Clinical trials: Cervical
Endometrial Neoplasms, DNA Methylation
Cervical Cytology DNA Methylation for Endometrial Lesion Screening and Follow-up
The goal of this observational study is to evaluate the accuracy of a novel molecular test for screening and monitoring endometrial lesions in women at medium-to-high risk for endometrial cancer.
- Conditions
- Endometrial Neoplasms, DNA Methylation, Cervical Smears, Early Detection of Cancer
- Trial name
- EndoMethy-V (NCT07298707)
- Volunteers
- 3,500 people
- Sponsor
- Peking Union Medical College Hospital
Labor Pain, Pregnancy Loss
Cervical Capsaicin for Labor Induction and Pain Relief
In the setting of fetal demise it is important to help the mother deliver the fetus expeditiously and with as little physical trauma as possible.
- Conditions
- Labor Pain, Pregnancy Loss, Labor Induction
- Trial name
- NCT00771511
- Testing
- capsaicin
- Sponsor
- Columbia University
Femoral Neck Fractures, Periprosthetic Fractures
Postoperative Periprosthetic Fractures in Hip Fracture Patients: Exeter vs Anatomic SP2 Lubinus Stem
Recent studies have indicated a high incidence of postoperative periprosthetic femoral fracture in elderly patients treated with two commonly used cemented polished, tapered femoral stems.
- Trial name
- PPFEvL (NCT03326271)
- Testing
- Exeter stem, Lubinus SP2 stem
- Volunteers
- 2,527 people
- Sponsor
- Sundsvall Hospital
Radiodermatitis
Evaluation of Therapeutic Efficacy in Use of Chamomilla Gel, Chamomilla Infuse and Urea in Radiodermatitis
This study aims to evaluate therapeutics interventions in radiodermatitis in patients with breast or head and neck cancer. The data collect is going to begin after determining the better dose in a dose-response curve that is…
- Trial name
- ChamomillaTH (NCT02251392)
- Testing
- Chamomila recutita Gel, Chamomila recutita Infuse, Urea cream based
- Volunteers
- 100 people
- Sponsor
- University of Brasilia
Neck Pain
Neck Motion and Motor Control in Chronic Neck Pain and Associations With Clinical Symptoms
The primary purpose of this study is to investigate if there is altered motor control of head and neck in chronic neck pain patients compared with healthy persons.
- Trial name
- NCT01778036
- Where
- 2 sites in Norway
- Volunteers
- 84 people
- Sponsor
- Norwegian University of Science and Technology
Dysphagia, Esophageal, Esophageal Cancer
Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer
This study validates 3 well known dysphagia scores for dysphagia due to malignancies of the oesophagus and gastro-oesophageal junction and to the Swedish language.
- Trial name
- NCT03066167
- Testing
- Validation of different dysphagia scores
- Where
- Sweden
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Head and Neck Squamous Cell Carcinoma
Postoperative Radiotherapy With Nimotuzumab ± Benmelstobart in Intermediate-Risk Head and Neck Squamous Cell Carcinoma
A multicenter, randomized, controlled, open-label, Phase II/III clinical trial designed to evaluate the efficacy and safety of postoperative radiotherapy combined with Nimotuzumab,with or without Bemcentinib, in postoperative…
- Trial name
- NimoBenSeq (NCT07535567)
- Testing
- Nimotuzumab, Nimotuzumab, Benmelstobart, Postoperative Radiotherapy
- Volunteers
- 386 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Esophageal Cancer
Cologne Esophageal Response Prediction Study (CERP-Study)
RATIONALE: The prognosis of patients with advanced esophageal cancer may be improved by preoperative chemoradiation. But only those patients have a benefit from this additional therapy, whose tumor shows a response after…
- Trial name
- CERP (NCT00953511)
- Testing
- ERCC1 pathways analysis
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Elfriede Bollschweiler
Stage I Esophageal Adenocarcinoma, Stage II Esophageal Adenocarcinoma
Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer
The therapy of photofrin PDT was effective in improving life quality of patients with advanced esophageal and/or gastric cardiac cancer and the time optimizing for employing laser irradiation was of great importance.The purpose…
- Conditions
- Stage I Esophageal Adenocarcinoma, Stage II Esophageal Adenocarcinoma, Stage III Esophageal Adenocarcinoma, Stage I Esophageal Squamous Cell Carcinoma
- Trial name
- NCT02628665
- Testing
- photosensitizer(photofrin), 630 nm laser irradiation (DIOMED)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital of Henan University of Science and Technology
Colon Cancer, Lung Cancer
A Pilot, Open-label Study of 18F-Fluciclatide PET/CT Imaging in the Evaluation of Anti-angiogenic Therapy in Solid Tumors
Background: Fluciclatide is a small cyclic peptide containing the RGD tri-peptide, which preferentially binds with high affinity to alpha(v)beta(3) integrins, which are up-regulated in and may regulate angiogenesis.
