Knee OsteoarthritisNCT06289218
Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis
A study testing interferential current, kinesio taping and exercise in people with Knee Osteoarthritis, run by Cairo University.
Trial summary
The purpose of this study will be to compare the combined effect of using Kinesio taping versus interferential current with an exercise program on knee pain, function, knee range of motion, knee muscle strength, and functional mobility in chronic knee osteoarthritis. Read more about this study
- Who is it for?
- Ages 40 to 65 years
- Conditions the study is for
- Knee Osteoarthritis
- What is being tested?
- interferential current, kinesio taping and exercise
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 63 participants
- Where
- No sites listed yet
- Study dates
- 15 Jul 2025to 21 Sep 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- sixty-three Male and female patients aged between 40 and 65 years old were diagnosed clinically and radiologically as knee osteoarthritis grade mild and moderate chronic knee osteoarthritis.
- BMI ranges between 20 and 32 kg/m2.
- Knee OA grades 1 and 2 are based on Kellgren and Lawrence's grades. Narrowing of joint space, definite osteophytes.
- Unilateral knee osteoarthritis.
- Knee pain for most days of the prior month, in addition to at least 3 of the following:
- Crepitus on active joint motion
Show all 11Show fewer
- Morning stiffness less than 30 minutes duration
- Age older than 50 years
- Bony enlargement of the knee on examination
- Bony tenderness of the knee on examination
- No palpable warmth.
Who cannot join
- Patients having the following conditions will be excluded from the study:
- Comorbidities such as (rheumatoid arthritis, cancer, osteoporosis, and joint infection).
- Previous surgery for knee OA.
- BMI more than 33 kg/m2.
- Suffering from polyarticular disease.
- Severe mechanical deformity (diaphyseal Varus deformity of 4° and valgus of 16°).
- Previous arthroscopy within the last year.
- Systemic autoimmune rheumatoid disease (connective tissue disease and systemic necrotizing vasculitis).
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis: a Comparative Study
The purpose of this study will be to compare the combined effect of using Kinesio taping versus interferential current with an exercise program on knee pain, function, knee range of motion, knee muscle strength, and functional mobility in chronic knee osteoarthritis.
Read the detailed description
Knee osteoarthritis (KOA) is the most common form of degenerative joint disease affecting 15%-40% of people over 40 years of age. In 2020, the global incidence of KOA was 86.7 million individuals. KOA is responsible for substantial health and economic costs. KOA is the most common cause of pain and disability among older persons. The key symptoms of KOA are pain, functional disability, and decreased patient quality of life through its negative effects on mobility, mood, and sleep. Other symptoms are swelling, stiffness, joint deformity, and muscular atrophy.
The Treatment goals for KOA are to decrease pain and improve physical function. Physical therapy decreased pain and functional disability in patients with KOA. The therapeutic techniques include therapeutic exercises, electrotherapy, and manual therapy. Several meta-analysis and systematic reviews have evidence of various types of exercises including aerobic and resistance exercises which is effective in reducing pain and functional disabilities in a patient with KOA especially quadriceps muscle strengthening with open and closed chain training. Specific recommendations including physical activity, reducing body weight, reducing sedentary time, and managing diabetes disease can improve function and symptoms of KOA. To improve the individual's function, and reduce pain and disability, several interventions had been investigated to promote physical activity.
Kinesio taping (KT) is a conservative therapeutic technique used for the treatment of several musculoskeletal disorders which has increased attention from physicians and physiotherapists in recent years. KT, first introduced in 1979 in Japan, is used for the treatment and prevention of several sports injuries and several clinical conditions. In 2011, KT is recommended by the American College of Rheumatology (ACR) for the treatment of patients with knee OA, and it is commonly used to treat knee OA.
Kinesio taping (KT) is an alternative taping technique which is an elastic woven cotton strip with heat-sensitive acrylic adhesive, a high-stretch elastic adhesive material, it is applied directly to the skin and can be left on the skin for several days due to its strong adherence. The application of KT for four weeks can reduce the pain so the patient can reduce the use pain killers. Kinesio taping (KT) is a low-cost, safe, noninvasive, non-pharmacological method, that has minimal side effects and can be a convenient option for the treatment of musculoskeletal disorders such as knee OA.
