Mild Cognitive ImpairmentNCT06367231
SCGs as a Proxy for Determining the Cognitive Status of Older Adults
An observational study of Mild Cognitive Impairment and Dementia, run by University of Alberta at 8 sites in Canada.
Trial summary
Detecting memory problems early is crucial for treating conditions like Mild Cognitive Impairment (MCI), which often leads to dementia. Currently, doctors use tests in clinics to check for these issues. However, there's a growing need for better methods to monitor our cognitive skills over time. Read more about this study
- Who is it for?
- Ages 65 years and olderHealthy volunteers can take part
- Conditions the study is for
- Mild Cognitive Impairment, Dementia, Alzheimer Disease
- What is being tested?
- VibrantMinds
- How many people
- 6 participants
- Where
- 8 sitesCanada
- Study dates
- 1 May 2024to 1 May 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- Healthy volunteers accepted
- Older adult
Study population: Older healthy adults (cognitively intact) Older adults with Mild Cognitive Impairment Older adults with Dementia
Who may be able to join
- Reside in Calgary and/or Edmonton, Alberta, Canada
- sufficient English language skills to converse in English with research staff
Who cannot join
- Moderate or severe limitations in the control or movement of the upper extremity (e.g., severe arthritis, amyotrophic lateral sclerosis, multiple sclerosis)
- Visual and hearing impairments
- Attention deficit
Trial locations and contacts
8 sites in 1 country.
8 sites in 1 country
Canada8 sites
Alzheimer Society of Alberta and Northwest Territories
Edmonton, Alberta, T6H 2J3
CapitalCare Corporate Services
Edmonton, Alberta
Edmonton Life Long Learners
Edmonton, Alberta
Institute for Continuing Care Education and Research
Edmonton, Alberta
Shepherd's Care Foundation
Edmonton, Alberta
St. Michael's Long Term Care Centre,
Edmonton, Alberta
Sherwood Care
Sherwood Park, Alberta
Tofield Health Centre
Tofield, Alberta
About this study
Official title: Serious Computer Games as a Proxy for Determining the Cognitive Status of Older Adults
Detecting memory problems early is crucial for treating conditions like Mild Cognitive Impairment (MCI), which often leads to dementia. Currently, doctors use tests in clinics to check for these issues. However, there's a growing need for better methods to monitor our cognitive skills over time. Computer games emerge as a cost-effective solution for assessing the brain functions of older adults.
In our study, we are investigating the potential of computer games to reflect the cognitive skills of older adults. We developed the VibrantMinds platform, featuring five games: Whack-a-Mole, Bejeweled, Mahjong Solitaire, Word Search, and Memory Game. We have evaluated these games for ease of use, enjoyment, and their impact on brain functions. Now, our goal is to determine whether these games can offer valuable insights into the cognitive skills of older adults.
We are collecting demographic data, game-playing data, and cognitive test results. Our analysis will determine the correlation between game data, cognitive test outcomes, and demographic information. Additionally, we will assess both the perceived and observed engagement of older adults as they play the games.
- Being tested
- VibrantMinds
- Keywords
- Serious computer game, computer games, VibrantMinds
- Medical subject headings
- Cognitive Dysfunction, Dementia, Alzheimer Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
VibrantMindsOther
Also called Serious Computer Games
We are exploring the potential of computer games to reveal insights into the cognitive abilities of older adults. We developed the VibrantMinds (https://vibrant-minds.org/vibrantminds2/start) platform, featuring five games: Whack-a-Mole, Bejeweled, Mahjong Solitaire, Word Search, and Memory Game. Our evaluation focused on the usability of these games, their appeal to users, and their effectiveness in enhancing cognitive functions. The next phase of our study aims to determine whether these games can offer meaningful data on the cognitive skills of older adults.
| Study group | Role | What they receive |
|---|---|---|
| Serious Computer Game Intervention | Older Adults (healthy), Older adults with MCI, older adults with dementia
Each participant will undergo three sessions, spaced one week apart. These sessions will take place either at locations that support the research team's activities or at the participants' homes, offering flexibility to accommodate individual circumstances. The format of these sessions can vary, being either group-based or individual.
Each session is designed to last approximately one hour, with a maximum duration of 90 minutes to ensure thoroughness without overwhelming participants. Receives: Other: VibrantMinds |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cognition - Global
The Montreal Cognitive Assessment (MoCA) is a brief 30-point test used to screen for cognitive dysfunction in areas including memory, language, visuospatial skills, executive functions, attention, concentration, and orientation. A score of 26 or above is considered normal. Lower scores suggest potential cognitive impairment.
Measured: At each session (3 sessions total, once per week, one week apart)
Secondary outcomes (4)
Cognition - Global
The Mini-Mental State Examination (MMSE) is a widely used 30-point questionnaire that assesses cognitive function, including orientation, recall, attention, calculation, language, and basic motor skills. A score of 24 or above typically indicates normal cognitive function, while lower scores suggest possible impairment.
