Clinical trials: Healthy Aging
Healthy Aging
Effect of Vestibular Perceptual Learning on Vestibular Thresholds and Balance
The intervention being studied is a minimal risk perceptual learning protocol delivered in an academic laboratory setting; the goal of the intervention is to improve the perception of passive whole-body tilts and/or translations…
- Trial name
- NCT05818787
- Testing
- Roll Tilt Training, Translation Training, Both Tilt and Translation Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Healthy Aging
Effects of Astaxanthin Supplementation on Metabolism, Cognition, and Physical Function in Older Adults
This study evaluated whether astaxanthin supplementation affects the body's ability to use fat for energy, cognitive performance, and physical function in healthy older adults.
- Trial name
- NCT07876193
- Testing
- Astaxanthin Oral Capsule
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Alabama
Healthy Volunteers, Aging, Healthy
Intervention Program for Psychological Well-Being in Institutionalized Older Adults Through Virtual Reality
This randomized controlled trial (N = 60) evaluates the acceptability and efficacy of an immersive virtual reality (IVR) intervention designed to enhance psychological well-being in older adults without cognitive impairment…
- Trial name
- RRCE (NCT07884435)
- Testing
- Active IVR Group, Passive IVR Goup
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Francisco Antonio Nieto Escámez
Skin Ageing, Healthy Ageing
Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age
This study evaluated the effects of a daily oral supplement regimen (Advanced ID Brain, Heart and Eye Omega Gel Capsules taken with Advanced ID Longevity and Collagen Complex Powder) on measures of skin condition, hair, sleep…
- Conditions
- Skin Ageing, Healthy Ageing, Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults, Longevity
- Trial name
- IDF-AID-1 (NCT07827651)
- Testing
- Advanced ID
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- IDI Skincare Limited
Healthy Aging
ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy Aging
ELITE, Evidence-Based Longevity Interventions and Targeted Engagement, was a randomized, open-label, two-active-arm Phase IIa pilot conducted at Sheba Medical Center in Ramat Gan, Israel.
- Trial name
- ELITE (NCT07871799)
- Testing
- AgeBiotics AB-01, AgeBiotics AB-02, Metformin
- Where
- Israel
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Healthy Aging
Fractal-based Gait Training in Older Adults
The purpose of the study is to investigate the influence of walking with external visual cues on brain adaptations.
- Trial name
- NCT06507137
- Testing
- Fractal, Isochronous
- Where
- Portugal
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Healthy Aging, Health Promotion
Cost-Effectiveness Analysis of the Healthy Beat Acupunch Regimen on Physical Fitness, Sleep Quality, and Quality of Life Among Community-Dwelling Older Adults
This study will evaluate the effects and preliminary cost-effectiveness of the Healthy Beat Acupunch (HBA) exercise program among community-dwelling older adults in Thailand.
- Trial name
- NCT07868575
- Testing
- Healthy Beat Acupunch (HBA) Exercise Program
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Aging, Frailty
Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults
This is a randomized, double-blind, placebo-controlled, two-arm crossover clinical trial evaluating the effects of nicotinamide mononucleotide (NMN) combined with trimethylglycine (TMG) supplementation, compared to NMN alone.
- Conditions
- Aging, Frailty, Exercise Tolerance, Healthy Male and Female Subjects
- Trial name
- NCT07144527
- Testing
- NMN and TMG (Euexia), Nicotinamide Mononucleotide (NMN)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Scott Silveira
Healthy Aging
Vicia Faba Peptides and Resistance Training in the Elderly
This randomized, double-blind, placebo-controlled clinical trial aims to investigate the effects of supplementation with peptides derived from Vicia faba L.
- Trial name
- NCT07858292
- Testing
- Vicia faba L.-derived peptides, Supervised Resistance Training
- Where
- Brazil
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Universidade Cesumar (UNICESUMAR)
Social Cognition, Healthy Aging
Immersive Group Dance in Virtual Reality and Perceived Social Cohesion in Older Adults
This is a two-arm, parallel-group randomized controlled trial designed to evaluate the effects of an immersive virtual reality (VR)-based group dance program on perceived social cohesion among community-dwelling older adults…
- Conditions
- Social Cognition, Healthy Aging, Loneliness, Social Isolation
- Trial name
- VR-GD-COHESION (NCT07850479)
- Testing
- Immersive VR Group Dance Program, Conventional Light Physical Activity Program
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Sarcopenia, Physical Inactivity
Women in Action: A Multicomponent Intervention for Older Women
"Women in Action" is a quasi-experimental, mixed-methods study evaluating a 16-week multicomponent intervention (supervised strength/aerobic/balance training plus psychoeducational and nutrition-focused behavioral workshops) for…
- Conditions
- Sarcopenia, Physical Inactivity, Menopause, Healthy Aging
- Trial name
- WIA (NCT07860424)
- Testing
- Multicomponent exercise, nutrition, and psychoeducational program
- Where
- 2 sites in Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Healthy, Stroke
Influence of Brain Oscillation-Dependent TMS on Motor Function
Background: When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands.