Interferential current (IFC) is a simple, non-invasive, non-pharmacological, more comfortable treatment used to relieve pain. IFC known as kilohertz-frequency alternating current, which is a pair of signal generators with one fixed frequency of 4000 Hz and the other varying in frequency between 4000 and 4250 Hz. IFC can reduce skin impedance, reach deeper tissue, and can be utilized as an alternative medication or supplement to drugs in treating pain. IFC is the most effective pain relief treatment for the management of KOA.
Exercises play a major role in treating patients with KOA; it can improve both pain and function. Therefore What about comparing the application of kinesio taping combined with exercises versus the IFC therapy combined with exercises in treating patients with KOA?
- Conditions
- Knee Osteoarthritis
- Being tested
- interferential current, kinesio taping, exercise
- Medical subject headings
- Osteoarthritis, Knee
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
interferential currentDevice
Also called IFC
IFC plus exercise
kinesio tapingOther
Also called KT
KT plus exercise
exerciseOther
exercise only
| Study group | Role | What they receive |
|---|---|---|
| interferential current plus exercise | Experimental | interferential current plus exercise group Receives: Device: interferential current |
| kinesio taping plus exercise | Experimental | kinesio taping plus exercise group Receives: Other: kinesio taping |
| Control group | Other | Control group Receives: Other: exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
knee flexion range of motion
to measure Knee joint active range of motion (flexion) by universal goniometer
Measured: pre-intervention and after 4 weeks of treatment
knee extension range of motion
to measure Knee joint active range of motion (extension) by universal goniometer
Measured: pre-intervention and after 4 weeks of treatment
quadriceps muscle strength
to test the isometric quadriceps muscle strength by hand-held dynamometer
Measured: pre-intervention and after 4 weeks of treatment
The Western Ontario and McMaster Universities Osteoarthritis Index
to measure knee function and knee pain degree
Measured: pre-intervention and after 4 weeks of treatment
Timed up and go test
to measure knee function mobility by the Timed up and go test
Measured: pre-intervention and after 4 weeks of treatment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Mar 2024
- Study start15 Jul 2025 (estimated)
- Primary completion21 Sep 2025 (estimated)
- Study completion21 Sep 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (69)Papers the sponsor has linked to this study.
- Other trials for Knee OsteoarthritisStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 63 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Norhan Elsaid Ahmed Elsaid, Cairo University
- Investigators
- Salwa Fadl Abd Elmageed, Prof.Dr, Principal investigator, Professor at Department of Physical Therapy for Musculoskeletal Disorders and Its Surgery
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06289218
- Sponsor's protocol ID
- Treating knee osteoarthritis
- Status last verified
- May 2025
- First submitted
- 18 Feb 2024
- Last updated
- 9 May 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Aaron RK, Ciombor DM. Therapeutic effects of electromagnetic fields in the stimulation of connective tissue repair. J Cell Biochem. 1993 May;52(1):42-6. doi: 10.1002/jcb.240520107.
PubMed 8320274Alqualo-Costa R, Thome GR, Perracini MR, Liebano RE. Low-level laser therapy and interferential current in patients with knee osteoarthritis: a randomized controlled trial protocol. Pain Manag. 2018 May;8(3):157-166. doi: 10.2217/pmt-2017-0057. Epub 2018 May 3.
PubMed 29722602Atamaz FC, Durmaz B, Baydar M, Demircioglu OY, Iyiyapici A, Kuran B, Oncel S, Sendur OF. Comparison of the efficacy of transcutaneous electrical nerve stimulation, interferential currents, and shortwave diathermy in knee osteoarthritis: a double-blind, randomized, controlled, multicenter study. Arch Phys Med Rehabil. 2012 May;93(5):748-56. doi: 10.1016/j.apmr.2011.11.037. Epub 2012 Mar 28.
PubMed 22459699Aw NM, Yeo SJ, Wylde V, Wong SB, Chan D, Thumboo J, Leung YY. Impact of pain sensitisation on the quality of life of patients with knee osteoarthritis. RMD Open. 2022 Mar;8(1):e001938. doi: 10.1136/rmdopen-2021-001938.
PubMed 35296529Beauchet O, Fantino B, Allali G, Muir SW, Montero-Odasso M, Annweiler C. Timed Up and Go test and risk of falls in older adults: a systematic review. J Nutr Health Aging. 2011 Dec;15(10):933-8. doi: 10.1007/s12603-011-0062-0.
