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EmergenciesTACCNCT06079099

Time Within the Acute Care Chain: How Long Have Medical Emergency Department Patients Spent

An observational study of Emergencies, run by Maastricht University Medical Center at 6 sites in Netherlands.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study is part of a research domain focusing on the acute care chain, which includes the patient journey from symptoms to treatment on the Emergency Medical Department (ED). Within hospitals there is much attention for triage and the amount of time patients spent within the chain, especially for the ED. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Emergencies
How many people
583 participants
Where
6 sitesNetherlands
Study dates
20 Apr 2022to 30 Aug 2022
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • Adult, Older adult

Study population: Adult patients who visit the ED in need of acute care

Who may be able to join

  • Patients of 18 years and older
  • Patient is treated at ED during inclusion period
  • Patient is able and willing to sign informed consent or has a legal representative

Who cannot join

  • Language barrier

Trial locations and contacts

6 sites in 1 country.

6 sites in 1 country

Netherlands6 sites
  • Zuyderland MC

    Heerlen

  • MUMC

    Maastricht, Limburg, 6202 AZ

  • Laurentius Ziekenhuis Roermond

    Roermond

  • Zuyderland MC

    Sittard

  • VieCuri

    Venlo

  • St. Jans Gasthuis Weert

    Weert

Other trials in Netherlands

About this study

This study is part of a research domain focusing on the acute care chain, which includes the patient journey from symptoms to treatment on the Emergency Medical Department (ED). Within hospitals there is much attention for triage and the amount of time patients spent within the chain, especially for the ED. However, there is less information available on what occurs before patients visit the ED. Gaining more insight in the patient journey in the acute care chain as a whole, might provide important information to further optimize care at the ED. In the current study, 750 patients will be included at multiple ED's in the Netherlands. The primary goal is to gain insight in the patient journey of adult ED patients.

Read the detailed description

All adult ED patients in the province of Limburg will be included in a 72 hour time frame. Students were present at the EDs 24 hours to include all these patients. Patient data were gathered from medical records (including hospital file, referral letters and EMS notes) using a Case Report Form (CRF) and from a questionnaire filled out by the patient. Data were collected on demographic variables, including sex, age, highest level of education, living situation and the presence of roommates. Furthermore, information regarding the ACC and Time spent in the ACC (TACC) was collected.

The entire ACC was divided into four phases: the pre-referral phase, the referral phase, the ED phase and the post ED phase. In each phase several variables were collected.

Pre-referral phase The pre-referral phase started with the onset of complaints this disease period up to the referring contact. The following variables of this phase were collected: the symptom duration in days calculated from the day of onset of symptoms until ED visit, number of prior contacts with a healthcare provider and prescribed medication this disease period before ED visit. A prior contact with a healthcare provider was defined as a contact within this disease period, regarding the same complaint, and before the contact during which the patient was referred to the ED.

Referral phase The referral phase started with the moment of referral until arrival at the ED. The following variables of this phase were collected: time and date of referral contact, referring health care provider (GP, EMS, medical specialist, nursing home doctor, other or self-referral), prehospital triage urgency (EMS and GCP), and mode of transportation to the ED (own transport or by EMS). Prehospital triage urgency levels (for GPC and EMS) are determined using the Netherlands Triage Standard (NTS), which categorizes patients from U1 (life threatening, immediate action required) up to U5 (advice, a physical examination can wait until the next day) (16). If necessary, an ambulance is subsequently dispatched according to these urgency levels.

ED phase The ED phase started with arrival at the ED until hospital discharge, including 30-day follow-up. The following variables of this phase were collected at the ED: referred specialty (the specialty to which the patient has been referred), treating specialty (the specialty that eventually treated/discharged/admitted the patient), triage urgency level (MTS (17)), presenting symptoms, the number of patients with a presumptive prespecified complex condition, ED work up, and arrival and departure time in the ED to calculate the length of stay (LOS).

