CervicalNCT06154993
Comparison of Static and Dynamic Opening With Neural Sliding in Cervical Radiculopathy
A study testing static opening with slider+ Conventional PT and dynamic opener with slider + Conventional PT in people with Cervical and Cervical Radiculopathy, run by Riphah International University at 2 sites in Pakistan.
Trial summary
The aim of this randomized controlled trial is to determine the effects of static and dynamic opening with neural sliding in patients with cervical radiculopathy for reducing pain, enhancing cervical range of motion and improve functional status. Read more about this study
- Who is it for?
- Ages 35 to 60 years
- Conditions the study is for
- Cervical, Cervical Radiculopathy
- What is being tested?
- static opening with slider+ Conventional PT and dynamic opener with slider + Conventional PT
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 2 sitesPakistan
- Study dates
- 3 Aug 2023to 1 Feb 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- : • Spurling +ive
- Distraction test +ive (alleviate symptoms)
- Pain, paresthesia and numbness in Rt/Lt UL in dermatomal pattern of median nerve
- MRI confirmed spondylosis or disc herniation
- Age 35-60
Who cannot join
- • Cervical spine fracture
- RA
- Cervical myelopathy
- Systemic neurological conditions
- Osteoporosis
Trial locations and contacts
2 sites in 1 country.
Pakistan2 sites
RehabWrox
Islamabad, Federal, 44150
Pakistan Railway General Hospital
Rawalpindi, Punjab Province, 04616
About this study
The aim of this randomized controlled trial is to determine the effects of static and dynamic opening with neural sliding in patients with cervical radiculopathy for reducing pain, enhancing cervical range of motion and improve functional status.
Read the detailed description
Static opener is a neurodynamic technique for cervical radiculopathy for reducing pressure on the nervous system that causes intervertebral foramina to remain in the open position for a certain period. This enables blood flow to return to neural tissue so that oxygenation is improved, along with slider mobilization will reduce symptoms and give better healing to the inflamed nerve. when the intervertebral foramina remain open for a considerable amount of time axoplasmic flow is reestablished, oxygenation is improved, increases blood flow along with venous return and nerve gets more nutrients and all the inflammatory exudate is taken off resulting for early improvement.
Dynamic opener is a neurodynamic technique in opening direction to repetitively open and close the intervertebral foramina and produces oscillatory movements that cause pumping effect on the nerve and help to drain edema due to inflammation and help reduce pain and increase the range also.
- Conditions
- Cervical, Cervical Radiculopathy
- Being tested
- static opening with slider+ Conventional PT, dynamic opener with slider + Conventional PT
- Keywords
- cervical radiculopathy, static opener, dynamic opener, slider neurodynamic
- Medical subject headings
- Radiculopathy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
static opening with slider+ Conventional PTOther
Patient supine Maintaining neck flexion + contralateral flexion and rotation and applying median nerve slider mobilization while maintaining the neck static in mentioned position.
Frequency: 3 sets of 10 reps with 5 sec hold for 3 times/week for 4 weeks Conventional PT includes hot pack for 10 mins and cervical isometrics. Frequency: 3 sets of 10 reps with 5 sec hold for 3 times/week for 4 weeks.
Duration: 30-40 mins
dynamic opener with slider + Conventional PTOther
Patient supine Neck flexion + contralateral flexion and rotation. And sliding the median nerve along with neck movement from contralateral flexion+rotation to neutal position in repetitive manner, by releasing tension from median nerve when bringing neck in neutral to ease tension from affected side.
Conventional PT includes hot pack for 10 mins and cervical isometrics. Frequency: 3 sets of 10 reps with 5 sec hold for 3 times/week for 4 weeks.
Duration: 30-40 mins
| Study group | Role | What they receive |
|---|---|---|
| static opener with slider + Conventional PT | Experimental | Patient supine Maintaining neck flexion + contralateral flexion and rotation and applying median nerve slider mobilization while maintaining the neck static in mentioned position.
Conventional PT includes hot pack for 10 mins and cervical isometrics. Receives: Other: static opening with slider+ Conventional PT |
| dynamic opener with slider + Conventional PT | Experimental | Patient supine Neck flexion + contralateral flexion and rotation. And sliding the median nerve along with neck movement from contralateral flexion+rotation to neutal position in repetitive manner, by releasing tension from median nerve when bringing neck in neutral to ease tension from affected side.
Conventional PT includes hot pack for 10 mins and cervical isometrics. Receives: Other: dynamic opener with slider + Conventional PT |
What is being measured
The primary outcome is the main question the study is designed to answer.
neck disability index
Most used questionnaire for disability in patient related to any musculoskeletal neck condition. It has 7 items for daily living, 2 for pain and 1 for concentration. Each item is rated from 0 to 5. Total score is presented in percentage. Higher score tells greater disability while 0 means no disability. Total score is 50.
Measured: 4 weeks
visual analogue scale
VAS is a commonly used assessment tool for pain intensity ranging from 0 to 100mm on a horizontal scale while patient marks a vertical line to rank his/her pain.
