Small Bowel ObstructionNGTUBE-OBSNCT06262815
The Utility of Treatment With Nasogastric Tube Placement for Small Bowel Obstruction
An observational study of Small Bowel Obstruction and Frailty, run by Daniel Wilhelms at 8 sites in Sweden.
Trial summary
Small bowel obstruction (SBO) occurs when the normal movements of the small bowel is obstructed, most commonly due to adhesion related to previous abdominal surgery. This may cause strangulation of the small bowel with reduced blood flow which is a surgical emergency requiring prompt treatment in the operating room. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Small Bowel Obstruction, Frailty, Nasogastric Tube
- What is being tested?
- Nasogastric tube placement and Clinical Frailty Scale
- Type of treatment
- Surgery or procedure
- How many people
- 400 participants
- Where
- 8 sitesSweden
- Study dates
- 1 Jan 2024to 31 May 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Patients visiting any of the following Emergency Departments in Sweden: * Linköping University Hospital * Motala Lasarett * Vrinnevisjukhuset Norrköping * Sundvalls Lasarett * Skåne University Hospital Malmö * Skåne University Hospital Lund * Sahlgrenska University Hospital Sahlgrenska * Sahlgrenska University Hospital Östra
Who may be able to join
- Diagnosed small bowel obstruction
- Age 18 or older
Who cannot join
- Abdominal surgery within 7 days
- Not able to give informed consent
Trial locations and contacts
8 sites in 1 country.
8 sites in 1 country
Sweden8 sites
Sahlgrenska Universitetssjukhuset
Gothenburg
Östra sjukhuset
Gothenburg
Akutmottagningen US Östergötland
Linköping, Östergötland County, 58185
Skånes Universitetssjukhus
Lund
Skånes Universitetssjukhus
Malmö
Lasarett i Motala
Motala
Vrinnevisjukhuset
Norrköping
Sundsvalls sjukhus
Sundsvall
About this study
Official title: The Utility of Treatment With Nasogastric Tube Placement for Small Bowel Obstruction in Adult Patients in the Emergency Department; an Observational Multicenter Study
Small bowel obstruction (SBO) occurs when the normal movements of the small bowel is obstructed, most commonly due to adhesion related to previous abdominal surgery. This may cause strangulation of the small bowel with reduced blood flow which is a surgical emergency requiring prompt treatment in the operating room. If there are no signs of strangulation or ischemia of the bowel at the time of diagnosis, international guidelines recommend initial treatment with intravenous fluids and nasogastric tube placement. However, there is emerging debate regarding non-selective treatment with nasogastric tube placement in patients with SBO. This management started around 1930 as a means to reduce pain in patients with SBO, in conjunction with other additions to management, like intravenous fluids. However the effect and utility of routine nasogastric tube placement have not been prospectively evaluated. There are a total of three retrospective observational studies in the past decade with a total of 759 patients where 292 (36%) were managed without a nasogastric tube. There was no difference in the rates of conservative treatment failure (requiring surgery), complications (vomiting, pneumonia) or mortality between patients receiving a nasogastric tube and those who didn't. However, the retrospective design of these studies limits their validity. Furthermore, nasogastric tube placement has been shown to be one of the more painful interventions patients may experience in-hospital. This calls into question the patient benefit of routine nasogastric tube placement in patients with SBO and further studies are needed to discern the utility of this intervention.
Definitive treatment for SBO is surgical adhesiolysis but there is debate regarding the timing of surgery, particularly in older adults. A large proportion of patients may be managed conservatively with oral contrast and repeated radiological evaluation and the obstruction will resolve in many patients within 24 to 48 hours. This timeframe is dependent on factors related to the disease itself as well as patient related factors like previous surgery and comorbidities. Older patients are at high risk for complications but current available data is insufficient to inform practice in this population. Frailty, a state of increased vulnerability and susceptibility to adverse events, has been shown to be an independent prognosticator in older adults in the Emergency Department(ED) and suggested as a potential measure to risk stratify older adults with SBO. However to the authors knowledge there is no available data on frailty in older adults with SBO and only one prospective observational trial looking at older adults with SBO. Despite SBO being one of the most common surgical emergencies in older adults.
