Horizontal Bone AugmentationNCT06195761
Computer Guided Modified Ridge Splitting Versus Free Hand Technique in Horizontal Deficiency in Posterior Mandible
A study testing computer guided modified ridge splitting technique in horizontal bone deficiency in posterior mandible and free hand modified ridge splitting technique in horizontal bone deficiency in posterior mandible in people with Horizontal Bone Augmentation and Horizontal Ridge Deficiency, run by Cairo University at 1 site in Egypt.
Trial summary
To assess the accuracy of the computer assessed guides in horizontal bone augmentation achieved at posterior mandible using guided modified ridge splitting technique versus free hand modified ridge splitting technique Read more about this study
- Who is it for?
- Ages 25 to 55 yearsHealthy volunteers can take part
- Conditions the study is for
- Horizontal Bone Augmentation, Horizontal Ridge Deficiency
- What is being tested?
- computer guided modified ridge splitting technique in horizontal bone deficiency in posterior mandible and free hand modified ridge splitting technique in horizontal bone deficiency in posterior mandible
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 18 participants
- Where
- 1 siteEgypt
- Study dates
- 15 May 2026to 15 Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 55 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- posterior mandible with horizontal deficient alveolar ridge that is from 2 to 4 mm measured from the crest of the alveolar ridge buccolingually
- Age range from 25-55 years. No sex predilection.
- Patients free from any systemic conditions and bone metabolism diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.
- Patients of adequate alveolar bone width.
- Both genders males and females will be included
- Normal vertical dimension with normal inter-arch space. The minimum number of missing teeth in the posterior mandible alveolar ridge is two adjacent anterior teeth
Who cannot join
- Intra-bony lesions (e.g. cysts) or infections (e.g. abscess) that may retard the osteotomy healing.
- Previous grafting procedures in the edentulous area.
- General contraindications to implant surgery.
- Subjected to irradiation in the head and neck area less than 1 year before implantation.
- Untreated periodontitis.
- Poor oral hygiene and motivation.
Show all 11Show fewer
- Uncontrolled diabetes.
- Pregnant or nursing.
- Immunosuppressed or immunocompromised
- Heavy smokers
- Patients undergo medication interfere with bone healing
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Radiographic Assessment of Computer Guided Modified Ridge Splitting Technique Versus Conventional Free Hand Technique in Management of Horizontal Deficiency in Posterior Mandible: a Randomized Control Clinical Trial
To assess the accuracy of the computer assessed guides in horizontal bone augmentation achieved at posterior mandible using guided modified ridge splitting technique versus free hand modified ridge splitting technique
Read the detailed description
The first treatment plan includes harvesting and fixing the bone graft in posterior mandibular area using a computer-modified surgical guide.
The second treatment plan includes manually harvesting and fixing the bone graft in posterior mandibular area without a surgical guide.
- Being tested
- computer guided modified ridge splitting technique in horizontal bone deficiency in posterior mandible, free hand modified ridge splitting technique in horizontal bone deficiency in posterior mandible
- Keywords
- computer guided modified ridge splitting, computer guided modified cortical shell technique, guided modified ridge splitting in posterior mandible
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
computer guided modified ridge splitting technique in horizontal bone deficiency in posterior mandibleProcedure or surgery
Also called computer guided modified cortical shell technique
treatment plan includes harvesting and fixing the bone graft in posterior mandibular area using a computer-modified surgical guide
free hand modified ridge splitting technique in horizontal bone deficiency in posterior mandibleProcedure or surgery
Also called conventional modified cortical shell technique
treatment plan includes manually harvesting and fixing the bone graft in posterior mandibular area without a surgical guide.
| Study group | Role | What they receive |
|---|---|---|
| computer guided modified ridge splitting technique (study group) | Experimental | The first treatment plan includes harvesting and fixing the bone graft in posterior mandibular area using a computer-modified surgical guide. Receives: Procedure: computer guided modified ridge splitting technique in horizontal bone deficiency in posterior mandible |
| conventional modified ridge splitting technique (control group) | Experimental | The second treatment plan includes manually harvesting and fixing the bone graft in posterior mandibular area without a surgical guide Receives: Procedure: free hand modified ridge splitting technique in horizontal bone deficiency in posterior mandible |
What is being measured
The primary outcome is the main question the study is designed to answer.