PubMed 22159785Brunenberg DE, van Steyn MJ, Sluimer JC, Bekebrede LL, Bulstra SK, Joore MA. Joint recovery programme versus usual care: an economic evaluation of a clinical pathway for joint replacement surgery. Med Care. 2005 Oct;43(10):1018-26. doi: 10.1097/01.mlr.0000178266.75744.35.
PubMed 16166871Cadogan A, Laslett M, Hing W, McNair P, Williams M. Reliability of a new hand-held dynamometer in measuring shoulder range of motion and strength. Man Ther. 2011 Feb;16(1):97-101. doi: 10.1016/j.math.2010.05.005.
PubMed 20621547Celik D, Dirican A, Baltaci G. Intrarater reliability of assessing strength of the shoulder and scapular muscles. J Sport Rehabil. 2012 Feb 29;21(1):1-5. doi: 10.1123/jsr.2012.TR3. Print 2012 Feb 1.
PubMed 22495260Chapple CM, Nicholson H, Baxter GD, Abbott JH. Patient characteristics that predict progression of knee osteoarthritis: a systematic review of prognostic studies. Arthritis Care Res (Hoboken). 2011 Aug;63(8):1115-25. doi: 10.1002/acr.20492.
PubMed 21560257Chen HL, Yang FA, Lee TH, Liou TH, Escorpizo R, Chen HC. Effectiveness of interferential current therapy in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. Sci Rep. 2022 Jun 11;12(1):9694. doi: 10.1038/s41598-022-13478-6.
PubMed 35690604de Paula Gomes CAF, Politti F, de Souza Bacelar Pereira C, da Silva ACB, Dibai-Filho AV, de Oliveira AR, Biasotto-Gonzalez DA. Exercise program combined with electrophysical modalities in subjects with knee osteoarthritis: a randomised, placebo-controlled clinical trial. BMC Musculoskelet Disord. 2020 Apr 20;21(1):258. doi: 10.1186/s12891-020-03293-3.
PubMed 32312265Deyle GD, Allen CS, Allison SC, Gill NW, Hando BR, Petersen EJ, Dusenberry DI, Rhon DI. Physical Therapy versus Glucocorticoid Injection for Osteoarthritis of the Knee. N Engl J Med. 2020 Apr 9;382(15):1420-1429. doi: 10.1056/NEJMoa1905877.
PubMed 32268027Ellison AE, Berg EE. Embryology, anatomy, and function of the anterior cruciate ligament. Orthop Clin North Am. 1985 Jan;16(1):3-14.
PubMed 3969275Escamilla RF, Zheng N, Macleod TD, Edwards WB, Hreljac A, Fleisig GS, Wilk KE, Moorman CT 3rd, Imamura R, Andrews JR. Patellofemoral joint force and stress between a short- and long-step forward lunge. J Orthop Sports Phys Ther. 2008 Nov;38(11):681-90. doi: 10.2519/jospt.2008.2694.
PubMed 18978453Goats GC. Pulsed electromagnetic (short-wave) energy therapy. Br J Sports Med. 1989 Dec;23(4):213-6. doi: 10.1136/bjsm.23.4.213. No abstract available.
PubMed 2629997
Study at a glance
From the registry record, last updated by the sponsor on 9 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis: a Comparative Study
- ClinicalTrials.gov ID
- NCT06289218
- Acronym / sponsor ID
- Treating knee osteoarthritis
- Conditions
- Knee Osteoarthritis
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 63 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 15 Jul 2025 (estimated)
- Primary completion
- 21 Sep 2025 (estimated)
- Study completion
- 21 Sep 2025 (estimated)
- First posted
- 1 Mar 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study will be to compare the combined effect of using Kinesio taping versus interferential current with an exercise program on knee pain, function, knee range of motion, knee muscle strength, and functional mobility in chronic knee osteoarthritis.
Detailed description
Knee osteoarthritis (KOA) is the most common form of degenerative joint disease affecting 15%-40% of people over 40 years of age. In 2020, the global incidence of KOA was 86.7 million individuals. KOA is responsible for substantial health and economic costs. KOA is the most common cause of pain and disability among older persons. The key symptoms of KOA are pain, functional disability, and decreased patient quality of life through its negative effects on mobility, mood, and sleep. Other symptoms are swelling, stiffness, joint deformity, and muscular atrophy.
