Physiological StressHSL-APNCT06084494
Validation of Heat Stress Limit Values for the Athletic Performance
A study testing analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature in people with Physiological Stress and Heat Stress, run by University of the Punjab at 1 site in Pakistan.
Trial summary
Three male and three female semi-professional athletes, ranging in age from 22 to 27, participated in a study that was done at Lund University in Sweden to examine their physiological responses. Read more about this study
- Who is it for?
- Ages 22 to 27 yearsHealthy volunteers can take part
- Conditions the study is for
- Physiological Stress, Heat Stress, Sports Injury
- What is being tested?
- analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 6 participants
- Where
- 1 sitePakistan
- Study dates
- 21 Oct 2012to 30 Dec 2013
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 22 to 27 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Semiprofessional aged 22-27 years of both genders.
- Body surface area between 1.5 to 2.5 m2
- Semiprofessional participating in regional competition level, receive monetary compensation for their sports participation, participating in sports activity in the last six year, and skill level.
- Semiprofessional demonstrating a higher level of skill and performance than recreational or amateur participants .
Who cannot join
- Subjects should not have any known heart disease or circulatory disorder.
- No known respiratory disease or heat allergy.
- No habitual smoker or drug user.
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Department of Public Health, University of the Punjab
Lahore, Punjab Province, 54500
About this study
Official title: An Experimental Investigation of Physiological Responses in Semiprofessional Athletes: Comparing the Impact of Climatic Conditions, Physical Activity, and Gender
Three male and three female semi-professional athletes, ranging in age from 22 to 27, participated in a study that was done at Lund University in Sweden to examine their physiological responses. The temperature and relative humidity were adjusted at 40 degrees Celsius for hot, dry conditions and 31 degrees Celsius for hot, wet conditions, respectively. The participants were instructed to engage in physical activity on a treadmill within the chamber for 70 minutes, or until participants were able to continue their exercise without difficulty within the allotted period. Participants were instructed to walk (5 kph) and run (8 kph). Participants pulse rate, breathing rate, oxygen consumption, and subjective reactions were all recorded.
On the basis of the Wet Bulb Globe Temperature (WBGT), a heat stress index, the American College of Sports Medicine has made certain suggestions. The technique used to determine the temperature on a Celsius scale took into account the influences of relative humidity, air temperature, wind, and direct sunlight radiation. The American College of Sports Medicine advises delaying athletic competition when the WBGT is above 28 degrees. In the climate control chamber, the trials were carried out in high-risk circumstances (28 degrees Celsius WBGT). According to the study's findings, exercise is influenced by weather, and as air temperature rises, so do the intensity of exertion and thermal feeling.
Read the detailed description
Methodology Experimental research design Study Duration 6 months Study Centres Thermal Environment Laboratory, Department of Design Sciences, Faculty of Engineering (LTH), Lund University Main Objectives Objective 1: To examine the physiological responses (skin temperature, core body temperature, body temperature, heart rate, and oxygen uptake) of semi-professional athletes during physical activity in different climatic conditions (hot wet and hot dry) Objective 2: To compare the effects of physical activity intensity (5 km/hr and 8 km/hr) on the physiological responses of semi-professional athletes under varying climatic conditions.
Objective 3: To investigate the influence of gender on the physiological responses of semi-professional athletes during physical activity in different climatic conditions.
Objective 4: To assess the suitability of the Physiological Heat Strain (PHS) and Wet Bulb Globe Temperature (WBGT) index for evaluating heat stress in sports settings based on the findings from semi-professional athletes.
No. of Participants Six semiprofessional athletes including three males and three females with a mean age of (24.7 ± 2.1 years) and a body surface area mean of (1.8 ± 0.2 m2) participated in this study.
Main Eligibility Criteria Key factors to consider when defining semiprofessionals include participation in regional competition level, receiving monetary compensation for their sports participation, participating in sports activity in the last six years, and skill level. These athletes typically demonstrate a higher level of skill and performance than recreational or amateur participants.
