Muscle StrengthNCT06321263
Comparison of the Effects of Peripheral Muscle Training and Inspiratory Muscle Training in Geriatric Individuals
A study testing Peripheral Muscle Training and step aerobics training and Inspiratory Muscle Training and step aerobics training in people with Muscle Strength, run by Biruni University at 1 site in Turkey (Türkiye).
Trial summary
In geriatric individuals, there is a decrease in muscle strength, muscle mass and physical performance with ageing. These physiological changes occurring in geriatric individuals make maintaining the physical activity necessary for a healthy life difficult. Read more about this study
- Who is it for?
- Ages 65 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Muscle Strength
- What is being tested?
- Peripheral Muscle Training and step aerobics training and Inspiratory Muscle Training and step aerobics training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 25 Mar 2024to 1 Jun 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 80 years
- All sexes
- Healthy volunteers accepted
- Older adult
Who may be able to join
- 65 years to 80 years (Older ),
- Standardised Mini Mental Test score ≥ 20,
- To walk 10 meters with or without an assistive device,
- If the participants answered No all of the questions of The Physical Activity Readiness Questionnaire
- Volunteering to participate in the study
Who cannot join
- With serious neurological and orthopedic problems that may prevent them from exercising,
- With serious vision and hearing problems,
- With a psychiatric disease,
- With serious cardiac and pulmonary system diseases that may prevent them from exercising,
- With vestibular system problems or medication use that may affect the vestibular system,
- Smokers.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Golden Years Life Center
Çanakkale
Sezen Uyanık, 0 286 21 800 18 ext. 14006, sezen.uyanik@comu.edu.tr
About this study
Official title: Comparison of the Effects of Peripheral Muscle Training and Inspiratory Muscle: Randomized Clinical Study.
In geriatric individuals, there is a decrease in muscle strength, muscle mass and physical performance with ageing. These physiological changes occurring in geriatric individuals make maintaining the physical activity necessary for a healthy life difficult. Weakness of respiratory muscles in geriatric individuals can increase the prevalence of diseases and disability. It has been shown in the literature that peripheral muscle training and inspiratory muscle training increase exercise capacity similarly. The effectiveness of moderate-intensity peripheral muscle training and inspiratory muscle training in sarcopenic geriatric individuals was compared and found to have similar effects on muscle strength.
Our study aims to compare the effects of inspiratory and peripheral muscle training in addition to aerobic exercise on muscle strength, physical performance, respiratory muscle strength, functional capacity, sarcopenia, and quality of life.
Read the detailed description
Aging causes decline in physiological systems, including the cardiorespiratory system, musculo-skeletal system, vestibulo-ocular system, slowed postural control and cognitive function (especially dual task and executive functions). These changes occurring in geriatric individuals are an increased risk factor for various diseases and affect the individual's daily living activities, working life, addiction status and communication with the environment.
The most recommended physical activity subgroups in the guidelines for geriatric individuals are aerobic exercises, strengthening exercises, flexibility exercises and balance exercises. Physiological changes that occur in the organism during the aging process can cause muscle weakness, functional losses/limitations, balance problems, cognitive problems, chronic diseases and mortality. However, physiological and mechanical respiratory changes in geriatric individuals; It is known that there is a decrease in lung elasticity, respiratory muscle strength and chest wall compliance. These physiological changes make it difficult to maintain the physical activity necessary for a healthy life. It has also been shown that weakness of respiratory muscles in geriatric individuals can increase the rate of morbidity and mortality.
It is reported in the literature that respiratory muscle training (RMT) strengthens the diaphragm in geriatric individuals and may have a protective effect against respiratory tract infections by improving aerobic capacity, physical performance and coughing skill. In addition, studies have shown that Inspiratory Muscle Training (IMT) increases the strength of the inspiratory respiratory muscles, allows a more mechanically effective breathing pattern, and provides improvements in exercise capacity, diaphragm thickness and mobility, cardiac autonomic control and functional autonomy. Studies have shown that IMT is effective and applicable in improving balance ability. It has been reported to improve dynamic and reactive balance, as well as gait speed and inspiratory muscle function in healthy geriatric individuals. Considering the stated benefits of IMT, some authors suggest that it is an alternative or complementary training method that can be used for geriatric individuals, especially when other types of exercise are not possible, and that it should be added to rehabilitation programs.