To investigate the potential benefit of nasogastric tube placement in patients with SBO and the ability of frailty to prognosticate outcomes in older adults better evidence is needed.
- Conditions
- Small Bowel Obstruction, Frailty, Nasogastric Tube
- Being tested
- Nasogastric tube placement, Clinical Frailty Scale
- Keywords
- Small bowel obstruction, nasogastric tube, pain, mortality, morbidity, frailty
- Medical subject headings
- Frailty, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nasogastric tube placementProcedure or surgery
Conventional nasogastric tube placement done for decompression of small bowel obstruction
Clinical Frailty ScaleDiagnostic test
The scale described by Rockwood et al. categorizing patients \>65 years of age on a 9 item scale depending on the frailty.
| Study group | Role | What they receive |
|---|---|---|
| Patients with nasogastric tube treatment | Adult patients with diagnosed small bowel obstruction in the Emergency Department for a nasogastric tube was placed Receives: Procedure: Nasogastric tube placement | |
| Patients without nasogastric tube treatment | Adult patients with diagnosed small bowel obstruction in the Emergency Department for no nasogastric tube was placed Receives: Procedure: Nasogastric tube placement | |
| Patients living with frailty | Subgroup of patients, with small bowel obstruction in the Emergency Department over 65 years of age with a clinical frailty score of \>4. Receives: Diagnostic Test: Clinical Frailty Scale | |
| Patients not living with frailty | Subgroup of patients, with small bowel obstruction in the Emergency Department over 65 years of age with a clinical frailty score of \<5. Receives: Diagnostic Test: Clinical Frailty Scale |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain at Emergency Department discharge
self-reported Pain on a Numeric Rating Scale from 0 to 10 were higher is worse
Measured: at Emergency Department Discharge, assessed up to 48 hours
Secondary outcomes (6)
Nausea at Emergency Department discharge
Nausea as self-reported by patients on a numeric rating scale from 0 to 10 were higher is worse
Measured: at Emergency Department discharge, assessed up to 48 hours
Hospital Length of Stay
Duration of days spent in the hospital by patients with Small Bowel obstruction admitted from the Emergency Department
Measured: Up to 90 days from inclusion
Mortality
Mortality of any cause
Measured: up to 90 days from inclusion
Admission for Small bowel obstruction
Any admission to a hospital in Sweden with a primary discharge diagnosis of small bowel obstruction
Measured: up to 365 days from inclusion in the study
Emergency Surgery
Any emergency operation
Measured: up to 30 days from inclusion
Emergency Department Length of Stay
Length of stay, defined as the time from registration in the Emergency Department to discharge from the Emergency Department at the visit of inclusion.
Measured: up to 7 days from inclusion
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Feb 2024
- Study start1 Jan 2024
- Primary completion31 May 2025
- Study completion31 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (16)Papers the sponsor has linked to this study.
- Other trials for Small Bowel ObstructionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 400 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Daniel Wilhelms
- Sponsor type
- University, hospital or other
- Collaborators
- Linkoeping University
- Responsible party
- Sponsor-investigator, Daniel Wilhelms, University Hospital, Linkoeping
- Investigators
- Daniel B Wilhelms, PhD, Principal investigator, Linkoeping University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06262815
- Sponsor's protocol ID
- 2023-06806-01
- Other IDs
- 2023
- Acronym
- NGTUBE-OBS
- Status last verified
- May 2025
- First submitted
- 29 Dec 2023
- Last updated
- 14 Apr 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Limited (providing full anonymization) data may be provided to other researchers
Publications
Elliott A, Taub N, Banerjee J, Aijaz F, Jones W, Teece L, van Oppen J, Conroy S. Does the Clinical Frailty Scale at Triage Predict Outcomes From Emergency Care for Older People? Ann Emerg Med. 2021 Jun;77(6):620-627. doi: 10.1016/j.annemergmed.2020.09.006. Epub 2020 Dec 13.