Measured: At each session (3 sessions total, once per week, one week apart)
Cognition - Executive Function
Trail Making Test, Part A and B. The norms and average completion times for the Trail Making Test (TMT) Parts A and B can vary significantly based on age, education, and the specific population being tested. However, general guidelines can provide some insight:
TMT Part A: Average completion times for adults can range from 20 to 40 seconds. Younger adults and those with higher levels of education tend to complete Part A more quickly. Completion times increase with age.
TMT Part B: This part is more complex and typically takes longer to complete, with average times ranging from 50 to 120 seconds.
Measured: At each session (3 sessions total, once per week, one week apart)
Game Performance
Level, Accuracy, Time
Measured: Obtained during each game (game played at each session, once per week, one week apart)
Game Engagement
Self-reported questionnaire of engagement and engagement indicators
Measured: At each session (3 sessions total, once per week, one week apart)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Apr 2024
- Study start1 May 2024
- Primary completion1 May 2025
- Study completion1 May 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Mild Cognitive ImpairmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 6 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Alberta
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06367231
- Sponsor's protocol ID
- Pro00134554
- Status last verified
- Aug 2025
- First submitted
- 23 Mar 2024
- Last updated
- 8 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Serious Computer Games as a Proxy for Determining the Cognitive Status of Older Adults
- ClinicalTrials.gov ID
- NCT06367231
- Acronym / sponsor ID
- Pro00134554
- Keywords
- Serious computer game, computer games, VibrantMinds
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 6 participants (actual)
- Lead sponsor
- University of AlbertaUniversity, hospital or other
- Study start
- 1 May 2024 (actual)
- Primary completion
- 1 May 2025 (actual)
- Study completion
- 1 May 2025 (actual)
- First posted
- 16 Apr 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Detecting memory problems early is crucial for treating conditions like Mild Cognitive Impairment (MCI), which often leads to dementia. Currently, doctors use tests in clinics to check for these issues. However, there's a growing need for better methods to monitor our cognitive skills over time. Computer games emerge as a cost-effective solution for assessing the brain functions of older adults.
In our study, we are investigating the potential of computer games to reflect the cognitive skills of older adults. We developed the VibrantMinds platform, featuring five games: Whack-a-Mole, Bejeweled, Mahjong Solitaire, Word Search, and Memory Game. We have evaluated these games for ease of use, enjoyment, and their impact on brain functions. Now, our goal is to determine whether these games can offer valuable insights into the cognitive skills of older adults.
We are collecting demographic data, game-playing data, and cognitive test results. Our analysis will determine the correlation between game data, cognitive test outcomes, and demographic information. Additionally, we will assess both the perceived and observed engagement of older adults as they play the games.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Serious Computer Game Intervention | – | Other: VibrantMindsOlder Adults (healthy), Older adults with MCI, older adults with dementia Each participant will undergo three sessions, spaced one week apart. These sessions will take place either at locations that support the research team's activities or at the participants' homes, offering flexibility to accommodate individual circumstances. The format of these sessions can vary, being either group-based or individual. Each session is designed to last approximately one hour, with a maximum duration of 90 minutes to ensure thoroughness without overwhelming participants. |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
- Study population
- Older healthy adults (cognitively intact) Older adults with Mild Cognitive Impairment Older adults with Dementia
Key inclusion criteria (2 listed)
- Reside in Calgary and/or Edmonton, Alberta, Canada
- sufficient English language skills to converse in English with research staff
Key exclusion criteria (3 listed)
- Moderate or severe limitations in the control or movement of the upper extremity (e.g., severe arthritis, amyotrophic lateral sclerosis, multiple sclerosis)
- Visual and hearing impairments
- Attention deficit
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| VibrantMindsAlso: Serious Computer GamesWe are exploring the potential of computer games to reveal insights into the cognitive abilities of older adults. We developed the VibrantMinds (https://vibrant-minds.org/vibrantminds2/start) platform, featuring five games: Whack-a-Mole, Bejeweled, Mahjong Solitaire, Word Search, and Memory Game. Our evaluation focused on the usability of these games, their appeal to users, and their effectiveness in enhancing cognitive functions. The next phase of our study aims to determine whether these games can offer meaningful data on the cognitive skills of older adults. | Other | Serious Computer Game Intervention |
Primary outcome
Cognition - Global
Time frame: At each session (3 sessions total, once per week, one week apart)
The Montreal Cognitive Assessment (MoCA) is a brief 30-point test used to screen for cognitive dysfunction in areas including memory, language, visuospatial skills, executive functions, attention, concentration, and orientation. A score of 26 or above is considered normal. Lower scores suggest potential cognitive impairment.
4 secondary outcomes
Cognition - Global
Time frame: At each session (3 sessions total, once per week, one week apart)
Cognition - Executive Function
Time frame: At each session (3 sessions total, once per week, one week apart)
Game Performance
Time frame: Obtained during each game (game played at each session, once per week, one week apart)
Game Engagement
Time frame: At each session (3 sessions total, once per week, one week apart)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Aug 2025.
- VibrantMinds PlatformLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
8 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Mild Cognitive Impairment and Dementia, run by University of Alberta at 8 sites in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 8 sites in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cognition - Global (time frame: At each session (3 sessions total, once per week, one week apart)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Aug 2025.