In general, it has been reported in the literature that resistant exercise training is preferred as an intervention in geriatric individuals and that this training improves muscle strength, physical performance and functional performance. In a study where a high-intensity resistance training program was applied in sarcopenic geriatric women, it was reported that it increased respiratory muscle strength and Maximum Expiratory Pressure (MEP) and affected health-related quality of life.
There are opinions reported in the literature that improvement in peripheral and inspiratory muscle strength will reduce the risk of mortality. The effects of moderate-intensity peripheral muscle training and inspiratory muscle training were compared in sarcopenic geriatric individuals and were found to have similar effects on muscle strength. It has been reported that there is no significant change in muscle mass and physical performance. However, no study has been found in which the aerobic and strengthening exercises recommended for geriatric individuals are combined. In order to shed light on this deficiency in the literature, the investigators aim in our study to compare the effects of peripheral muscle training and inspiratory muscle training combined with aerobic training on muscle strength, physical performance, functional capacity and quality of life.
- Conditions
- Muscle Strength
- Being tested
- Peripheral Muscle Training and step aerobics training, Inspiratory Muscle Training and step aerobics training
- Keywords
- Muscle strength, Physical performance, Respiratory muscle strength, Functional capacity, Quality of life
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Peripheral Muscle Training and step aerobics trainingOther
Also called Peripheral Muscle Training
First 5-minute warm-up in the protocol (calisthenic exercises); 30-40 minutes of resistance exercises and step aerobic exercises and the last 5 minutes cooling (stretching exercises) period will be applied.
Inspiratory Muscle Training and step aerobics trainingOther
Also called Inspiratory Muscle Training
First 5-minute warm-up in the protocol (calisthenic exercises); 30-40 minutes of resistance exercises and step aerobic exercises and the last 5 minutes cooling (stretching exercises) period will be applied.
| Study group | Role | What they receive |
|---|---|---|
| Peripheral Muscle Training Group | Experimental | Older individuals in this group will participate in group exercise training, including aerobic and resistance training, twice a week for ten weeks, each session supervised by a researcher physiotherapist and lasting one hour. Receives: Other: Peripheral Muscle Training and step aerobics training |
| Inspiratory Muscle Training Group: | Experimental | Older people in this group will perform aerobic and resistance training for 1 hour a day, twice a week for ten weeks, under the supervision of a researcher physiotherapist. As for Inspiratory Muscle Training, they will participate in training with 30 breathing cycles a day, six days a week, for ten weeks (two days in the clinic, four days at home). Receives: Other: Inspiratory Muscle Training and step aerobics training |
What is being measured
The primary outcome is the main question the study is designed to answer.
The sociodemographic data form
Socio-demographic data of individuals (name-surname, age, gender, height,weight, smoking, occupation, education) will be collected with the demographic data collection form created by the researchers. In the clinical information section, other diseases and medications used will be recorded.
Measured: Ten weeks
Hand grip strength
Three consecutive measurements will be made on the dominant hand with a Jamar hand dynamometer, 1 minute apart, and the highest value will be recorded.
Measured: Ten weeks
Maximal inspiratory and expiratory pressures (MIP, MEP)
Static inspiratory (MIP) or expiratory (MEP) mouth pressures assess respiratory muscle strength.
Measured: Ten weeks
6-Minute Walk Test (6MWT)
The 6MWT will be used to measure functional capacity.
Measured: Ten weeks
The Short Physical Performance Battery (SPPB)
SPPB is a set of tests that combine gait speed, chair stand, and balance measures. It is used to predict possible disability and monitor function in older individuals.
Measured: Ten weeks
Assessment of seniors᾽ quality of life: WHOQOL-OLD questionnaire
WHOQOL-OLD, a 24-item QOL measure, was developed by the WHOQOL Group as an add-on module to their QOL measures, specifically for use with older adults. A total score is the mean of the summed facet scores and ranges from one to five, with higher scores indicating better QOL.
Measured: Ten weeks
Secondary outcomes (1)
SARC-F questionnaire
It is a rapid diagnostic test developed for sarcopenia. A SARC-F survey score ≥ 4 is important for the diagnosis of sarcopenia. SARC-F score range is from 0 to 10; 0-3 points represent healthy condition, 4 points and above represent symptomatic condition.
Measured: Ten weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Mar 2024
- Study start25 Mar 2024
- Primary completion27 Sep 2024
- Study completion1 Jun 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (15)Papers the sponsor has linked to this study.