- Being tested
- analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature
- Keywords
- Heat Stress, Physiological Responses, WBGT, PHS
- Medical subject headings
- Heat Stress Disorders, Athletic Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe TemperatureDiagnostic test
The temperature inside the climatic chamber was set at 40 C and 31 C at a relative humidity of 20 % and 70 % respectively to count for a WBGT level of 28 C. The subject does walk at 5 km/h and jog at 8 km/h under these conditions for up to 70 minutes. The test includes the measurement of the height and weight of the subjects, heart rate, oxygen consumption, body weight loss (sweat evaporation), skin temperature, and core body temperature under hot environmental conditions. Subjective responses will also be recorded. WBGT was recorded after every ten minutes by heat stress meter and Bruel Kjaer.
| Study group | Role | What they receive |
|---|---|---|
| Test Condition 1 | Experimental | Variable Test Condition 1 WBGT 28 °C Clothing High Visibility Air Temperature 40 °C RH % 20 % Vapor Pressure 2.3 kPa Walking Speed 5 km/h Time 70 min Receives: Diagnostic Test: analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature |
| Test Condition 2 | Experimental | Variable Test Condition 2 WBGT 28 °C Clothing High Visibility Air Temperature 40 °C RH % 20 % Vapor Pressure 2.3 kPa Walking Speed 8 km/h Time 70 min Receives: Diagnostic Test: analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature |
| Test Condition 3 | Experimental | Variable Test Condition 3 WBGT 28 °C Clothing High Visibility Air Temperature 31 °C RH % 70 % Vapor Pressure 3.1 kPa Walking Speed 5 km/h Time 70 min Receives: Diagnostic Test: analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature |
| Test Condition 4 | Experimental | Variable Test Condition 4 WBGT 28 °C Clothing High Visibility Air Temperature 31 °C RH % 70 % Vapor Pressure 3.1 kPa Walking Speed 8 km/h Time 70 min Receives: Diagnostic Test: analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature |
What is being measured
The primary outcome is the main question the study is designed to answer.
Physiological Response
Rate of change of skin temperature (Tsk) of semi-professional athletes during walking 5km/hr and Jogging 8km/hr for 70 minutes in hot wet (Ta 40 C \& 70% RH) and hot dry (Ta 31C \& 20% RH) test conditions.
Measured: 70 minutes
Physiological Response
Rate of change of core body temperature (Tcore) of semi-professional athletes during walking 5km/hr and Jogging 8km/hr for 70 minutes in hot wet (Ta 40 C \& 70% RH) and hot dry (Ta 31 C \& 20% RH) test conditions.
Measured: 70 minutes
Physiological Response
Rate of change of Heart Rate (HR bpm) of semi-professional athletes during walking 5km/hr and Jogging 8km/hr for 70 minutes in hot wet (Ta 40 C \& 70% RH) and hot dry (Ta 31 C \& 20% RH) test conditions.
Measured: 70 minutes
Physiological Response
Consumption of oxygen (VO2 Max ml/min/kg) of semi-professional athletes during walking 5km/hr and Jogging 8km/hr for 70 minutes in hot wet (Ta 40 C \& 70% RH) and hot dry (Ta 31 C \& 20% RH) test conditions.
Measured: 70 minutes
Secondary outcomes (2)
Gender-Based Physiological Responses
Gender-based comparison of the change in core body temperature of semi-professional athletes while performing various physical activities at 28 C WBGT
Measured: 70 minutes
Heat Stress Indices
Comparison of Physiological Heat Strain (PHS) and Wet Bulb Globe Temperature (WBGT) index for evaluating heat stress in sports settings based on the core body temperature responses from semi-professional athletes.
Measured: 70 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Oct 2023
- Study start21 Oct 2012
- Primary completion1 Feb 2013
- Study completion30 Dec 2013
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Physiological StressStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Factorial
- Model description
- A wet Bulb Globe temperature (WBGT) level of 28 °C was simulated, and the temperature within the climatic chamber was set at 40 °C and 31 °C at relative humidity levels of 20% and 70%, respectively. Four test conditions were designed and subjects ran at 8 km/h and walked at 5 km/h for up to 70 minutes.