PubMed 33328147Rueegg M, Nissen SK, Brabrand M, Kaeppeli T, Dreher T, Carpenter CR, Bingisser R, Nickel CH. The clinical frailty scale predicts 1-year mortality in emergency department patients aged 65 years and older. Acad Emerg Med. 2022 May;29(5):572-580. doi: 10.1111/acem.14460. Epub 2022 Apr 23.
PubMed 35138670Kaeppeli T, Rueegg M, Dreher-Hummel T, Brabrand M, Kabell-Nissen S, Carpenter CR, Bingisser R, Nickel CH. Validation of the Clinical Frailty Scale for Prediction of Thirty-Day Mortality in the Emergency Department. Ann Emerg Med. 2020 Sep;76(3):291-300. doi: 10.1016/j.annemergmed.2020.03.028. Epub 2020 Apr 24.
PubMed 32336486Ozturk E, van Iersel M, Stommel MM, Schoon Y, Ten Broek RR, van Goor H. Small bowel obstruction in the elderly: a plea for comprehensive acute geriatric care. World J Emerg Surg. 2018 Oct 20;13:48. doi: 10.1186/s13017-018-0208-z. eCollection 2018.
PubMed 30377439Koh A, Adiamah A, Chowdhury A, Mohiuddin MK, Bharathan B. Therapeutic Role of Water-Soluble Contrast Media in Adhesive Small Bowel Obstruction: a Systematic Review and Meta-Analysis. J Gastrointest Surg. 2020 Feb;24(2):473-483. doi: 10.1007/s11605-019-04341-7. Epub 2019 Aug 13.
PubMed 31485900Springer JE, Bailey JG, Davis PJ, Johnson PM. Management and outcomes of small bowel obstruction in older adult patients: a prospective cohort study. Can J Surg. 2014 Dec;57(6):379-84. doi: 10.1503/cjs.029513.
PubMed 25421079Hajibandeh S, Hajibandeh S, Panda N, Khan RMA, Bandyopadhyay SK, Dalmia S, Malik S, Huq Z, Mansour M. Operative versus non-operative management of adhesive small bowel obstruction: A systematic review and meta-analysis. Int J Surg. 2017 Sep;45:58-66. doi: 10.1016/j.ijsu.2017.07.073. Epub 2017 Jul 17.
PubMed 28728984Peacock O, Bassett MG, Kuryba A, Walker K, Davies E, Anderson I, Vohra RS; National Emergency Laparotomy Audit (NELA) Project Team. Thirty-day mortality in patients undergoing laparotomy for small bowel obstruction. Br J Surg. 2018 Jul;105(8):1006-1013. doi: 10.1002/bjs.10812. Epub 2018 Mar 30.
PubMed 29603126Kuo YW, Yen M, Fetzer S, Lee JD. Reducing the pain of nasogastric tube intubation with nebulized and atomized lidocaine: a systematic review and meta-analysis. J Pain Symptom Manage. 2010 Oct;40(4):613-20. doi: 10.1016/j.jpainsymman.2010.01.025. Epub 2010 Aug 3.
PubMed 20678892Morrison RS, Ahronheim JC, Morrison GR, Darling E, Baskin SA, Morris J, Choi C, Meier DE. Pain and discomfort associated with common hospital procedures and experiences. J Pain Symptom Manage. 1998 Feb;15(2):91-101.
PubMed 9494307Berman DJ, Ijaz H, Alkhunaizi M, Kulie PE, Vaziri K, Richards LM, Meltzer AC. Nasogastric decompression not associated with a reduction in surgery or bowel ischemia for acute small bowel obstruction. Am J Emerg Med. 2017 Dec;35(12):1919-1921. doi: 10.1016/j.ajem.2017.08.029. Epub 2017 Aug 15.
PubMed 28912083Edlich RF, Woods JA. Wangensteen's transformation of the treatment of intestinal obstruction from empiric craft to scientific discipline. J Emerg Med. 1997 Mar-Apr;15(2):235-41. doi: 10.1016/s0736-4679(96)00351-4.