- Other trials for Muscle StrengthStudies of the same condition, open and under way.
- More trials run by Biruni UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Biruni University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Buket AKINCI, Biruni University
- Investigators
- Buket Akıncı, Ass.Prof., Study director, Biruni UniversitySezen Uyanık, MSc, Principal investigator, Çanakkale Onsekiz Mart University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06321263
- Sponsor's protocol ID
- 798307
- Status last verified
- May 2025
- First submitted
- 14 Mar 2024
- Last updated
- 28 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002 Jul 1;166(1):111-7. doi: 10.1164/ajrccm.166.1.at1102. No abstract available.
PubMed 12091180Ferraro FV, Gavin JP, Wainwright TW, McConnell AK. Comparison of balance changes after inspiratory muscle or Otago exercise training. PLoS One. 2020 Jan 24;15(1):e0227379. doi: 10.1371/journal.pone.0227379. eCollection 2020.
PubMed 31978126Flor-Rufino C, Barrachina-Igual J, Perez-Ros P, Pablos-Monzo A, Martinez-Arnau FM. Resistance training of peripheral muscles benefits respiratory parameters in older women with sarcopenia: Randomized controlled trial. Arch Gerontol Geriatr. 2023 Jan;104:104799. doi: 10.1016/j.archger.2022.104799. Epub 2022 Aug 29.
PubMed 36070636Hallage T, Krause MP, Haile L, Miculis CP, Nagle EF, Reis RS, Da Silva SG. The effects of 12 weeks of step aerobics training on functional fitness of elderly women. J Strength Cond Res. 2010 Aug;24(8):2261-6. doi: 10.1519/JSC.0b013e3181ddacc6.
PubMed 20634751Cebria I Iranzo MA, Balasch-Bernat M, Tortosa-Chulia MA, Balasch-Parisi S. Effects of Resistance Training of Peripheral Muscles Versus Respiratory Muscles in Older Adults With Sarcopenia Who are Institutionalized: A Randomized Controlled Trial. J Aging Phys Act. 2018 Oct 1;26(4):637-646. doi: 10.1123/japa.2017-0268. Epub 2018 Aug 27.
PubMed 29431561Joung HJ, Lee Y. Effect of Creative Dance on Fitness, Functional Balance, and Mobility Control in the Elderly. Gerontology. 2019;65(5):537-546. doi: 10.1159/000499402. Epub 2019 May 3.
PubMed 31055579Kalapotharakos VI, Diamantopoulos K, Tokmakidis SP. Effects of resistance training and detraining on muscle strength and functional performance of older adults aged 80 to 88 years. Aging Clin Exp Res. 2010 Apr;22(2):134-40. doi: 10.1007/BF03324786.
PubMed 20440099Kim SH, Shin MJ, Lee JM, Huh S, Shin YB. Effects of a new respiratory muscle training device in community-dwelling elderly men: an open-label, randomized, non-inferiority trial. BMC Geriatr. 2022 Feb 24;22(1):155. doi: 10.1186/s12877-022-02828-8.
PubMed 35209851Laveneziana P, Albuquerque A, Aliverti A, Babb T, Barreiro E, Dres M, Dube BP, Fauroux B, Gea J, Guenette JA, Hudson AL, Kabitz HJ, Laghi F, Langer D, Luo YM, Neder JA, O'Donnell D, Polkey MI, Rabinovich RA, Rossi A, Series F, Similowski T, Spengler CM, Vogiatzis I, Verges S. ERS statement on respiratory muscle testing at rest and during exercise. Eur Respir J. 2019 Jun 13;53(6):1801214. doi: 10.1183/13993003.01214-2018. Print 2019 Jun.
PubMed 30956204Malmstrom TK, Morley JE. SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. J Am Med Dir Assoc. 2013 Aug;14(8):531-2. doi: 10.1016/j.jamda.2013.05.018. Epub 2013 Jun 25. No abstract available.
PubMed 23810110Power M, Quinn K, Schmidt S; WHOQOL-OLD Group. Development of the WHOQOL-old module. Qual Life Res. 2005 Dec;14(10):2197-214. doi: 10.1007/s11136-005-7380-9.
PubMed 16328900Puthoff ML. Outcome measures in cardiopulmonary physical therapy: short physical performance battery. Cardiopulm Phys Ther J. 2008 Mar;19(1):17-22. No abstract available.