- Masking
- None (open label)
- Enrolment
- 6 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of the Punjab
- Sponsor type
- University, hospital or other
- Collaborators
- Lund University
- Responsible party
- Principal investigator, Muhammad Salman Butt, University of the Punjab
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06084494
- Sponsor's protocol ID
- VEN 99 -11
- Acronym
- HSL-AP
- Status last verified
- Mar 2025
- First submitted
- 2 Aug 2023
- Last updated
- 30 Mar 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- An Experimental Investigation of Physiological Responses in Semiprofessional Athletes: Comparing the Impact of Climatic Conditions, Physical Activity, and Gender
- ClinicalTrials.gov ID
- NCT06084494
- Acronym / sponsor ID
- HSL-AP / VEN 99 -11
- Keywords
- Heat Stress, Physiological Responses, WBGT, PHS
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 6 participants (actual)
- Lead sponsor
- University of the PunjabUniversity, hospital or other
- Collaborators
- Lund University
- Study start
- 21 Oct 2012 (actual)
- Primary completion
- 1 Feb 2013 (actual)
- Study completion
- 30 Dec 2013 (actual)
- First posted
- 16 Oct 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Three male and three female semi-professional athletes, ranging in age from 22 to 27, participated in a study that was done at Lund University in Sweden to examine their physiological responses. The temperature and relative humidity were adjusted at 40 degrees Celsius for hot, dry conditions and 31 degrees Celsius for hot, wet conditions, respectively. The participants were instructed to engage in physical activity on a treadmill within the chamber for 70 minutes, or until participants were able to continue their exercise without difficulty within the allotted period. Participants were instructed to walk (5 kph) and run (8 kph). Participants pulse rate, breathing rate, oxygen consumption, and subjective reactions were all recorded.
On the basis of the Wet Bulb Globe Temperature (WBGT), a heat stress index, the American College of Sports Medicine has made certain suggestions. The technique used to determine the temperature on a Celsius scale took into account the influences of relative humidity, air temperature, wind, and direct sunlight radiation. The American College of Sports Medicine advises delaying athletic competition when the WBGT is above 28 degrees. In the climate control chamber, the trials were carried out in high-risk circumstances (28 degrees Celsius WBGT). According to the study's findings, exercise is influenced by weather, and as air temperature rises, so do the intensity of exertion and thermal feeling.
Detailed description
Methodology Experimental research design Study Duration 6 months Study Centres Thermal Environment Laboratory, Department of Design Sciences, Faculty of Engineering (LTH), Lund University Main Objectives Objective 1: To examine the physiological responses (skin temperature, core body temperature, body temperature, heart rate, and oxygen uptake) of semi-professional athletes during physical activity in different climatic conditions (hot wet and hot dry) Objective 2: To compare the effects of physical activity intensity (5 km/hr and 8 km/hr) on the physiological responses of semi-professional athletes under varying climatic conditions.
Objective 3: To investigate the influence of gender on the physiological responses of semi-professional athletes during physical activity in different climatic conditions.
Objective 4: To assess the suitability of the Physiological Heat Strain (PHS) and Wet Bulb Globe Temperature (WBGT) index for evaluating heat stress in sports settings based on the findings from semi-professional athletes.
No. of Participants Six semiprofessional athletes including three males and three females with a mean age of (24.7 ± 2.1 years) and a body surface area mean of (1.8 ± 0.2 m2) participated in this study.
Main Eligibility Criteria Key factors to consider when defining semiprofessionals include participation in regional competition level, receiving monetary compensation for their sports participation, participating in sports activity in the last six years, and skill level. These athletes typically demonstrate a higher level of skill and performance than recreational or amateur participants.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- None (open label)
- Number of arms
- 4
- Model description
- A wet Bulb Globe temperature (WBGT) level of 28 °C was simulated, and the temperature within the climatic chamber was set at 40 °C and 31 °C at relative humidity levels of 20% and 70%, respectively. Four test conditions were designed and subjects ran at 8 km/h and walked at 5 km/h for up to 70 minutes.
