Quality of LifeNCT06124911
Low-dose Maximal-intent Versus Controlled-tempo Resistance Training on Quality-of-life in Older Adults
A study testing Leg Press Resistance Training (3x5) and Leg Press Resistance Training (5x5) in people with Quality of Life, run by Northumbria University at 1 site in United Kingdom.
Trial summary
The aims of this study were to: 1. Compare the effects of low-dose Maximal Intent and Controlled Tempo Resistance Training on untrained healthy older adults' quality-of-life, functional capacity, and strength. 2. Read more about this study
- Who is it for?
- Ages 60 to 85 yearsHealthy volunteers can take part
- Conditions the study is for
- Quality of Life
- What is being tested?
- Leg Press Resistance Training (3x5) and Leg Press Resistance Training (5x5)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 38 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 30 May 2023to 5 Jun 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 to 85 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Participants were eligible if they were between 30-60 years old
- Uninjured
- Had no cardiovascular or neuromuscular conditions
- Had not participated in lower-limb resistance training in the previous six months.
Who cannot join
- Participants were excluded if they had either taken part in any lower-limb resistance training in the last six months
- Had underlying health condition(s) that prevented them from participating in resistance training
- Regularly met or exceeded the UK recommended physical activity guideline of 150-minutes of moderate to intense physical activity per week.
Trial locations and contacts
1 site in 1 country.
United Kingdom1 site
Northumbria University
Newcastle, Tyne and Wear, NE1 8ST
About this study
Official title: Comparison of Two Low-dose Resistance Training Modalities on Strength, Functional Capacity, and Quality-of-life in Healthy, Community-dwelling, Untrained Older Adults: a Randomised Controlled Trial
The aims of this study were to:
- Compare the effects of low-dose Maximal Intent and Controlled Tempo Resistance Training on untrained healthy older adults' quality-of-life, functional capacity, and strength.
- Qualitatively explore perceptions of Maximal Intent and Controlled Tempo Resistance Training in older adults.
Older adults are defined as being 60 or more years of age.
- Conditions
- Quality of Life
- Being tested
- Leg Press Resistance Training (3x5), Leg Press Resistance Training (5x5)
- Keywords
- Activities of Daily Living, Balance, Independence, Mobility, Untrained
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Leg Press Resistance Training (3x5)Other
Leg Press resistance training at 60% one-rep-max for three sets of five repetitions
Leg Press Resistance Training (5x5)Other
Leg Press resistance training at 60% one-rep-max for five sets of five repetitions
| Study group | Role | What they receive |
|---|---|---|
| Maximal-intent Resistance Training - 3x5 (MI3x5) | Experimental | The max-intent group were instructed and encouraged to deliberately commit to exerting maximal effort and force during the concentric phase of the leg press with the intention of achieving the greatest velocity possible. This group completed 3 sets of 5 repetitions at 60% one-repetition maximum. Receives: Other: Leg Press Resistance Training (3x5) |
| Maximal-intent Resistance Training - 5x5 (MI5x5) | Experimental | The max-intent group were instructed and encouraged to deliberately commit to exerting maximal effort and force during the concentric phase of the leg press with the intention of achieving the greatest velocity possible. This group completed 5 sets of 5 repetitions at 60% one-repetition maximum. Receives: Other: Leg Press Resistance Training (5x5) |
| Controlled-tempo Resistance Training - 3x5 (CT3x5) | Experimental | The controlled-tempo group followed a metronome for both eccentric and concentric phases of the leg press with the intention of maintaining a steady three-second concentric and three-second eccentric. This group completed 3 sets of 5 repetitions at 60% one-repetition maximum. Receives: Other: Leg Press Resistance Training (3x5) |
| Controlled-tempo Resistance Training - 5x5 (CT5x5) | Experimental | The controlled-tempo group followed a metronome for both eccentric and concentric phases of the leg press with the intention of maintaining a steady three-second concentric and three-second eccentric. This group completed 5 sets of 5 repetitions at 60% one-repetition maximum. Receives: Other: Leg Press Resistance Training (5x5) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Quality-of-life
Participant quality of life (measured through focus group questions \& SF-36)
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Secondary outcomes (8)
Balance
Using the biodex to do a 3 x 20s double-foot eyes-open balance test on Level 6.
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
6-minute Walk Test
A "brisk"-paced 6-minute walk test.
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Timed-up-and-go
Standing from a chair, walking to a point 3 metres away, turn, and return to the chair as quick as possible whilst walking.
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
30-second sit-to-stand (30s-Sit-to-Stand)
Maximal amount of repetitions a participant can stand up from a chair in 30-seconds.
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Strength
Participants one-repetition max on leg press machine.
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Body Mass Index
Mass and height will be combined to report BMI in kg/m^2
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Strength-to-mass Ratio
Mass and Leg Press 1RM will be combined to calculate strength-to-mass ratio.
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Leg press one-rep-max velocity pre-to-post
Velocity (m/s) of leg press measured at post-intervention, using baseline one-rep-max.
