FrailtyNCT06411704
Remote Exercise Video Adaptations to Maximize Physical Activity in Childhood Cancer
An observational study of Frailty and Survivorship, run by St. Jude Children's Research Hospital at 1 site in United States.
Trial summary
The goal of this observational study is to leverage childhood cancer survivor input to adapt video content of a digital video disc-(DVD) delivered evidence-based PA intervention, originally designed for community-dwelling older adults. Read more about this study
- Who is it for?
- Ages 18 to 39 years
- Conditions the study is for
- Frailty, Survivorship, Childhood Cancer
- How many people
- 10 participants
- Where
- 1 siteUnited States
- Study dates
- 6 Jun 2024to Jun 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 39 years
- All sexes
- No healthy volunteers
- Adult
Study population: Long-term childhood cancer survivors with low physical activity.
Who may be able to join
- Participants enrolled in the St. Jude Lifetime Cohort (SJLIFE), aged 18- 39.
- Identifies as low active (self-reports <2 days/week of Physical Activity (PA) for at least 30 minutes over the past 6 months.
- Participant or legal guardian is able and willing to give informed consent.
- Internet access
Who cannot join
- Individuals who cannot speak, read, and/or understand English.
Trial locations and contacts
1 site in 1 country.
United States1 site
St. Jude Children's Research Hospital
Memphis, Tennessee, 38105
About this study
The goal of this observational study is to leverage childhood cancer survivor input to adapt video content of a digital video disc-(DVD) delivered evidence-based PA intervention, originally designed for community-dwelling older adults.
Primary Objective:
- To leverage childhood cancer survivor input to adapt video content for an evidence-based remote exercise intervention.
Read the detailed description
This study is being done to update existing exercise videos to suit adult survivors of childhood cancer to help them exercise at home. Patients will be asked to watch exercise videos designed for older adults and provide feedback during an interview to help researchers update the videos to childhood cancer survivors' preferences
- Conditions
- Frailty, Survivorship, Childhood Cancer
- Medical subject headings
- Frailty, Neoplasms
What is being measured
The primary outcome is the main question the study is designed to answer.
Qualitative interviews
Semi-structured qualitative interviews will be utilized to collect participants' perspectives on relatability, functionality, and relevance of the exercise videos to childhood cancer survivors.
Measured: Day 1
System Usability Scale Questionnaire
Multi-item Likert scored questionnaire to collect participants' perspectives on usability and relevance of the exercise videos. SUS scoring starts by calculating the sum of the score contributions from each item. Each item's score contribution will range from 0 to 4. For items 1,3,5,7,and 9 the score contribution is the scale position minus 1. For items 2,4,6,8 and 10, the contribution is 5 minus the scale position. Multiply the sum of the scores by 2.5 to obtain the overall value of SU. SUS scores have a range of 0 to 100.
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 May 2024
- Study start6 Jun 2024
- Primary completionJun 2027 (estimated)
- Study completionJun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for FrailtyStudies of the same condition, open and under way.
- More trials run by St. Jude Children's Research HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 10 participants (actual)
Sponsor and investigators
- Lead sponsor
- St. Jude Children's Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Kristen Ness, PT, PhD, Principal investigator, St. Jude Children's Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06411704
- Sponsor's protocol ID
- REVAMP
- Other IDs
- NCI-2024-03931
- Status last verified
- Jun 2026
- First submitted
- 8 May 2024
- Last updated
- 24 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Remote Exercise Video Adaptations to Maximize Physical Activity in Childhood Cancer
- ClinicalTrials.gov ID
- NCT06411704
- Acronym / sponsor ID
- REVAMP
- Conditions
- Frailty, Survivorship, Childhood Cancer
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 10 participants (actual)
- Lead sponsor
- St. Jude Children's Research HospitalUniversity, hospital or other
- Study start
- 6 Jun 2024 (actual)
- Primary completion
- Jun 2027 (estimated)
- Study completion
- Jun 2027 (estimated)
- First posted
- 13 May 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to leverage childhood cancer survivor input to adapt video content of a digital video disc-(DVD) delivered evidence-based PA intervention, originally designed for community-dwelling older adults.
Primary Objective:
- To leverage childhood cancer survivor input to adapt video content for an evidence-based remote exercise intervention.
Detailed description
This study is being done to update existing exercise videos to suit adult survivors of childhood cancer to help them exercise at home. Patients will be asked to watch exercise videos designed for older adults and provide feedback during an interview to help researchers update the videos to childhood cancer survivors' preferences
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 39 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Long-term childhood cancer survivors with low physical activity.
Key inclusion criteria (4 listed)
- Participants enrolled in the St. Jude Lifetime Cohort (SJLIFE), aged 18- 39.
- Identifies as low active (self-reports <2 days/week of Physical Activity (PA) for at least 30 minutes over the past 6 months.
- Participant or legal guardian is able and willing to give informed consent.
- Internet access
Key exclusion criteria (1 listed)
- Individuals who cannot speak, read, and/or understand English.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Qualitative interviews
Time frame: Day 1
Semi-structured qualitative interviews will be utilized to collect participants' perspectives on relatability, functionality, and relevance of the exercise videos to childhood cancer survivors.
System Usability Scale Questionnaire
Time frame: Day 1
Multi-item Likert scored questionnaire to collect participants' perspectives on usability and relevance of the exercise videos. SUS scoring starts by calculating the sum of the score contributions from each item. Each item's score contribution will range from 0 to 4. For items 1,3,5,7,and 9 the score contribution is the scale position minus 1. For items 2,4,6,8 and 10, the contribution is 5 minus the scale position. Multiply the sum of the scores by 2.5 to obtain the overall value of SU. SUS scores have a range of 0 to 100.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jun 2026.
- St. Jude Children's Research HospitalLink provided by the sponsor.
- Clinical Trials Open at St. JudeLink provided by the sponsor.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Kristen Ness, PT, PhD principal investigator
St. Jude Children's Research Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Frailty and Survivorship, run by St. Jude Children's Research Hospital at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 24 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Qualitative interviews (time frame: Day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jun 2026; AzTrials last refreshed its copy on 26 Oct 2026.