The Treatment goals for KOA are to decrease pain and improve physical function. Physical therapy decreased pain and functional disability in patients with KOA. The therapeutic techniques include therapeutic exercises, electrotherapy, and manual therapy. Several meta-analysis and systematic reviews have evidence of various types of exercises including aerobic and resistance exercises which is effective in reducing pain and functional disabilities in a patient with KOA especially quadriceps muscle strengthening with open and closed chain training. Specific recommendations including physical activity, reducing body weight, reducing sedentary time, and managing diabetes disease can improve function and symptoms of KOA. To improve the individual's function, and reduce pain and disability, several interventions had been investigated to promote physical activity.
Kinesio taping (KT) is a conservative therapeutic technique used for the treatment of several musculoskeletal disorders which has increased attention from physicians and physiotherapists in recent years. KT, first introduced in 1979 in Japan, is used for the treatment and prevention of several sports injuries and several clinical conditions. In 2011, KT is recommended by the American College of Rheumatology (ACR) for the treatment of patients with knee OA, and it is commonly used to treat knee OA.
Kinesio taping (KT) is an alternative taping technique which is an elastic woven cotton strip with heat-sensitive acrylic adhesive, a high-stretch elastic adhesive material, it is applied directly to the skin and can be left on the skin for several days due to its strong adherence. The application of KT for four weeks can reduce the pain so the patient can reduce the use pain killers. Kinesio taping (KT) is a low-cost, safe, noninvasive, non-pharmacological method, that has minimal side effects and can be a convenient option for the treatment of musculoskeletal disorders such as knee OA.
Interferential current (IFC) is a simple, non-invasive, non-pharmacological, more comfortable treatment used to relieve pain. IFC known as kilohertz-frequency alternating current, which is a pair of signal generators with one fixed frequency of 4000 Hz and the other varying in frequency between 4000 and 4250 Hz. IFC can reduce skin impedance, reach deeper tissue, and can be utilized as an alternative medication or supplement to drugs in treating pain. IFC is the most effective pain relief treatment for the management of KOA.
Exercises play a major role in treating patients with KOA; it can improve both pain and function. Therefore What about comparing the application of kinesio taping combined with exercises versus the IFC therapy combined with exercises in treating patients with KOA?
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| interferential current plus exercise | Experimental | Device: interferential currentinterferential current plus exercise group |
| kinesio taping plus exercise | Experimental | Other: kinesio tapingkinesio taping plus exercise group |
| Control group | Other | Other: exerciseControl group |
Who may qualify
- Ages
- 40 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (11 listed)
- sixty-three Male and female patients aged between 40 and 65 years old were diagnosed clinically and radiologically as knee osteoarthritis grade mild and moderate chronic knee osteoarthritis.
- BMI ranges between 20 and 32 kg/m2.
- Knee OA grades 1 and 2 are based on Kellgren and Lawrence's grades. Narrowing of joint space, definite osteophytes.
- Unilateral knee osteoarthritis.
- Knee pain for most days of the prior month, in addition to at least 3 of the following:
Key exclusion criteria (8 listed)
- Patients having the following conditions will be excluded from the study:
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| interferential currentAlso: IFCIFC plus exercise | Device | interferential current plus exercise |
| kinesio tapingAlso: KTKT plus exercise | Other | kinesio taping plus exercise |
| exerciseexercise only | Other | Control group |
Primary outcome
knee flexion range of motion
Time frame: pre-intervention and after 4 weeks of treatment
to measure Knee joint active range of motion (flexion) by universal goniometer
knee extension range of motion
Time frame: pre-intervention and after 4 weeks of treatment
to measure Knee joint active range of motion (extension) by universal goniometer
quadriceps muscle strength
Time frame: pre-intervention and after 4 weeks of treatment
to test the isometric quadriceps muscle strength by hand-held dynamometer
The Western Ontario and McMaster Universities Osteoarthritis Index
Time frame: pre-intervention and after 4 weeks of treatment
to measure knee function and knee pain degree
Timed up and go test
Time frame: pre-intervention and after 4 weeks of treatment
to measure knee function mobility by the Timed up and go test
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 May 2025.
- Background: PubMed 8320274Aaron RK, Ciombor DM. Therapeutic effects of electromagnetic fields in the stimulation of connective tissue repair. J Cell Biochem. 1993 May;52(1):42-6. doi: 10.1002/jcb.240520107.
