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Muscle SorenessNCT06096389

Effect of Acheta Domesticus Supplementation on Post-Exercise Muscle Recovery in Recreationally Active Male

A study testing 100 Drop Jumps, Whey supplementation and Carbohydrate supplementation in people with Muscle Soreness, run by University of Malaya at 1 site in Malaysia.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The goal of this clinical trial is to test the effect of house cricket (Acheta domesticus) supplementation for strength recovery in recreationally active males. The main question[s] it aims to answer are: whether house cricket powder could improve strength recovery and whether house cricket powder could be an… Read more about this study

Who is it for?
Ages 18 to 30 years, men onlyHealthy volunteers can take part
Conditions the study is for
Muscle Soreness
What is being tested?
100 Drop Jumps, Whey supplementation and Carbohydrate supplementation
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
39 participants
Where
1 siteMalaysia
Study dates
1 Apr 2023to 31 Dec 2023
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 30 years
  • Men only
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • 5-10 hours of exercise per week

Who cannot join

  • smoking
  • drinking alcohol
  • history of surgical/medical procedure that could affect the study
  • food allergy
  • in medication
  • have participated in similar studies before

Trial locations and contacts

1 site in 1 country.

Malaysia1 site

  • Faculty of Sports and Exercise Sciences

    Kuala Lumpur, Kuala Lumpur, 59200

Other trials in Malaysia

About this study

The goal of this clinical trial is to test the effect of house cricket (Acheta domesticus) supplementation for strength recovery in recreationally active males. The main question[s] it aims to answer are: whether house cricket powder could improve strength recovery and whether house cricket powder could be an alternative to commonly used protein supplement. Participants will do exercise (100 drop jumps) to induce fatigue and then they will consume either isocaloric carbohydrate, whey protein isolate or defatted house cricket powder for 4 days. Their strength will be measured every 24 hours for 4 days in order to observe the recovery.

Researcher will compare house cricket powder with isocaloric carbohydrate to see if the strength recovery is faster in house cricket powder group

Researcher will compare house cricket powder with whey protein isolate to see if the strength recovery is comparable.

Read the detailed description

Participants: recreationally active males Study type: double-blind randomized controlled trial

Supplement dose is tailored to each participant daily protein consumption. It aims to reach 1.4 g/kg body weight protein, hence participant is required to provide dietary record 3 days before the experiment and during the experiment. Subject will attend one familiarization 1 week before the experiment. During day one of the experiment, subject warmed up before the session. Then their baseline strength and jumping measurement will be taken. Afterwards, they will do 20 reps of drop jumps for 5 sets (each set separated by 2 minutes rest). Immediately after the exercise, they will consume either whey, house cricket or maltodextrin. 10 minutes afterwards, they will undergo another strength and jumping measurement. 24, 48 and 72 hours after the exercise, subject will come for strength and jumping post-test after consuming the supplement. They are also required to fill in a visual analogue scale and 7-points Likert scale form regarding their pain and soreness perception.

Conditions
Muscle Soreness
Being tested
100 Drop Jumps, Whey supplementation, Carbohydrate supplementation, House cricket supplementation
Medical subject headings
Myalgia

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • 100 Drop JumpsOther

    100 drop jumps from 60 cm height. Divided into 5 sets of 20 reps

  • Whey supplementationDietary supplement

    Consume whey protein isolate based on subjects' daily protein intake

  • Carbohydrate supplementationDietary supplement

    Consume carbohydrate (isocaloric to whey)

  • House cricket supplementationDietary supplement

    Consume defatted house cricket powder based on subjects' daily protein intake

Study groups in NCT06096389
Study groupRoleWhat they receive
Maltodextrin (CHO)Placebo comparatorThis group will be given isocaloric carbohydrate (maltodextrin)
Receives: Other: 100 Drop Jumps; Dietary Supplement: Carbohydrate supplementation
Whey Protein Isolate (WIP)Active comparatorThis group will receive whey protein isolate
Receives: Other: 100 Drop Jumps; Dietary Supplement: Whey supplementation
House Cricket (HCP)ExperimentalThis group will receive house cricket powder
Receives: Other: 100 Drop Jumps; Dietary Supplement: House cricket supplementation

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Strength

    Isokinetic knee extension and flexion, maximum knee isometric contraction

    Measured: 72 hours

  2. Power

    Countermovement jump, squat jump

    Measured: 72 hours

  3. Pain Perception

    10 cm visual analogue scale (min 0 = no soreness, max 10 = worst imaginable muscle soreness) \& 7 Points Likert Scale (min 0 = no soreness, max 6 = a severe pain that limits my ability to move)

    Measured: 72 hours

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted23 Oct 2023
  2. Study start1 Apr 2023
  3. Primary completion30 Nov 2023
  4. Study completion31 Dec 2023

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Model description
Randomized, double-blind, controlled trial
Masking
Double blind
Who is masked
Participant, Investigator
Enrolment
39 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06096389
Sponsor's protocol ID
UM.TNC2/UMREC_2337
Status last verified
Mar 2025
First submitted
13 Oct 2023
Last updated
30 Mar 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Abaidia AE, Delecroix B, Leduc C, Lamblin J, McCall A, Baquet G, Dupont G. Effects of a Strength Training Session After an Exercise Inducing Muscle Damage on Recovery Kinetics. J Strength Cond Res. 2017 Jan;31(1):115-125. doi: 10.1519/JSC.0000000000001479.