- Conditions
- Colon Cancer, Lung Cancer, Cervical Cancer, Renal Cell Carcinoma
- Trial name
- NCT01176500
- Testing
- (18)Fluciclatide
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Femoral Neck Fractures
Vertical Femoral Neck Fractures in Young Adult Patients
Does the current techniques of internal fixation of vertical neck fracture in young adult patients give a satisfactory radiological and functional outcome at one year follow up?
- Trial name
- NCT04687592
- Testing
- reduction and fixation
- Volunteers
- 30 people
- Sponsor
- Assiut University
Cervical Myelopathy
Are Rigid Cervical Collars Necessary for Open-door Laminoplasty and Titanium Arch Plates for Cervical Myelopathy?
This is a randomized controlled trial to assess the use of rigid neck collar postoperatively. It consists of patients with cervical myelopathy undergoing open-door laminoplasty with titanium arch plates.
- Trial name
- NCT03400644
- Testing
- Cervical collar
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- The University of Hong Kong
Disease Free Survival
A Study on the Efficacy and Safety of Bevacizumab in Untreated Patients With Locally Advanced Cervical Cancer
To verify the clinical efficacy and safety of bevacizumab in treating local advanced cervical cancer, present study was designed to investigate the clinical results of bevacizumab combined with concurrent chemoradiotherapy (CCRT)…
- Trial name
- NCT04138992
- Testing
- bevacizumab, DDP, Docetaxel
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Air Force Military Medical University, China
Head and Neck Squamous Cell Carcinoma
FID-007 and Cetuximab in Treating Patients With Advanced Head and Neck Squamous Cell Carcinoma
The goal of this FID-007 Clinical Trial is to compare the efficacy of different dosing regimens of FID-007 in combination with Cetuximab in patients with recurrent or metastatic Head and Neck Squamous Cell Carcinoma (HNSCC).
- Trial name
- HNSCC (NCT06332092)
- Testing
- FID007
- Where
- 6 sites in United States
- Volunteers
- 46 people
- Sponsor
- Fulgent Pharma LLC.
Myofascial Temporomandibular Disorder, Bruxism, Sleep
Factors Affecting Patients With Myofascial Temporomandibular Disorders
The aim of the study was to assess and compare the relationship between jaw function, neck disability, sleep quality, fatigue, and headache in patients with myofascial Temporomandibular Disorder (TMD) with Sleep Bruxism (SB) and…
- Conditions
- Myofascial Temporomandibular Disorder, Bruxism, Sleep, Sleep Disturbance, Jaw Spasm
- Trial name
- NCT04842136
- Testing
- Scales and indexes
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Cervical Cancer
A Study of INO-3112 DNA Vaccine With Electroporation in Participants With Cervical Cancer
This is an open-label study to evaluate the safety, tolerability, and immunogenicity of INO-3112 DNA vaccines delivered by electroporation (EP) to female participants with HPV-16 and/or 18-positive cervical carcinoma.
- Trial name
- NCT02172911
- Testing
- INO-3112, CELLECTRA™-5P
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Inovio Pharmaceuticals
Thyroid Papillary Carcinoma, Contrast Enhanced Ultrasound
Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced Ultrasound
Similarly, the burden of central lymph node metastasis affects the individualized management of patients with T1N0M0 papillary thyroid carcinoma (PTC): lymph node metastasis is a contraindication to thermal ablation; low-burden…
- Trial name
- NCT07357571
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Multimoda Lultasound, Thyroid Cancer
Multimodality US Based on Angio Planewave Ultrasensitive Imaging and Shear Wave Elastography to Evaluate the Malignancy Risk Value of Thyroid Nodules
The goal of this clinical trial is to explore the value of a multimodal ultrasound model based on Angio Planewave Ultrasensitive Imaging, Shear Wave Elastography and grayscale ultrasound in the differential diagnosis of benign…
- Conditions
- Multimoda Lultasound, Thyroid Cancer, Microvascular Classification
- Trial name
- NCT06530771
- Testing
- ultrasound
- Where
- China
- Volunteers
- 720 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Advanced Cancer, Advanced Malignancies
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
The primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.
- Conditions
- Advanced Cancer, Advanced Malignancies, Bladder Cancer, Cervical Cancer
- Trial name
- ARC-25 (NCT05891171)
- Testing
- AB598, Zimberelimab, Fluorouracil
- Where
- 14 sites in United States, Australia and 1 more
- Volunteers
- 40 people
- Sponsor
- Arcus Biosciences, Inc.
Head and Neck Cancer
Docetaxel + Cetuximab + Concurrent Re-Irradiation (Intensity - Modulated Radiation Therapy, IMRT) for Patients With Locoregionally Recurrent Head and Neck Cancer
This is a study for patients who have head and neck cancer that has recurred in the body area where they previously received radiation, and for whom surgery is not planned.
- Trial name
- NCT00713219
- Testing
- IMRT, cetuximab, docetaxel
- Where
- 6 sites in United States
- Volunteers
- 14 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
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