Measured: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Nov 2023
- Study start30 May 2023
- Primary completion5 Jun 2024
- Study completion5 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Quality of LifeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 38 participants (actual)
Sponsor and investigators
- Lead sponsor
- Northumbria University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06124911
- Sponsor's protocol ID
- NU2863
- Status last verified
- Nov 2023
- First submitted
- 29 Oct 2023
- Last updated
- 23 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Pearson LT, Behm DG, Goodall S, Mason R, Stuart S, Barry G. Effects of maximal-versus submaximal-intent resistance training on functional capacity and strength in community-dwelling older adults: a systematic review and meta-analysis. BMC Sports Sci Med Rehabil. 2022 Jul 16;14(1):129. doi: 10.1186/s13102-022-00526-x.
PubMed 35842655
Study at a glance
From the registry record, last updated by the sponsor on 23 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Two Low-dose Resistance Training Modalities on Strength, Functional Capacity, and Quality-of-life in Healthy, Community-dwelling, Untrained Older Adults: a Randomised Controlled Trial
- ClinicalTrials.gov ID
- NCT06124911
- Acronym / sponsor ID
- NU2863
- Conditions
- Quality of Life
- Keywords
- Activities of Daily Living, Balance, Independence, Mobility, Untrained
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 38 participants (actual)
- Lead sponsor
- Northumbria UniversityUniversity, hospital or other
- Study start
- 30 May 2023 (actual)
- Primary completion
- 5 Jun 2024 (actual)
- Study completion
- 5 Jun 2024 (actual)
- First posted
- 9 Nov 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aims of this study were to:
- Compare the effects of low-dose Maximal Intent and Controlled Tempo Resistance Training on untrained healthy older adults' quality-of-life, functional capacity, and strength.
- Qualitatively explore perceptions of Maximal Intent and Controlled Tempo Resistance Training in older adults.
Older adults are defined as being 60 or more years of age.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Maximal-intent Resistance Training - 3x5 (MI3x5) | Experimental | Other: Leg Press Resistance Training (3x5)The max-intent group were instructed and encouraged to deliberately commit to exerting maximal effort and force during the concentric phase of the leg press with the intention of achieving the greatest velocity possible. This group completed 3 sets of 5 repetitions at 60% one-repetition maximum. |
| Maximal-intent Resistance Training - 5x5 (MI5x5) | Experimental | Other: Leg Press Resistance Training (5x5)The max-intent group were instructed and encouraged to deliberately commit to exerting maximal effort and force during the concentric phase of the leg press with the intention of achieving the greatest velocity possible. This group completed 5 sets of 5 repetitions at 60% one-repetition maximum. |
| Controlled-tempo Resistance Training - 3x5 (CT3x5) | Experimental | Other: Leg Press Resistance Training (3x5)The controlled-tempo group followed a metronome for both eccentric and concentric phases of the leg press with the intention of maintaining a steady three-second concentric and three-second eccentric. This group completed 3 sets of 5 repetitions at 60% one-repetition maximum. |
| Controlled-tempo Resistance Training - 5x5 (CT5x5) | Experimental | Other: Leg Press Resistance Training (5x5)The controlled-tempo group followed a metronome for both eccentric and concentric phases of the leg press with the intention of maintaining a steady three-second concentric and three-second eccentric. This group completed 5 sets of 5 repetitions at 60% one-repetition maximum. |
Who may qualify
- Ages
- 60 to 85 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Participants were eligible if they were between 30-60 years old
- Uninjured
- Had no cardiovascular or neuromuscular conditions
- Had not participated in lower-limb resistance training in the previous six months.
Key exclusion criteria (3 listed)
- Participants were excluded if they had either taken part in any lower-limb resistance training in the last six months
- Had underlying health condition(s) that prevented them from participating in resistance training
- Regularly met or exceeded the UK recommended physical activity guideline of 150-minutes of moderate to intense physical activity per week.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Leg Press Resistance Training (3x5)Leg Press resistance training at 60% one-rep-max for three sets of five repetitions | Other | Controlled-tempo Resistance Training - 3x5 (CT3x5), Maximal-intent Resistance Training - 3x5 (MI3x5) |
| Leg Press Resistance Training (5x5)Leg Press resistance training at 60% one-rep-max for five sets of five repetitions | Other | Controlled-tempo Resistance Training - 5x5 (CT5x5), Maximal-intent Resistance Training - 5x5 (MI5x5) |
Primary outcome
Quality-of-life
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Participant quality of life (measured through focus group questions \& SF-36)
8 secondary outcomes
Balance
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
6-minute Walk Test
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Timed-up-and-go
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
30-second sit-to-stand (30s-Sit-to-Stand)
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Strength
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Body Mass Index
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Strength-to-mass Ratio
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Leg press one-rep-max velocity pre-to-post
Time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 May 2025.
- Background: PubMed 35842655Pearson LT, Behm DG, Goodall S, Mason R, Stuart S, Barry G. Effects of maximal-versus submaximal-intent resistance training on functional capacity and strength in community-dwelling older adults: a systematic review and meta-analysis. BMC Sports Sci Med Rehabil. 2022 Jul 16;14(1):129. doi: 10.1186/s13102-022-00526-x.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Leg Press Resistance Training (3x5) and Leg Press Resistance Training (5x5) in people with Quality of Life, run by Northumbria University at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Quality-of-life (time frame: At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06124911, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 May 2025.