The EDs in this study use the Manchester Triage System (MTS) as a triage system, which categorises patients into five levels of urgency (17). Immediate (red) patients are to be evaluated immediately, whereas non-urgent (blue) patients are allowed to wait for 240 minutes prior to evaluation. In this study we combined red and orange triage urgencies as 'highly urgent' (evaluation within 10 minutes maximum), and yellow, green and blue as 'urgent' (evaluation within 60-240 minutes). Presenting symptoms were categorized into 18 groups after discussion with the researchers: minor trauma, abdominal pain, dyspnoea, general malaise, fever, extremity complaints (e.g. arthritis), neurological complaints, syncope/palpitations, skin symptoms, urological complaints, complaints after treatment, allergic reaction, hypertension, minor oncological complaints (e.g. rash), chest pain, ENT problem, intoxication, and other. Prespecified complex conditions were defined as patients presenting with the presumptive diagnosis of a stroke, myocardial infarction, aortic syndrome or major trauma.

The ED work up was defined as simple when ED work-up included lab tests, electrocardiogram and X-ray and was defined complex when included CT, ultrasound, lumbar puncture (LP), abdominal paracentesis, gastroscopy, MRI scan and consultations of other specialties.

Post ED phase The post ED phase started after ED discharge until 30-day follow-up. The following variables were collected: post-ED disposition, 7- and 30-day all-cause mortality and 30-day revisit. A combination of 7- and 30-day all-cause mortality and 30-day revisit were called adverse outcome.

Conditions
Emergencies
Keywords
Acute Care Chain, Emergency Department, Patient Journey
Medical subject headings
Emergencies

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Total time a patient spent in acute care chain.

    Patient journey in the acute care chain. From all included patients: We measure the duration in the Acute care chain: From the moment a patient has contact with the referring healthcare provider until ED discharge

    Measured: up to hours with a maximum of 48 hours.Time unit: hours.

Secondary outcomes (4)
  1. Number of contacts with a healthcare provider this disease period

    Did patients have contact with care provider(s) before visiting the ED? If yes, which type of care providers were they and what was the urgency level? We ask the included patients during the inclusion periode how many healthcare providers the contacted: From first contact with a healthcare provider this disease period until entering the ED. This disease period = start complaints

    Measured: Days, maximum 14 days. Time unit: days.

  2. How many investigations were done during the ED visit

    Which investigations are carried out: blood test, ultrasound, x-ray? Patients that present in the inclusion period, at the ED. During the ED visit of the patient we look at the amount and which ancillary investigations are done. Timeframe = ED stay. No change is measured.

    Measured: During ED stay, that means in a couple of hours. ED stays are no longer that > 1 day. time unit is hours.

  3. Number of participant that are admitted to the hospital.

    What happens after ED visit? How many patients will be admitted.

    Measured: 30 days after ED visit we check on how many patients are admitted. Time frame 30 days. Unit: number of participants.

  4. Number of participant that are deceased after 30 days. .

    What happens after ED visit? How many patients died

    Measured: 30 days after ED visit we check on how many patients are deceased. Time frame 30 days. Unit: number of participants.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted12 Oct 2023
  2. Study start20 Apr 2022
  3. Primary completion24 Apr 2022
  4. Study completion30 Aug 2022

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Other
Time perspective
Prospective
Enrolment
583 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06079099
Sponsor's protocol ID
TACC
Acronym
TACC
Status last verified
Dec 2021
First submitted
22 Dec 2021
Last updated
12 Oct 2023
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • Claassen L, Stassen PM, Boumans TJT, Barten DG, Kremers MNT, Hermans AME, Zelis N, Cals JWL, Latten GHP. Characteristics of Dutch ED patients and their journey through the acute care chain: A province-wide flash-mob study. PLoS One. 2025 Apr 3;20(4):e0318510. doi: 10.1371/journal.pone.0318510. eCollection 2025.

    PubMed 40179077

Questions about this trial

What is this clinical trial studying?

An observational study of Emergencies, run by Maastricht University Medical Center at 6 sites in Netherlands.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 12 Oct 2023. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 6 sites in Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Total time a patient spent in acute care chain. (time frame: up to hours with a maximum of 48 hours.Time unit: hours.). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06079099, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Oct 2023.

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