Knee OsteoarthritisNCT06339944
Effects of Sensory Motor Training and Kinesthetic Exercises in Knee Osteoarthritis.
A study testing sensory motor training and kinesthetic exercises in people with Knee Osteoarthritis, run by Riphah International University at 1 site in Pakistan.
Trial summary
In this study i will see the effects of kinesthetic exercises and sensory motor training on pain and range of motion in patients with knee OA. Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Knee Osteoarthritis
- What is being tested?
- sensory motor training and kinesthetic exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 sitePakistan
- Study dates
- 23 Nov 2023to 1 Jun 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- patients having osteophytes and definite joint space reduction confirmed by radiographs
- Patients having age 40-60 years or both gender are included
Who cannot join
- Rheumatoid arthritis. Hip or ankle instability Hip or knee replacement Unresolved balance disorder Patients with active synovitis
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Sensory Motor Training Versus Kinesthetic Exercises on Pain, Range of Motion, Proprioception and Quality of Life in Knee Osteoarthritis .
In this study i will see the effects of kinesthetic exercises and sensory motor training on pain and range of motion in patients with knee OA.
Read the detailed description
In 2022 a A Pilot Randomized Trial of Different Weekly Applications of Kinesthesia, Balance and Agility Exercise Program for Individuals with Knee Osteoarthritis was conducted.In 2023 A critically appraised research was conducted on Sensorimotor or Balance Training to Increase Knee-Extensor and Knee-Flexor Maximal Strength in Patients With Knee Osteoarthritis.
In past there is no study that compares the effects of SMT and kinesthetic exercises in knee OA.
- Conditions
- Knee Osteoarthritis
- Being tested
- sensory motor training, kinesthetic exercises
- Keywords
- osteoarthritis, pain, SMT
- Medical subject headings
- Osteoarthritis, Knee, Osteoarthritis, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
sensory motor trainingOther
Also called conventional therapy
in this group 17 participants will receive conventional therapy and then followed by kinesthetic exercises. 3 sessions per week includes 10 repetitions with 3sets.
kinesthetic exercisesOther
Also called conventional therapy
in this group 17 participants will receive conventional therapy and then followed by kinesthetic exercises. 3 sessions per week includes 10 repetitions with 3sets.
| Study group | Role | What they receive |
|---|---|---|
| sensory motor training along with conventional therapy. | Experimental | This group will receive sensory motor training exercises after the conventional therapy.
The participants who will be allocated to the SMT group received the same warm-up and stretching program as the CT group, with the same duration and frequency of treatment, but with replacement of the strengthening program with a program emphasizing agility, coordination and balance. Receives: Other: sensory motor training |
| kinesthetic exercises along with conventional therapy. | Active comparator | Group will receive kinesthetic balance exercises after the conventional therapy. All agility-based exercises will be conducted before progressing to balance exercises. For the balance exercises, the participants performed static and dynamic balance exercises with eyes open and then closed by standing on a hard surface and then standing on a soft surface. Receives: Other: kinesthetic exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
VAS
The visual analog scale for pain is a straight line with one end meaning no pain and the other end meaning the worst pain imaginable. A patient marks a point on the line that matches the amount of pain he or she feels.
Measured: 6th week
Secondary outcomes (3)
goniometer
a device that measures an angle or permits the rotation of an object to a definite position
Measured: 6th week
WOMAC questionaire
Western Ontario and McMaster Universities (WOMAC) Osteoarthritis index is a multidimensional self-reported disease-specific questionnaire that assesses pain, stiffness and physical disability in patients with Osteoarthritis (OA) of the knee joint. The Swedish version of WOMAC is a reliable, valid, and responsive instrument with metric properties in agreement with the original widely used version.(16
Measured: 6th week
joint position sense test
Joint position sense is one of the most commonly used measures of proprioception.
Determining JPS involves measuring the accuracy of joint-angle The joint position reproduction test for JPS using goniometry demonstrated moderate to good test-retest reliability and acceptable measurement error in healthy adults.replication,which can be conducted actively or passively and in an open or closed chain environment.
Measured: 6th week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Apr 2024
- Study start23 Nov 2023
- Primary completion1 Jun 2024
- Study completion1 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Knee OsteoarthritisStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 34 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Muhammad Sanaullah, MS, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06339944
- Sponsor's protocol ID
- REC/RCR& AHS/23/0198RubabTalib
- Status last verified
- Aug 2024
- First submitted
- 25 Mar 2024
- Last updated
- 29 Aug 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
UzunkulaoGlu A, KerIm D, Ay S, ErgIn S. Effects of Single-Task Versus Dual-Task Training on Balance Performance in Elderly Patients With Knee Osteoarthritis. Arch Rheumatol. 2019 Apr 26;35(1):35-40. doi: 10.5606/ArchRheumatol.2020.7174. eCollection 2020 Mar.
PubMed 32637918Kus G, Tarakci E, Razak Ozdincler A, Ercin E. Sensory-motor training versus resistance training in the treatment of knee osteoarthritis: A randomized controlled trial. Clin Rehabil. 2023 May;37(5):636-650. doi: 10.1177/02692155221137642. Epub 2022 Nov 12.
PubMed 36373731Gomiero AB, Kayo A, Abraao M, Peccin MS, Grande AJ, Trevisani VF. Sensory-motor training versus resistance training among patients with knee osteoarthritis: randomized single-blind controlled trial. Sao Paulo Med J. 2018 Jan-Feb;136(1):44-50. doi: 10.1590/1516-3180.2017.0174100917. Epub 2017 Dec 7.