0-4mm no pain 5-44mm mild pain 45-74mm moderate pain 75-100mm severe pain
Measured: 4 weeks
inclinometer
A device used to check range of motion based on gravity.
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Dec 2023
- Study start3 Aug 2023
- Primary completion1 Dec 2023
- Study completion1 Feb 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CervicalStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Affan Iqbal, Phd*, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06154993
- Sponsor's protocol ID
- S22C08G30001
- Status last verified
- Apr 2025
- First submitted
- 24 Nov 2023
- Last updated
- 29 Apr 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Static and Dynamic Opening With Neural Sliding in Cervical Radiculopathy
- ClinicalTrials.gov ID
- NCT06154993
- Acronym / sponsor ID
- S22C08G30001
- Conditions
- Cervical, Cervical Radiculopathy
- Keywords
- cervical radiculopathy, static opener, dynamic opener, slider neurodynamic
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 3 Aug 2023 (actual)
- Primary completion
- 1 Dec 2023 (actual)
- Study completion
- 1 Feb 2024 (actual)
- First posted
- 4 Dec 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this randomized controlled trial is to determine the effects of static and dynamic opening with neural sliding in patients with cervical radiculopathy for reducing pain, enhancing cervical range of motion and improve functional status.
Detailed description
Static opener is a neurodynamic technique for cervical radiculopathy for reducing pressure on the nervous system that causes intervertebral foramina to remain in the open position for a certain period. This enables blood flow to return to neural tissue so that oxygenation is improved, along with slider mobilization will reduce symptoms and give better healing to the inflamed nerve. when the intervertebral foramina remain open for a considerable amount of time axoplasmic flow is reestablished, oxygenation is improved, increases blood flow along with venous return and nerve gets more nutrients and all the inflammatory exudate is taken off resulting for early improvement.
Dynamic opener is a neurodynamic technique in opening direction to repetitively open and close the intervertebral foramina and produces oscillatory movements that cause pumping effect on the nerve and help to drain edema due to inflammation and help reduce pain and increase the range also.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| static opener with slider + Conventional PT | Experimental | Other: static opening with slider+ Conventional PTPatient supine Maintaining neck flexion + contralateral flexion and rotation and applying median nerve slider mobilization while maintaining the neck static in mentioned position. Conventional PT includes hot pack for 10 mins and cervical isometrics. |
| dynamic opener with slider + Conventional PT | Experimental | Other: dynamic opener with slider + Conventional PTPatient supine Neck flexion + contralateral flexion and rotation. And sliding the median nerve along with neck movement from contralateral flexion+rotation to neutal position in repetitive manner, by releasing tension from median nerve when bringing neck in neutral to ease tension from affected side. Conventional PT includes hot pack for 10 mins and cervical isometrics. |
Who may qualify
- Ages
- 35 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- : • Spurling +ive
Key exclusion criteria (5 listed)
- • Cervical spine fracture
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| static opening with slider+ Conventional PTPatient supine Maintaining neck flexion + contralateral flexion and rotation and applying median nerve slider mobilization while maintaining the neck static in mentioned position. Frequency: 3 sets of 10 reps with 5 sec hold for 3 times/week for 4 weeks Conventional PT includes hot pack for 10 mins and cervical isometrics. Frequency: 3 sets of 10 reps with 5 sec hold for 3 times/week for 4 weeks. Duration: 30-40 mins | Other | static opener with slider + Conventional PT |
| dynamic opener with slider + Conventional PTPatient supine Neck flexion + contralateral flexion and rotation. And sliding the median nerve along with neck movement from contralateral flexion+rotation to neutal position in repetitive manner, by releasing tension from median nerve when bringing neck in neutral to ease tension from affected side. Conventional PT includes hot pack for 10 mins and cervical isometrics. Frequency: 3 sets of 10 reps with 5 sec hold for 3 times/week for 4 weeks. Duration: 30-40 mins | Other | dynamic opener with slider + Conventional PT |
Primary outcome
neck disability index
Time frame: 4 weeks
Most used questionnaire for disability in patient related to any musculoskeletal neck condition. It has 7 items for daily living, 2 for pain and 1 for concentration. Each item is rated from 0 to 5. Total score is presented in percentage. Higher score tells greater disability while 0 means no disability. Total score is 50.
visual analogue scale
Time frame: 4 weeks
VAS is a commonly used assessment tool for pain intensity ranging from 0 to 100mm on a horizontal scale while patient marks a vertical line to rank his/her pain. 0-4mm no pain 5-44mm mild pain 45-74mm moderate pain 75-100mm severe pain
inclinometer
Time frame: 4 weeks
A device used to check range of motion based on gravity.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Apr 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Affan Iqbal, Phd* principal investigator
Riphah International University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing static opening with slider+ Conventional PT and dynamic opener with slider + Conventional PT in people with Cervical and Cervical Radiculopathy, run by Riphah International University at 2 sites in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
neck disability index (time frame: 4 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Apr 2025.