Heart FailureNCT06076447
Urdu Translation and Validation of MLHFQ
An observational study of Heart Failure, run by Riphah International University at 1 site in Pakistan.
Trial summary
To translate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) questionnaire into Urdu language of Pakistan. To determine the validity and reliability of cross cultural adapted and Urdu translated MLHFQ questionnaire version among HF patients. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Heart Failure
- How many people
- 210 participants
- Where
- 1 sitePakistan
- Study dates
- 12 Nov 2023to 30 Dec 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Heart Failure individuals
Who may be able to join
- Patients with chronic heart failure who sought treatment at the outpatient cardiology clinic.
- Who could read and write in Urdu and English language and are willing to participate in the study.
Who cannot join
- Decline consent
- Communication barriers or cognitive disorder as well as those with exacerbated condition and those who were not available for re-test were excluded from the study.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Cross-Cultural Adaptation and Validation of the Urdu Version of the Minnesota Living With Heart Failure Questionnaire (MLHFQ) Among Individuals With Heart Failure
- To translate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) questionnaire into Urdu language of Pakistan.
- To determine the validity and reliability of cross cultural adapted and Urdu translated MLHFQ questionnaire version among HF patients.
- Conditions
- Heart Failure
- Medical subject headings
- Heart Failure
What is being measured
The primary outcome is the main question the study is designed to answer.
Quality of life (Minnesota Living with Heart Failure Questionnaire)
Quality of life will be measured through Minnesota Living with Heart Failure Questionnaire (MLHFQ). It is one of the most widely used health-related quality of life questionnaires for individuals with HF. It provides scores for two dimensions, physical and emotional, and a total score. The MLHFQ is a self-administered, 21-item disease-specific instrument for individuals with HF. Each item is scored in a 6-point Likert Scale (0 to 5), thus the total score could range from 0 to 105, with higher scores indicating more significant impairment in health-related quality of life. The MLHFQ has two domains; physical domain (eight items, score range from 0 to 40) and emotional domain (five items, score range from 0 to 25).
Measured: 6 months
Secondary outcomes (2)
Reliability of translated versions of Minnesota Living with Heart Failure Questionnaire
To determine reliability of MLHFQ in (URDU) language. Reliability refers to ability of a measure to produce same results administered at two or more intervals. Thus this will be test through test retest reliability
Measured: 6 months
Validity of translated versions of Minnesota Living with Heart Failure Questionnaire
To determine the validity of translation of MLHFQ. in (URDU) language. Validity is defined as how accurate the results are. Thus this will be measured through various parameters
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Oct 2023
- Study start12 Nov 2023
- Primary completion30 Dec 2025
- Study completion30 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Heart FailureStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 210 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Muhammad Iqbal Tariq, PhD*, Principal investigator, Riphah International UniversityArshad Nawaz Malik, PhD, Study chair, Riphah International UniversityShane Patman, PhD, Study chair, University of Notre Dame Australia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06076447
- Sponsor's protocol ID
- REC/PhD/01199 Iqbal Project B
- Status last verified
- Mar 2026
- First submitted
- 4 Oct 2023
- Last updated
- 19 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Cross-Cultural Adaptation and Validation of the Urdu Version of the Minnesota Living With Heart Failure Questionnaire (MLHFQ) Among Individuals With Heart Failure
- ClinicalTrials.gov ID
- NCT06076447
- Acronym / sponsor ID
- REC/PhD/01199 Iqbal Project B
- Conditions
- Heart Failure
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 210 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 12 Nov 2023 (actual)
- Primary completion
- 30 Dec 2025 (actual)
- Study completion
- 30 Dec 2025 (actual)
- First posted
- 10 Oct 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
- To translate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) questionnaire into Urdu language of Pakistan.
- To determine the validity and reliability of cross cultural adapted and Urdu translated MLHFQ questionnaire version among HF patients.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Heart Failure individuals
Key inclusion criteria (2 listed)
- Patients with chronic heart failure who sought treatment at the outpatient cardiology clinic.
- Who could read and write in Urdu and English language and are willing to participate in the study.
Key exclusion criteria (2 listed)
- Decline consent
- Communication barriers or cognitive disorder as well as those with exacerbated condition and those who were not available for re-test were excluded from the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Quality of life (Minnesota Living with Heart Failure Questionnaire)
Time frame: 6 months
Quality of life will be measured through Minnesota Living with Heart Failure Questionnaire (MLHFQ). It is one of the most widely used health-related quality of life questionnaires for individuals with HF. It provides scores for two dimensions, physical and emotional, and a total score. The MLHFQ is a self-administered, 21-item disease-specific instrument for individuals with HF. Each item is scored in a 6-point Likert Scale (0 to 5), thus the total score could range from 0 to 105, with higher scores indicating more significant impairment in health-related quality of life. The MLHFQ has two domains; physical domain (eight items, score range from 0 to 40) and emotional domain (five items, score range from 0 to 25).
2 secondary outcomes
Reliability of translated versions of Minnesota Living with Heart Failure Questionnaire
Time frame: 6 months
Validity of translated versions of Minnesota Living with Heart Failure Questionnaire
Time frame: 6 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Muhammad Iqbal Tariq, PhD* principal investigator
Riphah International University
Arshad Nawaz Malik, PhD study chair
Riphah International University
Shane Patman, PhD study chair
University of Notre Dame Australia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Heart Failure, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Quality of life (Minnesota Living with Heart Failure Questionnaire) (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Mar 2026; AzTrials last refreshed its copy on 6 Nov 2026.