certified instructors. Participants learn three core pain relief skills, develop a personalized plan, and receive access to a free binaural audio app for daily use and supportive daily text messages. Participants will fill out a series of follow-up surveys at the 1, 2, and 3-month post-class mark. These surveys will be directly compared to surveys given to participants that do not complete the course. Class admittance will be randomized, however, participants not in the treatment group will have the option to take the course after the 3-month observatory period. ER has demonstrated moderate efficacy in individuals with chronic non-cancer pain, reducing pain intensity, pain interference, pain-related distress (pain catastrophizing), sleep disturbance, and anxiety. Because of its brief, didactic nature and delivery via Zoom, ER can accommodate large class sizes and may address access disparities among underserved cancer survivors. ER is currently being studied across various non-cancer populations and has been adopted as standard of care in leading healthcare institutions in the U.S. and abroad. Yet, Empowered Relief has not been tested in cancer survivors.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Empowered Relief | Experimental | Behavioral: Empowered Relief Course (Zoom)Participants in this arm of the study will complete the one-time 2hr Empowered Relief zoom course. They will also complete a post-course survey as well as the standardized 1, 2, and 3-month follow-up surveys. |
| Wait-List Control | No intervention | –Participants in the Wait-List Control (WLC) arm will not have initial access to the empowered relief course. Additionally they will not have to complete a post-course survey. The WLC group will be asked to complete the 1, 2, and 3-month follow-up studies after no intervention. After this 3-month observatory period, WLC participants will have voluntary access to the Empowered Relief course. |
Who may qualify
- Ages
- 18 to 120 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- History of cancer diagnosis, completion of active cancer treatment, cancer free at the time of enrollment, experience of body pain most or every day, pain duration at least 3 months, and English fluency.
Key exclusion criteria (1 listed)
- Significant psychological and cognitive impairment that limits one's ability to complete study tasks (completion of online survey, attending the zoom-based ER class). Life-threatening acute illness (e.g., infection, heart attack, injury), and no access to a computer, a smartphone or a tablet.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Empowered Relief Course (Zoom)This is a one-time 2 hour long skills-based pain management class delivered by certified instructors. Participants learn three core pain relief skills, develop a personalized plan, and receive access to a free binaural audio app for daily use and supportive daily text messages. | Behavioural | Empowered Relief |
Primary outcome
Overall treatment satisfaction
Time frame: Immediately after intervention
0-10 scale, higher scores indicate greater satisfaction, mean should be 8 or higher
4 secondary outcomes
Pain Intensity
Time frame: 1 month after intervention
Pain Interference
Time frame: 1 month after intervention
Pain Intensity
Time frame: 3 months after intervention
Pain Interference
Time frame: 3 months after intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Nov 2026.
- Individual participant dataSharing planned: No
Related trials for Chronic Pain Due to Cancer
Recruiting
Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
Erectile Dysfunction Due to Arterial Insufficiency, Erectile Dysfunction
Not yet recruitingPhase 1
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
Chronic Insomnia, Sleep Deprivation
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Jordan Keast, BS contact
Sophia You, PhD, ABPP principal investigator
University of Oklahoma
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Empowered Relief Course (Zoom) in people with Chronic Pain Due to Cancer and Pain Catastrophizing, run by University of Oklahoma at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 6 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sophia You, PhD, ABPP (918-660-3923, Dokyoung-You@ou.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Overall treatment satisfaction (time frame: Immediately after intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Nov 2026.