- Background: PubMed 29722602Alqualo-Costa R, Thome GR, Perracini MR, Liebano RE. Low-level laser therapy and interferential current in patients with knee osteoarthritis: a randomized controlled trial protocol. Pain Manag. 2018 May;8(3):157-166. doi: 10.2217/pmt-2017-0057. Epub 2018 May 3.
- Background: PubMed 22459699Atamaz FC, Durmaz B, Baydar M, Demircioglu OY, Iyiyapici A, Kuran B, Oncel S, Sendur OF. Comparison of the efficacy of transcutaneous electrical nerve stimulation, interferential currents, and shortwave diathermy in knee osteoarthritis: a double-blind, randomized, controlled, multicenter study. Arch Phys Med Rehabil. 2012 May;93(5):748-56. doi: 10.1016/j.apmr.2011.11.037. Epub 2012 Mar 28.
- Background: PubMed 35296529Aw NM, Yeo SJ, Wylde V, Wong SB, Chan D, Thumboo J, Leung YY. Impact of pain sensitisation on the quality of life of patients with knee osteoarthritis. RMD Open. 2022 Mar;8(1):e001938. doi: 10.1136/rmdopen-2021-001938.
- Background: PubMed 22159785Beauchet O, Fantino B, Allali G, Muir SW, Montero-Odasso M, Annweiler C. Timed Up and Go test and risk of falls in older adults: a systematic review. J Nutr Health Aging. 2011 Dec;15(10):933-8. doi: 10.1007/s12603-011-0062-0.
- Background: PubMed 16166871Brunenberg DE, van Steyn MJ, Sluimer JC, Bekebrede LL, Bulstra SK, Joore MA. Joint recovery programme versus usual care: an economic evaluation of a clinical pathway for joint replacement surgery. Med Care. 2005 Oct;43(10):1018-26. doi: 10.1097/01.mlr.0000178266.75744.35.
- Background: PubMed 20621547Cadogan A, Laslett M, Hing W, McNair P, Williams M. Reliability of a new hand-held dynamometer in measuring shoulder range of motion and strength. Man Ther. 2011 Feb;16(1):97-101. doi: 10.1016/j.math.2010.05.005.
- Background: PubMed 22495260Celik D, Dirican A, Baltaci G. Intrarater reliability of assessing strength of the shoulder and scapular muscles. J Sport Rehabil. 2012 Feb 29;21(1):1-5. doi: 10.1123/jsr.2012.TR3. Print 2012 Feb 1.
- Background: PubMed 21560257Chapple CM, Nicholson H, Baxter GD, Abbott JH. Patient characteristics that predict progression of knee osteoarthritis: a systematic review of prognostic studies. Arthritis Care Res (Hoboken). 2011 Aug;63(8):1115-25. doi: 10.1002/acr.20492.
- Background: PubMed 35690604Chen HL, Yang FA, Lee TH, Liou TH, Escorpizo R, Chen HC. Effectiveness of interferential current therapy in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. Sci Rep. 2022 Jun 11;12(1):9694. doi: 10.1038/s41598-022-13478-6.
- Background: PubMed 32312265de Paula Gomes CAF, Politti F, de Souza Bacelar Pereira C, da Silva ACB, Dibai-Filho AV, de Oliveira AR, Biasotto-Gonzalez DA. Exercise program combined with electrophysical modalities in subjects with knee osteoarthritis: a randomised, placebo-controlled clinical trial. BMC Musculoskelet Disord. 2020 Apr 20;21(1):258. doi: 10.1186/s12891-020-03293-3.
- Background: PubMed 32268027Deyle GD, Allen CS, Allison SC, Gill NW, Hando BR, Petersen EJ, Dusenberry DI, Rhon DI. Physical Therapy versus Glucocorticoid Injection for Osteoarthritis of the Knee. N Engl J Med. 2020 Apr 9;382(15):1420-1429. doi: 10.1056/NEJMoa1905877.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Salwa Fadl Abd Elmageed, Prof.Dr principal investigator
Professor at Department of Physical Therapy for Musculoskeletal Disorders and Its Surgery
Questions about this trial
What is this clinical trial studying?
A study testing interferential current, kinesio taping and exercise in people with Knee Osteoarthritis, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 9 May 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Nourhan Elsaid Ahmed Elsaid (966540792567, nourhanelsaid1993@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
knee flexion range of motion (time frame: pre-intervention and after 4 weeks of treatment). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06289218, which also lists 69 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 May 2025.