PubMed 20467494Segev-Jacubovski O, Herman T, Yogev-Seligmann G, Mirelman A, Giladi N, Hausdorff JM. The interplay between gait, falls and cognition: can cognitive therapy reduce fall risk? Expert Rev Neurother. 2011 Jul;11(7):1057-75. doi: 10.1586/ern.11.69.
PubMed 21721921Seixas MB, Almeida LB, Trevizan PF, Martinez DG, Laterza MC, Vanderlei LCM, Silva LP. Effects of Inspiratory Muscle Training in Older Adults. Respir Care. 2020 Apr;65(4):535-544. doi: 10.4187/respcare.06945. Epub 2019 Oct 29.
PubMed 31662444Woo J, Leung J, Morley JE. Validating the SARC-F: a suitable community screening tool for sarcopenia? J Am Med Dir Assoc. 2014 Sep;15(9):630-4. doi: 10.1016/j.jamda.2014.04.021. Epub 2014 Jun 16.
PubMed 24947762
Study at a glance
From the registry record, last updated by the sponsor on 28 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effects of Peripheral Muscle Training and Inspiratory Muscle: Randomized Clinical Study.
- ClinicalTrials.gov ID
- NCT06321263
- Acronym / sponsor ID
- 798307
- Conditions
- Muscle Strength
- Keywords
- Muscle strength, Physical performance, Respiratory muscle strength, Functional capacity, Quality of life
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Biruni UniversityUniversity, hospital or other
- Study start
- 25 Mar 2024 (actual)
- Primary completion
- 27 Sep 2024 (actual)
- Study completion
- 1 Jun 2025 (estimated)
- First posted
- 20 Mar 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In geriatric individuals, there is a decrease in muscle strength, muscle mass and physical performance with ageing. These physiological changes occurring in geriatric individuals make maintaining the physical activity necessary for a healthy life difficult. Weakness of respiratory muscles in geriatric individuals can increase the prevalence of diseases and disability. It has been shown in the literature that peripheral muscle training and inspiratory muscle training increase exercise capacity similarly. The effectiveness of moderate-intensity peripheral muscle training and inspiratory muscle training in sarcopenic geriatric individuals was compared and found to have similar effects on muscle strength.
Our study aims to compare the effects of inspiratory and peripheral muscle training in addition to aerobic exercise on muscle strength, physical performance, respiratory muscle strength, functional capacity, sarcopenia, and quality of life.
Detailed description
Aging causes decline in physiological systems, including the cardiorespiratory system, musculo-skeletal system, vestibulo-ocular system, slowed postural control and cognitive function (especially dual task and executive functions). These changes occurring in geriatric individuals are an increased risk factor for various diseases and affect the individual's daily living activities, working life, addiction status and communication with the environment.
The most recommended physical activity subgroups in the guidelines for geriatric individuals are aerobic exercises, strengthening exercises, flexibility exercises and balance exercises. Physiological changes that occur in the organism during the aging process can cause muscle weakness, functional losses/limitations, balance problems, cognitive problems, chronic diseases and mortality. However, physiological and mechanical respiratory changes in geriatric individuals; It is known that there is a decrease in lung elasticity, respiratory muscle strength and chest wall compliance. These physiological changes make it difficult to maintain the physical activity necessary for a healthy life. It has also been shown that weakness of respiratory muscles in geriatric individuals can increase the rate of morbidity and mortality.
It is reported in the literature that respiratory muscle training (RMT) strengthens the diaphragm in geriatric individuals and may have a protective effect against respiratory tract infections by improving aerobic capacity, physical performance and coughing skill. In addition, studies have shown that Inspiratory Muscle Training (IMT) increases the strength of the inspiratory respiratory muscles, allows a more mechanically effective breathing pattern, and provides improvements in exercise capacity, diaphragm thickness and mobility, cardiac autonomic control and functional autonomy. Studies have shown that IMT is effective and applicable in improving balance ability. It has been reported to improve dynamic and reactive balance, as well as gait speed and inspiratory muscle function in healthy geriatric individuals. Considering the stated benefits of IMT, some authors suggest that it is an alternative or complementary training method that can be used for geriatric individuals, especially when other types of exercise are not possible, and that it should be added to rehabilitation programs.