    PubMed 27227793

  • Agriculture Organization of the United Nations, World Health Organization, & University, U. N. (2007). Protein and amino acid requirements in human nutrition : report of a joint FAO/WHO/UNU expert consultation. World Health Organization. https://apps.who.int/iris/handle/10665/43411

  • Awobusuyi TD, Pillay K, Siwela M. Consumer Acceptance of Biscuits Supplemented with a Sorghum-Insect Meal. Nutrients. 2020 Mar 25;12(4):895. doi: 10.3390/nu12040895.

    PubMed 32218250

  • Baiano A. (2020). Edible insects: an overview on nutritional characteristics, safety, farming, production technologies, regulatory framework, and socio-economic and ethical implications. Trends in Food Science & Technology. 100:35-50

  • Brogan, E. N., Park, Y. L., Matak, K. E., & Jaczynski, J. (2021). Characterization of protein in cricket (Acheta domesticus), locust (Locusta migratoria), and silk worm pupae (Bombyx mori) insect powders. Lwt-Food Science and Technology, 152, Article 112314. https://doi.org/10.1016/j.lwt.2021.112314

  • Brown MA, Stevenson EJ, Howatson G. Whey protein hydrolysate supplementation accelerates recovery from exercise-induced muscle damage in females. Appl Physiol Nutr Metab. 2018 Apr;43(4):324-330. doi: 10.1139/apnm-2017-0412. Epub 2017 Nov 6.

    PubMed 29106812

  • Borgenvik M, Apro W, Blomstrand E. Intake of branched-chain amino acids influences the levels of MAFbx mRNA and MuRF-1 total protein in resting and exercising human muscle. Am J Physiol Endocrinol Metab. 2012 Mar 1;302(5):E510-21. doi: 10.1152/ajpendo.00353.2011. Epub 2011 Nov 29.

    PubMed 22127230

  • Buckley JD, Thomson RL, Coates AM, Howe PR, DeNichilo MO, Rowney MK. Supplementation with a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise. J Sci Med Sport. 2010 Jan;13(1):178-81. doi: 10.1016/j.jsams.2008.06.007. Epub 2008 Sep 2.

    PubMed 18768358

  • Buford TW, Kreider RB, Stout JR, Greenwood M, Campbell B, Spano M, Ziegenfuss T, Lopez H, Landis J, Antonio J. International Society of Sports Nutrition position stand: creatine supplementation and exercise. J Int Soc Sports Nutr. 2007 Aug 30;4:6. doi: 10.1186/1550-2783-4-6. No abstract available.

    PubMed 17908288

  • Abbott W, Brett A, Cockburn E, Clifford T. Presleep Casein Protein Ingestion: Acceleration of Functional Recovery in Professional Soccer Players. Int J Sports Physiol Perform. 2019 Mar 1;14(3):385-391. doi: 10.1123/ijspp.2018-0385. Epub 2019 Feb 17.

    PubMed 30204517

  • Cooke MB, Rybalka E, Stathis CG, Cribb PJ, Hayes A. Whey protein isolate attenuates strength decline after eccentrically-induced muscle damage in healthy individuals. J Int Soc Sports Nutr. 2010 Sep 22;7:30. doi: 10.1186/1550-2783-7-30.

    PubMed 20860817

  • Cormack SJ, Newton RU, McGuigan MR, Doyle TL. Reliability of measures obtained during single and repeated countermovement jumps. Int J Sports Physiol Perform. 2008 Jun;3(2):131-44. doi: 10.1123/ijspp.3.2.131.

    PubMed 19208922

  • de Matos FM, Novelli PK, de Castro RJS. Enzymatic hydrolysis of black cricket (Gryllus assimilis) proteins positively affects their antioxidant properties. J Food Sci. 2021 Feb;86(2):571-578. doi: 10.1111/1750-3841.15576. Epub 2021 Jan 12.

    PubMed 33438276

  • Eddens L, Browne S, Stevenson EJ, Sanderson B, van Someren K, Howatson G. The efficacy of protein supplementation during recovery from muscle-damaging concurrent exercise. Appl Physiol Nutr Metab. 2017 Jul;42(7):716-724. doi: 10.1139/apnm-2016-0626. Epub 2017 Feb 15.

    PubMed 28199799

  • Etheridge T, Philp A, Watt PW. A single protein meal increases recovery of muscle function following an acute eccentric exercise bout. Appl Physiol Nutr Metab. 2008 Jun;33(3):483-8. doi: 10.1139/H08-028.

    PubMed 18461101

Questions about this trial

What is this clinical trial studying?

A study testing 100 Drop Jumps, Whey supplementation and Carbohydrate supplementation in people with Muscle Soreness, run by University of Malaya at 1 site in Malaysia.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 30 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Malaysia. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Strength (time frame: 72 hours). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06096389, which also lists 37 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Mar 2025.

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