PubMed 9144067Klingbeil KD, Wu JX, Osuna-Garcia A, Livingston EH. Management of small bowel obstruction and systematic review of treatment without nasogastric tube decompression. Surg Open Sci. 2022 Nov 7;12:62-67. doi: 10.1016/j.sopen.2022.10.002. eCollection 2023 Mar.
PubMed 36992798Shinohara K, Asaba Y, Ishida T, Maeta T, Suzuki M, Mizukami Y. Nonoperative management without nasogastric tube decompression for adhesive small bowel obstruction. Am J Surg. 2022 Jun;223(6):1179-1182. doi: 10.1016/j.amjsurg.2021.11.029. Epub 2021 Dec 2.
PubMed 34872712Ten Broek RPG, Krielen P, Di Saverio S, Coccolini F, Biffl WL, Ansaloni L, Velmahos GC, Sartelli M, Fraga GP, Kelly MD, Moore FA, Peitzman AB, Leppaniemi A, Moore EE, Jeekel J, Kluger Y, Sugrue M, Balogh ZJ, Bendinelli C, Civil I, Coimbra R, De Moya M, Ferrada P, Inaba K, Ivatury R, Latifi R, Kashuk JL, Kirkpatrick AW, Maier R, Rizoli S, Sakakushev B, Scalea T, Soreide K, Weber D, Wani I, Abu-Zidan FM, De'Angelis N, Piscioneri F, Galante JM, Catena F, van Goor H. Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group. World J Emerg Surg. 2018 Jun 19;13:24. doi: 10.1186/s13017-018-0185-2. eCollection 2018.
PubMed 29946347
Study at a glance
From the registry record, last updated by the sponsor on 14 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Utility of Treatment With Nasogastric Tube Placement for Small Bowel Obstruction in Adult Patients in the Emergency Department; an Observational Multicenter Study
- ClinicalTrials.gov ID
- NCT06262815
- Acronym / sponsor ID
- NGTUBE-OBS / 2023-06806-01
- Conditions
- Small Bowel Obstruction, Frailty, Nasogastric Tube
- Keywords
- Small bowel obstruction, nasogastric tube, pain, mortality, morbidity, frailty
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 400 participants (estimated)
- Lead sponsor
- Daniel WilhelmsUniversity, hospital or other
- Collaborators
- Linkoeping University
- Study start
- 1 Jan 2024 (actual)
- Primary completion
- 31 May 2025 (actual)
- Study completion
- 31 May 2026 (estimated)
- First posted
- 16 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Small bowel obstruction (SBO) occurs when the normal movements of the small bowel is obstructed, most commonly due to adhesion related to previous abdominal surgery. This may cause strangulation of the small bowel with reduced blood flow which is a surgical emergency requiring prompt treatment in the operating room. If there are no signs of strangulation or ischemia of the bowel at the time of diagnosis, international guidelines recommend initial treatment with intravenous fluids and nasogastric tube placement. However, there is emerging debate regarding non-selective treatment with nasogastric tube placement in patients with SBO. This management started around 1930 as a means to reduce pain in patients with SBO, in conjunction with other additions to management, like intravenous fluids. However the effect and utility of routine nasogastric tube placement have not been prospectively evaluated. There are a total of three retrospective observational studies in the past decade with a total of 759 patients where 292 (36%) were managed without a nasogastric tube. There was no difference in the rates of conservative treatment failure (requiring surgery), complications (vomiting, pneumonia) or mortality between patients receiving a nasogastric tube and those who didn't. However, the retrospective design of these studies limits their validity. Furthermore, nasogastric tube placement has been shown to be one of the more painful interventions patients may experience in-hospital. This calls into question the patient benefit of routine nasogastric tube placement in patients with SBO and further studies are needed to discern the utility of this intervention.