In general, it has been reported in the literature that resistant exercise training is preferred as an intervention in geriatric individuals and that this training improves muscle strength, physical performance and functional performance. In a study where a high-intensity resistance training program was applied in sarcopenic geriatric women, it was reported that it increased respiratory muscle strength and Maximum Expiratory Pressure (MEP) and affected health-related quality of life.
There are opinions reported in the literature that improvement in peripheral and inspiratory muscle strength will reduce the risk of mortality. The effects of moderate-intensity peripheral muscle training and inspiratory muscle training were compared in sarcopenic geriatric individuals and were found to have similar effects on muscle strength. It has been reported that there is no significant change in muscle mass and physical performance. However, no study has been found in which the aerobic and strengthening exercises recommended for geriatric individuals are combined. In order to shed light on this deficiency in the literature, the investigators aim in our study to compare the effects of peripheral muscle training and inspiratory muscle training combined with aerobic training on muscle strength, physical performance, functional capacity and quality of life.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Peripheral Muscle Training Group | Experimental | Other: Peripheral Muscle Training and step aerobics trainingOlder individuals in this group will participate in group exercise training, including aerobic and resistance training, twice a week for ten weeks, each session supervised by a researcher physiotherapist and lasting one hour. |
| Inspiratory Muscle Training Group: | Experimental | Other: Inspiratory Muscle Training and step aerobics trainingOlder people in this group will perform aerobic and resistance training for 1 hour a day, twice a week for ten weeks, under the supervision of a researcher physiotherapist. As for Inspiratory Muscle Training, they will participate in training with 30 breathing cycles a day, six days a week, for ten weeks (two days in the clinic, four days at home). |
Who may qualify
- Ages
- 65 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
Key inclusion criteria (5 listed)
- 65 years to 80 years (Older ),
- Standardised Mini Mental Test score ≥ 20,
- To walk 10 meters with or without an assistive device,
- If the participants answered No all of the questions of The Physical Activity Readiness Questionnaire
- Volunteering to participate in the study
Key exclusion criteria (6 listed)
- With serious neurological and orthopedic problems that may prevent them from exercising,
- With serious vision and hearing problems,
- With a psychiatric disease,
- With serious cardiac and pulmonary system diseases that may prevent them from exercising,
- With vestibular system problems or medication use that may affect the vestibular system,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Peripheral Muscle Training and step aerobics trainingAlso: Peripheral Muscle TrainingFirst 5-minute warm-up in the protocol (calisthenic exercises); 30-40 minutes of resistance exercises and step aerobic exercises and the last 5 minutes cooling (stretching exercises) period will be applied. | Other | Peripheral Muscle Training Group |
| Inspiratory Muscle Training and step aerobics trainingAlso: Inspiratory Muscle TrainingFirst 5-minute warm-up in the protocol (calisthenic exercises); 30-40 minutes of resistance exercises and step aerobic exercises and the last 5 minutes cooling (stretching exercises) period will be applied. | Other | Inspiratory Muscle Training Group: |
Primary outcome
The sociodemographic data form
Time frame: Ten weeks
Socio-demographic data of individuals (name-surname, age, gender, height,weight, smoking, occupation, education) will be collected with the demographic data collection form created by the researchers. In the clinical information section, other diseases and medications used will be recorded.
Hand grip strength
Time frame: Ten weeks
Three consecutive measurements will be made on the dominant hand with a Jamar hand dynamometer, 1 minute apart, and the highest value will be recorded.
Maximal inspiratory and expiratory pressures (MIP, MEP)
Time frame: Ten weeks
Static inspiratory (MIP) or expiratory (MEP) mouth pressures assess respiratory muscle strength.
6-Minute Walk Test (6MWT)
Time frame: Ten weeks
The 6MWT will be used to measure functional capacity.
The Short Physical Performance Battery (SPPB)
Time frame: Ten weeks
SPPB is a set of tests that combine gait speed, chair stand, and balance measures. It is used to predict possible disability and monitor function in older individuals.
Assessment of seniors᾽ quality of life: WHOQOL-OLD questionnaire
Time frame: Ten weeks
WHOQOL-OLD, a 24-item QOL measure, was developed by the WHOQOL Group as an add-on module to their QOL measures, specifically for use with older adults. A total score is the mean of the summed facet scores and ranges from one to five, with higher scores indicating better QOL.
1 secondary outcome
SARC-F questionnaire
Time frame: Ten weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 May 2025.
- Background: PubMed 12091180ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002 Jul 1;166(1):111-7. doi: 10.1164/ajrccm.166.1.at1102. No abstract available.