| Arm | Type | Receives |
|---|---|---|
| Test Condition 1 | Experimental | Diagnostic Test: analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe TemperatureVariable Test Condition 1 WBGT 28 °C Clothing High Visibility Air Temperature 40 °C RH % 20 % Vapor Pressure 2.3 kPa Walking Speed 5 km/h Time 70 min |
| Test Condition 2 | Experimental | Diagnostic Test: analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe TemperatureVariable Test Condition 2 WBGT 28 °C Clothing High Visibility Air Temperature 40 °C RH % 20 % Vapor Pressure 2.3 kPa Walking Speed 8 km/h Time 70 min |
| Test Condition 3 | Experimental | Diagnostic Test: analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe TemperatureVariable Test Condition 3 WBGT 28 °C Clothing High Visibility Air Temperature 31 °C RH % 70 % Vapor Pressure 3.1 kPa Walking Speed 5 km/h Time 70 min |
| Test Condition 4 | Experimental | Diagnostic Test: analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe TemperatureVariable Test Condition 4 WBGT 28 °C Clothing High Visibility Air Temperature 31 °C RH % 70 % Vapor Pressure 3.1 kPa Walking Speed 8 km/h Time 70 min |
Who may qualify
- Ages
- 22 to 27 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Semiprofessional aged 22-27 years of both genders.
- Body surface area between 1.5 to 2.5 m2
- Semiprofessional participating in regional competition level, receive monetary compensation for their sports participation, participating in sports activity in the last six year, and skill level.
- Semiprofessional demonstrating a higher level of skill and performance than recreational or amateur participants .
Key exclusion criteria (3 listed)
- Subjects should not have any known heart disease or circulatory disorder.
- No known respiratory disease or heat allergy.
- No habitual smoker or drug user.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe TemperatureThe temperature inside the climatic chamber was set at 40 C and 31 C at a relative humidity of 20 % and 70 % respectively to count for a WBGT level of 28 C. The subject does walk at 5 km/h and jog at 8 km/h under these conditions for up to 70 minutes. The test includes the measurement of the height and weight of the subjects, heart rate, oxygen consumption, body weight loss (sweat evaporation), skin temperature, and core body temperature under hot environmental conditions. Subjective responses will also be recorded. WBGT was recorded after every ten minutes by heat stress meter and Bruel Kjaer. | Diagnostic test | Test Condition 1, Test Condition 2, Test Condition 3, Test Condition 4 |
Primary outcome
Physiological Response
Time frame: 70 minutes
Rate of change of skin temperature (Tsk) of semi-professional athletes during walking 5km/hr and Jogging 8km/hr for 70 minutes in hot wet (Ta 40 C \& 70% RH) and hot dry (Ta 31C \& 20% RH) test conditions.
Physiological Response
Time frame: 70 minutes
Rate of change of core body temperature (Tcore) of semi-professional athletes during walking 5km/hr and Jogging 8km/hr for 70 minutes in hot wet (Ta 40 C \& 70% RH) and hot dry (Ta 31 C \& 20% RH) test conditions.
Physiological Response
Time frame: 70 minutes
Rate of change of Heart Rate (HR bpm) of semi-professional athletes during walking 5km/hr and Jogging 8km/hr for 70 minutes in hot wet (Ta 40 C \& 70% RH) and hot dry (Ta 31 C \& 20% RH) test conditions.
Physiological Response
Time frame: 70 minutes
Consumption of oxygen (VO2 Max ml/min/kg) of semi-professional athletes during walking 5km/hr and Jogging 8km/hr for 70 minutes in hot wet (Ta 40 C \& 70% RH) and hot dry (Ta 31 C \& 20% RH) test conditions.
2 secondary outcomes
Gender-Based Physiological Responses
Time frame: 70 minutes
Heat Stress Indices
Time frame: 70 minutes
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Mar 2025.
- Individual participant dataSharing planned: No
Related trials for Physiological Stress
Recruiting
Effect of a Brief Daily Digital Meditation on Well-Being in US Young Adults (BEGIN II)
Mental Health and General Well-being
Not yet recruiting
Hand in Hand: Feasibility of a Compassion-Focused App to Support Parents of Children With Mental Health Problems
Physiological Conditions, Distress, Emotional
Not yet recruiting
Eye Covering and White Noise During Nasogastric Tube Insertion in Preterm Infants
Preterm Infants
Recruiting
Effects of Moderate Exercise and Cyclic Sighing on Stress, Cognition and Physiological Markers in Young Adults
Stress
Not yet recruiting
Psychological and Physiological Effects of Three-Minute Breathing Space Meditation in UPM Postgraduate Students
Stress, Anxiety
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature in people with Physiological Stress and Heat Stress, run by University of the Punjab at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Physiological Response (time frame: 70 minutes). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Mar 2025.