Definitive treatment for SBO is surgical adhesiolysis but there is debate regarding the timing of surgery, particularly in older adults. A large proportion of patients may be managed conservatively with oral contrast and repeated radiological evaluation and the obstruction will resolve in many patients within 24 to 48 hours. This timeframe is dependent on factors related to the disease itself as well as patient related factors like previous surgery and comorbidities. Older patients are at high risk for complications but current available data is insufficient to inform practice in this population. Frailty, a state of increased vulnerability and susceptibility to adverse events, has been shown to be an independent prognosticator in older adults in the Emergency Department(ED) and suggested as a potential measure to risk stratify older adults with SBO. However to the authors knowledge there is no available data on frailty in older adults with SBO and only one prospective observational trial looking at older adults with SBO. Despite SBO being one of the most common surgical emergencies in older adults.
To investigate the potential benefit of nasogastric tube placement in patients with SBO and the ability of frailty to prognosticate outcomes in older adults better evidence is needed.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Patients with nasogastric tube treatment | – | Procedure: Nasogastric tube placementAdult patients with diagnosed small bowel obstruction in the Emergency Department for a nasogastric tube was placed |
| Patients without nasogastric tube treatment | – | Procedure: Nasogastric tube placementAdult patients with diagnosed small bowel obstruction in the Emergency Department for no nasogastric tube was placed |
| Patients living with frailty | – | Diagnostic Test: Clinical Frailty ScaleSubgroup of patients, with small bowel obstruction in the Emergency Department over 65 years of age with a clinical frailty score of \>4. |
| Patients not living with frailty | – | Diagnostic Test: Clinical Frailty ScaleSubgroup of patients, with small bowel obstruction in the Emergency Department over 65 years of age with a clinical frailty score of \<5. |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients visiting any of the following Emergency Departments in Sweden: * Linköping University Hospital * Motala Lasarett * Vrinnevisjukhuset Norrköping * Sundvalls Lasarett * Skåne University Hospital Malmö * Skåne University Hospital Lund * Sahlgrenska University Hospital Sahlgrenska * Sahlgrenska University Hospital Östra
Key inclusion criteria (2 listed)
- Diagnosed small bowel obstruction
- Age 18 or older
Key exclusion criteria (2 listed)
- Abdominal surgery within 7 days
- Not able to give informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nasogastric tube placementConventional nasogastric tube placement done for decompression of small bowel obstruction | Procedure or surgery | Patients with nasogastric tube treatment, Patients without nasogastric tube treatment |
| Clinical Frailty ScaleThe scale described by Rockwood et al. categorizing patients \>65 years of age on a 9 item scale depending on the frailty. | Diagnostic test | Patients living with frailty, Patients not living with frailty |
Primary outcome
Pain at Emergency Department discharge
Time frame: at Emergency Department Discharge, assessed up to 48 hours
self-reported Pain on a Numeric Rating Scale from 0 to 10 were higher is worse
6 secondary outcomes
Nausea at Emergency Department discharge
Time frame: at Emergency Department discharge, assessed up to 48 hours
Hospital Length of Stay
Time frame: Up to 90 days from inclusion
Mortality
Time frame: up to 90 days from inclusion
Admission for Small bowel obstruction
Time frame: up to 365 days from inclusion in the study
Emergency Surgery
Time frame: up to 30 days from inclusion
Emergency Department Length of Stay
Time frame: up to 7 days from inclusion
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Apr 2026.
- Background: PubMed 33328147Elliott A, Taub N, Banerjee J, Aijaz F, Jones W, Teece L, van Oppen J, Conroy S. Does the Clinical Frailty Scale at Triage Predict Outcomes From Emergency Care for Older People? Ann Emerg Med. 2021 Jun;77(6):620-627. doi: 10.1016/j.annemergmed.2020.09.006. Epub 2020 Dec 13.
- Background: PubMed 35138670Rueegg M, Nissen SK, Brabrand M, Kaeppeli T, Dreher T, Carpenter CR, Bingisser R, Nickel CH. The clinical frailty scale predicts 1-year mortality in emergency department patients aged 65 years and older. Acad Emerg Med. 2022 May;29(5):572-580. doi: 10.1111/acem.14460. Epub 2022 Apr 23.