- Conditions
- Healthy, Stroke, Normal Physiology, Aging
- Trial name
- NCT03288220
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Red Blood Cell Health, Biological Aging
Effect of Pentadecanoic Acid Supplementation on Red Blood Cell Health and Biological Aging in Healthy Older Adults
This Phase II randomized, double-blind, placebo-controlled, parallel-group study will evaluate the effects of pentadecanoic acid (C15:0) supplementation on red blood cell (RBC) health and predicted biological age in healthy…
- Conditions
- Red Blood Cell Health, Biological Aging, Healthy Aging
- Trial name
- NCT07812792
- Testing
- Pentadecanoic Acid
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- ReCellience15, Inc
Fall Prevention in Healthy Aging, Fall
Effect of LiFE-SePBT on Postural Stability in Community-dwelling Older Adults: an Assessor-blinded Randomised Controlled Trial
This study is an assessor-blinded randomised controlled trial investigating the effects of combined Lifestyle-integrated Functional Exercise and Self-initiated Perturbation-based Balance Training (LiFE-SePBT) on postural…
- Conditions
- Fall Prevention in Healthy Aging, Fall, Fall Prevention Training, Postural Control
- Trial name
- LiFE-SePBT (NCT07842094)
- Testing
- Lifestyle-integrated Functional Exercise, Upper limb mobilisation and flexibility training
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- The Hong Kong Polytechnic University
Mild Cognitive Impairment, Cognitive Decline
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function in two groups of individuals: those with mild cognitive impairment…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Healthy Aging
- Trial name
- NCT03954899
- Testing
- melatonin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Natalie Denburg
Exercise Adherence, Healthy Aging
Effectiveness of a Smartphone Chatbot to Improve Exercise Adherence in Older Adults
This randomized controlled trial aims to evaluate the effectiveness of a smartphone-based chatbot in improving adherence to a 12-week home-based multicomponent exercise program in community-dwelling older adults.
- Trial name
- EXEBOT (NCT07832097)
- Testing
- Chatbot-Supported Home-Based Exercise Program, Paper-Based Home Exercise Program Mostrar más líneas
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Aging, Aging, Biological
Evaluation of the Effect of Seasonality on Biological Age in Adults
This research aims to provide insights on how seasonal variations influence biological age and enhance the design and analysis of long-term lifestyle interventions targeting biological clocks.
- Conditions
- Aging, Aging, Biological, Aging, Healthy, BIOLOGICAL CLOCKS
- Trial name
- SeasonAGE (NCT07242833)
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Aging
Protein-Distinct Macronutrient-Equivalent Diet 2
The central hypothesis is that the addition of minimally processed lean pork to a healthy plant-forward low ultra-processed diet will enhance nutrient adequacy, promote muscular fitness, and maintain metabolic functions for…
- Trial name
- PRODMED2 (NCT05581953)
- Testing
- Omnivorous, No meat
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Community-dwelling Older Adults, Neurocognitive Function of Elderly Patients
Modified Otago Exercise Program on Neurocognitive Level and Balance Parameters
This study examined the effect of an eight-week modified Otago Exercise Program on neurocognitive level and balance parameters in community-dwelling older adults.
- Conditions
- Community-dwelling Older Adults, Neurocognitive Function of Elderly Patients, Functional Mobility, Fall Prevention in Healthy Aging
- Trial name
- NCT07831174
- Testing
- Otago Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Alanya Alaaddin Keykubat University
Healthy Aging, Aging
The Effect of Reminiscence Therapy in Older Adults
This randomized controlled study examined the effects of reminiscence therapy on psychological well-being and mindfulness among community-dwelling older adults.
- Trial name
- NCT06964399
- Testing
- Reminiscence therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University