- Background: PubMed 31978126Ferraro FV, Gavin JP, Wainwright TW, McConnell AK. Comparison of balance changes after inspiratory muscle or Otago exercise training. PLoS One. 2020 Jan 24;15(1):e0227379. doi: 10.1371/journal.pone.0227379. eCollection 2020.
- Background: PubMed 36070636Flor-Rufino C, Barrachina-Igual J, Perez-Ros P, Pablos-Monzo A, Martinez-Arnau FM. Resistance training of peripheral muscles benefits respiratory parameters in older women with sarcopenia: Randomized controlled trial. Arch Gerontol Geriatr. 2023 Jan;104:104799. doi: 10.1016/j.archger.2022.104799. Epub 2022 Aug 29.
- Background: PubMed 20634751Hallage T, Krause MP, Haile L, Miculis CP, Nagle EF, Reis RS, Da Silva SG. The effects of 12 weeks of step aerobics training on functional fitness of elderly women. J Strength Cond Res. 2010 Aug;24(8):2261-6. doi: 10.1519/JSC.0b013e3181ddacc6.
- Background: PubMed 29431561Cebria I Iranzo MA, Balasch-Bernat M, Tortosa-Chulia MA, Balasch-Parisi S. Effects of Resistance Training of Peripheral Muscles Versus Respiratory Muscles in Older Adults With Sarcopenia Who are Institutionalized: A Randomized Controlled Trial. J Aging Phys Act. 2018 Oct 1;26(4):637-646. doi: 10.1123/japa.2017-0268. Epub 2018 Aug 27.
- Background: PubMed 31055579Joung HJ, Lee Y. Effect of Creative Dance on Fitness, Functional Balance, and Mobility Control in the Elderly. Gerontology. 2019;65(5):537-546. doi: 10.1159/000499402. Epub 2019 May 3.
- Background: PubMed 20440099Kalapotharakos VI, Diamantopoulos K, Tokmakidis SP. Effects of resistance training and detraining on muscle strength and functional performance of older adults aged 80 to 88 years. Aging Clin Exp Res. 2010 Apr;22(2):134-40. doi: 10.1007/BF03324786.
- Background: PubMed 35209851Kim SH, Shin MJ, Lee JM, Huh S, Shin YB. Effects of a new respiratory muscle training device in community-dwelling elderly men: an open-label, randomized, non-inferiority trial. BMC Geriatr. 2022 Feb 24;22(1):155. doi: 10.1186/s12877-022-02828-8.
- Background: PubMed 30956204Laveneziana P, Albuquerque A, Aliverti A, Babb T, Barreiro E, Dres M, Dube BP, Fauroux B, Gea J, Guenette JA, Hudson AL, Kabitz HJ, Laghi F, Langer D, Luo YM, Neder JA, O'Donnell D, Polkey MI, Rabinovich RA, Rossi A, Series F, Similowski T, Spengler CM, Vogiatzis I, Verges S. ERS statement on respiratory muscle testing at rest and during exercise. Eur Respir J. 2019 Jun 13;53(6):1801214. doi: 10.1183/13993003.01214-2018. Print 2019 Jun.
- Background: PubMed 23810110Malmstrom TK, Morley JE. SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. J Am Med Dir Assoc. 2013 Aug;14(8):531-2. doi: 10.1016/j.jamda.2013.05.018. Epub 2013 Jun 25. No abstract available.
- Background: PubMed 16328900Power M, Quinn K, Schmidt S; WHOQOL-OLD Group. Development of the WHOQOL-old module. Qual Life Res. 2005 Dec;14(10):2197-214. doi: 10.1007/s11136-005-7380-9.
- Background: PubMed 20467494Puthoff ML. Outcome measures in cardiopulmonary physical therapy: short physical performance battery. Cardiopulm Phys Ther J. 2008 Mar;19(1):17-22. No abstract available.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Buket Akıncı, Ass.Prof. study director
Biruni University
Sezen Uyanık, MSc principal investigator
Çanakkale Onsekiz Mart University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Peripheral Muscle Training and step aerobics training and Inspiratory Muscle Training and step aerobics training in people with Muscle Strength, run by Biruni University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Buket Akıncı, Ass.Prof. (902124448276, bakinci@biruni.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The sociodemographic data form (time frame: Ten weeks). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06321263, which also lists 15 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 May 2025.