PubMed 29236934
Study at a glance
From the registry record, last updated by the sponsor on 29 Aug 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Sensory Motor Training Versus Kinesthetic Exercises on Pain, Range of Motion, Proprioception and Quality of Life in Knee Osteoarthritis .
- ClinicalTrials.gov ID
- NCT06339944
- Acronym / sponsor ID
- REC/RCR& AHS/23/0198RubabTalib
- Conditions
- Knee Osteoarthritis
- Keywords
- osteoarthritis, pain, SMT
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 34 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 23 Nov 2023 (actual)
- Primary completion
- 1 Jun 2024 (actual)
- Study completion
- 1 Jun 2024 (actual)
- First posted
- 1 Apr 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In this study i will see the effects of kinesthetic exercises and sensory motor training on pain and range of motion in patients with knee OA.
Detailed description
In 2022 a A Pilot Randomized Trial of Different Weekly Applications of Kinesthesia, Balance and Agility Exercise Program for Individuals with Knee Osteoarthritis was conducted.In 2023 A critically appraised research was conducted on Sensorimotor or Balance Training to Increase Knee-Extensor and Knee-Flexor Maximal Strength in Patients With Knee Osteoarthritis.
In past there is no study that compares the effects of SMT and kinesthetic exercises in knee OA.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| sensory motor training along with conventional therapy. | Experimental | Other: sensory motor trainingThis group will receive sensory motor training exercises after the conventional therapy. The participants who will be allocated to the SMT group received the same warm-up and stretching program as the CT group, with the same duration and frequency of treatment, but with replacement of the strengthening program with a program emphasizing agility, coordination and balance. |
| kinesthetic exercises along with conventional therapy. | Active comparator | Other: kinesthetic exercisesGroup will receive kinesthetic balance exercises after the conventional therapy. All agility-based exercises will be conducted before progressing to balance exercises. For the balance exercises, the participants performed static and dynamic balance exercises with eyes open and then closed by standing on a hard surface and then standing on a soft surface. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- patients having osteophytes and definite joint space reduction confirmed by radiographs
- Patients having age 40-60 years or both gender are included
Key exclusion criteria (1 listed)
- Rheumatoid arthritis. Hip or ankle instability Hip or knee replacement Unresolved balance disorder Patients with active synovitis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| sensory motor trainingAlso: conventional therapyin this group 17 participants will receive conventional therapy and then followed by kinesthetic exercises. 3 sessions per week includes 10 repetitions with 3sets. | Other | sensory motor training along with conventional therapy. |
| kinesthetic exercisesAlso: conventional therapyin this group 17 participants will receive conventional therapy and then followed by kinesthetic exercises. 3 sessions per week includes 10 repetitions with 3sets. | Other | kinesthetic exercises along with conventional therapy. |
Primary outcome
VAS
Time frame: 6th week
The visual analog scale for pain is a straight line with one end meaning no pain and the other end meaning the worst pain imaginable. A patient marks a point on the line that matches the amount of pain he or she feels.
3 secondary outcomes
goniometer
Time frame: 6th week
WOMAC questionaire
Time frame: 6th week
joint position sense test
Time frame: 6th week
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Aug 2024.
- Background: PubMed 32637918UzunkulaoGlu A, KerIm D, Ay S, ErgIn S. Effects of Single-Task Versus Dual-Task Training on Balance Performance in Elderly Patients With Knee Osteoarthritis. Arch Rheumatol. 2019 Apr 26;35(1):35-40. doi: 10.5606/ArchRheumatol.2020.7174. eCollection 2020 Mar.
- Background: PubMed 36373731Kus G, Tarakci E, Razak Ozdincler A, Ercin E. Sensory-motor training versus resistance training in the treatment of knee osteoarthritis: A randomized controlled trial. Clin Rehabil. 2023 May;37(5):636-650. doi: 10.1177/02692155221137642. Epub 2022 Nov 12.
- Background: PubMed 29236934Gomiero AB, Kayo A, Abraao M, Peccin MS, Grande AJ, Trevisani VF. Sensory-motor training versus resistance training among patients with knee osteoarthritis: randomized single-blind controlled trial. Sao Paulo Med J. 2018 Jan-Feb;136(1):44-50. doi: 10.1590/1516-3180.2017.0174100917. Epub 2017 Dec 7.
- Individual participant dataSharing planned: No
Related trials for Knee Osteoarthritis
Not yet recruiting
Holistic Healing for Knee Osteoarthritis
Knee Osteoarthritis (Knee OA)
Recruiting
Effect of Anti-inflammatory Diet in Osteoarthritis
Osteoarthritis, Knee
Active, not recruitingPhase 2/3
Single vs Triple Hyaluronic Acid in Knee Osteoarthritis
Osteoarthritis, Knee
Not yet recruiting
The Feasibility of a Virtual/Home-based OA Treatment Program in Older Adults With OA and Multimorbidity
Osteoarthritis of the Knee
RecruitingObservational study
Exploring Factors Linked to Worsening Over Time in People With Early-stage Knee Osteoarthritis and Those With Prior Proven Acute Knee Injury.
Knee Osteoarthritis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Muhammad Sanaullah, MS principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing sensory motor training and kinesthetic exercises in people with Knee Osteoarthritis, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Aug 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
VAS (time frame: 6th week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06339944, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Aug 2024.