Accuracy of the Computer Assessed Guide in the study group
Accuracy of the Computer Assessed Guide in the study group In comparison with the control group between predicted and immediately postoperative horizontal bone width with Cone beam computed tomography in Millimeters measurement tool is CBCT scan superimposition in mm
Measured: immediately postoperative
Secondary outcomes (1)
Alveolar ridge horizontal bone gain
measure the amount of horizontal bone width gaining by postoperative cone beam computed tomography in millimeters measurement tool is CBCT scan superimposition in mm
Measured: 4 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jan 2024
- Study start15 May 2026 (estimated)
- Primary completion15 May 2026 (estimated)
- Study completion15 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Horizontal Bone AugmentationStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- treatment plan includes harvesting and fixing the bone graft in posterior mandibular area using a computer-modified surgical guide
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 18 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mina ElHadidi Sobhi Ramzi Michael, Cairo University
- Investigators
- Mohamed Mounir Shaker, BDS,MSc,PHD, Study chair, Cairo UniversityRofaida Atef Abaas, BDS,MSc,PHD, Study director, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06195761
- Sponsor's protocol ID
- computer guided modified ridge
- Status last verified
- Jan 2026
- First submitted
- 23 Dec 2023
- Last updated
- 16 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Al-Ani O, Nambiar P, Ha KO, Ngeow WC. Safe zone for bone harvesting from the interforaminal region of the mandible. Clin Oral Implants Res. 2013 Aug;24 Suppl A100:115-21. doi: 10.1111/j.1600-0501.2011.02393.x. Epub 2012 Jan 11.
PubMed 22233422Sanchez-Labrador L, Molinero-Mourelle P, Perez-Gonzalez F, Saez-Alcaide LM, Brinkmann JC, Martinez JL, Martinez-Gonzalez JM. Clinical performance of alveolar ridge augmentation with xenogeneic bone block grafts versus autogenous bone block grafts. A systematic review. J Stomatol Oral Maxillofac Surg. 2021 Jun;122(3):293-302. doi: 10.1016/j.jormas.2020.10.009. Epub 2020 Nov 5.
PubMed 33161168De Stavola L, Fincato A, Bressan E, Gobbato L. Results of Computer-Guided Bone Block Harvesting from the Mandible: A Case Series. Int J Periodontics Restorative Dent. 2017 Jan/Feb;37(1):e111-e119. doi: 10.11607/prd.2721.
PubMed 27977816Schwartz-Arad D, Levin L, Sigal L. Surgical success of intraoral autogenous block onlay bone grafting for alveolar ridge augmentation. Implant Dent. 2005 Jun;14(2):131-8. doi: 10.1097/01.id.0000165031.33190.0d.
PubMed 15968184Assaf A, Saad M, Daas M, Abdallah J, Abdallah R. Use of narrow-diameter implants in the posterior jaw: a systematic review. Implant Dent. 2015 Jun;24(3):294-306. doi: 10.1097/ID.0000000000000238.
PubMed 25851960
Study at a glance
From the registry record, last updated by the sponsor on 16 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Radiographic Assessment of Computer Guided Modified Ridge Splitting Technique Versus Conventional Free Hand Technique in Management of Horizontal Deficiency in Posterior Mandible: a Randomized Control Clinical Trial
- ClinicalTrials.gov ID
- NCT06195761
- Acronym / sponsor ID
- computer guided modified ridge
- Keywords
- computer guided modified ridge splitting, computer guided modified cortical shell technique, guided modified ridge splitting in posterior mandible
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 18 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 15 May 2026 (estimated)
- Primary completion
- 15 May 2026 (estimated)
- Study completion
- 15 Jun 2026 (estimated)
- First posted
- 8 Jan 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To assess the accuracy of the computer assessed guides in horizontal bone augmentation achieved at posterior mandible using guided modified ridge splitting technique versus free hand modified ridge splitting technique
Detailed description
The first treatment plan includes harvesting and fixing the bone graft in posterior mandibular area using a computer-modified surgical guide.
The second treatment plan includes manually harvesting and fixing the bone graft in posterior mandibular area without a surgical guide.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- treatment plan includes harvesting and fixing the bone graft in posterior mandibular area using a computer-modified surgical guide
| Arm | Type | Receives |
|---|---|---|
| computer guided modified ridge splitting technique (study group) | Experimental | Procedure: computer guided modified ridge splitting technique in horizontal bone deficiency in posterior mandibleThe first treatment plan includes harvesting and fixing the bone graft in posterior mandibular area using a computer-modified surgical guide. |
| conventional modified ridge splitting technique (control group) | Experimental | Procedure: free hand modified ridge splitting technique in horizontal bone deficiency in posterior mandibleThe second treatment plan includes manually harvesting and fixing the bone graft in posterior mandibular area without a surgical guide |
Who may qualify
- Ages
- 25 to 55 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- posterior mandible with horizontal deficient alveolar ridge that is from 2 to 4 mm measured from the crest of the alveolar ridge buccolingually
- Age range from 25-55 years. No sex predilection.
