Resistance TrainingNCT06078358
Resistance Exercise Training in Children.
A study testing Resistance exercise training in people with Resistance Training, run by University of Kansas Medical Center at 4 sites in United States.
Trial summary
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength, activation, and lipids of the vastus lateralis. Read more about this study
- Who is it for?
- Ages 8 to 10 yearsHealthy volunteers can take part
- Conditions the study is for
- Resistance Training
- What is being tested?
- Resistance exercise training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 4 sitesUnited States
- Study dates
- 2 Aug 2021to 6 Sep 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 8 to 10 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- Healthy volunteer males and females ages 8 - 10 years.
Who cannot join
- No history or ongoing neuromuscular diseases, musculoskeletal injuries, or a disease that effects metabolism.
Trial locations and contacts
4 sites in 1 country.
United States4 sites
Hoglund Biomedical Imaging Center
Kansas City, Kansas, 66103
Energy Balance Laboratory
Kansas City, Missouri, 64108
Exercise and Human Performance Laboratory
Overland Park, Kansas, 66213
Metabolic and Body Composition Laboratory
Overland Park, Kansas, 66213
About this study
Official title: The Effects of Resistance Exercise on Muscle Activation and Lipids in Children
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength, activation, and lipids of the vastus lateralis.
- Conditions
- Resistance Training
- Being tested
- Resistance exercise training
- Keywords
- exercise, muscle cross-sectional area, intramyocellular lipids, extramyocellular lipids, strength
- Medical subject headings
- Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Resistance exercise trainingOther
Traditional linear periodization resistance training.
| Study group | Role | What they receive |
|---|---|---|
| Resistance exercise training | Experimental | Participants undergo 8 weeks (3 days/week) of resistance exercise training. Receives: Other: Resistance exercise training |
| Control | No intervention | Participants do not perform 8 weeks of resistance exercise training. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in the muscular strength of leg extensors, as measured with isometric strength.
The score will reflect the strength of the leg extensors. The higher score, reflects greater muscular strength.
Measured: baseline, following the intervention (9 weeks)
Secondary outcomes (3)
Change from baseline in motor unit firing rates during a 60% of maximal voluntary contraction (MVC).
Scores are measured with the y-intercept from the firing rates versus recruitment threshold relationships from the 60%. The higher y-intercept score reflects greater muscle activation.
Measured: baseline, following the intervention (9 weeks)
Change from baseline in motor unit firing rates during a 60% of maximal voluntary contraction (MVC).
Scores are measured with the slope from the firing rates versus recruitment threshold relationships from the 60%. The higher slope score reflects greater muscle activation.
Measured: baseline, following the intervention (9 weeks)
Change from baseline in thigh muscle cross-sectional area.
Scores are measured cross-sectional area from ultrasound images.
Measured: baseline, following the intervention (9 weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Oct 2023
- Study start2 Aug 2021
- Primary completion6 Sep 2023
- Study completion6 Sep 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Resistance TrainingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 32 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Kansas Medical Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Strength and Conditioning Association
- Responsible party
- Principal investigator, Trent J. Herda, Ph.D., University of Kansas Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06078358
- Sponsor's protocol ID
- STUDY00147248
- Status last verified
- Oct 2023
- First submitted
- 5 Oct 2023
- Last updated
- 13 Oct 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 13 Oct 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Resistance Exercise on Muscle Activation and Lipids in Children
- ClinicalTrials.gov ID
- NCT06078358
- Acronym / sponsor ID
- STUDY00147248
- Conditions
- Resistance Training
- Keywords
- exercise, muscle cross-sectional area, intramyocellular lipids, extramyocellular lipids, strength
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 32 participants (actual)
- Lead sponsor
- University of Kansas Medical CenterUniversity, hospital or other
- Collaborators
- National Strength and Conditioning Association
- Study start
- 2 Aug 2021 (actual)
- Primary completion
- 6 Sep 2023 (actual)
- Study completion
- 6 Sep 2023 (actual)
- First posted
- 11 Oct 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength, activation, and lipids of the vastus lateralis.
Study design
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Resistance exercise training | Experimental | Other: Resistance exercise trainingParticipants undergo 8 weeks (3 days/week) of resistance exercise training. |
| Control | No intervention | –Participants do not perform 8 weeks of resistance exercise training. |
Who may qualify
- Ages
- 8 to 10 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (1 listed)
- Healthy volunteer males and females ages 8 - 10 years.
Key exclusion criteria (1 listed)
- No history or ongoing neuromuscular diseases, musculoskeletal injuries, or a disease that effects metabolism.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Resistance exercise trainingTraditional linear periodization resistance training. | Other | Resistance exercise training |
Primary outcome
Change in the muscular strength of leg extensors, as measured with isometric strength.
Time frame: baseline, following the intervention (9 weeks)
The score will reflect the strength of the leg extensors. The higher score, reflects greater muscular strength.
3 secondary outcomes
Change from baseline in motor unit firing rates during a 60% of maximal voluntary contraction (MVC).
Time frame: baseline, following the intervention (9 weeks)
Change from baseline in motor unit firing rates during a 60% of maximal voluntary contraction (MVC).
Time frame: baseline, following the intervention (9 weeks)
Change from baseline in thigh muscle cross-sectional area.
Time frame: baseline, following the intervention (9 weeks)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Oct 2023.
- Individual participant dataSharing planned: Yes
Related trials for Resistance Training
Not yet recruiting
Combined Versus Multicomponent Training in People With Chronic Kidney Disease Stages 3a and 3b
Chronic Kidney Disease Stage 3A, Chronic Kidney Disease Stage 3B
Not yet recruiting
Comparison Between Eccentric Hamstring Training and Sprint-Specific Training
Healthy Adult, Athlete
Not yet recruiting
Multicomponent Exercise and Pain Science Education for Fall Prevention in Older Adults With Chronic Musculoskeletal Pain (MovePainFall)
Chronic Pain, Musculoskeletal Pain
Not yet recruiting
Testing a Smartphone App to Support a Mediterranean Diet and Strength Exercise
Treatment Adherence and Compliance, Resistance Exercise
Recruiting
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
Colorectal Cancer, Colorectal Neoplasms
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
4 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Resistance exercise training in people with Resistance Training, run by University of Kansas Medical Center at 4 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Oct 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in the muscular strength of leg extensors, as measured with isometric strength. (time frame: baseline, following the intervention (9 weeks)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Oct 2023.