- Background: PubMed 32336486Kaeppeli T, Rueegg M, Dreher-Hummel T, Brabrand M, Kabell-Nissen S, Carpenter CR, Bingisser R, Nickel CH. Validation of the Clinical Frailty Scale for Prediction of Thirty-Day Mortality in the Emergency Department. Ann Emerg Med. 2020 Sep;76(3):291-300. doi: 10.1016/j.annemergmed.2020.03.028. Epub 2020 Apr 24.
- Background: PubMed 30377439Ozturk E, van Iersel M, Stommel MM, Schoon Y, Ten Broek RR, van Goor H. Small bowel obstruction in the elderly: a plea for comprehensive acute geriatric care. World J Emerg Surg. 2018 Oct 20;13:48. doi: 10.1186/s13017-018-0208-z. eCollection 2018.
- Background: PubMed 31485900Koh A, Adiamah A, Chowdhury A, Mohiuddin MK, Bharathan B. Therapeutic Role of Water-Soluble Contrast Media in Adhesive Small Bowel Obstruction: a Systematic Review and Meta-Analysis. J Gastrointest Surg. 2020 Feb;24(2):473-483. doi: 10.1007/s11605-019-04341-7. Epub 2019 Aug 13.
- Background: PubMed 25421079Springer JE, Bailey JG, Davis PJ, Johnson PM. Management and outcomes of small bowel obstruction in older adult patients: a prospective cohort study. Can J Surg. 2014 Dec;57(6):379-84. doi: 10.1503/cjs.029513.
- Background: PubMed 28728984Hajibandeh S, Hajibandeh S, Panda N, Khan RMA, Bandyopadhyay SK, Dalmia S, Malik S, Huq Z, Mansour M. Operative versus non-operative management of adhesive small bowel obstruction: A systematic review and meta-analysis. Int J Surg. 2017 Sep;45:58-66. doi: 10.1016/j.ijsu.2017.07.073. Epub 2017 Jul 17.
- Background: PubMed 29603126Peacock O, Bassett MG, Kuryba A, Walker K, Davies E, Anderson I, Vohra RS; National Emergency Laparotomy Audit (NELA) Project Team. Thirty-day mortality in patients undergoing laparotomy for small bowel obstruction. Br J Surg. 2018 Jul;105(8):1006-1013. doi: 10.1002/bjs.10812. Epub 2018 Mar 30.
- Background: PubMed 20678892Kuo YW, Yen M, Fetzer S, Lee JD. Reducing the pain of nasogastric tube intubation with nebulized and atomized lidocaine: a systematic review and meta-analysis. J Pain Symptom Manage. 2010 Oct;40(4):613-20. doi: 10.1016/j.jpainsymman.2010.01.025. Epub 2010 Aug 3.
- Background: PubMed 9494307Morrison RS, Ahronheim JC, Morrison GR, Darling E, Baskin SA, Morris J, Choi C, Meier DE. Pain and discomfort associated with common hospital procedures and experiences. J Pain Symptom Manage. 1998 Feb;15(2):91-101.
- Background: PubMed 28912083Berman DJ, Ijaz H, Alkhunaizi M, Kulie PE, Vaziri K, Richards LM, Meltzer AC. Nasogastric decompression not associated with a reduction in surgery or bowel ischemia for acute small bowel obstruction. Am J Emerg Med. 2017 Dec;35(12):1919-1921. doi: 10.1016/j.ajem.2017.08.029. Epub 2017 Aug 15.
- Background: PubMed 9144067Edlich RF, Woods JA. Wangensteen's transformation of the treatment of intestinal obstruction from empiric craft to scientific discipline. J Emerg Med. 1997 Mar-Apr;15(2):235-41. doi: 10.1016/s0736-4679(96)00351-4.
- Individual participant dataSharing planned: Undecided. Limited (providing full anonymization) data may be provided to other researchers
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Daniel B Wilhelms, PhD principal investigator
Linkoeping University
8 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Small Bowel Obstruction and Frailty, run by Daniel Wilhelms at 8 sites in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 14 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 8 sites in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain at Emergency Department discharge (time frame: at Emergency Department Discharge, assessed up to 48 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06262815, which also lists 16 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Apr 2026.