- Patients free from any systemic conditions and bone metabolism diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.
- Patients of adequate alveolar bone width.
- Both genders males and females will be included
Key exclusion criteria (11 listed)
- Intra-bony lesions (e.g. cysts) or infections (e.g. abscess) that may retard the osteotomy healing.
- Previous grafting procedures in the edentulous area.
- General contraindications to implant surgery.
- Subjected to irradiation in the head and neck area less than 1 year before implantation.
- Untreated periodontitis.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| computer guided modified ridge splitting technique in horizontal bone deficiency in posterior mandibleAlso: computer guided modified cortical shell techniquetreatment plan includes harvesting and fixing the bone graft in posterior mandibular area using a computer-modified surgical guide | Procedure or surgery | computer guided modified ridge splitting technique (study group) |
| free hand modified ridge splitting technique in horizontal bone deficiency in posterior mandibleAlso: conventional modified cortical shell techniquetreatment plan includes manually harvesting and fixing the bone graft in posterior mandibular area without a surgical guide. | Procedure or surgery | conventional modified ridge splitting technique (control group) |
Primary outcome
Accuracy of the Computer Assessed Guide in the study group
Time frame: immediately postoperative
Accuracy of the Computer Assessed Guide in the study group In comparison with the control group between predicted and immediately postoperative horizontal bone width with Cone beam computed tomography in Millimeters measurement tool is CBCT scan superimposition in mm
1 secondary outcome
Alveolar ridge horizontal bone gain
Time frame: 4 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jan 2026.
- Results publication: PubMed 22233422Al-Ani O, Nambiar P, Ha KO, Ngeow WC. Safe zone for bone harvesting from the interforaminal region of the mandible. Clin Oral Implants Res. 2013 Aug;24 Suppl A100:115-21. doi: 10.1111/j.1600-0501.2011.02393.x. Epub 2012 Jan 11.
- Results publication: PubMed 33161168Sanchez-Labrador L, Molinero-Mourelle P, Perez-Gonzalez F, Saez-Alcaide LM, Brinkmann JC, Martinez JL, Martinez-Gonzalez JM. Clinical performance of alveolar ridge augmentation with xenogeneic bone block grafts versus autogenous bone block grafts. A systematic review. J Stomatol Oral Maxillofac Surg. 2021 Jun;122(3):293-302. doi: 10.1016/j.jormas.2020.10.009. Epub 2020 Nov 5.
- Results publication: PubMed 27977816De Stavola L, Fincato A, Bressan E, Gobbato L. Results of Computer-Guided Bone Block Harvesting from the Mandible: A Case Series. Int J Periodontics Restorative Dent. 2017 Jan/Feb;37(1):e111-e119. doi: 10.11607/prd.2721.
- Results publication: PubMed 15968184Schwartz-Arad D, Levin L, Sigal L. Surgical success of intraoral autogenous block onlay bone grafting for alveolar ridge augmentation. Implant Dent. 2005 Jun;14(2):131-8. doi: 10.1097/01.id.0000165031.33190.0d.
- Results publication: PubMed 25851960Assaf A, Saad M, Daas M, Abdallah J, Abdallah R. Use of narrow-diameter implants in the posterior jaw: a systematic review. Implant Dent. 2015 Jun;24(3):294-306. doi: 10.1097/ID.0000000000000238.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mohamed Mounir Shaker, BDS,MSc,PHD study chair
Cairo University
Rofaida Atef Abaas, BDS,MSc,PHD study director
Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing computer guided modified ridge splitting technique in horizontal bone deficiency in posterior mandible and free hand modified ridge splitting technique in horizontal bone deficiency in posterior mandible in people with Horizontal Bone Augmentation and Horizontal Ridge Deficiency, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 16 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mina ElHadidi Sobhi Ramzi, BDS (+201225339712, mina.ramzi@dentistry.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Accuracy of the Computer Assessed Guide in the study group (time frame: immediately postoperative). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06195761, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jan 2026.